163 results about "Salvia miltiorrhizae" patented technology

The invention discloses a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases. The traditional Chinese medicine composition is mainly prepared from 81 kinds of traditional Chinese medicine such as radix panacis quinquefolii, placenta hominis, radix salvia miltiorrhizae, herba rhodiolae, fructus schisandrae, head of Chinese angelica, rhizoma chuanxiong, radix polygalae, hirudo, radix notoginseng, fried semen ziziphi spinosae, herba cistanches and radix rehmanniae through mutual matching. The traditional Chinese medicine composition is capable of improving general blood circulation, blood weight and blood vessel elasticity within a shorter time, and meanwhile, damp cold in a body and outer walls of blood vessels can be eliminated and removed out of the body in time; the traditional Chinese medicine composition has the function of repairing internal organs such as the liver, the kidney, the lung and the spleen and is capable of increasing the immunity and the disease resistance of the body in time; the traditional Chinese medicine composition has an obvious treatment or auxiliary treatment rehabilitation function on heart disease, cerebral thrombosis, serious insomnia, astriction, hypertension, hyperglycemia, hyperlipidemia, insufficiency of cerebral blood supply, tinnitus, cervical spondylosis and lumbar spondylosis.

The invention discloses a making method of high-purity tanshinone, which comprises the following steps: (1) heating and refluxing to extract salvia miltiorrhizae root and stalk through 0.1-6.0mol/L acid water/alcohol solution; (2) adsorbing extract through adsorbing column with large-hole resin adsorbent; (3) eluting through water until pH value is 7 first and hydrophilic solvent then; collecting 3-5 column bulks to elute tanshinone completely; (4) evaporating; adding organic solvent; heating; dissolving; crystallizing; or adopting polyamide, gluglucosan gel Sephadex LH-20, MCI GEL CHP20P, C4, C8 or C18 bond phase; obtaining the product.

The invention discloses a preparation method of a pure product of Salvianic acid A sodium, which comprises processing steps: 1. salvia miltiorrhizae is extracted by a hydrothermal method, and an extracting solution is condensed, deposited in alcohol and filtered; 2. a filtrate is condensed, deposited in alcohol and filtered; 3. the filtrate is condensed, added with water and filtered, and the filtrate is put into a macroporous absorption resin column and washed by water; 4. after a water lotion is condensed, the step is carried out in accordance with step (5); or the water lotion is put into a polyamide column and washed by water, and after the water lotion is condensed, the step is carried out according to step (5); 5. the water lotion after condensation is mixed with silicon gel, dried, column-packed and eluted by an organic solvent, and then an eluent is collected, recovered to be dry to obtain dry paste; and 6. the dry paste is taken and dissolved by the organic solvent, and PH value is adjusted, and then the material is stood and crystallized; or the dry paste is taken and dissolved by a solvent, and then put into a Sephadex LH-20 column or reversed-phase silica gel column. The PH value is adjusted by the eluent, and standing and crystallizing are carried out. The Salvianic acid A sodium prepared by the method has purity of more than or equal to 98 percent (standardized by NICPBP in respect of standard substances). Furthermore, the method has low cost, less pollution to environment and easily industrialized production.

The invention discloses an extracting and purifying method of salviol acid A, which comprises the following steps: adopting salvia miltiorrhizae medicine materical crude slice or powder as raw material; using solvent to extract; condensing to obtain the condensate of salvia miltiorrhizae; obtaining high-purity product through protein adsorption and solvent extracting method; using gelatin or egg albumin to sediment salviol acid A; dissolving the salviol acid A through acetone solution; analyzing; extracting through organic solvent to obtain the high-purity product with receiving rate over 0. 3% and purity over 90%. The invention has advantages of reasonable design, high extraction rate, good purity, stable property, simple technique and low manufacturing cost without column chromatography, which is fit for industrial manufacturing.

