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26 results about "Otology" patented technology

Otology is a branch of medicine which studies normal and pathological anatomy and physiology of the ear (hearing and vestibular sensory systems and related structures and functions) as well as their diseases, diagnosis and treatment. Otologic surgery generally refers to surgery of the middle ear and mastoid related to chronic otitis media, such as tympanoplasty, or ear drum surgery, ossiculoplasty, or surgery of the hearing bones, and mastoidectomy. Otology also includes surgical treatment of conductive hearing loss, such as stapedectomy surgery for otosclerosis.

Otological disease prediction method based on multi-modal data fusion and confidence evaluation

The invention relates to the field of otological disease prediction, in particular to an otological disease prediction method based on multi-modal data fusion and confidence evaluation. According to the technical scheme, the method comprises the following steps: acquiring an otoendoscope digital image, broadband tympanic image measurement data and structured or unstructured clinical information; carrying out integrity verification and quality verification on the collected data, and checking whether the resolution of the digital image of the otoendoscope meets the minimum pixel requirement or not and whether the information is complete or not; preprocessing the otology data and extracting multi-modal features, and extracting an ear endoscope digital image feature vector, a feature vector representing broadband tympanic chamber image data and a clinical information feature vector; fusion is carried out after feature extraction, and confidence evaluation and recurrence risk prediction are carried out after fusion. According to the method, the three-mode data of the image, the physiological signal and the clinical text are deeply fused through the attention mechanism, so that the prediction accuracy of the otological diseases is remarkably improved. The method is suitable for otological disease prediction.
Owner:SICHUAN AGRI UNIV

Glasses wearing auxiliary device for otology patient after operation

The utility model provides a glasses wearing auxiliary device for otology patients after operation, and belongs to the technical field of medical auxiliary devices. The device comprises a glasses frame and an elastic bridle, glasses legs are arranged at one end of the glasses frame, fixing piles are arranged at the other end of the glasses frame, a clamp and a fixing sleeve are arranged at the two ends of the elastic bridle respectively, the clamp is used for being clamped and fixed to the fixing piles, and the fixing sleeve is used for being detachably installed at the ends of the glasses legs. And a telescopic adjusting mechanism is arranged in the middle of the elastic bridle. The telescopic adjusting mechanism in the middle of the elastic bridle comprises an inserting block and a buckle which are matched with each other in an inserting mode. The middle of the elastic bridle is broken, one end of the middle of the elastic bridle is fixedly connected with the buckle, and the other end of the middle of the elastic bridle is connected with the inserting block in a winding mode. According to the utility model, the otology patient can conveniently and quickly wear the glasses after the operation, the universality is strong, and the overall use effect is good.
Owner:BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Cutter handle straight accessory for otologic operation

The cutter handle straight accessory comprises a water injection sleeve, a front end base is arranged on the rear side of the water injection sleeve, a C-shaped sliding groove is formed in the circumferential face of the front end base, a rotating ball is connected into the C-shaped sliding groove in a rolling mode, the circumferential face of the front end base is connected with a rotating sleeve in a sleeved mode, and the rotating sleeve is connected with the rotating ball in a rolling mode. A positioning sliding groove is formed in the inner ring of the rotating sleeve and is in rolling connection with the rotating ball, rotating sleeve sealing rings are fixedly connected to the front portion and the rear portion of the positioning sliding groove correspondingly, the circumferential faces of the rotating sleeve sealing rings abut against the front end of the front end base, and bolt pin holes are formed in the rear end of the front end base. A first cylindrical pin abuts against the interior of the bolt pin hole, a clamping sleeve is connected to the circumferential face of the first cylindrical pin in a clamped mode, and the clamping sleeve abuts against the rear end of the front end base. Through the design of the C-shaped sliding groove and the rotating ball, the rotating sleeve can achieve smooth rotating motion and is crucial to fine operation in the otology operation, and the accuracy and the success rate of the operation can be improved.
Owner:CHENGDU LEIHUO TECHNOLOGY CO LTD

Ear disease prediction method based on multi-modal data fusion and confidence evaluation

