Agent for activation sector cruor activating-enzyme time (APTT)

Abstract

The invention relates to a detection agent for hemostasis and thrombus belonging to medical clinical detection technical field, in particular to a detection agent for measuring activation partial thromboplastin time (APTT) of blood plasma. The invention is characterized in that the agent is prepared from 0.05-0.5g / L agent solid activator, 20-200mg / L phosphatide, 0.1-10mmol / L divalent metal ion salt, 0.1-0.5g / L stabilizer, 0.1-10g / L polyethylene glycol PEG, 0.05-4.0g / L buffer agent, 2.0-5.0g / L revival agent, while the left is water. The invention provides a high-stability standard agent for meeting APTT measurement, with simple operation, suitable price, short activation time and high sensitivity.

Description

technical field

[0001] The invention relates to a detection reagent for hemostasis and thrombus in medical clinical examination, in particular to a reagent for measuring activated partial thromboplastin time (APTT) in blood plasma. Background technique

[0002] In terms of clinical testing, the detection of hemostasis and thrombus in clinical laboratories is widely used in the diagnosis of bleeding, thrombotic diseases and prethrombotic conditions, efficacy observation, anticoagulant dose monitoring and prognosis analysis. With the development of science and technology and the advancement of basic medical research, people have a deeper understanding of the occurrence and development of hemostasis and thrombus, and their detection methods have become more and more advanced. Wide application in hemostasis detection.

[0003] The activated partial thromboplastin time (APTT) of a plasma sample can be used to determine whether the intrinsic coagulation activity mechanism is in a...