The invention relates to a natural preservative and a preparation method thereof. The natural preservative is obtained through compounding a radix salvia miltiorrhizae extracting solution, a dark plum extracting solution and a cinnamon extracting solution according to the volume ratio of (1-5): (1-5):1 and then carrying out vacuum concentration, wherein the radix salvia miltiorrhizae extracting solution, the dark plum extracting solution and the cinnamon extracting solution respectively have the concentrations of 45-55mg/mL, 45-55mg/mL and 75-85mg/mL. Raw materials of the natural preservative are all medicinal and edible plants according with the national regulation and natural plants for health care foods, and the natural preservative prepared by using the raw materials accords with the relevant standards of national food additives; secondly, the raw materials and reagents adopted by the invention are safe and nontoxic, and the aims of pure nature and nontoxic or side effect of the natural preservative are achieved; and compared with a traditional preparation process of the natural preservative such as a bamboo leaf extract, the preparation method of the natural preservative has the advantages that the preparation process is simple and convenient, the production cost is low, the prepared natural preservative not only has strong sterilizing and bacterostasis effects, but also contains various substances which has physiological activity and is beneficial to a human body.

The invention relates to a method for preparing salvia miltiorrhizae phenolic acid and its new application in medicine production field. The method comprises following steps: adding water or alcohol into salvia miltiorrhizae for extraction, purifying phenolic acid through column chromatography and purification; washing with alcohol solution, condensing washing solution; adjusting pH, extracting with organic solvent, condensing and drying, getting salvia miltiorrhizae phenolic acid with salvia miltiorrhizae phenolic acid A and B content being above 90%. It is proven by medical effect and pharmacological research that the salvia miltiorrhizae phenolic acid can be used to prepare medicine that treats type-2 diabetes and its complication, including diabetes kidney disease, hepatic disease, and blood rheological property change caused by diabetes. It is tested that the effect of salvia miltiorrhizae phenolic acid and its preparation is strong, and they are safe medicine.

The invention provides a method to extract a polysaccharide from a Danshen root, which is characterized in that the Danshen root is processed by the superfine pulverizing and degreasing and hydrolyzed in the water with pH 4 to 6 for 0.5 to 1.5 hours under 40 to 80 degree centigrade temperature by one or a multiple of a cellulase, a papain, and a pectase, and then processed for 0.5 to 1.5 hours under an ultrasonic wave with a frequency of 59KHz, filtering, and finally the polysaccharide is precipitated from the filtered liquid with an ethanol. The method to extract a polysaccharide from a Danshen root has the advantages of adjusting the enzyme types and dosage based on the fungus polysaccharide extraction process, regulating the process conditions of enzyme process and the ultrasonic wave extraction, realizing to extract Danshen root polysaccharide in a way of low energy consumption and high efficiency.

The invention relates to a method for cultivating rhodiola rosea bag material healthcare pleurotus nebrodensis. A cultivation medium is prepared by, by weight, 20-30 parts of lotus seed hulls, 20-30 parts of cotton stalks, 10-20 parts of sesame stalks, 8-10 parts of bran, 5-6 parts of casava powder, 0.8-1.1 parts of white sugar, 4-5 parts of vinegar residues, 0.5-0.8 part of silkworm excrement, 1-2 parts of salvia miltiorrhizae powder, 2-3 parts of Japanese metaplexis pericarp powder, 1-3 parts of pepper leaf powder, 1-2 parts of rhodiola rosea powder, 2-3 parts of red pine leaf powder, 2-3 parts of Kangxian flower powder, 1-2 parts of bentonite, 1-2 parts of gypsum powder, 2-3 parts of quicklime, 0.2-0.3 part of urea and 10-12 parts of bone soup. The method includes mixing the components according to a proportion, adding water, well mixing, bagging, sterilizing, grafting, producing bacteria in a bacterium producing chamber, replenishing nutrient solution and fruiting pleurotus nebrodensis. The pleurotus nebrodensis cultivated by the method is nutrient-rich and high in content of trace elements, vitamins and calcium and has a rhodiola rosea bag material healthcare function, anti-infection capability is high during pleurotus nebrodensis fruiting, and pleurotus nebrodensis yield is high.