The present application relates to the field of otology disease prediction, and particularly relates to an otology disease prediction method based on multi-modal data fusion and confidence evaluation. The technical scheme comprises: collecting an ear endoscope digital image, wideband tympanometry measurement data, and structured or unstructured clinical information; performing integrity check and quality check on the collected data, checking whether the ear endoscope digital image resolution meets the minimum pixel requirement and whether the information is complete; then performing otology data preprocessing and multi-modal feature extraction, extracting an ear endoscope digital image feature vector, a feature vector representing wideband tympanometry data, and a clinical information feature vector; after feature extraction, fusion is performed, and after fusion, confidence evaluation and recurrence risk prediction are performed. The present application significantly improves the accuracy of otology disease prediction by deeply fusing image, physiological signal and clinical text three modal data through an attention mechanism. The present application is suitable for otology disease prediction.
Owner:SICHUAN AGRI UNIV

Otology medicine knowledge base construction method and device and storage medium

The invention discloses an otology medicine knowledge base construction method and device and a storage medium. The method comprises the following steps: acquiring an otology knowledge data set, an otology clinical case data set and a plurality of ear CT images, identifying a plurality of first medical entity words in the otology knowledge data set and a plurality of second medical entity words in the otology clinical case data set, and extracting quantitative image features corresponding to a plurality of image sub-regions in the plurality of CT images; according to the multiple first medical entity words, the multiple second medical entity words and the quantitative image features corresponding to the multiple image sub-regions, a heterogeneous graph network is constructed, and the otology medicine knowledge base is generated based on the heterogeneous graph network, so that image data-clinical parameters-otology professional knowledge data can be effectively integrated; the otology professional knowledge is deeply associated with the image data and the clinical parameters, and unified structured data is generated, so that the otology medical knowledge base capable of integrating the otology image data and the clinical parameters is constructed.
Owner:BEIJING FRIENDSHIP HOSPITAL CAPITAL MEDICAL UNIV +1

Fixing device for continuous perfusion, flushing and recycling in otology department

ActiveCN224220507UEnemata/irrigatorsEar treatmentContinuous perfusionControl theory
The utility model discloses a fixing device for otology continuous perfusion flushing recovery, which comprises a placing bin, a reflux treatment bin, a pump body and a flusher, a fixing auxiliary mechanism is arranged on the inner wall of the inner side of the placing bin, and the fixing auxiliary mechanism comprises a control frame fixedly connected to the inner wall of the inner side of the placing bin; a control rod is slidably connected to the interior of the control frame, and a clamping frame is fixedly connected to one end of the control rod. According to the fixing device for continuous perfusion, flushing and recycling in the otology department, the rotating shaft drives the regulation and control wheel to rotate by rotating the rotating shaft, the regulation and control wheel pushes the control rod to move by utilizing the shape of the regulation and control wheel, and the clamping frame is clamped on the outer side of the backflow treatment bin; the purpose that the clamping frame can conveniently limit the backflow treatment bin through the limiting frame is achieved, then the backflow treatment bin can be conveniently installed at the bottom of the inner side of the containing bin, and the situation that installation and fixation of the backflow treatment bin fail is avoided.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Otological drug delivery device

The present invention relates to the technical field of otology ear drop administration, and discloses an otology administration device, comprising a thermos cup, an isolation cup, an air cavity, a hot air component, a control screen, a support component, a suction cup, a temperature sensor chip, a shaking component, a baffle, a gusset plate, a top plate, a support rod, and a dropper. The present invention is easy to install and remove medicine bottles, heats the medicine liquid by blowing air, and simultaneously vibrates the medicine liquid, thereby improving the heating rate; temperature monitoring is performed by the temperature sensor chip, thereby preventing the temperature of the medicine liquid from being too high; the dropper dripping method replaces the direct dripping method of the medicine bottle, thereby keeping the medicine bottle farther away from the patient's ear during use, preventing the medicine bottle from excessively blocking the nurse's field of vision, and enabling the nurse to complete the operation quickly; in order to prevent the medicine liquid from cooling down while staying in the air after leaving the medicine bottle due to low ambient temperature, the present invention is provided with an air pipe, which, on the one hand, sprays hot air toward the dropper to prevent the medicine drops from cooling down, and on the other hand, accelerates the rate at which the medicine drops flow through the dropper into the patient's ear.
Owner:THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV

Pasting film for otologic operation

ActiveCN223831190UEar treatmentSurgical drapesEar operationsThin membrane
The utility model discloses a pasting film for otology operation, which belongs to the technical field of medical consumables and comprises a film body, a liquid collecting hopper connected with the film body for forming, a connecting film, a second opening arranged on the surface of the connecting film and corresponding to the first opening, and the liquid collecting hopper is connected with the film body for forming. And a strip-shaped side opening communicated with the second opening is formed in the surface of the connecting film. The ear protection film has the beneficial effects that the connecting film, the second opening and the strip-shaped side opening are arranged, so that the second opening of the connecting film corresponds to the first opening in the film body, and the film body is firstly adhered to the ear of a patient, so that the ear penetrates out of the first opening; the connecting film is attached to the film body after being sleeved on the ear through the strip-shaped side opening, the design is tightly attached to the outline of the ear, flushing or perfusate permeation is effectively blocked, pollution of an operation area and discomfort of the ear of a patient are avoided, cleanliness and comfort of the ear operation are improved, and the postoperative infection risk is reduced.
Owner:亳州市人民医院

