73 results about "Sustained Release Capsule" patented technology

The invention provides a microbial slow-release porous composite material for sewage treatment as well as a preparation method and application thereof. The preparation method comprises the following steps: dropwise adding an organic ligand solution into a precursor solution consisting of a nanocellulose solution and a cobalt source solution; mixing the reaction solution with polyvinyl alcohol, injecting the mixture into a mold, and performing directional freezing to obtain an aerogel matrix; carrying out hydrophobic modification on the aerogel matrix to obtain a modified aerogel matrix; mixing the microbial suspension with sodium alginate, and homogenizing at high pressure to obtain a gel precursor emulsion; the preparation method comprises the following steps: dropwise adding a calcium chloride solution to gelatinize to obtain gel particles, and then cross-linking and drying by glutaraldehyde to obtain sustained-release capsule particles; dispersing the sustained-release capsule particles in deionized water to obtain dispersion liquid; and dipping the modified aerogel matrix in the dispersion liquid. An aerogel matrix with a hierarchical porous structure is compounded with a sustained-release capsule with a pH response mechanism, so that physical adsorption, chemical catalysis and biodegradation for sewage treatment are realized.

The invention relates to the field of hygienic products, in particular to a bacteriostatic non-menstrual-period panty liner based on a sustained-release capsule and a preparation method thereof.It is found through screening that matrine and lactein have the synergistic bacteriostatic effect, the bacteriostatic composition is prepared into a sustained-release microcapsule, long-acting sustained release of antibacterial components is achieved, and the antibacterial effect is good. The sustained-release capsule is prepared into the bacteriostatic non-menstrual period protection pad based on the sustained-release capsule. The air permeability and the moisture permeability of the protection pad are superior to those of the prior art, the comfort and the safety of non-menstrual female hygiene care are remarkably improved, and the protection pad is suitable for daily hygiene maintenance and infection prevention.

The invention provides a cutting woven type stent, and belongs to the technical field of medical instruments for treating vascular diseases. The stent comprises an intravascular stent body, a medicine carrying groove used for containing medicine is formed in the outer surface of the intravascular stent body, sustained-release capsules are fixedly distributed in the medicine carrying groove, each sustained-release capsule is provided with a shell, a containing cavity is formed in the shell, and medicine particles and a shell breaking component are loaded in the containing cavities of part of the sustained-release capsules; the medicine assembly for rapidly treating intracranial vascular stenosis further comprises a driving component, and the driving component is arranged in vitro and used for driving the shell breaking component to rapidly break the shell so as to rapidly release medicine particles in the shell. The drug eluting stent is mainly used for solving the technical problem that a drug eluting stent in the prior art cannot quickly release drugs and cannot quickly generate a treatment effect.

The invention relates to a diltiazem hydrochloride sustained-release capsule, the content of the sustained-release capsule comprises a diltiazem hydrochloride sustained-release micro-tablet, and the diltiazem hydrochloride sustained-release micro-tablet comprises diltiazem hydrochloride, a release adjusting material and a hydrophilic gel material, the in-vitro release degree similarity factor f2 of the sustained-release capsule and a commercially available diltiazem hydrochloride sustained-release capsule produced by Mylan company is greater than 50. The diltiazem hydrochloride sustained-release capsule disclosed by the invention has an in-vitro release degree similar to that of a commercially available reference preparation, and is simple in production process, low in material cost and easy for industrial mass production.

The invention relates to the technical field of sustained-release capsules, and particularly discloses a tamsulosin sustained-release capsule based on an instant coating and a preparation method of the tamsulosin sustained-release capsule. Comprising the following steps: S1, taking microcrystalline cellulose and talcum powder, and mixing to obtain a dry material; adding tamsulosin hydrochloride into water to prepare a liquid medicine; taking the methacrylic acid-ethyl acrylate copolymer dispersion liquid, adding glycerol triacetate and sodium carboxymethyl cellulose, and uniformly stirring to obtain a granulation dispersion liquid; s2, preparing pellets from the liquid medicine, the dry material and the granulation dispersion liquid; s3, taking the methacrylic acid-ethyl acrylate copolymer dispersion liquid, adding water, glycerol triacetate and the modified polyacrylate emulsion, and uniformly stirring; adding talcum powder, and uniformly stirring to obtain a coating solution; coating the pellets with a coating solution to obtain coated pellets; and S4, mixing talcum powder, calcium stearate and the coated pellets, and filling capsules with the mixture to obtain the tamsulosin sustained-release capsules.

