Traditional medicine composition for treating cardiovascular and cerebrovascular diseases
A cardiovascular and cerebrovascular disease and composition technology, which can be used in cardiovascular system diseases, drug combinations, active ingredients of hydroxyl compounds, etc., can solve problems such as relatives and social burdens, inability to take care of themselves, and achieve controllable quality, easy industrialization, The effect of huge social benefits
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Embodiment 1
[0100] Preparation of Salvia miltiorrhiza extract: Take Danshen decoction pieces or crushed Salvia miltiorrhiza, decoct twice with water, add 6.5 times the weight of the medicinal material each time, 2 hours each time; combine the extracts, adjust the pH to 2 with acid, let cool, filter The resin volume on the filtrate is equivalent to the AB-8 type macroporous resin (produced by Nankai University Resin Factory, Tianjin) column with 3 times of the crude drug, first wash with 1.5 times of column volume water, discard the washing solution, and then use 2.5 times of column volume Elute with 95% ethanol, collect the eluate; concentrate the eluate under reduced pressure until the specific gravity of the extract is 1.15, and dry under reduced pressure to obtain the Danshen extract. The Danshen extract contains 4.5% danshensu, 57.1% total phenolic acid and 27.5% salvianolic acid B.
[0101] Preparation of Panax notoginseng extract: Take notoginseng decoction pieces, crush them, soak ...
Embodiment 2
[0104] Preparation of Salvia miltiorrhiza extract: Take Danshen decoction pieces or crushed Salvia miltiorrhiza, add water and ultrasonically extract 2 times, add water 6 times the weight of the medicinal material for 40 minutes each time; combine the extracts, adjust the pH to 2.5 with acid, let cool, filter The resin volume on the filtrate is equivalent to the D101 type macroporous resin (produced by Nankai University Resin Factory, Tianjin) column of 3 times of the crude drug, first wash with 1.0 times of column volume water, and the washing solution is discarded, and then use 95% of 3 times of column volume Eluted with ethanol, collected the eluate; the eluate was concentrated under reduced pressure until the specific gravity of the extract was 1.15, and dried under reduced pressure to obtain the Danshen extract. The salvia miltiorrhiza extract has a danshensu content of 4.6%, a total phenolic acid content of 54.6%, and a salvianolic acid B content of 26.4%.
[0105] Prepa...
Embodiment 3
[0108] Preparation of Salvia miltiorrhiza extract: Take Danshen decoction pieces or crushed Salvia miltiorrhiza, decoct twice with water, add 6.5 times the weight of the medicinal material each time, 2 hours each time; combine the extracts, adjust the pH to 2 with acid, let cool, filter The resin volume on the filtrate is equivalent to the ZTC type macroporous resin (produced by Tianjin Nankai University Resin Factory) column of 3 times of crude drug, first wash with 1.5 times of column volume water, and the washing solution is discarded, and then use 95% of 2.5 times of column volume Eluted with ethanol, collected the eluate; the eluate was concentrated under reduced pressure until the specific gravity of the extract was 1.12, and dried under reduced pressure to obtain the Danshen extract. The salvianolic acid B content of the salvia miltiorrhiza extract is 4.1%, the total phenolic acid content is 53.6%, and the salvianolic acid B content is 24.8%.
[0109] Preparation of Pan...
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