Ear canal drug delivery device for otology

The auditory meatus dosing device comprises a dosing head arranged on an ointment tube, the dosing head comprises a tube cap used for being in butt joint with the ointment tube and a medicine tube used for stretching into an external auditory meatus, one end of the medicine tube is detachably connected with a medicine spoon, and the medicine spoon comprises a lantern ring and a medicine tongue. The medicine tongue is provided with a medicine containing face used for containing and applying medicine and a medicine applying face used for evenly applying ointment. The administration head can be directly mounted on a medicinal ointment tube, so that ointment can be pushed to the medicine containing surface of the medicine spoon by squeezing the ointment tube so as to apply the ointment to an affected part in an ear canal, and then the ointment tube is turned over to enable the medicine applying surface of the medicine spoon to face the affected part, so that the ointment can be uniformly applied by the medicine spoon; therefore, the medicine containing surface of the medicine spoon can be used for taking a trace amount of medicine to control the dosage, and the medicine smearing surface can be used for accurately applying the medicine to an affected part, so that medicine waste is avoided, and the treatment effect of auditory meatus medicine application can be ensured.
Owner:SHANXI BETHUNE HOSPITAL (SHANXI ACAD OF MEDICAL SCI SHANXI HOSPITAL OF TONGJI HOSPITAL AFFILIATED TO TONGJI MEDICAL COLLEGE OF HUAZHONG UNIV OF SCI & TECH SHANXI MEDICAL UNIV THIRD HOSPITAL SHANXI MEDICAL UNIV THIRD CLINICAL COLLEGE OF MEDICINE)

Listening test assist device

The utility model relates to the technical field of hearing tests in the otology department, in particular to a hearing test assist device, and provides the following scheme aiming at the problems that when a user tests, the experience feeling is poor, the user is easy to test, the user moves randomly and the test result is influenced due to the fact that part of existing equipment cannot be effectively adjusted according to the head circumference of the user. The device comprises a main board; the multiple adjusting plates are arranged on the main plate, an L-shaped connecting handle is fixedly installed on the main plate, plate grooves are formed in the multiple adjusting plates, the multiple plate grooves are matched with the main plate, elastic bands and multiple fixing plates are fixedly installed on the multiple adjusting plates, and fixing shafts are rotationally installed on the multiple adjusting plates; according to the utility model, the tightness of the elastic band is adjusted through the adjuster, so that the head cover is attached to the head circumference of a user, and the adjusting plate and the main plate are synchronously adjusted, so that the device is fully attached to the head circumference of the user.
Owner:GUANGDONG HUAAN TESTING MEDICAL TECH CO LTD

Portable auricular point positioning projection device

The invention relates to the technical field of otology, in particular to a portable auricular point positioning projection device, which comprises a shell part, an image acquisition module, an auricular point identification system, an acupoint indication module and a display module, the shell part is provided with an occlusion groove, so that the projection device is fixed by the mouth of a user, and even if the head of the user shakes, the projection device can be fixed. The shell part is also relatively fixed relative to the head, and only slightly deviates in actual use, so that high-definition images of ears can be shot in a close range through the image acquisition module, projection images and projection coordinate systems with auricular point position coordinates can be generated through the auricular point identification system, and the projection images and the projection coordinate systems are projected to the ears through the acupoint indication module; real-time ear images are displayed through the display module, the two hands can be freed, auricular point pressing, magnet therapy, massage and other operations can be conducted on the acupuncture points indicated by the acupuncture point indication module, the outer shell part can be changed into a short rod shape by rotating the second shell, and storage and carrying are convenient.
Owner:张立茹

Abnormal feature extraction method and device for otology multi-modal data and medium

