Medical sterilization ultrasonic coupling agent and preparation method thereof

An ultrasonic coupling agent and disinfectant technology, applied in the directions of pharmaceutical formulations, preparations for in vivo tests, etc., can solve the problems of inability to realize the test, inability to use corrosive and swellable disinfectants, and inability to use disinfection, etc. The effect of reducing the risk of cross-infection of pathogenic bacteria, simple and easy preparation and use, and reliable test results

Inactive Publication Date: 2010-07-14
薛海燕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the medical ultrasonic coupling agents widely used at present do not have the function of disinfection, which leads to the inevitable cross-infection of pathogenic bacteria between the subjects during the process of ultrasonic detection of many people with different health conditions. risk
In order to effectively solve the problem of disinfection in ultrasonic testing, people in the industry have conducted research in different depths. However, due to the particularity of the material of the ultrasonic probe and the requirements for use, people cannot use disinfectants that are corrosive and swellable to plastics and rubber; It is also impossible to use the conventional soaking method for disinfection; it is even more impossible to complete the disinfection operation within a limited interval between subjects.
Several cases of research results on medical ultrasonic coupling agents with disinfection effect have been published. Some of them have unsatisfactory disinfection indicators, some have complex preparation processes, and some have a certain stimulating effect on the skin, so they have not been promoted so far. application
Therefore, the disinfection of ultrasonic probes is still an unresolved problem in the medical field.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Prepare a medical sterilized ultrasonic coupling agent with a total weight of 1000 grams:

[0017] (1) Take 2 grams of cross-linked polyacrylic resin and dissolve it in 800 grams of distilled water, stir gently, and stand still for 10 hours to obtain cross-linked polyacrylic resin liquid A; leave in place;

[0018] (2) Take by weighing 3 grams of p-chloro-m-xylenol and 40 grams of propylene glycol, completely dissolve p-chloro-m-xylenol in the propylene glycol liquid, stir, obtain liquid agent B, and leave in place;

[0019] (3) With the liquid preparation B obtained in step (two), while stirring, add the liquid preparation A obtained in step (one) and continue to stir for 5 minutes, then add 2 grams of sodium hydroxide and 40 grams of glycerol, and then press the total Measure 1000 to make up distilled water until a colorless to light-colored transparent gel is formed under stirring;

[0020] (4) The finished product of the medical disinfection ultrasonic coupling age...

Embodiment 2

[0022] Prepare a medical sterilized ultrasonic coupling agent with a total weight of 1000 grams:

[0023] (1) taking by weighing 8 grams of cross-linked polyacrylic acid resin and being dissolved in 900 grams of distilled water, lightly stirred, and left still for 14 hours to obtain cross-linked polyacrylic acid resin solution A;

[0024] (2) Take by weighing 6 grams of p-chloro-m-xylenol and 80 grams of propylene glycol, completely dissolve p-chloro-m-xylenol in the propylene glycol liquid, stir, obtain liquid agent B, and leave in place;

[0025] (3) with the liquid preparation B obtained in step (two), while stirring, add the liquid preparation A obtained in step (one) and continue to stir for 10 minutes, then add 12 grams of sodium hydroxide and 80 grams of glycerol, and then press the total Add 1000 distilled water until a colorless to light-colored transparent gel is formed under stirring;

[0026] (4) The finished product of the medical disinfection ultrasonic coupling...

Embodiment 3

[0028] Prepare a medical sterilized ultrasonic coupling agent with a total weight of 1000 grams:

[0029] (1) The cross-linked polyacrylic resin that takes 6 grams is dissolved in the distilled water that weight is 850 grams, lightly stirs, and stands still for 12 hours, obtains cross-linked polyacrylic resin liquid A;

[0030] (2) Take by weighing 5 grams of p-chloro-m-xylenol and 60 grams of propylene glycol, completely dissolve p-chloro-m-xylenol in the propylene glycol liquid, stir, obtain liquid agent B, and leave in place;

[0031] (3) With the liquid preparation B obtained in step (two), while stirring, add the liquid preparation A obtained in step (one) and continue to stir for 8 minutes, then add 8 grams of sodium hydroxide and 60 grams of glycerol, and then press the total Add 1000 distilled water until a colorless to light-colored transparent gel is formed under stirring;

[0032] (4) The finished product of the medical disinfection ultrasonic coupling agent obtain...

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PUM

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Abstract

The invention provides a medical sterilization ultrasonic coupling agent and a preparation method thereof. The coupling agent comprises the following main components by the weight percentage: 0.2-0.6% of p-chlor-m-xylenol, 4-8% of propylene glycol, 4-8% of glycerine, 0.3-1.2% of crosslinking polyacrylic acid resin, 0.2-1.2% of sodium hydroxide, and 80-90% of distilled water; the preparation method thereof comprises the steps: (1) dissolving crosslinking polyacrylic acid resin in distilled water to obtain liquor A; (2) dissolving p-chlor-m-xylenol in propylene glycol to obtain liquor B; (3) mixing and stirring the liquor A and liquor B, neutralizing with sodium hydroxide and adding glycerine to obtain the finished product. The invention not only meets the property and functions of medical sterilization ultrasonic coupling agent, but also has efficient and disinfectant effect and causes an ultrasonic probe to always maintain at the disinfectant state, thus completely solving the problem that the ultrasonic probe can not realize the effective disinfection in short time. The invention reduces the risk of the mutual pathogenic bacteria cross-infection among ultrasonic examinees and is beneficial to the health of people.

Description

technical field [0001] The invention relates to a medical ultrasonic coupling agent, in particular to a medical disinfection ultrasonic coupling agent and a preparation method thereof. Background technique [0002] Medical ultrasonic coupling agent is a gel-like preparation that must be used when the human body is used for ultrasonic examination. Its function is to eliminate the air between the ultrasonic probe and the skin of the human body to be examined, strengthen the coupling between the ultrasonic probe and the human skin, so that the sound wave conduction will not be attenuated by the influence of the air, so as to obtain reliable detection results, which is for doctors. provide the basis for correct diagnosis. At present, most of the medical ultrasonic coupling agents widely used do not have the function of disinfection, which leads to the inevitable cross-infection of pathogenic bacteria between the subjects during the process of ultrasonic detection of many people...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/00
Inventor 薛海燕郑丁瑀
Owner 薛海燕
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