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43 results about "DANSHEN EXTRACT" patented technology

Nano-scale repairing composition, nano-scale repairing cosmetic and preparation method and application of nano-scale repairing composition and nano-scale repairing cosmetic

The invention relates to the technical field of cosmetics, in particular to a nanoscale repair composition, a nanoscale repair cosmetic and a preparation method and application of the nanoscale repair composition and the nanoscale repair cosmetic. The invention discloses a nanoscale repairing composition. The traditional Chinese medicine composition is prepared from the following raw material components in parts by weight: 4 to 6 parts of herba centellae extract, 2 to 4 parts of chamomile extract, 2 to 4 parts of radix ginseng extract, 1 to 3 parts of rhizoma curcumae longae extract, 3 to 5 parts of aloe extract, 1 to 3 parts of oat extract, 1 to 2 parts of liquorice root extract, 0.3 to 0.7 part of green tea extract, 0.5 to 1.5 parts of radix salviae miltiorrhizae extract, 0.5 to 1.5 parts of radix angelicae sinensis extract and 0.5 to 1.5 parts of ganoderma atrum extract. , 0.5 to 1.5 parts of radix astragali seu hedysari extract, 0.3 to 0.7 part of rhizoma polygoni cuspidati extract, and 0.3 to 0.7 part of onion extract. The nanoscale repairing composition and the nanoscale repairing cosmetic disclosed by the invention can improve the moisture content of skin, reduce moisture loss and redness of the skin, accelerate healing of injured skin, effectively relieve inflammatory response and promote collagen regeneration of the skin.
Owner:GUANGDONG PHARMA UNIV

Levocarnitine injection and preparation device thereof

The invention relates to the technical field of levocarnitine injection preparation devices, in particular to a levocarnitine injection and a preparation device thereof. Comprising the following raw materials in percentage by mass: 18%-22% of levocarnitine, 5%-10% of a vitamin antioxidant, 28%-33% of a traditional Chinese medicine extract, a pH regulator and the balance of water for injection, the traditional Chinese medicine composition is prepared from the following components in percentage by mass: 10% of ginseng extract, 10% of fructus lycii extract, 20% of radix astragali extract, 10% of radix salviae miltiorrhizae extract, 8% of fructus schisandrae chinensis extract, 14% of radix notoginseng extract and the balance of pure water. Through combined use of levocarnitine and traditional Chinese medicines, it is found that mixed injection of levocarnitine, the vitamin antioxidant and the traditional Chinese medicine extract has a better treatment effect than independent injection, and the mixed injection shows a more remarkable synergistic effect.
Owner:ZHEJIANG CHANGDIAN PHARM TECH DEV CO LTD

Traditional Chinese medicine ingredient modified bone graft material and preparation method thereof

PendingCN121570649ATissue regenerationProsthesisDANSHEN EXTRACTBone formation
The invention discloses a traditional Chinese medicine ingredient modified bone graft material and a preparation method thereof, and relates to the technical field of bone graft materials. The feed additive is prepared from the following raw materials: calcined bone meal and a traditional Chinese medicine extract, the traditional Chinese medicine extract comprises a radix salviae miltiorrhizae extract and / or a radix scutellariae extract. The preparation method comprises the following steps: preparing calcined bone meal, preparing simulated body fluid and preparing the modified bone graft material. The product material can be applied to a dental bone grafting material. The traditional Chinese medicine extract is loaded on the bone material, and the bone material is modified, so that the bone graft material with good biocompatibility, osteogenesis promoting capability and better osteogenesis induction potential can be obtained.
Owner:SICHUAN UNIV

Composition for improving sexual function comprising salvia miltiorrhiza extract as active ingredient

PCT designated stageWO2026079671A1Natural extract food ingredientsSexual disorderSexual functionErectile function
The present invention relates to a pharmaceutical composition for improving sexual function, comprising a Salvia miltiorrhiza extract as an active ingredient. Specifically, the pharmaceutical composition can improve overall sexual satisfaction through the improvement of one or more selected from the group consisting of erectile function, sexual pleasure, sexual desire, and sexual intercourse satisfaction.
Owner:CUROME BIOSCIENCES CO LTD

Traditional Chinese medicine external nursing medicine for treating burns and scalds

