Patents
Literature
Patsnap Copilot is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Patsnap Copilot

141 results about "Ulcer disease" patented technology

Peptic ulcer disease is a condition in which there are painful sores or ulcers in the lining of the stomach or the first part of the small intestine (the duodenum). Normally, a thick layer of mucus protects the stomach lining from the effect of its digestive juices. But many things can reduce this protective layer, allowing for ulcers to occur.

Compostions with enhanced bioavailability and fast acting inhibitor or gastric acid secretion

The present invention relates to the use of pharmaceutically acceptable zinc salts, preferably water soluble zinc salts alone or optionally, in combination with one or more of a protein pump inhibitor (PPI), H2 blocker, anti-H. pylori antibiotic / antimicrobial, cytoprotective agent or a combination agent as otherwise described herein for providing fast action with optional long duration effect in reducing gastric acid secretion, raising the pH of the stomach during resting phase as well as decreasing the duration of stomach acid release during a secretagogue phase and for treating conditions including gastroesophageal reflux disease (GERD), non-erosive reflux disease (NERD), Zollinger-Ellison syndrome (ZE disease), ulcer disease, and gastric cancer, as well as preventing or reducing the likelihood of ulcer disease. In addition, the present methods are useful for treating patients who are non-responsive to proton pump inhibitors (PPI) and as an alternative to traditional therapies or conditions which are caused by rapid and complete inhibition of secretagogue induced acid secretion. The present invention also relates to the use of one or more water soluble zinc salts, administered in combination with a therapeutic compound or agent (second therapeutic agent) which may be delivered orally with enhanced bioavailability (compared to compounds which are administered in the absence of water soluble zinc salts) or other favorable benefits. In addition, therapeutic agents which exhibit sensitivity to low pH may be advantageously orally administered in combination with an effective amount of at least one water soluble zinc salt. Compositions according to the present invention exhibit greater bioavailability of the active agent when formulated in combination with a water soluble zinc salt in oral dosage form than when administered with the water soluble zinc salt.
Owner:YALE UNIV

Lactone formulations and method of use

Compounds of Formula Ia and Ic having a lactone structure and an methylene group at the alpha-position of the lactone structure and methods for using and making the compounds have been disclosed. The lactone compounds can be reacted with an neucleaphilic agent to open the lactone ring to a compound of Formula Ib. The lactone of Formula Ia and its functional derivatives have been isolated from Securidaca virgata. These compounds are referred to as LMSV-6 or Securolide™. The purified compounds have demonstrated activity in assays for anti-bacterial and anti-fungal activities, and for treating proliferation disorders such as cancer. Based on the in vitro assays, the lactones are useful for treating proliferation disorders including, for example, breast cancer, colon cancer, rectal cancer, stomach cancer, pancreatic cancer, lung cancer, liver cancer, ovarian cancer, esophageal cancer, and leukemia. They are also effective for treatment of bacterial and fungal infections, including treatment of peptic ulcer disease, gingivitis and periodontitis. The lactone and its derivatives has the following chemical structure:
wherein R1-R9 and Y1-Y3 taken independently are preferably a hydrogen atom, a halogen atom, a hydroxyl group, or any other organic groups or groupings which optionally include a heteroatom such as oxygen, sulfur, or nitrogen groupings in linear, branched, or cyclic structural formats; Z and X are independently and preferably a heteroatom such as oxygen, sulfur, or nitrogen groupings in linear, branched, or cyclic structural formats; and Z′ may a hydrogen atom, a halogen atom, a hydroxyl group, or any other organic groups or groupings which optionally include a heteroatom such as oxygen, sulfur, or nitrogen groupings in linear, branched, or cyclic structural formats.
Owner:MAGNACHEM INT LAB

Chinese herbal medicine feed additive for preventing and assisting in treatment of shrimp and crab shell ulcer disease

The invention relates to a Chinese herbal medicine feed additive for preventing and assisting in treatment of the shrimp and crab shell ulcer disease. The Chinese herbal medicine feed additive is characterized by comprising the following raw materials for compatibility: fresh garlic, fresh herba portulacae, dandelion, herba hedyotis, scutellaria baicalensis, bunge corydalis herb, isatis root, cordate houttuynia, cyrtomium fortunei, edible salt and a carrier. A preparation method of the feed comprises the following steps: firstly, mixing and homogenizing the fresh garlic, the fresh herba portulacae and the edible salt; then, mixing the obtained product with the dandelion, the herba hedyotis, the scutellaria baicalensis, the bunge corydalis herb, the isatis root, the cordate houttuynia, the cyrtomium fortunei and the carrier and grinding the mixture through a grinder to obtain mixed materials; and carrying out mixing and sieving processing to prepare the Chinese herbal medicine feed additive for preventing and assisting in treatment of the shrimp and crab shell ulcer disease. After the feed additive is added, morbidity of the shrimp and crab shell ulcer disease can be reduced and the hazard of the shrimp and crab shell ulcer disease is reduced; feeds suitable for the feed additive do not need to be added with antibiont medicaments; and shrimp and crab products produced by utilizing the Chinese herbal medicine feed additive are nuisanceless environmental-friendly foods.
Owner:YANCHENG INST OF TECH

