26 results about "DANSHEN EXTRACT" patented technology

The invention discloses a traditional Chinese medicine ingredient modified bone graft material and a preparation method thereof, and relates to the technical field of bone graft materials. The feed additive is prepared from the following raw materials: calcined bone meal and a traditional Chinese medicine extract, the traditional Chinese medicine extract comprises a radix salviae miltiorrhizae extract and / or a radix scutellariae extract. The preparation method comprises the following steps: preparing calcined bone meal, preparing simulated body fluid and preparing the modified bone graft material. The product material can be applied to a dental bone grafting material. The traditional Chinese medicine extract is loaded on the bone material, and the bone material is modified, so that the bone graft material with good biocompatibility, osteogenesis promoting capability and better osteogenesis induction potential can be obtained.

The present invention relates to a pharmaceutical composition for improving sexual function, comprising a Salvia miltiorrhiza extract as an active ingredient. Specifically, the pharmaceutical composition can improve overall sexual satisfaction through the improvement of one or more selected from the group consisting of erectile function, sexual pleasure, sexual desire, and sexual intercourse satisfaction.

The invention discloses a traditional Chinese medicine composition for improving blood sugar and blood fat and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following components in percentage by mass: 10-22 parts of a ginseng extract, 10-50 parts of a gynostemma pentaphylla extract, 10-40 parts of a radix salviae miltiorrhizae extract and 10-40 parts of a fructus crataegi extract. The traditional Chinese medicine composition is simple in formula, simple and convenient to prepare, reliable in quality control, safe and effective, has double effects of improving blood sugar and blood fat, and has remarkable progress in the aspects of formula legality, raw material availability, process feasibility, quality controllability and efficacy comprehensiveness.

The present application provides a traditional Chinese medicine composition for preventing and treating metabolic-associated fatty liver disease, a capsule, and use. The traditional Chinese medicine composition is prepared from the following starting materials in parts by weight: 1-5 parts of Curcumae Longae Rhizoma extract, 10-20 parts of Puerariae Lobatae Radix extract, 15-30 parts of Salviae Miltiorrhizae Radix et Rhizoma extract, 1-10 parts of Schisandrae Chinensis Fructus extract, and 2-15 parts of Ganoderma extract. The preparation method for the capsule comprises the following steps: mixing the Curcumae Longae Rhizoma extract, the Puerariae Lobatae Radix extract, the Salviae Miltiorrhizae Radix et Rhizoma extract, the Schisandrae Chinensis Fructus extract, the Ganoderma extract, and maltodextrin uniformly, and filling the mixture into a hydroxypropyl methylcellulose hollow capsule to give the capsule. Salviae Miltiorrhizae Radix serves as the sovereign medicinal, Curcumae Longae Rhizoma and Puerariae Lobatae Radix serve as ministerial medicinals, and Schisandrae Chinensis Fructus and Ganoderma serve as adjuvant medicinals, such that the combination of such medicinals achieves the effects of protecting the liver, promoting blood circulation and regulating the flow of qi, promoting the production of body fluids and quenching thirst, tonifying qi for tranquillization, and the like. The present application can effectively prevent and treat metabolic-associated fatty liver disease and can treat non-alcoholic fatty liver disease, especially achieving a significant therapeutic effect on the non-alcoholic simple fatty liver and non-alcoholic steatohepatitis.

The invention discloses a Chinese herbal medicine composition with an effect of relieving plateau exercise fatigue and application thereof, and the Chinese herbal medicine composition is prepared from the following raw materials in parts by weight: 3-27 parts of an acanthopanax senticosus extract, 3-15 parts of a radix salviae miltiorrhizae extract, 5-15 parts of a moringa oleifera leaf extract, 3-15 parts of a radix puerariae extract, 3-10 parts of a turmeric extract and 3-9 parts of an tangerine pith extract. All the extracts are water extracts. The composition can relieve plateau exercise fatigue, improve the hypoxia tolerance, exercise fatigue resistance and oxidative stress resistance of the body, and improve the comprehensive exercise performance of the body.

