Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Prescription drug for treating cardiovascular and cerebrovascular diseases

A technology for cardiovascular and cerebrovascular diseases and drugs, which is applied to cardiovascular system diseases, drug delivery, drug combination, etc. It can solve the problems of increased amplitude and strong heartbeat, etc., to reduce free radical damage, improve antioxidant capacity, and improve drug efficacy Effect

Inactive Publication Date: 2005-03-16
TSINGHUA YUANXING BIO PHARM SCI & TECH
View PDF5 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. A small dose can slightly excite the heart, with strong heartbeat and increased amplitude

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Example 1: Preparation of prescription drug aqueous injection.

[0074] Take 1000g of safflower yellow, 1000g of puerarin, add 20,000ml of purified water for injection, dissolve, filter, prepare 2ml / branch, sterilize, and obtain a treatment with a specification of 2ml / branch, containing 100mg of safflower yellow and 100mg of puerarin 10,000 sticks of prescription drugs for cardiovascular and cerebrovascular diseases.

Embodiment 2

[0075] Embodiment 2: Preparation of prescription drug powder injection.

[0076] Take safflower yellow 1000g, puerarin 1000g, dextran S 40 150g, add 25000ml of water for injection, filter through a 0.22u microporous membrane, measure the content, and pack into 2.5ml each. Freeze-drying is ready to obtain a specification of 10,000 prescription drug powder injections for the treatment of cardiovascular and cerebrovascular diseases each containing 100 mg of safflower yellow and 100 mg of puerarin. Freeze-drying conditions: vacuum degree 750mmHg, pre-freezing temperature -40°C, pre-freezing time 2h, sublimation temperature -20°C, sublimation time 10h, first drying temperature 20°C, drying time 4h, second drying temperature 40°C, Drying time 6h.

Embodiment 3

[0077] Embodiment 3: Preparation of prescription medicine tablet.

[0078] Get 40g of sodium ferulate, 100g of troxerutin, appropriate amount of starch, dextrin, and microcrystalline cellulose, add 5-10% povidone ethanol solution, make soft material, pass through a 12-16 mesh sieve to make wet granules, Dry the wet granules at 40-60°C, add 68g of low-substituted hydroxypropyl cellulose and 1g of magnesium stearate, and press into tablets to obtain 1,000 tablets of prescription medicine for treating cardiovascular and cerebrovascular diseases, each containing sodium ferulate 40mg, Troxerutin 100mg.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Disclosed is a prescription drug for treating cardiovascular and cerebrovascular diseases which comprises the following raw materials, active constituent of safflower, active constituent of root of kudzu vine, resveratrol and its derivative, Ligustrazine and its derivative, ferulic acid and its derivative, quercetin and its derivative, rutin and its derivative or combination of any two of them, the rest are medicinal auxiliary materials. The medicine can be in the form of powder injection, liquid injection, oral liquid, capsule, slow release capsule, tablet and granule.

Description

technical field [0001] The invention relates to a prescription medicine for treating cardiovascular and cerebrovascular diseases in the technical field of medicine. The medicine described in the present invention is composed of the following ingredients: active ingredients of safflower, active ingredients of kudzu root, resveratrol and its derivatives, ligustrazine and its derivatives, ferulic acid and its derivatives, quercetin and its derivatives Combination of any two of rutin and its derivatives in any proportion, and the rest are pharmaceutical excipients. Background technique [0002] Cardiovascular and cerebrovascular diseases have seriously threatened human health and life. In 1992, Dr. Nakajima Hiroshi, Director-General of the World Health Organization pointed out: "Cardiovascular disease is the disease with the highest mortality rate in the world today. Millions of people are disabled. To make matters worse, many of the victims die prematurely under the age of 65...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/00A61K31/7048A61P9/10
Inventor 张健存王少华杨向阳
Owner TSINGHUA YUANXING BIO PHARM SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com