617 results about "Divalent metal ions" patented technology

This invention provides methods for massive parallel nucleic acid analysis. A closed complex of nucleic acid template, nucleotide and polymerase can be formed during polymerase reaction, absent divalent metal ion. This is used to trap the nucleotide complementary to the next template nucleotide in the closed complex. Detection of the trapped nucleotide allows determination of the sequence of this next correct nucleotide. In this way, sequential nucleotides of a nucleic acid template can be identified, effectively determining the sequence. This method is applied to sequence multiple templates in parallel, particularly if they are immobilized on a solid support.

The invention provides a corrosion-inhibiting anionic intercalated hydrotalcite/nano oxide composite material, a preparation method thereof and application of the corrosion-inhibiting anionic intercalated hydrotalcite/nano oxide composite material. The preparation method is as follows: corrosion-inhibiting anions are directly inserted between hydrotalcite layers by the one-step coprecipitation method and the roasting restoring method; the nano oxide is generated by means of in situ synchronization during the process of generation of hydrotalcite crystals by controlling the mixture ratio of divalent metal ions to trivalent metal ions, the pH value of a reaction solution and the reaction temperature; and the corrosion-inhibiting anionic intercalated hydrotalcite/nano oxide composite material with the anti-corrosive function is prepared. The invention is mainly characterized in that the in situ preparation method for the hydrotalcite/oxide composite material provided with a nano lamellar structure improves the release amount of a corrosion inhibitor and reduces the water absorption of a coating by leading into the corrosion inhibitor with the anti-corrosive function and the nano oxide which is generated in situ during the reaction process. The composite material can be used to be pigment of an anti-corrosive metallic coating system, and particularly has potential application value in improving the anti-corrosive performance of a magnesium alloy anti-corrosive coating.

The invention relates to a layered double hydroxide and a preparation method thereof, belonging to the technical field of metal hydroxide preparation. A chemical formula of the layered double hydroxide is as follows: (M1(1-x)M2x(OH)2)(A<n->)x/n), wherein x is larger than or equal to 0.2 and smaller than or equal to 0.33; M1 represents any one or more of divalent metal ions including Mg<2+>, Zn<2+>, Ni<2+>, Co<2+>, Ca<2+>, Cu<2+>, Fe<2+> and Mn<2+>; M2 represents any one or two of trivalent metal ions including Fe<3+> and Al<3+>; A<n-> represents any one of interlayer anions including CO3<2->,NO3<->, Cl<-> and SO4<2->; and the grain size ranges from 12 nm to 80 nm. The invention has the advantages that the preparation method is a direct method for preparing the layered double hydroxide with high crystallinity, layered structure regularity, wide application range and adjustable particle size. The preparation method comprises the following steps: obtaining highly dispersed metal nanoparticle sol by utilizing the action of colloid mill axial shear force and the sodium borohydride reducibility, and then performing slow oxydrolysis in a hydrothermal system, and the like to generate thenano layered double hydroxide with layered structure regularity and adjustable particle size. The method has the advantages of wide application range, low cost, simple operation and environmental protection.

The invention discloses a halogen substituted 2-(a-hydroxyl amyl) benzoate compound, a preparation method and medicinal application thereof, which belong to the technical field of organic chemical synthesis. The structural formula of the compound which is showed as above has an antimer structure, wherein <R1> represents a halogen atom; n is equal to 1 to 3; and M represents a univalent metallic ion or a bivalent metallic ion or a trivalent metallic ion or an organic base. The compound has the advantages of better activity on preventing and treating cardio-cerebral ischemia diseases, improving cardio-cerebral circulation disturbance and resisting thrombus, and the like.

The invention discloses a catalyst for synthesizing methanol through carbon dioxide hydrogenation, which is composed of oxides, wherein measured by metals, the mole ratio of various metals is as follows: [n(Cu)+n(Zn)+n(MA)]:[n(Al)+n(MB)]=2-15, n(Cu):n(Zn)=0.5-4, n(MA):n(Zn)=0-1, and n(MB):n(Al)=0-9, MA represents monovalent or divalent metal ions, and MB represents trivalent or tetravalent metal ions. The catalyst has the advantages of high carbon dioxide conversion ratio, good methanol selectivity and high methanol yield.

A process for making a fluorinated olefin. The process has the step of dehydrochlorinating a hydrochlorofluorocarbon having at least one hydrogen atom and at least one chlorine atom on adjacent carbon atoms in the presence of a catalytically effective amount of a catalyst composition. The catalyst composition is represented by the following: n wt. % MX/M′O_yF_z, wherein 0<y<1 and 0<z<2 and wherein y+z/2=1; M is an alkali metal ion selected from the group consisting of Li⁺, Na⁺, K⁺, Rb⁺, and Cs⁺; X is a halogen ion selected from the group consisting of F⁻, Cl⁻, Br⁻, and I⁻, M′ is a bivalent metal ion; wherein n is a weight percentage of about 0.05% to about 50% MX based on the total weight of the MX and M′O_yF_z, and wherein y and z are the mole fractions of oxygen and fluorine in M′O_yF_z, respectively. There are also methods for making catalyst compositions.