The invention discloses a traditional Chinese medicine external nursing medicine for treating burns and scalds. The traditional Chinese medicine external nursing medicine comprises the following raw material medicines and auxiliary materials in parts by weight, raw material medicines: 8-12 parts of dandelion, 6-8 parts of oldenlandia diffusa, 8-10 parts of purpleflower holly leaf, 8-10 parts of Chinese elm bark, 10-12 parts of calcined dragon bone, 6-8 parts of aloe, 8-10 parts of safflower, 8-10 parts of radix angelicae, 8-10 parts of astragalus membranaceus, 3-5 parts of borneol, 2-4 parts of pearl powder, 1-3 parts of a salvia miltiorrhiza extract, 8-10 parts of golden cypress, 6-8 parts of sanguisorba officinalis and 4-6 parts of rheum officinale; auxiliary materials: 5-10 parts of chitosan, 3-6 parts of hyaluronic acid, 10-20 parts of olive oil and 1-2 parts of nano titanium dioxide; the pearl powder, the radix salviae miltiorrhizae extract, the cortex phellodendri, the radix sanguisorbae and the radix et rhizoma rhei are added to construct an anti-infection-healing promoting-scar inhibiting triple-effect synergistic system, and pharmacodynamic experiments prove that the deep II-degree wound healing time can be shortened by 3-5 days, and the scar hyperplasia degree can be reduced by 40%; the temperature-sensitive hydrogel realizes'gelation when being contacted with skin ', is uniformly coated and is not easy to fall off.
Owner:MEIZHOU JINFANG MEDICAL TECH CO LTD

Naoluotong capsule and preparation method thereof

The invention provides a Naoluotong capsule and a preparation method thereof, and belongs to the technical field of medicines. The Naoluotong capsule is prepared from the following components in parts by weight: 40 to 60 parts of radix salviae miltiorrhizae extract, 40 to 60 parts of rhizoma chuanxiong extract, 40 to 60 parts of radix astragali seu hedysari extract, 40 to 60 parts of tolperidone hydrochloride, 5 to 15 parts of methyl hesperidin, 1 to 4 parts of vitamin B6, 12 to 25 parts of polyvinylpyrrolidone K30, 13 to 25 parts of polyethylene glycol 400, 32 to 42 parts of corn starch, 3 to 7 parts of magnesium stearate and 200 to 250 parts of ethanol aqueous solution with the volume concentration of 70 to 80 percent. The Naoluotong capsule prepared by the invention is short in disintegration time, good in stability and high in tolperidone hydrochloride content.
Owner:GUANGDONG YILI LUODING PHARMA

Whitening and freckle removing formula as well as preparation process and application thereof

PendingCN119792158ACosmetic preparationsToilet preparationsBiotechnologyAdditive ingredient
The invention discloses a whitening and freckle-removing formula as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The formula comprises the following components in percentage by mass: 1.200% of asiaticoside, 0.008%-0.16% of a radix paeoniae alba extract, 0.064%-0.128% of a radix salviae miltiorrhizae extract and 0.016%-0.032% of a honeysuckle flower extract. The asiaticoside, the radix salviae miltiorrhizae extract, the radix paeoniae alba extract and the honeysuckle flower extract are used as traditional Chinese medicine addition components, the proper addition amount of carbomer 940, glycerol and sodium hyaluronate is obtained by utilizing a single-factor experiment, and the matrix proportion of the mask is determined by combining an orthogonal experiment; the addition amount of the traditional Chinese medicine components is determined according to the tyrosinase activity inhibition ratio, and the mask formula is optimized. The'Qing, grass, silver and snow 'mask has good whitening and freckle removing effects, the tyrosinase activity inhibition rate is at least 85.12%, the DPPH free radical scavenging rate is at least 89.15%, and the moisturizing rate is at least 47.93%.
Owner:JIANGSU FOOD & PHARMA SCI COLLEGE

Traditional Chinese medicine blusher and preparation process thereof

The invention discloses a group of traditional Chinese medicine blusher and a preparation process thereof. The invention belongs to the field of cosmetics, and particularly relates to a group of traditional Chinese medicine blusher and a preparation process thereof. The invention provides a composition for brightening skin color. The composition comprises a traditional Chinese medicine extract composition, a matrix and dry powder, the traditional Chinese medicine extract composition contains a lithospermum extract, a salvia extract and a rose extract. Wherein the mass ratio of the radix arnebiae seu lithospermi extract to the radix salviae miltiorrhizae extract to the rose extract is (4-8): 1: 1. According to the blusher with the traditional Chinese medicine extract as the color source and the preparation technology of the blusher, natural medicinal materials such as radix arnebiae seu lithospermi, radix salviae miltiorrhizae and roses serve as core raw materials, related components are extracted through the technology combining hot dipping and cold dipping, the natural and healthy characteristics of traditional Chinese medicine are creatively combined with the function of cosmetics, and the blusher has application prospects.
Owner:XINJIANG XINQIKANG TRADITIONAL CHINESE MEDICINE AGRICULTURAL TECHNOLOGY CO LTD

