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Medicinal composition containing strontium salt
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A technology of composition and strontium salt, which is applied in the field of pharmaceutical composition containing strontium salt, can solve problems such as inability to inhibit bone resorption
Inactive Publication Date: 2012-09-26
FUKANGREN BIO PHARMA
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Vitamin D promotes the deposition of calcium at the site of new bone formation, deposits hydroxyphosphate in the bone, promotes bone calcification, osteoblast function and maturation of bone-like tissue. It is a commonly used clinical bone activator, but it cannot inhibit bone resorption.
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[0019] Pass the prescription amount of strontium ranelate, alfacalcidol, sucrose, L-HPC, and strawberry essence through an 80-mesh sieve, mix well, add 2% PVP-k30 aqueous solution to make a soft material, and granulate with a 24-mesh sieve , dried, granulated, subpackaged.
[0025] Add carmine into the PVP-k30 aqueous solution, stir and dissolve for later use.
[0026] Pass the prescription amount of strontium succinate, alfacalcidol, sucrose, L-HPC, and strawberry essence through 80-mesh sieve respectively, after mixing evenly, add 2% PVP-k30 aqueous solution to make soft material, and granulate with 24-mesh sieve. Dried, granulated, subpackaged.
[0032] Add carmine into the PVP-k30 aqueous solution, stir and dissolve for later use.
[0033] Pass the prescription amount of strontium ranelate, maxacalcitol, sucrose, L-HPC, and sweet orange flavor through a 80-mesh sieve, mix well, add 5% PVP-k30 aqueous solution to make a soft material, and granulate with a 24-mesh sieve , dried, granulated, subpackaged.
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Abstract
The invention relates to a medicinal composition containing strontium salts and vitamin D derivatives. Mixed with auxiliary materials acceptable on pharmacy, the medicinal composition of the invention can be prepared into oral formulations such as particulate granules, common tablets, chewable tablets, dispersible tablets, orally disintegrating tablets, effervescent tablets, buccal tablets, capsules, softgels, sustained release tablets, sustained release capsules, oral solutions, syrups, etc., and can be used to prevent and treat various primary or secondary osteoporosis.
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