The invention relates to the technical field of sustained-release capsules, in particular to a memantine hydrochloride sustained-release capsule and a preparation method thereof. The memantine hydrochloride sustained-release capsule disclosed by the invention is formed by filling memantine hydrochloride sustained-release pills; the sustained-release pill sequentially comprises a blank pill core, a main medicine layer, an isolation coating layer and a sustained-release coating layer from inside to outside, the main medicine layer is prepared from the following raw materials in parts by weight: 25 to 30 parts of memantine hydrochloride, 3 to 7 parts of hydroxypropyl methyl cellulose E, 1 to 2 parts of medicine carrying microspheres, 20 to 30 parts of PEG6000 and 4 to 5 parts of talcum powder. The memantine hydrochloride sustained-release capsule disclosed by the invention is small in release amount difference no matter in 0d or 10d, not only meets the sustained-release standard, but also can exist relatively stably, and a burst release phenomenon is avoided.

The invention discloses a CO2 sustained-release capsule and a preparation method thereof. The CO2 sustained-release capsule comprises sodium alginate, corn starch, amyloglucosidase, saccharomyces cerevisiae and anhydrous calcium chloride, and a solvent is ultrapure water. The saccharomyces cerevisiae is Saccharomyces cerevisiae BNCC185415, and the saccharomyces cerevisiae is Saccharomyces cerevisiae BNCC185415. The mass ratio of the sodium alginate in the capsule preparation is 2.00%-3.00%, the mass ratio of the corn starch in the capsule preparation is 10.00%-30.00%, the content of the amyloglucosidase in the capsule preparation is 1.0-3.0 U / g, and the mass ratio of the saccharomyces cerevisiae in the capsule preparation is 10.0%-30.0%. Based on the general taxis of underground pests to CO2, the invention creates a CO2 sustained-release capsule which has remarkable attraction activity on the pests, and the underground pests can be trapped, killed, prevented and controlled by combining physical prevention and control, biological prevention and control, chemical prevention and control and other measures in practical application.

The application discloses a foam displacement agent sustained-release capsule and a preparation method and application thereof. The foam displacement agent sustained-release capsule comprises a sustained-release film and a foam displacement agent coated in the sustained-release film; and the sustained-release film is a polymer film. The foam displacement agent sustained-release capsule has a sustained-release time of greater than 2 days under the gas well conditions of a temperature of 100-160 DEG C and a pH of 3-6, and the foamability, foam stability and liquid carrying capacity of a solution reach a peak value when the sustained-release time is 2-4 days, at which time, the liquid carrying capacity is greater than or equal to 120 mL, the foamability is greater than or equal to 140 mm, and the foam stability is greater than or equal to 120 mm. The foam displacement agent sustained-release capsule has good foamability, foam stability and liquid carrying capacity.

1. The name of the designed product: packing box (ibuprofen sustained-release capsule). 2. The use of the designed product: the designed product is used for medicine packing. 3. The design points of the designed product: the combination of shape, pattern and color. 4. The picture or photo that best shows the design points: perspective view. 5. The design contains color.

The invention discloses a preparation method of a magnesium glycinate enteric-coated sustained-release capsule, and relates to the technical field of preparation of enteric-coated sustained-release capsules, and the preparation method is technically characterized by comprising the following steps: preparing a magnesium glycinate pellet: mixing magnesium glycinate with microcrystalline cellulose, starch and cane sugar to form uniform powder, adding the mixed powder into a centrifugal granulating and coating machine, and carrying out granulation and coating to obtain the magnesium glycinate pellet; taking hydroxypropyl methyl cellulose or a methyl cellulose solution as an adhesive, and performing centrifugal granulation at four stages of nucleation, coalescence, lamination and rolling compaction to obtain magnesium glycinate pellets; the nucleation is that the initial particles attract and are connected with one another due to the formation of a three-phase structure in the wetting process of the adhesive; the coalescence is that parent nuclei are combined to form larger particles due to random collision among the large particles; through a synergistic process of four-stage centrifugal granulation, specific-ratio slow-release coating and HPMCP enteric coating, efficient and accurate controlled release of magnesium glycinate is realized, and the problem of too fast release caused by insufficient weight gain of the slow-release coating is effectively avoided.