The invention relates to the field of cosmetics, in particular to a composition and an acne-removing cosmetic containing the same. The composition comprises glycolic acid, lactobacillus/pear juice fermented product filtrate, a xanthate bark extract, a white willow bark extract, a rehmannia chinensis root extract, an azadirachta indica leaf extract, a glycine ussuriensis extract, nicotinamide, octyl glycine, a radix sophorae root extract, a radix salvia miltiorrhizae extract, silanediol salicylate, zinc pyrrolidone carboxylate, quercetin, L-magnesium ascorbate phosphate, a centella extract andmenthoxypropanediol. The composition and the acne-removing cosmetic containing the same have the effects of inhibiting induction, inhibiting inflammation and promoting healing.

The invention relates to whitening and brightening composition, whitening and brightening essence as well as preparation methods and applications thereof. The whitening and brightening composition comprises the following active components: phragmites communis, liquorice, radix angelica sinensis, radix salvia miltiorrhizae, fructus corni, fructus lycii, phallus indusiatus, astragalus membranaceus,radix saposhnikoviae, calendula, albizzia julibrissin and rhizoma gastrodiae. The whitening and brightening composition achieves the effect of deeply improving skin by improving skin microcirculationand further brightening skin color, and also has the effects of whitening the skin, resisting oxidation, delaying aging, improving skin brightness, reducing inflammation, relieving and calming skin and the like, and is suitable for preparing whitening and brightening skin care products.

The invention discloses a capsule with hypoglycemic action and process for preparation. The invention adopts panax ginseng, astragalus root, siberian solomonseal rhizome, kudzu root, poria cocos wolf, white atractylodes rhizome, schisandra fruit, gardenia, rhubarb horsetails, salvia miltiorrhizae, and glycyrrhiza which are the homology of medicine and food to be raw material. According to different properties and effective components of each raw material, and each raw material is made into capsules with carriers or findings which can be accepted in pharmacy or bromatology after the raw material is respectively disintegrated, extracted and concentrated, and granulated and the like. The invention has the advantages of simple process, easy taking, and significant curative effect, convenient long-term use, and little side effect, which is an ideal hypoglycemic product.

The invention discloses a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, which is prepared from red sage root extract 60.0-95.0%, pseudo-ginseng extract 2.5-25.0%, and natural borneol or rosewood oil 2.5-15.0%. The content of danshensu in the salvia miltiorrhizae extract is 3-10%, the content of total savianolic acid is 50-75%, the content of salvianolic acid B is 20-45%, the content of total saponins in pseudo-ginseng extract is 70-98%. The composition has evident functions in resisting cerebral ischemia and myocardial ischemia, the curative effect is better than the application of single extract of red sage root or notoginseng, thus providing a more effective and more convenient Chinese medicinal composition and preparation clinically.

The invention discloses foot-bath traditional Chinese medicine composition with functions of relaxing tendons and activating collaterals. The foot-bath traditional Chinese medicine composition is prepared from raw medicine materials in parts by weight as follows: 10-15 parts of whole herb of speranskia tuberculata, 10-19 parts of ramulus cinnamomi, 10-15 parts of ramulus mori, 10-15 parts of herba lycopodii, 10-17 parts of radix clematidis, 10-19 parts of radix angelicae sinensis, 8-15 parts of radix salvia miltiorrhizae, 8-15 parts of semen sinapis albae, 10-17 parts of liquidambar formosana Hance, 8-12 parts of folium artemisiae argyi, 5-10 parts of Sichuan pepper and 3-5 parts of herba asari. The foot-bath traditional Chinese medicine composition has obvious curative effect on degenerative arthritis with symptoms of wind-cold-dampness arthralgia, the total effective rate reaches 87.5%, and the composition has significant difference (P is smaller than 0.05) when compared with a control group; further, the improvement effect on pain, pressing pain, swelling and joint movement degree of a patient is obviously better than that of the control group. Besides, the foot-bath traditional Chinese medicine composition has unique curative effect on neck shoulder pain and lumbocrural pain.