Traditional Chinese medicine composition for improving blood sugar and blood fat and preparation method thereof

PendingCN121243268AMetabolism disorderPill deliveryDANSHEN EXTRACTGINSENG EXTRACT
The invention discloses a traditional Chinese medicine composition for improving blood sugar and blood fat and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following components in percentage by mass: 10-22 parts of a ginseng extract, 10-50 parts of a gynostemma pentaphylla extract, 10-40 parts of a radix salviae miltiorrhizae extract and 10-40 parts of a fructus crataegi extract. The traditional Chinese medicine composition is simple in formula, simple and convenient to prepare, reliable in quality control, safe and effective, has double effects of improving blood sugar and blood fat, and has remarkable progress in the aspects of formula legality, raw material availability, process feasibility, quality controllability and efficacy comprehensiveness.
Owner:JING BRAND +1

Traditional chinese medicine composition for preventing and treating metabolic-associated fatty liver disease, capsule, and use

PCT designated stageWO2026137640A1DANSHEN EXTRACTCurcuma longa extract
The present application provides a traditional Chinese medicine composition for preventing and treating metabolic-associated fatty liver disease, a capsule, and use. The traditional Chinese medicine composition is prepared from the following starting materials in parts by weight: 1-5 parts of Curcumae Longae Rhizoma extract, 10-20 parts of Puerariae Lobatae Radix extract, 15-30 parts of Salviae Miltiorrhizae Radix et Rhizoma extract, 1-10 parts of Schisandrae Chinensis Fructus extract, and 2-15 parts of Ganoderma extract. The preparation method for the capsule comprises the following steps: mixing the Curcumae Longae Rhizoma extract, the Puerariae Lobatae Radix extract, the Salviae Miltiorrhizae Radix et Rhizoma extract, the Schisandrae Chinensis Fructus extract, the Ganoderma extract, and maltodextrin uniformly, and filling the mixture into a hydroxypropyl methylcellulose hollow capsule to give the capsule. Salviae Miltiorrhizae Radix serves as the sovereign medicinal, Curcumae Longae Rhizoma and Puerariae Lobatae Radix serve as ministerial medicinals, and Schisandrae Chinensis Fructus and Ganoderma serve as adjuvant medicinals, such that the combination of such medicinals achieves the effects of protecting the liver, promoting blood circulation and regulating the flow of qi, promoting the production of body fluids and quenching thirst, tonifying qi for tranquillization, and the like. The present application can effectively prevent and treat metabolic-associated fatty liver disease and can treat non-alcoholic fatty liver disease, especially achieving a significant therapeutic effect on the non-alcoholic simple fatty liver and non-alcoholic steatohepatitis.
Owner:BEIJING TONG REN TANG CHINESE MEDICINE CO LTD +1

A composition for treating rheumatoid arthritis

The invention provides a composition for treating rheumatoid arthritis, belonging to the technical field of traditional Chinese medicine preparations. Strychnine (from Strychnos nux vomica or Strychnos nux vomica extract), atractylodes lactone III (from Atractylodes macrocephala or Atractylodes macrocephala extract), tanshinone IIA (from Salvia miltiorrhiza or Salvia miltiorrhiza extract) and ligusticolide A (from Chuanxiong or Chuanxiong extract) are selected and compounded in a suitable ratio to achieve a good therapeutic effect on rheumatoid arthritis. The invention can achieve more accurate medication by accurately controlling the ratio of each effective ingredient, thereby ensuring the therapeutic effect, reducing the side effects that may be caused by excessive ingredients, and improving the safety of the drug and the tolerance of patients.
Owner:TIANJIN PHARM DA REN TANG GRP CORP LTD TRADITIONAL CHINESE MEDICINE RES INST +2

Pure traditional Chinese medicine compound toning lipstick and preparation process thereof