The invention provides a dapsone sustained-release capsule and a preparation method thereof, the capsule contains a sustained-release solid drug pellet, the pellet is composed of a drug pellet core and an isolating layer coating, the pellet core mainly contains dapsone, and an adhesive, a filler and a lubricant are supplemented. The isolating layer coating comprises an anti-sticking agent, a water-soluble pore-foaming agent, an antistatic agent and a non-PH-dependent low-permeability polymer, so that accurate slow release of the medicine is realized. In addition, the invention also provides a scheme of adding the plant extract glycyrrhizin into the dapsone sustained-release capsule, so that the synergistic interaction is realized, and the curative effect and safety of the medicine are improved. The quality and stability of the medicine are ensured by optimizing the prescription of the medicine pill core and accurately controlling the composition of the isolating layer coating. The preparation method adopts a powder lamination method to prepare uncoated pills, and then coating is performed, so that the process is simple and suitable for industrial production. According to the dapsone sustained-release tablet, the sustained-release effect of dapsone is achieved, the treatment effect is improved by adding glycyrrhizin, and a better treatment choice is provided for patients.

The present invention provides a kind of ink with lasting fragrance and preparation method thereof, belong to the field of ink technology, the ink with lasting fragrance comprises the following raw materials in parts by weight: 20-40 parts of tripropylene glycol diacrylate, 10-20 parts of trimethylolpropane triacrylate, 20-50 parts of polyurethane acrylate, 1-5 parts of silicone acrylate, 4-6 parts of photoinitiator, 1-5 parts of active amine co-initiator, 3-5 parts of fragrance sustained-release capsule, 0.3-0.5 parts of defoamer, 5-15 parts of solvent; wherein, the fragrance sustained-release capsule is composed of an oil phase consisting of plant essential oil, polylactic acid-co-glycolic acid copolymer, PCL-PEG grafted cyclodextrin and ethyl acetate, and an aqueous phase consisting of polyvinyl alcohol in water, and is made by high-pressure homogenization, rotary evaporation and drying. The ink fragrance prepared by the present invention lasts for a long time and has the characteristics of good stability, strong adhesion, fast curing, scratch resistance, and green environmental protection.

The invention relates to the field of aromatherapy wax, in particular to an environment-friendly aromatherapy candle capable of removing formaldehyde and a preparation process of the environment-friendly aromatherapy candle. Raw materials of the aromatherapy wax comprise the following components in parts by mass: 45-55 parts of modified vegetable wax, 3-8 parts of a plant essential oil mixture, 1-3 parts of a stabilizer, 2-3 parts of a dispersant and 6-10 parts of a sustained-release capsule, and the sustained-release capsule comprises a core material and a wall material, the core material is prepared from modified hydroxyapatite, tea polyphenol modified nano ZnO and a gynostemma pentaphyllum extract. The problems that aromatherapy formaldehyde removal efficiency is low, collapse is prone to occurring, fragrance release is too fast, fragrance is dissipated within a short time, and lasting fragrance cannot be achieved are solved. The environment-friendly aromatherapy candle capable of removing formaldehyde can efficiently remove indoor formaldehyde for a long time, can keep lasting faint scent, and is stable in structure and not prone to collapse.

1. Name of the designed product: packing box (ibuprofen sustained-release capsule). 2. Use of the designed product: the designed product is used for packing. 3. Design points of the designed product: the pattern. 4. Picture or photo best indicating the design points: front view.

The invention provides a carvolevodopa sustained-release capsule and a preparation method thereof. The carvolevodopa sustained-release capsule comprises a cured hollow soft capsule, and the cured hollow soft capsule is sequentially coated with a drug-containing layer and a thin film layer; the cured hollow soft capsule is obtained by curing a hollow soft capsule with a curing agent; the drug-containing layer comprises carbidopa, levodopa, a sustained-release material and an adhesive. The cardopa-levodopa sustained-release capsule provided by the invention has a unique gastric floating mechanism, has better gastric floating performance, and also has an in-vitro dissolution curve similar to that of a reference preparation. Meanwhile, raw materials and auxiliary materials are easy to obtain in the preparation process of the Carbidopa-levodopa sustained-release capsule, the preparation process is simple, the cost is low, and continuous and commercialized production is facilitated.