The invention discloses an abnormal feature extraction method and device for otology multi-mode data and a medium, and the method comprises the steps: carrying out the abnormal feature extraction of the otology multi-mode data of a user according to a comprehensive model, and obtaining the abnormal features of the otology data; wherein the comprehensive model is obtained by training the initial model according to positive and negative sample pairs and pseudo labels, and the positive and negative sample pairs are generated by pairing joint representation vectors of different users. According to the abnormal feature extraction method and device for otology multi-modal data and the medium, the combined representation vector is generated to integrate the image and the text data so as to break the modal barrier, and the positive and negative sample pairs and the pseudo labels are combined to train the initial model, so that the obtained comprehensive model can master the multi-modal association logic, and the accuracy of the abnormal feature extraction of the otology multi-modal data is improved. The abnormal features can be directly and efficiently extracted, and the problems that the abnormal feature extraction efficiency is low and the rapid processing requirement of the otology multi-modal data is difficult to meet due to the lack of an analysis mechanism for efficiently integrating the otology multi-modal data can be solved.
Owner:SHENSHAN MEDICAL CENT MEMORIAL HOSPITAL OF SUN YAT-SEN UNIV

Disposable hair band for skin preparation area in otology operation

The utility model belongs to the technical field of medical instruments, and particularly relates to a disposable hair band for a skin preparation area in an otology operation, which comprises a hair band component, a hair band main body and ear through holes arranged on two sides of the hair band main body, the hair band body comprises a base cloth layer, an elastic layer arranged on the inner side wall of the base cloth layer, a nylon rib arranged in the elastic layer and a sweat absorbing layer arranged on the inner side wall of the elastic layer. The hair binding assembly comprises a hair binding net bag arranged at the top of the hair band main body, a fixing sleeve arranged at the top of the hair binding net bag and a fixing binding band arranged in the fixing sleeve; the hair fixing device is reasonable in structure, in the using process, hair of a female patient can be conveniently fixed, the operation view can be fully exposed, and the success rate of an operation can be increased.
Owner:THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Postoperative nursing fixing device

The utility model relates to the technical field of otology, in particular to a postoperative care fixing device which comprises two mounting rings. Two mounting plates; the number of the pressing structures is two, and the two pressing structures are used for fixing the two lugs respectively; the device is fixed through the fixing structure; after the device is arranged on the head of a patient in a sleeving mode through the two mounting plates, the two mounting rings are pressed on the two ears of the patient respectively, the first connecting belt and the second connecting belt are used for winding the device on the head of the patient, and the first connecting belt penetrates through the sleeving rings and is fixed through adhesion of the hook-and-loop fasteners and the hook-and-loop fasteners; the medicine applying nursing positions of the ears of the patient are fixed through the pushing blocks, during medicine changing, the rotating rings are rotated on the supporting shafts, the corresponding pushing blocks are taken out of the mounting rings, nursing medicine changing of the ears of the patient is conducted through the mounting rings, and meanwhile after medicine changing is completed, the pushing blocks are reset through the torsional springs so that postoperative nursing fixing of the ears of the patient can be kept.
Owner:THE THIRD MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL

Visualizing devices, systems, and methods for otology and other uses

Devices, systems, and methods can be employed to facilitate indirect viewing of a cavity, such as, but not limited to, a middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and surgery in the outer ear, middle ear, and / or inner ear, in order to diagnose and / or treat conditions, including but not limited to hearing loss and other ear conditions. In particular implementations, a surgical microscope is used in conjunction with a reversing lens and a distal lens. In some cases, the distal lens traverses a membrane or septum, such as, but not limited to, the tympanic membrane. In some embodiments, the distal lens can be an assembly that combines two or more lenses. For example, in some cases, wide angle lenses, zoom lenses, other variously shaped lenses, and / or prisms can be used in the distal lens.
Owner:SPIRAL THERAPEUTICS INC

Devices, systems, and methods of otology

Devices, systems, and methods can be used to facilitate performing procedures in the outer, middle, and / or inner ear in order to diagnose and / or treat diseases, including but not limited to hearing loss and other ear diseases. For example, devices, systems, and methods are described herein that include instruments and techniques to minimize invasiveness and / or enhance the efficacy of procedures performed in the outer, middle, and / or inner ear space, such as, for example, mastoidectomy, tympanoplasty, cholesteatoma treatment, otosclerosis treatment, and Eustachian tube treatment.
Owner:SPIRAL THERAPEUTICS INC