PendingCN120241570ACosmetic preparationsMake-upDANSHEN EXTRACTColor changes
The invention discloses a pure traditional Chinese medicine compound toning lipstick and a preparation process thereof. The invention belongs to the technical field of biology, and particularly relates to a pure traditional Chinese medicine compound toning lipstick and a preparation process thereof. The invention relates to a composition containing a traditional Chinese medicine toning component. The composition comprises a traditional Chinese medicine extract combination, a matrix, a lubricant and a humectant, the traditional Chinese medicine extract composition comprises a radix arnebiae seu lithospermi extract and other component extracts, and the other component extracts comprise one or more of a radix salviae miltiorrhizae extract and a radix rubiae extract. The obtained traditional Chinese medicine compound toning lipstick is high in color saturation and wide in color variable range and has application value.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI

Chinese herbal medicine composition with function of relieving plateau exercise fatigue and application of Chinese herbal medicine composition

The invention discloses a Chinese herbal medicine composition with an effect of relieving plateau exercise fatigue and application thereof, and the Chinese herbal medicine composition is prepared from the following raw materials in parts by weight: 3-27 parts of an acanthopanax senticosus extract, 3-15 parts of a radix salviae miltiorrhizae extract, 5-15 parts of a moringa oleifera leaf extract, 3-15 parts of a radix puerariae extract, 3-10 parts of a turmeric extract and 3-9 parts of an tangerine pith extract. All the extracts are water extracts. The composition can relieve plateau exercise fatigue, improve the hypoxia tolerance, exercise fatigue resistance and oxidative stress resistance of the body, and improve the comprehensive exercise performance of the body.
Owner:JIANGNAN UNIV

Composition with function of improving bone mineral density, application of composition and preparation method of related health-care products or food

PendingCN121971567ARaw materials are natural and greeneasy to useOrganic active ingredientsConfectioneryBiotechnologyFormulary
The invention relates to a composition with a function of improving bone mineral density, application of the composition and a preparation method of related health-care products or foods, and the composition comprises the following components in parts by weight: 0.5-4.5 parts of D-glucosamine hydrochloride, 0.5-3 parts of calcium carbonate, 0.1-1.5 parts of sodium chondroitin sulfate, 0.5-2.5 parts of American ginseng extract, 0.2-2 parts of salvia miltiorrhiza extract, 0.15-1.5 parts of radix paeoniae alba extract and 0.1-1 part of turmeric extract. The composition is prepared into a medicine, a health care product or a food to increase the bone mineral density. According to the composition, green, natural and high-quality raw materials and auxiliary materials are selected, the composition is prepared from the perspective of traditional Chinese medicine, modern nutriology and modern pharmacology, calcium supplement, articular cartilage protection and inflammation relieving are integrated, the formula plays a comprehensive role in increasing the bone mineral density in different links, and the effect of increasing the bone mineral density under the effect of three pipes is achieved. The composition can be prepared into medicines, health-care products or foods, the preparation process is simple, and the prepared product is green, safe and remarkable in curative effect and has a good market prospect.
Owner:NINGBO TRADITIONAL CHINESE PHARM CORP

Ganoderma lucidum spore powder composition capable of reducing blood fat and preparation method of ganoderma lucidum spore powder composition

InactiveCN119770546AMetabolism disorderPlant ingredientsDANSHEN EXTRACTForsythia
The invention provides a blood fat reducing ganoderma lucidum spore powder composition and a preparation method thereof. The composition comprises ganoderma lucidum spore powder, a salvia miltiorrhiza extract, a fructus forsythiae extract and a licorice extract. In the composition, the ganoderma lucidum spore powder and the traditional Chinese medicine extract are reasonably utilized, so that the obtained composition has an excellent lipid-lowering effect; and the composition has the advantage of few adverse reactions.
Owner:SHANDONG ZHIRENTANG PHARM CO LTD

A high mountain plant composition for nourishing skin, preventing hair loss and strengthening hair, its essence and preparation method

The present invention discloses a high mountain plant composition for nourishing skin, preventing hair loss and strengthening hair, and an essence thereof, and a preparation method thereof, aiming to provide a high mountain plant composition for nourishing and repairing the head skin, reducing hair loss, and hair care, and an essence thereof; the technical solution includes: 6.25-35% of Salvia miltiorrhiza Bunge extract, 3.75-15% of Lamium album L. flower extract, 12-36% of Eclipta prostrata L. leaf extract, 8%-24% of Platycladus orientalis (L.) Franco leaf extract, and 30%-70% of Gentiana scabra Bunge root extract; it belongs to the daily chemical technology field.
Owner:GUANGZHOU ZHONGTONG BIOCHEMICAL PROD CO LTD