The invention relates to the technical field of medicines, discloses a salted fructus gardeniae sustained-release capsule, and relates to the technical field of medicines. The sustained-release capsule comprises a salted gardenia extract, a specific framework material, a filling agent, an adhesive and a disintegrating agent. Through a unique preparation process, the salted fructus gardeniae extract is prepared into quick-release particles and slow-release particles respectively, and then the quick-release particles and the slow-release particles are mixed according to a specific proportion and filled into capsule shells. The salted fructus gardeniae extract is obtained by adopting an ethanol reflux extraction method, and slow and stable release of the medicine is realized by virtue of an optimized prescription and process.

The invention relates to the technical field of sustained-release capsules, and specifically discloses a tamsulosin sustained-release capsule based on a quick-dissolving coating and a preparation method thereof; the method comprises the following steps: S1: taking microcrystalline cellulose and talcum powder, mixing to obtain a dry material; adding tamsulosin hydrochloride into water to prepare a drug solution; taking a methacrylic acid-ethyl acrylate copolymer dispersion, adding triacetin and sodium carboxymethyl cellulose, stirring evenly to obtain a granulation dispersion; S2: preparing micropills with the drug solution, the dry material and the granulation dispersion; S3: taking a methacrylic acid-ethyl acrylate copolymer dispersion, adding water, triacetin and a modified polyacrylate emulsion, stirring evenly; adding talcum powder, stirring evenly to obtain a coating solution; coating micropills with the coating solution to obtain coated micropills; S4: taking talcum powder, calcium stearate and coated micropills, mixing, and filling into capsules to obtain tamsulosin sustained-release capsules.

The invention discloses a sustained-release material for improving the fracture resistance of a cement-based material and application, and belongs to the technical field of building material admixtures. The sustained-release material for improving the fracture resistance of the cement-based material comprises a solution A and a solution B, the solution A is formed by mixing an alkali-activated sustained-release capsule and a monomer solution; the monomer solution is an acrylamide solution or a sodium acrylate solution, and the solution B is an oxidizing initiator solution; the alkali-activated sustained-release capsule comprises an inner core, a middle coating layer and an outer coating layer, the inner core is nano silicon dioxide, the middle coating layer is nano silicon dioxide modified by tertiary amine groups, and the outer coating layer is nano silicon dioxide; the mass ratio of the alkali-activated sustained-release capsule to the active ingredients in the monomer solution to the active ingredients in the solution B is (1-30): 30 (0.03-0.3). The sustained-release material is wide in raw material source, safe and environment-friendly, the preparation process is simple and easy to control, and the sustained-release material can improve the fracture resistance without influencing hydration of the cement-based material.

The present invention belongs to the technical field of pesticides, and specifically relates to a nano fluazinam sustained-release agent and a preparation method and application thereof. The nano fluazinam sustained-release agent provided by the present invention comprises a sustained-release capsule dispersed in water, wherein the sustained-release capsule is a core-shell structure, the core of the core-shell structure is fluazinam original drug, and the shell of the core-shell structure is a carrier and a surfactant; the carrier material is ethyl cellulose or polylactic acid; the surfactant comprises one or more of maleic rosin polyoxypropylene oxyethylene ether sulfonate, maleic rosin octylphenol polyoxyethylene ether diester acid sodium salt, polyvinyl alcohol, polyoxyethylene ether, polyoxyethylene alcohol, polyurethane, polyethylene glycol, polyvinyl alcohol, polyvinyl ether and polyvinyl amide. The surfactant and the carrier are combined together by intermolecular forces or cross-entanglement between molecular chains, which can reduce the surface tension of the fluazinam sustained-release agent while reducing the release rate of fluazinam, so as to prolong the effective period and improve the utilization rate of the agent.

The invention relates to the technical field of curing agents, in particular to a soil curing agent and a preparation method thereof.The soil curing agent is prepared from, by weight, 180-220 parts of fly ash, 160-180 parts of slag, 80-120 parts of calcium salt, 80-120 parts of potassium nitrate, 10-14 parts of microbial agents, 40-60 parts of sustained-release capsule particles and 20-30 parts of biological stimulants. Therefore, the soil structure is improved, and the content of large aggregates in the soil can be remarkably increased.