The invention relates to a composition with a function of improving bone mineral density, application of the composition and a preparation method of related health-care products or foods, and the composition comprises the following components in parts by weight: 0.5-4.5 parts of D-glucosamine hydrochloride, 0.5-3 parts of calcium carbonate, 0.1-1.5 parts of sodium chondroitin sulfate, 0.5-2.5 parts of American ginseng extract, 0.2-2 parts of salvia miltiorrhiza extract, 0.15-1.5 parts of radix paeoniae alba extract and 0.1-1 part of turmeric extract. The composition is prepared into a medicine, a health care product or a food to increase the bone mineral density. According to the composition, green, natural and high-quality raw materials and auxiliary materials are selected, the composition is prepared from the perspective of traditional Chinese medicine, modern nutriology and modern pharmacology, calcium supplement, articular cartilage protection and inflammation relieving are integrated, the formula plays a comprehensive role in increasing the bone mineral density in different links, and the effect of increasing the bone mineral density under the effect of three pipes is achieved. The composition can be prepared into medicines, health-care products or foods, the preparation process is simple, and the prepared product is green, safe and remarkable in curative effect and has a good market prospect.

The invention provides a pharmaceutical composition for treating diabetic foot. The pharmaceutical composition comprises a traditional Chinese medicine active component, a growth factor, an antibacterial and antioxidant component, a microenvironment regulator and other auxiliary materials. The traditional Chinese medicine active components comprise 5-10 parts of a radix salviae miltiorrhizae extract, 3-8 parts of astragalus polysaccharide, 2-5 parts of dragon's blood and 1-3 parts of radix stemonae powder; the antibacterial and antioxidant components comprise 2 to 6 parts of chitosan, 0.1 to 0.5 part of nano-silver particles and 0.5 to 2 parts of vitamin E; 0.01 to 0.1 part of a growth factor; the microenvironment conditioning agent is prepared from hyaluronic acid and lactic acid according to the mass ratio of (0.1 to 0.5) to (0.05 to 0.3); the other auxiliary materials comprise 30 to 50 parts of chitosan composite hydrogel and 5 to 10 parts of glycerol. According to the invention, the traditional Chinese medicine active components are combined with the drug-loaded hydrogel to form the pharmaceutical composition with antibacterial, antioxidant and tissue regeneration promotion functions, and the pharmaceutical composition can be used for treating diabetic foot and has a good clinical application prospect.

The invention discloses a liver-protecting kudzu vine root composition and a preparation method and application thereof in the field of medicinal chemistry, and the liver-protecting kudzu vine root composition comprises a kudzu vine root extract, silymarin, a salvia miltiorrhiza extract, vitamins and two traditional Chinese medicine modified raw materials, the two modified raw materials are respectively an ester derivative formed by puerarin and aminobutyric acid and an ester derivative formed by glycyrrhizic acid and aminocaproic acid. The preparation method comprises the following steps: pre-mixing the extracts and the vitamins, adding the two modified raw materials, uniformly mixing, finally adding the pharmaceutic adjuvants, and tabletting and forming. The two modified raw materials are respectively prepared by activating puerarin or glycyrrhizic acid and corresponding aminocarboxylic acid under the action of a specific condensation reagent, condensing and purifying. According to the composition disclosed by the invention, two structurally modified active components are innovatively introduced and have a synergistic effect with a plurality of liver protection raw materials, so that the anti-oxidation, anti-inflammatory and liver protection effects are remarkably enhanced, and the composition can be used for preparing medicines or health-care products for preventing and treating alcoholic liver injury and non-alcoholic fatty liver diseases.

The invention belongs to the technical field of biological medicines, and particularly relates to a traditional Chinese medicine composition for treating orthopedic soft tissue injury and a preparation method thereof. The composition comprises the following raw materials in parts by weight: 4-6 parts of centella asiatica extract, 4-6 parts of salvia miltiorrhiza extract, 4-6 parts of pseudo-ginseng extract, 2-3.5 parts of eucommia ulmoides extract, 2-4 parts of liquorice extract, 4-7 parts of frankincense resin extract, 4-6.5 parts of turmeric extract and 3-4.5 parts of ligusticum wallichii extract. According to the invention, breakthrough is realized through prescription-drug delivery system-process triple synergy, and in prescription, the eight traditional Chinese medicine extracts are in multi-target synergy, and the whole process of anti-inflammation, analgesia and repair promotion is covered. On the delivery system, the hydrophilic component is included by cyclodextrin to be solubilized and stable, and the lipophilic component is efficiently transdermally loaded in the temperature-sensitive gel in the form of nanoemulsion to form a long-acting drug delivery bin on the skin. According to the process, microscopic uniformity and macroscopic stability of the system are ensured through precise low-temperature swelling, split-phase treatment and vacuum integration.