Salvia miltiorrhiza extract extraction equipment

The utility model relates to the field of medicine extraction, in particular to salvia miltiorrhiza extract extraction equipment, and aims to solve the technical problems that when an ethanol reflux method is applied, extraction can be accelerated under the assistance of vibration, but extraction sealing is difficult to guarantee during vibration. The lower end of the sealing hopper is connected with a second elastic rubber mat, the first elastic rubber mat and the second elastic rubber mat are connected with a top cover, the top cover can be locked to the upper portion of the extraction chamber, and one-way valves are arranged in the air outlet pipeline and the backflow pipeline. The air outlet pipeline and the backflow pipeline are respectively communicated with an air inlet pipe and a backflow pipe of the condensation system through corrugated hoses, the extraction kettle is connected with the vibration mechanism, the top cover provides support for the sealing hopper through two elastic rubber pads, vibration is not influenced by support, and the air outlet pipeline and the backflow pipeline are connected with the condensation system through corrugated hoses. Sealing is guaranteed, and meanwhile vibration cannot be transmitted to a condensation system.
Owner:DAXINGANLING TIANCAO PHARM CO LTD

New application of sagittaria sagittifolia extract, traditional Chinese medicine composition and preparation method of traditional Chinese medicine composition

The invention provides a new application of a sagittaria sagittifolia extract, a traditional Chinese medicine composition and a preparation method of the sagittaria sagittifolia extract, and the sagittaria sagittifolia extract has a remarkable treatment effect in the aspects of relieving early-stage type 2 diabetic retinopathy and reducing blood sugar and blood fat, and can be used for preparing a medicine for relieving early-stage diabetic retinopathy. The important clinical application value is realized; the traditional Chinese medicine composition is prepared from the following active ingredients in parts by weight: 50 to 70 parts of arrowhead extract, 5 to 15 parts of astragalus extract, 5 to 15 parts of radix pseudostellariae extract, 5 to 15 parts of radix rehmanniae recen extract, 5 to 15 parts of radix scrophulariae extract, 5 to 15 parts of radix salviae miltiorrhizae extract, 5 to 15 parts of radix notoginseng extract, 5 to 15 parts of radix puerariae extract and 5 to 15 parts of semen cassiae extract. The effects of relieving early diabetic retinopathy, reducing blood sugar and blood fat and inhibiting inflammatory microglial cells are obvious; the preparation method is simple, and is suitable for the requirements of large-scale industrial production.
Owner:BEIJING UNIV OF CHINESE MEDICINE

Pharmaceutical composition for treating diabetic foot and preparation method thereof

The invention provides a pharmaceutical composition for treating diabetic foot. The pharmaceutical composition comprises a traditional Chinese medicine active component, a growth factor, an antibacterial and antioxidant component, a microenvironment regulator and other auxiliary materials. The traditional Chinese medicine active components comprise 5-10 parts of a radix salviae miltiorrhizae extract, 3-8 parts of astragalus polysaccharide, 2-5 parts of dragon's blood and 1-3 parts of radix stemonae powder; the antibacterial and antioxidant components comprise 2 to 6 parts of chitosan, 0.1 to 0.5 part of nano-silver particles and 0.5 to 2 parts of vitamin E; 0.01 to 0.1 part of a growth factor; the microenvironment conditioning agent is prepared from hyaluronic acid and lactic acid according to the mass ratio of (0.1 to 0.5) to (0.05 to 0.3); the other auxiliary materials comprise 30 to 50 parts of chitosan composite hydrogel and 5 to 10 parts of glycerol. According to the invention, the traditional Chinese medicine active components are combined with the drug-loaded hydrogel to form the pharmaceutical composition with antibacterial, antioxidant and tissue regeneration promotion functions, and the pharmaceutical composition can be used for treating diabetic foot and has a good clinical application prospect.
Owner:DONGGUAN ZHIZAO BIOTECHNOLOGY CO LTD

Dye composition, hair dye containing dye composition, hair dyeing kit and use method of dye composition

