Tegasevod maleate oral preparation and its preparation process-for curing intestinal irritability syndrome

Abstract

The present invention relates to an oral medicine preparation for curing intestinal irritability syndrome using constipatino as main sympton-tijaseluo maleate. It is made up by using tijaseluo maleate as active component and adding proper auxiliary material through a certain preparation process, and can be made into various oral dosage forms of tablet, oral disintegrant table, effervescent tablet, capsule, suspension gel and powder preparation, etc.

Description

technical field [0001] The invention relates to a pharmaceutical preparation and a preparation process thereof, in particular to an oral preparation of tegaserod maleate, a medicine for irritable bowel syndrome whose main symptom is treating constipation, and a preparation process thereof. technical background [0002] Irritable bowel syndrome (IBS) is a common disease accompanied by abdominal pain and colon dysfunction, characterized by the absence of inflammation, the cause is unknown, diet, lifestyle factors, infection and unrelated inflammatory conditions have been considered possible At present, there is no specially approved drug and "gold standard therapy" for the treatment of IBS in the world. There are several types of IBS, with constipation being one major type. [0003] Constipation consists of a variety of symptoms, including dry, hard stools, difficulty or incomplete bowel movements, and two or fewer bowel movements a week. According to the pathophysiological ...

AI Technical Summary

Problems solved by technology

The most common adverse events in the tegaserod maleate group were diarrhea, abdominal pain, and dizziness, but the incidence rates were all low (<3%)