Otology cartilage fascia former

The otology cartilage fascia former comprises a fixing plate and a clamping plate magnetically attracted to the top face of the fixing plate, the surface area of the fixing plate is larger than that of the clamping plate, a clamping portion is fixedly arranged on the bottom face of the fixing plate, and the central axis of the clamping portion and the central axis of the fixing plate are collinear. By arranging the fixing plate and the clamping plate magnetically attracted to the fixing plate, the cartilage or the fascia can be easily clamped, the cartilage or the fascia is evenly stressed, the situation that the operation quality is affected due to the fact that clamping is too tight or too loose is avoided, meanwhile, by arranging the clamping part, in the cutting process of the outer edge of the cartilage or the fascia, the operation quality is not affected, and the operation efficiency is improved. The index finger and the middle finger can move back and forth in a staggered manner, so that the fixing plate can be conveniently rotated, and a doctor can conveniently cut cartilage or fascia for the second time.
Owner:THE FOURTH HOSPITAL OF HEBEI MEDICAL UNIVERSITY (HEBEI CANCER HOSPITAL)

Fascia cutting device for otology operation

The invention belongs to the technical field of fascia cutting devices, and provides an otologic operation fascia cutting device which comprises a holding handle, a fixing device and a fixing device. One end of the holding handle is fixedly connected with a fixing pipe, a sliding rod is slidably installed in the fixing pipe, and one end of the fixing pipe is fixedly connected with a connector. The traction assembly controls the sliding rod to telescopically move along the fixed pipe; the cutting assembly comprises a cutting knife, an annular cutting plate and an annular blade; the traction assembly and the cutting assembly are arranged, a cutting knife is tightly attached to the surface of fascia, an operator can complete the scraping action by holding a holding handle with one hand, the cutting knife is inserted below the fascia to serve as a supporting base, a stable clamping space is formed by the cutting knife and an annular cutting plate, an annular blade and a cutting groove are accurately cut, it is guaranteed that the fascia is uniform in size, and the damage and perforation risk is reduced; the operation time is shortened, the fine cutting and scraping operation with one hand is realized, and the fascia surface treatment stability is enhanced.
Owner:THE FIRST AFFILIATED HOSPITAL OF XINXIANG MEDICAL UNIVERSITY

Otolaryngology infusion needle handle (2)

ActiveCN310077415SNeurosensory deafnessPhysical therapy
1. The name of the design product: otology infusion needle handle (2). 2. The use of the design product: for the treatment of symptoms such as inner ear administration of neurosensory deafness. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.
Owner:HANGZHOU QIANTANG LONGYUE BIOTECHNOLOGY CO LTD

In-vivo tragus cartilage intercepting device

ActiveCN223615019UEar treatmentReoperative surgeryTragal cartilage
The utility model relates to the technical field of otology surgery, and discloses an in-vivo tragus cartilage intercepting device, the in-vivo tragus cartilage intercepting device comprises a handle assembly and a cutting assembly, the handle assembly comprises a first clamping arm and a second clamping arm, the first clamping arm and the second clamping arm are hinged and can be stressed to get close to each other or get away from each other, and the cutting assembly is connected with the handle assembly. The cutting assembly comprises a cutting ring and a cutting disc, the cutting ring is connected to the end of the first clamping arm, the cutting disc is connected to the end of the second clamping arm, the size of the cutting ring and the size of the cutting disc are adjustable, the cutting ring and the cutting disc are oppositely arranged, and the cutting disc can be clamped into the cutting ring along with mutual approaching of the first clamping arm and the second clamping arm. And the tragus cartilage is cut. The in-vivo tragus cartilage intercepting device can be used for intercepting the required tragus cartilage, so that the waste of the tragus cartilage is reduced, and the tragus form is maintained.
Owner:THE CENTRAL HOSPITAL OF WUHAN (WUHAN NO 2 HOSPITAL WUHAN CANCER RESEARCH INSTITUTE)

Devices, systems, and methods for otology

ActiveCN115515542BEar treatmentCannulasEardrum repairHL - Hearing loss
Systems and methods can be employed to facilitate access and surgery in the external, middle, and inner ear for the diagnosis or treatment of ear conditions including, but not limited to, hearing loss and excess earwax. In some examples, the systems and methods include instruments and techniques that facilitate trans-tympanic or trans-fibroannular access to the middle ear. The systems and methods can also be used to improve the accessibility of various otologic procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair, and ossicular chain repair.
Owner:SPIRAL THERAPEUTICS INC