The invention discloses a dye composition, a hair dye containing the dye composition, a hair dyeing kit and a use method of the dye composition. The dye composition is prepared from 10 parts of a gallnut extract, 5.7 to 13 parts of a color developing agent and 3.2 to 13.9 parts of a color matching agent; the color developing agent comprises ferrite; the toner is composed of at least one of a toner A, a toner B and a toner C; the toner A is prepared from 0.6 to 3.0 parts of pomegranate peel extract, 0.1 to 0.8 part of fructus gardeniae extract and 0.1 to 0.8 part of red sorghum extract; the toner B is prepared from 0.6 to 2.3 parts of green tea extract, 1.2 to 3.0 parts of cacumen biotae extract and 0.2 to 1.3 parts of grape seed extract; the toner C is prepared from 0.2 to 1.3 parts of radix salviae miltiorrhizae extract, 0.1 to 0.7 part of witch hazel extract and 0.1 to 0.7 part of alkannin. The dye composition has the advantages of ideal dyeing effect, short waiting time, no flooding, long retention time, natural hair dyeing color and high safety.
Owner:BEIJING XUEJI BOCHUANG BIOTECHNOLOGY CO LTD

Kudzuvine root liver-protecting composition as well as preparation method and application thereof

PendingCN122031551AOrganic active ingredientsDigestive systemOfficinalDANSHEN EXTRACT
The invention discloses a liver-protecting kudzu vine root composition and a preparation method and application thereof in the field of medicinal chemistry, and the liver-protecting kudzu vine root composition comprises a kudzu vine root extract, silymarin, a salvia miltiorrhiza extract, vitamins and two traditional Chinese medicine modified raw materials, the two modified raw materials are respectively an ester derivative formed by puerarin and aminobutyric acid and an ester derivative formed by glycyrrhizic acid and aminocaproic acid. The preparation method comprises the following steps: pre-mixing the extracts and the vitamins, adding the two modified raw materials, uniformly mixing, finally adding the pharmaceutic adjuvants, and tabletting and forming. The two modified raw materials are respectively prepared by activating puerarin or glycyrrhizic acid and corresponding aminocarboxylic acid under the action of a specific condensation reagent, condensing and purifying. According to the composition disclosed by the invention, two structurally modified active components are innovatively introduced and have a synergistic effect with a plurality of liver protection raw materials, so that the anti-oxidation, anti-inflammatory and liver protection effects are remarkably enhanced, and the composition can be used for preparing medicines or health-care products for preventing and treating alcoholic liver injury and non-alcoholic fatty liver diseases.
Owner:XIANGXI BAICAO BIOTECHNOLOGY CO LTD

Traditional Chinese medicine composition for treating orthopedic soft tissue injury and preparation method thereof

The invention belongs to the technical field of biological medicines, and particularly relates to a traditional Chinese medicine composition for treating orthopedic soft tissue injury and a preparation method thereof. The composition comprises the following raw materials in parts by weight: 4-6 parts of centella asiatica extract, 4-6 parts of salvia miltiorrhiza extract, 4-6 parts of pseudo-ginseng extract, 2-3.5 parts of eucommia ulmoides extract, 2-4 parts of liquorice extract, 4-7 parts of frankincense resin extract, 4-6.5 parts of turmeric extract and 3-4.5 parts of ligusticum wallichii extract. According to the invention, breakthrough is realized through prescription-drug delivery system-process triple synergy, and in prescription, the eight traditional Chinese medicine extracts are in multi-target synergy, and the whole process of anti-inflammation, analgesia and repair promotion is covered. On the delivery system, the hydrophilic component is included by cyclodextrin to be solubilized and stable, and the lipophilic component is efficiently transdermally loaded in the temperature-sensitive gel in the form of nanoemulsion to form a long-acting drug delivery bin on the skin. According to the process, microscopic uniformity and macroscopic stability of the system are ensured through precise low-temperature swelling, split-phase treatment and vacuum integration.
Owner:WUHAN THIRD HOSPITAL

Probiotic fermentation composition for improving athletic performance and preparation method thereof

The invention provides a probiotic fermentation composition capable of improving athletic performance and a preparation method of the probiotic fermentation composition, and belongs to the field of non-alcoholic beverages. The composition comprises the following components: a fermented red ginseng extract, a fermented radix astragali extract, a radix rehmanniae preparata extract, a radix salviae miltiorrhizae extract, a rhizoma chuanxiong extract, donkey-hide gelatin and a black tea extract. The composition prepared by a specific probiotic fermentation process has the following beneficial effects: firstly, through a multi-target synergistic effect, the motor function is systematically improved, including enhancing endurance, accelerating fatigue recovery and relieving motor-induced oxidative stress injury; 2, improving body energy metabolism and blood circulation, and promoting muscle protein synthesis and repair; thirdly, a process of firstly fermenting and then extracting is adopted, so that the bioavailability of active ingredients is remarkably improved, and the product is pure and safe; and 4, the preparation process is stable and controllable, and is suitable for physical maintenance and function improvement requirements of various groups such as athletes, middle-aged and elderly people, rehabilitation people and the like.
Owner:GUANGDONG GUYANG LIFE TECHNOLOGY CO LTD

