12 results about "Sustained Release Capsule" patented technology

1. The name of the designed product: packing box (ibuprofen sustained-release capsule). 2. The use of the designed product: the designed product is used for medicine packing. 3. The design points of the designed product: the combination of shape, pattern and color. 4. The picture or photo that best shows the design points: perspective view. 5. The design contains color.

The invention relates to the technical field of curing agents, in particular to a soil curing agent and a preparation method thereof.The soil curing agent is prepared from, by weight, 180-220 parts of fly ash, 160-180 parts of slag, 80-120 parts of calcium salt, 80-120 parts of potassium nitrate, 10-14 parts of microbial agents, 40-60 parts of sustained-release capsule particles and 20-30 parts of biological stimulants. Therefore, the soil structure is improved, and the content of large aggregates in the soil can be remarkably increased.

The present application relates to the technical field of pharmaceutical preparation, in particular to a sustained-release capsule for treating gastric ulcer and a preparation method thereof; the present application takes the traditional formula of Weike Ning as the basis and improves it, uses aluminum magnesium carbonate to replace the traditional white vitriol, the release amount of aluminum ions in the aluminum magnesium carbonate is much lower than that of the white vitriol, and most of the aluminum ions will form insoluble complexes in the intestinal tract and be discharged out of the body, so that the risk of accumulation in the body is extremely low, thereby reducing the side effects on the nervous system and the skeletal system; and the medicine is also subjected to gastric floating and sustained-release treatment, so that the medicine can float above the gastric juice, prolong the residence time of the medicine in the stomach and release slowly, thereby realizing the slow release of the medicine in the stomach and avoiding the defect that the medicine needs to be taken multiple times.

This invention discloses a method for preparing nattokinase enteric-coated sustained-release capsules and sustained-release gel spheres, belonging to the field of sustained-release microcapsules. This invention improves the selection of wall materials and the preparation process, encapsulating nattokinase using a mixture of food-grade enteric-coating shellac and whey protein isolate as the wall material. After spray drying, food-grade enteric-coated microcapsules are obtained. These microcapsules are then embedded in calcium alginate gel, forming enteric-coated gel spheres through stepwise encapsulation. The gel spheres prepared by this invention are safe for consumption, have a high encapsulation rate, are resistant to gastric acid, can be released into the intestines, are easy to store and transport, and can be mass-produced industrially.

The utility model provides an urapidil hydrochloride sustained-release capsule medicament oscillating granulator, belongs to the technical field of granulation equipment, and aims to solve the problem that the mounting effect of a screen is relatively low due to the fact that two ends of the screen need to be clamped independently in the prior art. Comprising a granulator base, a granulator main body, a feeding hopper, a granulation driving roller, a screen clamping pipe, a discharging fixing mechanism and an auxiliary mounting mechanism, the granulator main body is fixedly connected to the upper part of the granulator base; the feeding hopper is fixedly connected to the upper end of the front part of the granulator main body; the granulation driving roller is rotationally connected to the middle position of the inner side of the feeding hopper; the number of the screen clamping pipes is two, the two screen clamping pipes are connected to the inner side of the feeding hopper in an inserted mode, and spline structures are arranged at the front ends of the peripheries of the two screen clamping pipes; the blanking fixing mechanism is arranged above the granulator base; the installation auxiliary mechanism is arranged on the inner side of the feeding hopper, operation of workers is facilitated, operation steps of the workers are reduced, and the installation efficiency of the screen is improved.

The application provides a hydrophobic slow-release capsule and a rheology-adjusted high-performance accelerator, wherein the hydrophobic slow-release capsule can release hydrophobic components in time sequence under the dual response of pH / time, solves the problems of the existing shotcrete technology, such as contradiction between the accelerating function and the hydrophobic function, high rebound rate, large late strength loss, poor anti-permeation and anti-corrosion capacity, and has good application effect in wet shotcrete construction.

The invention discloses a sustained-release capsule as well as a preparation method and application thereof. The sustained-release capsule is of a core-shell structure, the sustained-release capsule comprises a capsule core and a composite capsule wall, the composite capsule wall wraps the outer side of the capsule core, and the composite capsule wall comprises an inert isolation layer, an inner capsule wall and an outer capsule wall which sequentially wrap the outer side of the capsule core from inside to outside; wherein the capsule core comprises a carbonate ion source; the inert isolation layer is made of a hydrophobic high polymer material with chemical inertness; the inner capsule wall is formed by carrying out hydration pretreatment and carbonization pretreatment on a cement-based material; and the outer capsule wall is made of an alkali-activated degradable high polymer material. Through collaborative design of the core-shell structure and the multiple layers of capsule walls, delayed release of the carbonate ion source in the cement-based material service process is achieved, and the problem that carbonate ions are insufficient in supply in the carbonization reaction process is solved.