The invention relates to the field of pharmaceutical preparations, and discloses a tamsulosin hydrochloride sustained-release capsule and a preparation method thereof.The sustained-release capsule is prepared from, by mass, 0.1%-0.2% of tamsulosin hydrochloride, 5%-20% of sustained-release framework material and 80%-95% of filler, the sustained-release framework material is methacrylic acid-ethyl acrylate copolymer, and the filler is a filler. The filling agent comprises starch and microcrystalline cellulose; the dissolution behavior of the sustained-release capsule is consistent with that of an original development agent; the starch in the sustained-release capsule can remarkably reduce the dosage of the methacrylic acid-ethyl acrylate copolymer, and the production cost is remarkably reduced while the weight and the sustained-release effect of the sustained-release capsule are not changed; according to the preparation method of the tamsulosin hydrochloride sustained-release capsule, water with the water temperature being greater than or equal to 50 DEG C is selected as a solvent of tamsulosin hydrochloride, so that the pill preparation yield is remarkably improved, the production efficiency is remarkably improved, and the pill uniformity is remarkably improved.

The invention relates to the technical field of pharmaceutical preparations, in particular to a mannitol-starch ester bond conjugate colon-targeted sustained-release capsule and a preparation method and application thereof, and the capsule is composed of a mannitol-starch ester bond conjugate pellet, an enteric coating layer, an electrolyte compensation agent and a taste regulator; 90% of drugs of the sustained-release capsule can be accurately released in the colon, animal experiments show that compared with PEG-ELS, the Boston score of the capsule is 3-4 (vs 1-2), the dehydration risk of the capsule is reduced, the survival rate of the capsule is high, all the raw materials are medicinal, the process can be amplified to 10 kg batch, equipment is a conventional fluidized bed and a capsule filling machine, and the production process and equipment are simple.

The present application relates to the technical field of pharmaceutical preparation, in particular to a sustained-release capsule for treating gastric ulcer and a preparation method thereof; the present application takes the traditional formula of Weike Ning as the basis and improves it, uses aluminum magnesium carbonate to replace the traditional white vitriol, the release amount of aluminum ions in the aluminum magnesium carbonate is much lower than that of the white vitriol, and most of the aluminum ions will form insoluble complexes in the intestinal tract and be discharged out of the body, so that the risk of accumulation in the body is extremely low, thereby reducing the side effects on the nervous system and the skeletal system; and the medicine is also subjected to gastric floating and sustained-release treatment, so that the medicine can float above the gastric juice, prolong the residence time of the medicine in the stomach and release slowly, thereby realizing the slow release of the medicine in the stomach and avoiding the defect that the medicine needs to be taken multiple times.

The invention relates to the technical field of pharmaceutical preparations. The invention provides a sustained-release capsule containing minoxidil and dutasteride and a preparation method of the sustained-release capsule, the sustained-release capsule is composed of a capsule shell and content, and the content comprises minoxidil, dutasteride, spirolactone, isovitamin A, a traditional Chinese medicine composition, a sustained-release material, a filling material, an adhesive, a lubricant, a traditional Chinese medicine solubilizing dispersant and a stabilizer. According to the sustained-release capsule, through the synergistic effect of chemical components and traditional Chinese medicine components, the medicine components are better and more stable, the duration time of the medicine effect is prolonged, and the side effects of hirsutism, edema and the like caused by minoxidil and the side effects of transaminase abnormality and the like caused by dutasteride are reduced; meanwhile, by means of the liver protecting and blood nourishing effects of the traditional Chinese medicine components, the liver metabolism pressure is better reduced, and the long-term medication safety is improved; the hair regeneration capability is enhanced, and a better alopecia prevention and treatment effect is achieved.

The invention provides a verapamil hydrochloride sustained-release capsule with stable release rate during storage, the sustained-release capsule content comprises a sustained-release coated pellet, and the sustained-release coated pellet comprises (a) a blank pellet core, (b) a drug coating layer wrapping the blank pellet core, and (c) a sustained-release coating layer wrapping the drug coating layer; the drug coating layer comprises verapamil hydrochloride and a release stabilizer, and the in-vitro release degree similarity factor f2 of the sustained-release capsule after being placed for a long time under the conditions of 40 DEG C and RH of 75% and the sustained-release capsule before being placed is greater than 50. The verapamil hydrochloride sustained-release capsule effectively solves the problem that the in-vitro release degree is unstable in the storage process of the verapamil hydrochloride sustained-release capsule, and the clinical medication safety of the preparation within the storage validity period is greatly improved.