Postoperative nursing device for otology patient

The utility model provides a postoperative nursing device for otology patients, and belongs to the technical field of otology nursing. The device comprises a main pillow and an auxiliary pillow, a connecting mechanism is arranged between the bottom of the main pillow and the bottom of the auxiliary pillow, a nursing groove is formed in the distance between the main pillow and the auxiliary pillow, a neck pillow is fixed to the side, away from the auxiliary pillow, of the main pillow, and the connecting mechanism comprises a first base plate and a second base plate; the first base plate is fixed to the bottom of the main pillow body, the second base plate is fixed to the bottom of the auxiliary pillow body, and the first base plate and the second base plate are connected in a telescopic mode. The size of the nursing groove and the expansion degree of the neck pillow can be adjusted according to the needs of a patient, use is flexible, the sleep quality of the otology patient can be effectively guaranteed, and the nursing and rehabilitation effect is improved.
Owner:BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Cutter handle for otologic operation

The cutter handle comprises a front bearing seat, a motor shell, a core connecting wire and a plug front sleeve, the motor shell is arranged outside the front bearing seat in a sleeved mode, a motor shaft is arranged inside the front bearing seat in a sleeved mode, a sealing ring is connected to the inner ring of the front bearing seat in a clamped mode, and the core connecting wire is connected with the plug front sleeve in a clamped mode. A single-layer wave pad is attached to one side of the sealing ring, a flat washer is attached to one side of the single-layer wave pad, one end of the front bearing seat abuts against a first bearing, an inner ring of the first bearing is fixedly connected with the motor shaft, and an iron core is fixedly connected to the middle of the interior of the motor shell. The end plug front sleeve of the integral structure and equipment are plugged to complete electrical connection, in the using process, a small motor of a motor shell provides electric drive, a motor shaft is driven to rotate after drive, and then splicing is completed through a cylindrical pin at the end of the motor shaft and an otology surgery cutter, so that use operation of medical staff is achieved.
Owner:CHENGDU LEIHUO TECHNOLOGY CO LTD

Method and device for constructing large model for otology vertical field

This invention discloses a method and apparatus for constructing a large-scale model for the vertical field of otology, relating to the field of artificial intelligence technology. The method includes: acquiring an otology dataset, including at least one of the following: otology pathology reports, otology journal articles, otology clinical practice guidelines, otology pathology images and annotations, ear function testing data, otoscopy videos, surgical operation videos and keyframes and annotations, and a 3D point cloud model of ear structure; pre-training a general basic large-scale model using the otology dataset to obtain a large-scale model with otology professional knowledge; and fine-tuning the pre-trained large-scale model using a fine-tuning instruction dataset to obtain an interactive otology vertical-domain large-scale model, wherein the fine-tuning instruction dataset includes at least one of the following: otology single-turn dialogue data, otology multi-turn dialogue data, otology NLP task instruction data, and clinical operation guidance data. This embodiment can enhance the large-scale model's understanding of otology knowledge.
Owner:HANGZHOU HUIER HEARING INSTR & TECH CO LTD

Visualization devices, systems, and methods for otology and other uses

Devices, systems, and methods can be employed to facilitate indirect viewing into cavities such as, but not limited to, the middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and procedures in the outer, middle, and / or inner ear in order to diagnose and / or treat disorders including, but not limited to, hearing loss and other ear disorders. In particular implementations, a surgical microscope is used in conjunction with an inverter lens and a distal lens. In some cases, the distal lens transverses a membrane or septum such as, but not limited to, the tympanic membrane. The distal lens can be an assembly combining two or more lenses, in some embodiments. For example, in some cases wide angle lenses, zoom lenses, lenses of other various shapes and / or prisms can be used in the distal lens.
Owner:SPIRAL THERAPEUTICS INC

Levofloxacin-based otology liquid and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, and provides a levofloxacin-based liquid for otology and a preparation method thereof, the levofloxacin-based liquid for otology comprises 12-18 mg / ml of levofloxacin, 0.5-1.5 mg / ml of EDTA-2Na, 0.010-0.050 mg / ml of benzalkonium chloride, a pH regulator and purified water, the pH is 6.0-7.0, and the osmotic pressure is 280-340 mOsm / kg. In the preparation process, the EDTA-2Na is dissolved at 40 + / -5 DEG C, the temperature is reduced to 25 + / -3 DEG C, the levofloxacin is added, then the benzalkonium chloride is added, and after the pH is adjusted, the volume is constant, and filtering and filling are carried out. Through metal chelation synergism and accurate pH control, 24-month stability reaches 95% or above, MIC is reduced by 60%-70%, bioavailability is improved to 78.5%, and the antibacterial composition has remarkable antibacterial activity on various ear pathogenic bacteria.
Owner:GUANGZHOU TONGHUI PHARM CO LTD