This invention belongs to the field of oral solid dosage form technology and relates to a loratadine sustained-release capsule and its preparation method. This application provides a loratadine-containing sustained-release capsule, wherein loratadine is melt-mixed with citric acid and salicylic acid to prepare a drug-containing core, and the core is coated with a sustained-release layer, an immediate-release layer, and a protective layer. This not only effectively solves the problem of slow dissolution of loratadine in the presence of insufficient gastric acid, but also ensures uniform drug release, achieving long-lasting effects and increased efficacy.

The present application provides a kind of isosorbide mononitrate sustained-release capsules and its preparation method, the isosorbide mononitrate sustained-release capsule of the present application, characterized in that, the drug loading layer, sustained-release layer, immediate-release layer and protective layer of the isosorbide mononitrate sustained-release capsule are respectively coated by fluidized bed granulation coating machine.The granular preparation has good stability, small side effect;The preparation process of the isosorbide mononitrate sustained-release capsule of the present application is simple, the equipment is simple and easy to operate, the labor intensity is small, and it is economic and safe.At the same time, the prescription and preparation method are more economical, and are suitable for industrial production.

The utility model provides a metal detector for urapidil hydrochloride sustained-release capsule production, belongs to the technical field of pharmaceutical detection, and aims to solve the problems that an existing metal detector for urapidil hydrochloride sustained-release capsule production is large in capsule collecting box gap, low in space utilization rate and low in compatibility between a material conveying machine pipeline and a feeding port. Comprising a mounting base, a supporting rod, a metal detector body, a controller body, a connecting disc, a placement table, a limiting assembly and a vibration assembly, and the supporting rod is fixedly mounted on the upper portion of the mounting base; the metal detector main body is slidably connected to the outer side of the supporting rod; the controller main body is fixedly mounted at the top of the metal detector main body; the connecting disc is arranged on the outer side of the metal detector main body; the placing table is arranged at the upper part of the mounting base; the limiting assembly is arranged in the connecting disc; and the vibration assembly is arranged in the mounting base. The utility model has the advantages of high adaptability, convenience in use, improved space utilization rate and the like.

The invention provides a mesalazine-containing slow-release solid dispersion and a preparation method thereof, and provides a mesalazine-containing slow-release solid dispersion in order to solve the problems that the existing mesalazine solid dispersion is poor in stability, free of targeting and easy to degrade in the preparation process. The solubility is high (the solubility is improved by 25-30 times compared with that of an original drug), the sustained release within 12 hours is controllable (accurate release in a colon segment, and the cumulative release rate within 12 hours reaches 85-90%), and the accelerated storage stability is high (the crystallization rate lt in 6 months; 3%, and the drug content gt; 98% and the ethanol residue 1t; 0.3%) and the like. The sustained-release solid dispersion provided by the invention and pharmaceutically acceptable auxiliary materials are prepared into sustained-release tablets or sustained-release capsules, and the sustained-release solid dispersion can be used for preparing oral preparations for treating inflammatory bowel diseases, can improve the drug concentration of diseased regions of intestinal tracts and reduce untoward effects of the whole body, and has remarkable clinical application value.

The application belongs to the technical field of chemical medicine sustained-release preparation, and proposes a glipizide sustained-release capsule and a preparation method thereof.The glipizide sustained-release capsule is prepared by filling microtablet A with a release time interval of 0-6h and microtablet B with a release time interval of 6-12h in a quantity of 2:3;wherein, the microtablet A comprises glipizide, a skeleton material, a filler, an aqueous binder solution and a lubricant; the microtablet B is prepared by coating the capsule prescription amount of 60% of the microtablet A with a sustained-release coating. By designing two kinds of release microtablets in the sustained-release capsule, the two kinds of microtablets are responsible for their respective release intervals, and are mutually coordinated and supplemented to realize a smooth release curve, and the in-vitro release behavior of the original preparation is highly coincident, and the preparation process of the two kinds of microtablets can be coordinated, and has a greater adjustment space.