The invention discloses a compound salviae miltiorrhizae pill (condensed pill) and a preparation method thereof and belongs to the field of traditional Chinese medicines. The compound salviae miltiorrhizae pill (condensed pill) is prepared from the following active ingredients in percentage by weight by adopting a superfine grinding method: 75% of salvia miltiorrhizae pill, 24% of pseudo-ginseng and 1% of borneol. Finenesses, measured by an electron microscope, of the salvia miltiorrhizae, pseudo-ginseng and borneol traditional Chinese medicine powders are at a nanometer level (about 0.1*75mu m), so that dissolving and scattering time limits, dissolution rate and utilization rate of traditional Chinese medicines in preparation are greatly improved; besides, the condensed pill also has the characteristics of low dosage, good curative effect, convenient in taking and easiness in absorption; and the compound salvia miltiorrhizae condensed pill is more convenient to take compared with tablets, capsules and granules.

The invention is applied to traditional Chinese medicine medical prescription of rheumatism by the mode of internal and external combination and process for preparation belongs to the traditional Chinese medicine field. The internal prescription materials comprise ormosia 20-40g, madder 20-50g, safflower 20-45g, salvia miltiorrhizae 10-40g, myrrh 15-40g, olibanum 20-40g, glycyrrhiza 20-45g, curcuma longa 20-50g, lumbricus 10-40g, white atractylodes rhizome 15-40g, white phragmites japonica 10-40g, radix clematidis 15-40g, angelica sinensis 20-40g, notopterygium 20-45g, ligusticum chuanxiong 20-50g, red peony root 20-40g, cinnabar 15-40g, ephedra 10-40g, dried ginger 15-40g, steleophaga 20-40g, trogopterus dung 20-45g, rosewood 20-50g, and the external prescription materials comprise ledebouriella root 500-2000g, malt 500-2000g, herba lycopodti 500-2000g, gastrodia elata 500-2000g, ligusticum chuanxiong 500-2000g and myrrh 500-2000g. The internal prescription materials are ground, which are added with honey to form honey pills, and added with water to form water pills, and the external prescription materials are divided to 50 parts. One of the honey pills or the water pills is taken before breakfast, supper and lunch, one dose of the external used medicament is added into water to bath every day, and rheumatic patients use the medicament for both external used and oral administration.

The invention discloses a medication for treating chronic nephritis and a preparation method of the medication. The medication is made by mixing the following medicine according to a proper weight ratio: membranous milkvetch root, leonurus, radix salvia miltiorrhizae, codonopsis pilosula, dodder, atractylodes, Chinese potato, dogwood, and cortex moutan. The medication for treating the chronic nephritis has the functions of clearing heat-toxin, eliminating dampness and dieresis, and nourishing spleen and stomach; when used for treating the chronic nephritis, the medication is quick to take effect, has a short course of treatment, and has a high cure rate.

The invention discloses traditional Chinese medicine for treating cervical spondylosis. The traditional Chinese medicine is prepared by, by weight, radix puerariae 30 g, honey-fried herba ephedrae 10 g, astragalus 30 g, divaricate caposhnikovia roots 20 g, turmeric 15 g, common clubmoss herbs 30 g, herbs of false Chinese swertia 15 g, salvia miltiorrhizae 15 g, flos carthami 10 g, olibanum 15 g, myrrh 15 g, notopterygium 10 g, rhizoma corydalis 20 g, clematis chinensis 20 g, fructus psoraleae 20 g, wolfberries 30 g, schisandga Chinensis baill 10 g, semen cuscutae 30 g, rhizoma drynariae 30 g, cibotium barometz 15 g, radix achyranthis bidentatae 20 g, radix cureumae 20 g, radix polygoni multiflori preparata 30 g, ligusticum wallichii 10 g, rhizoma polygonati 40 g, cistanche salsa 30 g, cynomorium songaricum 20 g, corn cervi pantotrichum 20 g, teasel roots 20 g, stir-baked cortex eucommiae 20 g, geckos 20 g, eupolyphaga 20 g, scorpions 20 g, cinnamon 20 g, human placentas 30 g, hippocampi 20 g, garden balsam stems 30 g, panax notoginseng 20 g, hirudo 10 g, lumbricus 20 g, semen brassicae 30 g, black pepper 30 g, pangolin 20 g, caulis sinomenii 20 g, tripterygium glycosides 10 g, schizophragma integrifolium 20 g, obscured homalomena rhizome 20 g, radix angelicae dahuricae 20 g and honey-fried licorice roots 30 g.