The invention provides a probiotic fermentation composition capable of improving athletic performance and a preparation method of the probiotic fermentation composition, and belongs to the field of non-alcoholic beverages. The composition comprises the following components: a fermented red ginseng extract, a fermented radix astragali extract, a radix rehmanniae preparata extract, a radix salviae miltiorrhizae extract, a rhizoma chuanxiong extract, donkey-hide gelatin and a black tea extract. The composition prepared by a specific probiotic fermentation process has the following beneficial effects: firstly, through a multi-target synergistic effect, the motor function is systematically improved, including enhancing endurance, accelerating fatigue recovery and relieving motor-induced oxidative stress injury; 2, improving body energy metabolism and blood circulation, and promoting muscle protein synthesis and repair; thirdly, a process of firstly fermenting and then extracting is adopted, so that the bioavailability of active ingredients is remarkably improved, and the product is pure and safe; and 4, the preparation process is stable and controllable, and is suitable for physical maintenance and function improvement requirements of various groups such as athletes, middle-aged and elderly people, rehabilitation people and the like.

The application belongs to the technical field of medicine preparation, and particularly relates to an Nrf2 activator and application thereof in preparation of medicine. The Nrf2 activator comprises a compound I and a traditional Chinese medicine extract; a mass ratio of the compound I to the traditional Chinese medicine extract is 1-10:0.5-5; the traditional Chinese medicine extract is one or more of an astragalus extract, a radix ginseng extract, a radix salviae miltiorrhizae extract and a radix smilacae extract. The Nrf2 activator is prepared into medicine for preventing or treating diabetic nephropathy together with a pharmaceutically acceptable carrier or excipient. The Nrf2 activator can target and activate an Nrf2 signal pathway, significantly inhibit accumulation of collagen and oxidative stress, and prevent and treat diabetic nephropathy.

The invention relates to a nasal spray for prevention and adjuvant therapy of cognitive impairment and a preparation method thereof, and belongs to the field of health-care medicines. The formula of the nasal spray for prevention and adjuvant treatment of cognitive impairment comprises the following components in percentage by volume: a solvent the balance of water; 2%-5% of butanediol; 2%-5% of glycerin; active components: 0.01%-0.1% of a bay leaf extract; 0.01% to 0.1% of a bacopa monnieri extract; 0.01%-0.05% of a radix salviae miltiorrhizae extract; the efficient penetration enhancing and feeling adjusting components comprise 0.001%-0.1% of xanthoxylin and 0.001%-0.01% of eucalyptus globulus leaf oil; 0.001% to 0.01% of menthol; the nasal spray prepared by the invention is a composite plant extract nasal spray which is safe, effective and convenient to use, has a multi-target synergistic effect and has high brain-targeted delivery efficiency.

The invention discloses a wet tissue for fading face acne marks and a preparation method thereof, and belongs to the field of personal care supplies, the wet tissue comprises a wet tissue piece, a face care solution infiltrated in the wet tissue piece, and a package for accommodating the wet tissue piece; the facial care solution comprises a basic material A and an auxiliary material B, nicotinamide, tranexamic acid, a moisturizing, repairing and relieving component, a salvia miltiorrhiza extract and the like are added into the base material A and the auxiliary material B, all the components are compatible, the effects are complemented and linked, the synergistic gain effect is achieved, and meanwhile the excellent moisturizing, repairing, relieving, anti-inflammatory and antibacterial effects are achieved. The wet tissue product is free of acute skin irritation, good in tolerance to sensitive skin, free of damage to skin barriers, continuous and stable in effect after long-term use and capable of being widely applied to daily nursing of face acne marks.