The invention relates to a divalent metal ion pre-embedded layered vanadium oxide nanometer material as well as a preparation method thereof. The chemical formula of the nanometer material is AxV2O5-y, wherein A is Mg, Ca, Sr or Zn; the MgxV2O5-y has the nanoribbon diameter of 100-1500nm and the length of 5-50 microns or CaxV2O5-y has the nanoribbon diameter of 100-1000nm and the length of 5-50 microns or SrxV2O5-y has the nanoribbon diameter of 100-1000nm and the length of 5-50 microns or ZnxV2O5-y has the nanoribbon diameter of 100-300nm and the length of 5-50 microns or ZnxV2O5-y has the nanoflower diameter of 3-5 microns. The divalent metal ion pre-embedded layered vanadium oxide nanometer material disclosed by the invention has high specific capacity, excellent cycling stability and excellent rate capability and is a potential high-performance commercial zinc ion battery positive electrode material.

A detergent composition comprising; a) a non-phosphorous based builder which is an amino acid based compound or a succinate based compound, b) one or more enzymes which are destabilised by the non-phosphorous containing builder and c) a stabilisation system for the one or more enzymes. The stabilising system comprising one or more divalent metal ion salts and a non-ionic surfactant. Preferably the builder is the tetrasodium salt of glutamic-N,N-diacetic acid and the enzyme comprises protease. The preferred divalent metal ion salts are calcium salts.

This invention relates to novel quinoline-based divalent metal ion chelating ligands of Formula I,

wherein A or B are independently —CR⁷R⁸, or —CH(R⁹)CH(R¹⁰). X is hydrogen, C₁-C₁₀ alkyl; —OH, or —NR¹¹R¹². R¹ to R¹² are various substituents selected to optimize the physicochemical and biological properties such as enzyme binding, tissue penetration, lipophilicity, toxicity, bioavailability, and pharmacokinetics of compounds of Formula 13. R¹ to R¹² may include, but are not limited to hydrogen, alkyl, acyl, hydroxyl, hydroxyalkyl, substituted or unsubstituted aryl, amino, aminoalkyl, alkoxyl, aryloxyl, carboxyl, halogen, alkoxycarbonyl, cyano, and other suitable electron donating or electron withdrawing groups. The compounds of the present invention are useful for inhibiting the activity of viral enzymes responsible for the proliferation of human immunodeficiency virus (HIV).

The invention relates to a detection agent for hemostasis and thrombus belonging to medical clinical detection technical field, in particular to a detection agent for measuring activation partial thromboplastin time (APTT) of blood plasma. The invention is characterized in that the agent is prepared from 0.05-0.5g/L agent solid activator, 20-200mg/L phosphatide, 0.1-10mmol/L divalent metal ion salt, 0.1-0.5g/L stabilizer, 0.1-10g/L polyethylene glycol PEG, 0.05-4.0g/L buffer agent, 2.0-5.0g/L revival agent, while the left is water. The invention provides a high-stability standard agent for meeting APTT measurement, with simple operation, suitable price, short activation time and high sensitivity.

The invention has for its object to provide a preparation method for preparing an anion-exchangeable LDH by decarbonation of a carbonate ion type LDH, which makes sure de carbonation is implemented with safety in a continuous manner while crystal shape, crystal structure and crystallinity are kept intact.

The invention provides a preparation method for preparing an anion-exchangeable, layered double hydroxide wherein a carbonate ion type layered double hydroxide (LDH) having a composition represented by a general formula: Q_xR(OH)_z(CO₃²⁻)_0.5-y/2(X⁻)_y.nH₂O where x is indicative of a numeral range of 1.8≦x≦4.2; z is indicative of 2(x+1); y is indicative of a minimum value of at least 0 that increases to less than 1 when anions (X⁻) remain or a part of anions is introduced; Q is a divalent metal ion; R is a trivalent metal ion; and n is 2±2 is used as a starting material, and y in said general formula increases to a maximum of 1 by substitution of a minus monovalent anion (X⁻¹) at a carbonate ion site thereby implementing substitution, characterized in that the starting material is dispersed in an aqueous solution mixed with a salt containing minus monovalent anions (X⁻) in an amount enough for substitution at the carbonate ion site while said aqueous solution is kept at a pH (hydrogen ion exponent) of greater than 4 to less than 7.

This invention discloses a method for preparing double-metal cyanide complex supported catalyst and its application. The composition is : S-M11a[M(CN)BL1c]íñxM11X2íñy1L2íñy2L3.zH2O, wherein, S is the carrier, and is SiO2, TiO2 or their mixture; M11 is divalent metal ion; M is divalent, trivalent or valency-changeable metal ion; X is halogen anion or analog of halogen anion; L1 is high molecular or low molecular mono-tooth or double-tooth ligand of M; L2 is water-soluble alcohol or cyclic ether; L3 is water-soluble or alcohol-soluble compound, and can be high molecular or low molecular mono-tooth or double-tooth ligand; a and b are positive integers; c is 0 or positive integer; x, y1, y2 and z are 0 or positive numbers. The catalyst is stable in air, and is insensitive to water vapor. The catalyst can be adequately utilized due to supporting, and can be easily removed from reaction products.