The invention provides an after-sun repairing mask and a preparation method thereof. The mask is prepared from, by weight, 12-18 parts of a flos sophorae extracting solution, 6-12 parts of a radix scutellariae extracting solution, 8-14 parts of a pericarpium citri reticulatae extracting solution, 5-10 parts of a radix angelica sinensis extracting solution, 8-16 parts of honey, 8-14 parts of lemon juice, 5-9 parts of radix salvia miltiorrhizae, 4-8 parts of fructus evodiae, 16-23 parts of pearl powder, 3-6 parts of sea buckthron oil and 2-5 parts of sodium dehydroacetate. The mask is prepared from the pure Chinese herbs, the raw materials and the proportion are carefully selected, the effective active ingredients of the Chinese herbs are fully utilized, a good after-sun repairing effect is achieved, no toxic or side effect is generated, nutrients can be provided for skin and hair, the skin can be tightened, and a certain anti-ultraviolet radiation effect is achieved.

The invention discloses a traditional Chinese medicine ointment for conditioning blood stasis constitution. The traditional Chinese medicine ointment is prepared from components of raw materials in parts by weight as follows: 5-19 parts of radix rehmanniae, 6-17 parts of radix paeoniae rubra, 6-15 parts of radix angelicae sinensis, 3-14 parts of rhizoma chuanxiong, 7-18 parts of herba leonuri, 6-15 parts of peach kernels, 2-10 parts of flos carthami, 1-5 parts of raw radix glycyrrhizae, 6-15 parts of fructus aurantii, 4-13 parts of platycodon roots, 4-13 parts of radix achyranthis bidentatae,5-17 parts of flos rosae rugosae, 3-14 parts of cortex moutan, 10-27 parts of radix puerariae, 3-9 parts of rhizoma cyperi, 5-16 parts of raw pollen typhae, 1-5 parts of cortex cinnamomi, 6-17 parts of earthworms, 13-30 parts of caulis spatholobi, 6-14 parts of radix gentianae macrophyllae, 8-17 parts of radix astragali, 8-17 parts of radix trichosanthis, 7-17 parts of radix salvia miltiorrhizae,6-16 parts of radix notoginseng powder, 7-16 parts of radix rubiae, 12-31 parts of raw fructus crataegi, 5-15 parts of donkey-hide gelatin, 10-22 parts of turtle shell glue, 9-21 parts of tortoise-plastron glue, 20-40 parts of xylitol and 3-9 parts of parched pangolin scales. The traditional Chinese medicine ointment has higher medicine concentration and good taste, is particularly suitable for nourishing tonic in winter, can condition the blood stasis constitution, has no side effects, is completely harmless to the human body and can have certain body building effects.

The invention relates to a Chinese traditional patent medicine, in particular to a Chinese traditional patent medicine for curing apoplexy and apoplectic sequela. The Chinese traditional patent medicine comprises following dry raw materials with part by weight as unit: astragalus 30-60 parts, ligusticum chuanxiong 5-15 parts, rhizome gasdtrodiae 3-15 parts, peach kernel 5-9 parts, salvia miltiorrhizae 5-20 parts, arisaema cum bile 3-9 parts, Chinese yam 10-30 parts, safflower 5-12 parts, achyranthes root 5-15 parts, ginger silkworm 5-12 parts and lumbricus 5-12 parts. Confirmed by clinical experiments, the invention has reasonable formulation, proper compatibility, precise and special medication, curative rate is up to 83.0%, and effective rate is up to 99.3%. The medicament can cure diseases both on symptoms and root cause, and curative effect is solid, the disease can not easily recrudesce after healing, curative method is simple without stimulation and toxic and side effects, and the invention is easily accepted by patients.