The present invention relates to a high expansion rate algae dietary fiber sustained-release capsule and its preparation method and application, the sustained-release capsule, including a core material and a wall material, the mass ratio of the core material to the wall material is 1: (1-3); in parts by mass, the core material includes 15-25 parts of probiotics, 5-15 parts of carboxymethyl cellulose, and 5-10 parts of chitosan; the wall material includes 20-30 parts of algae dietary fiber and 10-20 parts of resistant dextrin, and the core material forms a self-assembled coating on the surface of the probiotics through the electrostatic adsorption of carboxymethyl cellulose and chitosan; the expansion force of the algae dietary fiber is greater than 100mL / g, and the water holding capacity is greater than 10000%; the core material and the wall material are prepared by a negative pressure low-temperature spray drying method to obtain the sustained-release capsule. The wall material algae dietary fiber and the resistant dextrin of the sustained-release capsule of the present invention have a good taste, increase satiety, and are combined with the core material probiotics released by intestinal positioning to contribute to intestinal peristalsis and promote intestinal health.

The invention discloses a yam rhizome Tongli traditional Chinese medicine composition and application thereof, and belongs to the technical field related to traditional Chinese medicine, the yam rhizome Tongli traditional Chinese medicine composition comprises yam rhizome, rhizoma acori graminei, radix paeoniae rubra, spina gleditsiae, radix ranunculi ternati, verbena, fructus rosae laevigatae, fructus alpiniae oxyphyllae, lophatherum gracile, radix cyathulae, radix linderae and angelica sinensis, and the yam rhizome Tongli traditional Chinese medicine composition can synchronously eliminate dampness and heat and reinforce the kidney and reduce urination, can inhibit pathogens, and has the effects of clearing heat and eliminating dampness and The pharmaceutical composition can be used for treating both symptoms and root causes, improving local microcirculation, promoting blood circulation and regulating smooth muscle functions, and can be combined with tamsulosin hydrochloride sustained-release capsules to play a synergistic effect, improve urination function, reduce residual urine and infection risks, relieve pain and inflammation, treat both symptoms and root causes and reduce recurrence rate.

1. Name of the product of this design: packaging box (ibuprofen sustained-release capsules). 2. Purpose of this design product: used for packaging products. 3. The design key point of this appearance design product lies in the combination of shape and pattern. 4. The picture or photo that best illustrates the design points: expanded state diagram.

The present invention provides a highly permeable concrete protective coating and a preparation method thereof. The raw materials for preparing the concrete protective coating include a powder and a liquid. The powder comprises, by weight, 40 to 60 parts of Portland cement, 2 to 4 parts of nano-silica, 30 to 40 parts of quartz sand, and 8 to 12 parts of silicate. The liquid comprises, by weight, 15 to 20 parts of siloxane oligomers, 20 to 30 parts of acrylic emulsion, and 4 to 6 parts of sustained-release capsules. The sustained-release capsules use graphene oxide as the capsule wall and zirconium silicone as the capsule core. In the present invention, siloxane oligomers are introduced to replace traditional volatile, non-environmentally friendly solvents. Nano-silica and silicate are combined to react with concrete to hydrate and fill the micropores of the mortar, synergistically enhancing the density and impermeability of the concrete and improving the permeability of the coating. The introduction of sustained-release capsules can enhance the compressive strength of the concrete and extend its service life.

The utility model discloses a portable slow-release capsule storage device which comprises a box body, a containing groove is formed in the inner bottom wall of the box body, a sponge block is fixedly installed in the containing groove, a capsule groove is formed in the top of the sponge block, and a slow-release capsule is arranged in the capsule groove. The slow-release capsule can be located in the sponge block, a box cover is hinged to the top of the box body, the bottom of the box cover is connected with a pressing plate through a spring, a sponge layer is installed at the bottom of the pressing plate, and after the box cover is closed, the sponge layer at the bottom of the pressing plate can be pressed on the slow-release capsule through the elastic effect of the spring, and then the slow-release capsule is located. Loud sound caused by collision between the capsules or between the capsules and the inner wall of the box body when the capsules are carried outdoors is avoided, and the shells of the capsules are effectively prevented from being broken.