The present application provides a fluffy oil-control anti-dandruff composition, a preparation method and application thereof, and relates to the technical field of cosmetics. The fluffy oil-control anti-dandruff composition comprises a plant composition and an anti-dandruff composition, wherein the plant composition is composed of Capra hircus, Terminalia chebula, flower / leaf of Tamarix and Artemisia annua in a mass ratio of (1-20):20:1:10, has the effects of synergistically inhibiting Malassezia and inhibiting hyaluronidase activity; the anti-dandruff composition comprises at least one of piroctone olamine, white willow bark and salvia miltiorrhiza extract, and is used for enhancing the effects of inhibiting bacteria, controlling oil and relieving. The fluffy oil-control anti-dandruff composition can simultaneously regulate the microecological balance of the scalp, and improve the problems of dandruff, excessive oil and scalp itching caused by sensitive scalp, and can be widely used in the preparation process of products for improving dandruff, excessive oil and scalp itching caused by sensitive scalp.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a composition for assisting in protecting chemical liver injury and gastric mucosal injury as well as a preparation method and a product of the composition. The composition is prepared from the following components in parts by weight: 35 to 45 parts of radix puerariae extract, 25 to 35 parts of semen hoveniae extract, 25 to 35 parts of radix codonopsis extract, 28 to 33 parts of radix salviae miltiorrhizae extract and 25 to 35 parts of rhizoma atractylodis macrocephalae extract. The composition has a comprehensive treatment effect on alcoholic liver injury and gastric mucosal injury by synergistically regulating lipid metabolism, oxidative stress, inflammatory response and cell signal pathways. According to the technical scheme provided by the invention, comprehensive protection on alcoholic liver injury and gastric mucosal injury is realized through multi-channel cooperative regulation and control, and the defects of single target spot and limited curative effect of the existing therapeutic drug are overcome. The technical scheme provides a safe and effective intervention measure for digestive system injury caused by alcohol, and has a wide application prospect in the field of health-care product and medicine development.

The invention relates to the technical field of biological medicine manufacturing, in particular to a traditional Chinese medicine compound gel containing bioactive organic components and capable of synergistically repairing hypertrophic scars based on four-season qi and a preparation method of the traditional Chinese medicine compound gel. The compound gel is formed by mixing a bottle A base matrix and a bottle B four-season additive according to the ratio of 9: 1, the base substrate of the bottle A contains various bioactive organic components such as a salvia miltiorrhiza extract, asiatic acid, bioactive hirudin, perilla oil and the like; according to the four-season additive in the bottle B, corresponding traditional Chinese medicine extracts are selected according to seasons, the preparation method adopts a biotechnology process including supercritical COextraction, a biocompatibility nanometer co-grinding technology and other modern biotechnologies, the transdermal absorption rate of mineral components is remarkably increased, the anti-fibrosis effect is enhanced through a hirudin-perilla oil soluble synergistic system, and the anti-fibrosis effect is improved. The four-season differentiated formula realizes accurate repair of preventing wind evil in spring, clearing blood heat in summer, moistening dryness injury in autumn and dredging collaterals in winter.

The invention relates to the technical field of pig feed, in particular to improved compound feed capable of reducing mutton smell of pork and a preparation method of the improved compound feed. The feed comprises a feed additive with the function of reducing the mutton smell of pork, and the feed additive comprises fructo-oligosaccharide, phytosterol and a salvia miltiorrhiza extract. Through the effects of the fructo-oligosaccharide, the phytosterol and the radix salviae miltiorrhizae extract, the whole-course blocking of chains generated by goaty-flavor substances is realized, and the contents of skatole and androsteneone in fat are remarkably reduced. While the mutton smell is effectively removed, the scheme has no negative influence on the pork quality, and can obviously reduce the drip loss, improve the water holding capacity, reduce the shearing force and improve the red degree of the meat color.