Nrf2 activators and their use in the manufacture of a medicament

The application belongs to the technical field of medicine preparation, and particularly relates to an Nrf2 activator and application thereof in preparation of medicine. The Nrf2 activator comprises a compound I and a traditional Chinese medicine extract; a mass ratio of the compound I to the traditional Chinese medicine extract is 1-10:0.5-5; the traditional Chinese medicine extract is one or more of an astragalus extract, a radix ginseng extract, a radix salviae miltiorrhizae extract and a radix smilacae extract. The Nrf2 activator is prepared into medicine for preventing or treating diabetic nephropathy together with a pharmaceutically acceptable carrier or excipient. The Nrf2 activator can target and activate an Nrf2 signal pathway, significantly inhibit accumulation of collagen and oxidative stress, and prevent and treat diabetic nephropathy.
Owner:CHONGQING UNIV OF EDUCATION

Nasal spray for prevention and adjuvant treatment of cognitive impairment and preparation method thereof

PendingCN121731216ANervous disorderAerosol deliveryFormularyBay leaf extract
The invention relates to a nasal spray for prevention and adjuvant therapy of cognitive impairment and a preparation method thereof, and belongs to the field of health-care medicines. The formula of the nasal spray for prevention and adjuvant treatment of cognitive impairment comprises the following components in percentage by volume: a solvent the balance of water; 2%-5% of butanediol; 2%-5% of glycerin; active components: 0.01%-0.1% of a bay leaf extract; 0.01% to 0.1% of a bacopa monnieri extract; 0.01%-0.05% of a radix salviae miltiorrhizae extract; the efficient penetration enhancing and feeling adjusting components comprise 0.001%-0.1% of xanthoxylin and 0.001%-0.01% of eucalyptus globulus leaf oil; 0.001% to 0.01% of menthol; the nasal spray prepared by the invention is a composite plant extract nasal spray which is safe, effective and convenient to use, has a multi-target synergistic effect and has high brain-targeted delivery efficiency.
Owner:SHANGHAI JIAOTONG UNIV

Wet tissue for fading acne marks on face and preparation method of wet tissue

The invention discloses a wet tissue for fading face acne marks and a preparation method thereof, and belongs to the field of personal care supplies, the wet tissue comprises a wet tissue piece, a face care solution infiltrated in the wet tissue piece, and a package for accommodating the wet tissue piece; the facial care solution comprises a basic material A and an auxiliary material B, nicotinamide, tranexamic acid, a moisturizing, repairing and relieving component, a salvia miltiorrhiza extract and the like are added into the base material A and the auxiliary material B, all the components are compatible, the effects are complemented and linked, the synergistic gain effect is achieved, and meanwhile the excellent moisturizing, repairing, relieving, anti-inflammatory and antibacterial effects are achieved. The wet tissue product is free of acute skin irritation, good in tolerance to sensitive skin, free of damage to skin barriers, continuous and stable in effect after long-term use and capable of being widely applied to daily nursing of face acne marks.
Owner:JIANGSU YUNZHI MEDICAL TECHNOLOGY CO LTD

A fluffy oil control anti-dandruff composition, its preparation method and application

The present application provides a fluffy oil-control anti-dandruff composition, a preparation method and application thereof, and relates to the technical field of cosmetics. The fluffy oil-control anti-dandruff composition comprises a plant composition and an anti-dandruff composition, wherein the plant composition is composed of Capra hircus, Terminalia chebula, flower / leaf of Tamarix and Artemisia annua in a mass ratio of (1-20):20:1:10, has the effects of synergistically inhibiting Malassezia and inhibiting hyaluronidase activity; the anti-dandruff composition comprises at least one of piroctone olamine, white willow bark and salvia miltiorrhiza extract, and is used for enhancing the effects of inhibiting bacteria, controlling oil and relieving. The fluffy oil-control anti-dandruff composition can simultaneously regulate the microecological balance of the scalp, and improve the problems of dandruff, excessive oil and scalp itching caused by sensitive scalp, and can be widely used in the preparation process of products for improving dandruff, excessive oil and scalp itching caused by sensitive scalp.
Owner:GUANGDONG SANRUI HLDG GRP CO LTD +1

