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Dropping pills for treating sudden deafness and method for preparing the same

A technology of sudden deafness and dropping pills, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pill delivery, etc. It can solve problems such as damage to the middle ear structure, middle ear adhesion, and side effects , to achieve the effect of not easy to relapse, definite curative effect, and no side effects

Inactive Publication Date: 2008-06-11
周宣岩 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional systemic application of steroid hormones in clinical treatment of sudden deafness has achieved certain results, but high-dose systemic application can cause obvious toxic side effects, such as infection, ulcer disease, osteoporosis, etc.
Moreover, the main action site of hormones is the inner ear, so many scholars now perform local injection of hormones into the tympanum and have achieved good results. However, as a traumatic treatment, it may damage the structure of the middle ear, causing middle ear infection or middle ear infection. Adhesion

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Take Astragalus, Pueraria lobata, Chuanxiong, Shichangpu, Danshen, Bupleurum, Cohosh, Lycium barbarum, Scutellaria, Earthworm, Codonopsis, Peach kernel, Safflower, Uncaria, and boil 1 to 5 times, 0.5 to 2 hours each time , Combine the decoction, concentrate an appropriate amount, add 1 to 4 times the amount of ethanol, stand for 12 to 36 hours for precipitation, take the supernatant, recover the ethanol, and concentrate into a thick paste with a relative density of 1.1 to 1.5 for later use. Put the polyethylene glycol-6000 into a dry container and heat it to melt, take the above thick paste and add it to the molten auxiliary material polyethylene glycol-6000, and mix it uniformly at 80-95°C to obtain the medicinal solution to be dripped. The liquid paraffin of the condensing agent is pre-cooled to 10-15°C, and the above-mentioned medicinal liquid is dropped into the condensing agent drop by drop at a dropping rate of about 30 drops / min, taken out, wiped off the condensing a...

Embodiment 2

[0048] Take astragalus, Pueraria lobata, Chuanxiong, Shichangpu, Danshen, Bupleurum, cohosh, wolfberry, scutellaria, earthworm, Codonopsis, peach kernel, safflower, Uncaria, and boil 2 to 4 times for 0.8 to 1.5 hours each time , Combine the decoction, concentrate an appropriate amount, add 1.5 to 3 times the amount of ethanol, stand for 18 to 30 hours for precipitation, take the supernatant, recover the ethanol, and concentrate into a thick paste with a relative density of 1.2 to 1.45 for later use. Put the polyethylene glycol-1000 into a dry container and heat it to melt, take the thick paste and add the molten polyethylene glycol-1000, mix it evenly at 80~95℃, drip into the cooled 5~10℃ liquid paraffin In the middle, the drops are made into drop pills, removed, and the paraffin wax is wiped off.

Embodiment 3

[0050] Take Astragalus, Pueraria lobata, Chuanxiong, Shichangpu, Danshen, Bupleurum, Cohosh, Lycium barbarum, Scutellaria, Earthworm, Codonopsis, Peach kernel, Safflower, Uncaria, and boil 1 to 5 times, 0.5 to 2 hours each time , Combine the decoction, concentrate an appropriate amount, add 1 to 4 times the amount of ethanol, stand for 12 to 36 hours for precipitation, take the supernatant, recover the ethanol, and concentrate into a thick paste with a relative density of 1.3 to 1.4 for later use. Put polyethylene glycol-1500 into a dry container and heat it to melt, take the thick paste and add melted polyethylene glycol-1500, mix it evenly at 80~95℃, and drop it into cooled 6~8℃ liquid paraffin. In the middle, the drip is made into drip pills, take it out and wipe off the condensing agent to get drip pills.

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Abstract

The invention belongs to the field of traditional Chinese medicine and process for preparation, which is a dropping pill used for curing sudden deafness. Basic ingredients of the invention are constituted by following medicaments: astragalus root, kudzu root, ligusticum chuanxiong, acorus gramineus soland, salvia miltiorrhizae, bupleurum root, cimicifuga foetida, medlar, scutellaria root, lumbricus, lanceolata, peach kernel, safflower, uncaria and proper amount of auxiliary materials, wherein the auxiliary materials are chosen from carbowax-1000-8000 or the mixture of the compositions. The highly effective and quick-effective function of the invention is particularly suitable for curing sudden deafness, the invention can improve the blood supply of inner ear, advance the functional recovery of hair cells of the inner ear, inhibit self immune response, clear free radicals of body and improve auditory acuity, and the sudden deafness can not easily recur after being cured. The invention is a pure traditional Chinese medicine preparation with no side effect and easy administration, which contains no hormone substance. The invention overcomes the defects and shortcomings of original traditional Chinese medicine preparation. The invention can be made into tablets, granules, capsules, pills, oral liquid, dropping pills and the like, and can be used for curing patients with other types of sensorineural hearing loss or tinnitus.

Description

Technical field: [0001] The invention relates to a Chinese medicine for treating sudden deafness and other diseases and a preparation method thereof, in particular to a dripping pill. Background technique: [0002] Sudden deafness is a kind of sensorineural hearing loss with complex and incompletely clear causes. It belongs to the category of "deafness" in traditional Chinese medicine. Hearing falls to the lowest point within a few hours or days, and the incidence is increasing year by year. It is an otology emergency. one. Current studies speculate that the main causes of sudden deafness are as follows: inner ear blood supply disorders, viral infections, autoimmune diseases, genetic factors, and perilymphatic fistulas. Therefore, there is no definite treatment plan for sudden deafness, and the treatment is mainly based on the presumed cause, which lacks specificity. Many treatment programs based on the cause of the disease have been applied to the clinic and have achieved varyin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61K9/20A61K47/34A61P27/16A61J3/06A61K35/62A61K47/10
Inventor 周宣岩陶谦张峰
Owner 周宣岩
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