The invention discloses a medicament for treating cardiovascular and cerebrovascular diseases, which comprises astragalus root saponin extract 35.0-75%, red sage root extract 15.0-55.0%, panaxtriol saponins extract 2.5-15.0%, and natural borneol or rosewood oil 2.5-15.0%. The content of danshensu in the salvia miltiorrhizae extract is 3-10%, the content of total savianolic acid is 50-75%, the content of salvianolic acid B is 20-45%, the content of total saponins in panaxtriol saponins extract is 80-90%, the content of total saponins in astragalus root saponin extract is 70-98%, the content of Astragaloside IV is 5-15%. The composition has evident functions in resisting cerebral ischemia and myocardial ischemia, the curative effect is better than the application of single extract of red sage root or panaxtriol saponins, thus providing a more effective and more convenient Chinese medicinal composition and preparation clinically.

The invention discloses a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, which comprises astragalus root saponin extract 35.0-75%, red sage root extract 15.0-55.0%, pseudo-ginseng saponin extract 2.5-15.0%, and natural borneol or rosewood oil 2.5-15.0%. The content of danshensu in the salvia miltiorrhizae extract is 3-10%, the content of total savianolic acid is 50-75%, the content of salvianolic acid B is 20-45%, the content of total saponins in pseudo-ginseng saponin extract is 70-98%, the content of total saponins in astragalus root saponin extract is 70-98%, the content of Astragaloside IV is 5-15%. The composition has evident functions in resisting cerebral ischemia and myocardial ischemia, the curative effect is better than the application of single extract of red sage root or notoginseng saponin, thus providing a more effective and more convenient Chinese medicinal composition and preparation clinically.

The invention discloses a Chinese medicinal composition for treating alopecia areata, which is prepared from the following components in parts by weight: 6-9 parts of polygonum multiflorum, 6-9 parts of millettla, 6-8 parts of pomegranate peel, 9-11 parts of unprocessed rehmannia root, 9-11 parts of prepared rehmannia root, 4-6 parts of fructus corni, 4-6 parts of wolfberry, 4-6 parts of psoralen, 5-7 parts of fructus broussonetiae, 5-7 parts of red poney, 10-12 parts of angelica, 10-12 parts of cortex lycii radicis, 10-12 parts of cacumen biotae, 4-6 parts of semen boitae, 4-6 parts of spina date seed, 4-6 parts of tuber fleeceflower stem, 9-11 parts of salvia miltiorrhizae, 4-6 parts of sesame flower, 4-6 parts of cockscomb, 5-7 parts of dodder, 5-7 parts of raspberry, 5-7 parts of wild chrysanthemum, 8-10 parts of tribulus terrestris and 8-10 parts of semen torreya. The Chinese medicinal composition disclosed by the invention has the efficacies of nourishing the kidney and the liver and nourishing the blood to expel wind, has a good effect of treating the alopecia areata and has no any side and toxic effect.

The present invention relates to a medicine for dysmenorrhea, belonging to the traditional Chinese medicine field, composed of frankincense 3-12g, cattail pollen 4-8g, cordyceps 3-9g, prepared myrrh 2-6g, radix salviae 2-8g, angelica 1-6g, Sichuan peony root 1-7g, trogopterus dung 4-8g, auricularia polytricha 2-6g, radix salvia miltiorrhizae 3-8g, American ginseng 8-12g, Chuanjizi 4-8g, prepared rehmannia root 2-7g, fleece-flower root 3-9g, parched white peony root 1-7g, panax notoginseng 2-6g and licorice 2-6g. The medicine has features of good curative effect, quick effect, both temporary and permanent cures and low recurrence rate.