This invention discloses a traditional Chinese medicine composition for treating non-alcoholic fatty liver disease (NAFLD). The composition is made from the following raw materials in parts by weight: 12 parts turmeric extract, 9 parts rhubarb extract, 10 parts atractylodes macrocephala extract, 10 parts gynostemma pentaphyllum extract, 10 parts kudzu root extract, 10 parts lotus leaf extract, 10 parts alisma plantago-aquatica extract, 10 parts salvia miltiorrhiza extract, 15 parts polygonum cuspidatum extract, 10 parts silkworm extract, 3 parts leech extract, 10 parts malachite extract, and 6 parts licorice extract; as well as its preparation method and uses. This composition can effectively alleviate the clinical symptoms of NAFLD patients, improve liver function, reduce the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), and triglycerides (TG), total cholesterol (TC), and low-density lipoprotein (LDL-C) in the blood, and increase the level of high-density lipoprotein (HDL-C), effectively improving blood lipids and alleviating the protracted disease progression towards recovery.

The invention relates to a hair care liquid for promoting locking of hair cuticles and a preparation method thereof, and belongs to the field of hair cuticle care, and the hair care liquid comprises the following substances in parts by weight: 1.2-1.6 parts of keratin, 1.3-1.5 parts of vitamin E, 0.2-0.4 part of lysine, 1.3-1.5 parts of ceramide, 0.2-0.4 part of a camellia extract, 0.2-0.4 part of a salvia miltiorrhiza extract, 0.2-0.4 part of an angelica sinensis extract, 4.2-4.6 parts of nano-liposome and 3.5-3.9 parts of stearic acid. 11.3 to 11.9 parts of glycerol and 57 to 60 parts of purified water. According to the invention, nutrient substances such as keratin, vitamin, lysine and ceramide for repairing and locking hair cuticles are packaged by nano-liposome; therefore, the encapsulated nutrient substances can be stably and quickly conveyed to gaps of hair cuticles in a targeted manner and released, so that the repairing and locking efficiency of the hair cuticles is improved.

The invention relates to application of a composition in preparation of a product helpful for regulating intestinal flora. The composition consists of 170 parts by weight of pseudo-ginseng superfine powder, 75 parts by weight of an astragalus extract, 55 parts by weight of a salvia extract, 30 parts by weight of a ginkgo leaf extract, 30 parts by weight of a kudzuvine root extract, 20 parts by weight of an emblic leafflower fruit extract and 20 parts by weight of a polygonatum odoratum extract. According to the composition disclosed by the invention, the components are reasonably proportioned, and tests prove that the relative abundance of beneficial bacteria can be remarkably increased, and the relative abundance of harmful bacteria can be reduced. Therefore, the traditional Chinese medicine composition provided by the invention is beneficial to regulating the intestinal flora, so that the structure of the intestinal flora is close to normal.

The invention discloses pure traditional Chinese medicine compound oil with antioxidant and bacteriostatic effects and a preparation method of the pure traditional Chinese medicine compound oil. The pure traditional Chinese medicine compound oil comprises the following raw material components in percentage by weight: 10-20% of a radix salviae miltiorrhizae extract; 8-15% of a michelia alba extract; 8-15% of cinnamon oil; 8-15% of galangal oil; 3-8% of litsea cubeba oil; 5%-10% of zedoary turmeric oil; 1-5% of peppermint oil; and the balance tea oil. The pure traditional Chinese medicine compound oil is prepared by compounding a plurality of natural plant extracts, the preparation method is simple, green and safe, and the adopted raw material components are reasonably matched and cooperate with one another to play the anti-oxidation and antibacterial effects. The pure traditional Chinese medicine compound oil has strong bacteriostatic, anti-inflammatory and anti-oxidation effects, can effectively scavenge free radicals and reduce free radical damage, and can effectively inhibit bacterial breeding, prevent inflammatory infection, relieve and protect skin and enhance the anti-oxidation, bacteriostatic and anti-inflammatory capacities of the skin. The pure traditional Chinese medicine compound oil can be further used for preparing cosmetics and daily chemical products with antioxidant and bacteriostatic effects.