The invention discloses a catalyst for synthesizing methanol through CO2 hydrogenation, comprising Cu, Zn, Al, X, halogen and oxygen elements, oxides and halides, wherein the molar ratio of [Cu+Zn+MA] to [Al+Mb] is 2-18; the molar ratio of Cu to Zn is 0.5-5; the molar ratio of MA to [Cu+Zn] is 0-5; the molar ratio of MB to Al is 0-9; the molar ratio of halogen to Al is 0.05-5; MA and MB cannot be 0 at the same time; MA represents a mono-valent or divalent metal ion in X; MB represents a trivalent and/or tetravalent metal ion in X; X is one or a combination of more elements of Li, K, Mg, B, Ga, In, transition metal elements and rare-earth metal elements. The catalyst has the advantages of high carbon dioxide conversion rate, good methanol selectivity and high methanol yield.

The invention relates to a salt-tolerant resistance-reducing agent applied for a shale gas reservoir. The resistance-reducing agent is a biopolymer comprising an acrylamide unit and a propenyl quaternary ammonium salt unit. The weight percent of the acrylamide in the biopolymer is 10%-80%. The propenyl quaternary ammonium salt is one of a propenyl trialkyl ammonium chloride, an alkyl acrylamido propyl trialkyl ammonium chloride or a dialkyl diallyl ammonium chloride. The weight percent of the propenyl quaternary ammonium salt in the biopolymer is 20%-90%, and the molecular weight of the propenyl quaternary ammonium salt is 1*10<6> to 2*10<6>. The resistance-reducing agent provided by the invention can be used as resistance-reducing agents for fracturing flow-back fluid, cavern water and underground produced water, wherein the fracturing flow-back fluid, the cavern water and the underground produced water contain divalent metal ions, and the weight percent resistance-reducing agent provided by the invention for using is 0.05%-0.1%. The resistance-reducing agent provided by the invention has good salt tolerance and resistance-reducing properties, and overcomes problems, of other polypropanamide resistance-reducing agents at present, comprising salt tolerance deficiency in using processes and incapability of being applied for hypersalinity water that comprises Ca<2+> and Mg<2+> at the same time.

A pharmaceutical composition for use as an inhibitor of an enzyme having two divalent metal ions as an active center was found.

It is possible to inhibit the activity of an enzyme by a compound capable of chelating both of the two divalent metal ions.

The invention discloses a layer by layer self-assembly compound nanofiltration membrane based on natural cellulose polyelectrolyte and a preparation method, belonging to the technical field of membrane separation. The preparation method comprises the following steps: firstly, adopting an ultrafiltration membrane as a base membrane for preparing a compound nanofiltration membrane, carrying out chemical modification on the surface of the base membrane to ensure that the surface of the base membrane has a charge property so as to generate static reaction with a polyelectrolyte; and secondly, through alternating depositing anionic and cationic polyelectrolytes, preparing the compound nanofiltration membrane through a layer by layer self-assembly method. According to the preparation method, the adopted cationic polyelectrolyte is a natural cellulose polyelectrolyte; compared with a currently used synthetic polyelectrolyte, the natural cellulose polyelectrolyte is lower in cost, and is an environmental-friendly resource; and the prepared compound nanofiltration membrane containing natural cellulose is good in hydrophilcity and charge performance so that the surface of the membrane is good in pollution resistance; and the compound nanofiltration membrane has a good retaining property for dye molecules such as divalent metal ions such as Ni<2+>, xylenol orange sodium salt, and rhodamine B.

Quite unexpectedly, by suitably modifying the crystal structure of hydrogarnets of the general formula M^II₃Mr^I-III₂(OH)₁₂ (where M^II denotes divalent metal ions, especially alkaline earth metal ions, of Group IIA of the periodic table and M^III denotes trivalent metal ions of Group IIIA of the periodic table, especially aluminum) with suitable amounts of incorporated silicate and/or phosphate, flame retardants having both a higher flame retardant efficiency than such traditional mineral flame retardants as ATH and MDH, and a higher thermal stability than ATH can be produced. It has also been found that synthetic hydrogarnets of the general formula M^II₃Mr^III₂(OH)₁₂(where M^II and M^III are as defined above) having cubic crystal and these synthetic hydrogarnets also show high flame retardant efficiency.

The present invention is based on the discovery that moist heat treated ruminant animal feed compositions comprising a fermentation biomass, have increased amounts of proteinaceous matter that escapes fermentation within the rumen. The ruminant animal feed compositions may further comprise, alone or in combination, one or more of an isolated enzyme, an organic acid, a gluten protein, at least one divalent metal ion and at least one plant extract. The proteinaceous matter may then be digested or metabolized in the post-rumen portions of the ruminant digestive system, thereby providing further increased energy and protein levels for ruminant animals during times of increased productivity. Compositions and methods of manufacture of the compositions of the embodiments of the present disclosure are disclosed.