The invention discloses a
phenol separation
coupling catalysis purification method, and relates to the technical field of
fine chemical separation and purification. According to the method, a
metal oxide modified H-ZSM-5
molecular sieve is used as a catalyst, a
coupling reaction and a
separation process are carried out in a catalytic rectifying
tower, and two core processes are synchronously completed: 1, impurities such as
phenol and o-
cresol in raw materials are subjected to a targeted O-
alkylation reaction with
methanol, and the impurities difficult to separate are efficiently converted into an alkylate easy to rectify; and 2, precise
fractionation is synchronously realized, heavy
ether products are extracted and removed from a side line, and target products mainly comprising high-purity 2, 6-
xylenol and 2, 4-
xylenol are obtained in a
tower kettle. Through
integrated design of targeted conversion and synchronous separation, key impurities are removed with
high selectivity, the process is simplified, equipment investment and
energy consumption are reduced, non-target side reactions are avoided, and
high selectivity, high yield, process economy and product quality of target
xylenol are considered.