The invention relates to the technical field of traditional Chinese medicine microneedle application, and discloses a microneedle body, a preparation method of the microneedle body, microneedle application and application of the microneedle application. The microneedle body comprises a needle tip, a separation layer and a substrate layer which are arranged in sequence, a material I for forming the needle tip comprises silver-loaded oxidized chitosan and a traditional Chinese medicine composition; a material II for forming the separation layer comprises a component A and magnesium particles; a material III for forming the substrate layer comprises silver-loaded oxidized chitosan; the traditional Chinese medicine composition contains an angelica sinensis extract, a prepared rehmannia root extract, a ligusticum wallichii extract, a radix paeoniae alba extract, peach kernel powder, a safflower extract, a rhizoma cyperi extract, a salvia miltiorrhiza extract and glycyrrhizic acid in a mass ratio of 1: (0.3-3): (0.3-3): (0.3-3): (0.2-3): (0.2-3): (0.2-3): (0.3-3): (0.3-2). The microneedle body has a good application prospect in preparation of an application for treating irregular menstruation caused by qi stagnation and blood stasis.

To provide an antitumor agent, a pharmaceutical composition and a composition for antitumor having high antitumor action with a small amount, high safety to the human body and a wide application range to a composition having a fragrance component.SOLUTION: There are provided an anti-tumor agent containing an odorous Magnolia Kobus extract component, the anti-tumor agent containing citral or 1, 8-cineole, the anti-tumor agent in which the odorous Magnolia Kobus extract component is an odorous Magnolia Kobus essential oil or an extract thereof, the anti-tumor agent for treating breast, colon, pancreatic, esophageal or gastric cancers, and a pharmaceutical composition and an anti-tumor composition containing the same.SELECTED DRAWING: None

This invention discloses a traditional Chinese medicine skin barrier repair agent, comprising: Salvia miltiorrhiza extract, Portulaca oleracea extract, Centella asiatica extract, and Astragalus membranaceus extract in a weight ratio of (2-3):(2.5-3.5):(1.8-2.4):(3-4); wherein the solid content of the Salvia miltiorrhiza extract in the Salvia miltiorrhiza extract is 0.1%-0.4%; the solid content of the Portulaca oleracea extract in the Portulaca oleracea extract is 1.1%-1.5%; the solid content of the Centella asiatica extract in the Centella asiatica extract is 14.0%-17.0%; and the solid content of the Astragalus membranaceus extract in the Astragalus membranaceus extract is 1.1%-1.5%. This traditional Chinese medicine skin barrier repair agent can soothe and repair the skin, and can be applied to repair creams to repair cells, promote cell metabolism and renewal, have anti-inflammatory and antibacterial effects, and soothe and strengthen the skin, achieving comprehensive skin repair.

This invention discloses a compound traditional Chinese medicine eczema ointment and its preparation method, relating to the field of traditional Chinese medicine technology. The compound traditional Chinese medicine eczema ointment comprises the following components by weight: 5-15 parts of Acorus tatarinowii extract, 5-10 parts of Terminalia chebula extract, 5-10 parts of Gynostemma pentaphyllum extract, 5-15 parts of Paeonia lactiflora extract, 5-15 parts of Salvia miltiorrhiza extract, 1-10 parts of Allium macrostemon extract, 5-15 parts of Dictamnus dasycarpus root bark extract, 5-10 parts of Pueraria lobata extract, 5-10 parts of Astragalus membranaceus extract, 10-20 parts of Hedyotis diffusa extract, 0.1-1 part of borneol, and 300-600 parts of cream base. The compound traditional Chinese medicine eczema ointment prepared by this invention exhibits excellent antibacterial properties and stability.

This invention provides a Naoluotong capsule and its preparation method, belonging to the field of pharmaceutical technology. The Naoluotong capsule comprises the following components in parts by weight: 40-60 parts of Salvia miltiorrhiza extract, 40-60 parts of Ligusticum chuanxiong extract, 40-60 parts of Astragalus membranaceus extract, 40-60 parts of tolperidone hydrochloride, 5-15 parts of methyl hesperidin, 1-4 parts of vitamin B6, 12-25 parts of polyvinylpyrrolidone K30, 13-25 parts of polyethylene glycol 400, 32-42 parts of corn starch, 3-7 parts of magnesium stearate, and 200-250 parts of an ethanol aqueous solution with a volume concentration of 70-80%. The Naoluotong capsule prepared by this invention has a short disintegration time, good stability, and a high tolperidone hydrochloride content.