3 results about "Sustained Release Capsule" patented technology

This invention discloses a method for preparing nattokinase enteric-coated sustained-release capsules and sustained-release gel spheres, belonging to the field of sustained-release microcapsules. This invention improves the selection of wall materials and the preparation process, encapsulating nattokinase using a mixture of food-grade enteric-coating shellac and whey protein isolate as the wall material. After spray drying, food-grade enteric-coated microcapsules are obtained. These microcapsules are then embedded in calcium alginate gel, forming enteric-coated gel spheres through stepwise encapsulation. The gel spheres prepared by this invention are safe for consumption, have a high encapsulation rate, are resistant to gastric acid, can be released into the intestines, are easy to store and transport, and can be mass-produced industrially.

The application provides a hydrophobic slow-release capsule and a rheology-adjusted high-performance accelerator, wherein the hydrophobic slow-release capsule can release hydrophobic components in time sequence under the dual response of pH / time, solves the problems of the existing shotcrete technology, such as contradiction between the accelerating function and the hydrophobic function, high rebound rate, large late strength loss, poor anti-permeation and anti-corrosion capacity, and has good application effect in wet shotcrete construction.

The application belongs to the technical field of chemical medicine sustained-release preparation, and proposes a glipizide sustained-release capsule and a preparation method thereof.The glipizide sustained-release capsule is prepared by filling microtablet A with a release time interval of 0-6h and microtablet B with a release time interval of 6-12h in a quantity of 2:3;wherein, the microtablet A comprises glipizide, a skeleton material, a filler, an aqueous binder solution and a lubricant; the microtablet B is prepared by coating the capsule prescription amount of 60% of the microtablet A with a sustained-release coating. By designing two kinds of release microtablets in the sustained-release capsule, the two kinds of microtablets are responsible for their respective release intervals, and are mutually coordinated and supplemented to realize a smooth release curve, and the in-vitro release behavior of the original preparation is highly coincident, and the preparation process of the two kinds of microtablets can be coordinated, and has a greater adjustment space.