Pharmaceutical composition comprising a proton pump inhibitor and a prebiotic for the treatment of ulcerous lesions of the stomach and duodenum

A pharmaceutical composition comprising proton pump inhibitors and prebiotics is proposed for the treatment of gastric and duodenal ulcer, this allowing effective ulcer treatment and eradication of H. pylori from the gastric and duodenal mucosa to be carried out without using wide-spectrum antibiotics. The comprehensive treatment of ulcer disease associated with a helicobaterial infection using a pharmaceutical composition of a PPI and a prebiotic makes it possible, in conditions of an elevated pH of the stomach contents, actively to stimulate the growth of lactobacilli in the upper sections of the gastrointestinal tract, including the duodenum, and substantially to increase the titre of lactobacilli, which are antagonists of H. pylori, which greatly improves the effectiveness of the ulcer treatment.; The high clinical effectiveness and safety resulting from the synergistic action of the proton pump inhibitor and the prebiotic in the upper sections of the gastrointestinal tract, the absence of side effects and recurrences, and also the level of compliance to the combined treatment provided by the claimed pharmaceutical composition indicate that the proposed formulation is a promising new means for the treatment of gastric and duodenal ulcer. Use of the claimed composition dramatically reduces the number of recurrences of the illness.
Owner:亚历山大·弗拉基米罗维奇·季科夫斯基

Formula and preparation method of paste capable of removing slough and promoting tissue regeneration

The invention relates to medical technology and in particular relates to a formula and preparation method of paste capable of removing slough and promoting tissue regeneration for treating skin ulcer. The formula of the paste capable of removing slough and promoting tissue regeneration is characterized by comprising the following components in parts by weight: 50-70 parts of Chinese angelica, 15-20 parts of angelica root, 8-12 parts of bletilla, 8-10 parts of amber, 50-70 parts of beewax, 5-7 parts of lithospermum, 8-10 parts of liquorice, 450-500 parts of sesame oil and 10-12 parts of dragon's blood. The paste capable of removing slough and promoting tissue regeneration is a pure traditional Chinese medicine preparation formed by combining the modern science and technology on the basis of inheriting excellent achievements of the formers, has the effects of removing slough, drawing out pus, pushing toxicity and promoting tissue regeneration, has the advantages of definite curative effect, low cost and no obvious toxic and side effect and is applicable to a patient with canker caused by skin ulceration, especially during treatment of chronic ulceration such as bedsore and diabetes gangrene. The medicine can obviously promote ulcer healing and significantly improve cure rate.
Owner:FIRST HOSPITAL OF SHANXI MEDICAL UNIV

Pitcher plant health herbal tea

The invention relates to pitcher plant health herbal tea, which mainly comprises 70 to 90 percent of pitcher plant, 1 to 10 percent of black bone tea, 2 to 15 percent of wild tea and 1 to 10 percent of mallotus root, also comprises Chinese medicinal components such as spreading hedyotis herb, salvia miltiorrhiza bunge, grosvener siraitia, desmodium and the like, has main effects of clearing away heat and toxic material, protecting lung and liver, stopping pain and illness, eliminating phlegm and stopping cough, dispelling three fats, dispelling mallnutrition and indigestion syndrome in children, and stimulating the appetite and relieving dyspepsia, and has effects of prevention and adjunct therapy of hypertension, hepatitis with jaundice and hepatocirrhosis; and because the pitcher plant has the effects of moistening lung and stopping cough, clearing heat and promoting dieresis and dispelling calculus, releasing toxin and removing swelling, and treating lung dryness and hemoptysis, cold cough, whooping cough, jaundice, diarrhea, lithangiuria and the like, the pitcher plant can be also used for preventing and treating diseases such as stomach and duodenum ulcer diseases, hypertension, diabetes, boils and sores and carbuncle swelling and the like, and the development of the pitcher plant health herbal tea has important significance.
Owner:梁惠兴
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products