Composition for assisting in protecting chemical liver injury and gastric mucosal injury as well as preparation method and product thereof

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a composition for assisting in protecting chemical liver injury and gastric mucosal injury as well as a preparation method and a product of the composition. The composition is prepared from the following components in parts by weight: 35 to 45 parts of radix puerariae extract, 25 to 35 parts of semen hoveniae extract, 25 to 35 parts of radix codonopsis extract, 28 to 33 parts of radix salviae miltiorrhizae extract and 25 to 35 parts of rhizoma atractylodis macrocephalae extract. The composition has a comprehensive treatment effect on alcoholic liver injury and gastric mucosal injury by synergistically regulating lipid metabolism, oxidative stress, inflammatory response and cell signal pathways. According to the technical scheme provided by the invention, comprehensive protection on alcoholic liver injury and gastric mucosal injury is realized through multi-channel cooperative regulation and control, and the defects of single target spot and limited curative effect of the existing therapeutic drug are overcome. The technical scheme provides a safe and effective intervention measure for digestive system injury caused by alcohol, and has a wide application prospect in the field of health-care product and medicine development.
Owner:CHINA NAT RES INST OF FOOD & FERMENTATION IND CO LTD +1

Scar cream for improving scar hyperplasia and stirring cream making device thereof

The invention relates to the technical field of scar cream, in particular to scar cream for improving scar hyperplasia. Comprising the following components in parts by weight: 40 to 100 parts of matrix, 10 to 30 parts of aloe vera gel, 5 to 15 parts of glycerol, 5 to 15 parts of centella asiatica extract, 5 to 15 parts of radix salviae miltiorrhizae extract, 5 to 15 parts of radix astragali seu hedysari extract, 5 to 15 parts of herba taraxaci extract, 5 to 15 parts of curcumin, 2.5 to 7.5 parts of vitamin E oil, 1.5 to 4.5 parts of allantoin, 1 to 3 parts of sodium hyaluronate, 0.05 to 0.2 part of antioxidant, 0.05 to 0.2 part of purple perilla extract and 400 to 600 parts of deionized water, according to the invention, a plurality of components for improving scar hyperplasia are added, so that fiber hyperplasia can be effectively inhibited, regeneration and repair of dermis and epidermis can be promoted, and scars can be flat, transparent and beautiful; through combination of lifting and stirring, the stirring effect on components is improved, and through intermittent opening of the stirring mechanism, the stirring mechanism scrapes the adhered components, so that waste caused by adhesion is reduced.
Owner:JIANGSHAN PEOPLES HOSPITAL (JIANGSHAN PEOPLES HOSPITAL MEDICAL COMMUNITY JIANGSHAN OCCUPATIONAL DISEASE PREVENTION & CONTROL HOSPITAL)

Traditional Chinese medicine compound gel containing bioactive organic components and capable of synergistically repairing hypertrophic scars based on four-season qi and preparation method of traditional Chinese medicine compound gel

PendingCN120899892AOrganic active ingredientsPeptide/protein ingredientsPerilla oilDANSHEN EXTRACT
The invention relates to the technical field of biological medicine manufacturing, in particular to a traditional Chinese medicine compound gel containing bioactive organic components and capable of synergistically repairing hypertrophic scars based on four-season qi and a preparation method of the traditional Chinese medicine compound gel. The compound gel is formed by mixing a bottle A base matrix and a bottle B four-season additive according to the ratio of 9: 1, the base substrate of the bottle A contains various bioactive organic components such as a salvia miltiorrhiza extract, asiatic acid, bioactive hirudin, perilla oil and the like; according to the four-season additive in the bottle B, corresponding traditional Chinese medicine extracts are selected according to seasons, the preparation method adopts a biotechnology process including supercritical COextraction, a biocompatibility nanometer co-grinding technology and other modern biotechnologies, the transdermal absorption rate of mineral components is remarkably increased, the anti-fibrosis effect is enhanced through a hirudin-perilla oil soluble synergistic system, and the anti-fibrosis effect is improved. The four-season differentiated formula realizes accurate repair of preventing wind evil in spring, clearing blood heat in summer, moistening dryness injury in autumn and dredging collaterals in winter.
Owner:SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE