Medicinal composition containing ibuprofen sodium salt

A technology of ibuprofen sodium and its composition, which is applied in the field of pharmaceutical compositions containing ibuprofen sodium salt, can solve the problems of affecting the life and work of patients, pain not being cured, brokerage and time wasting, etc.

Inactive Publication Date: 2012-03-28
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In daily life, pain is already a common disease with a high incidence rate. People often adopt traditional treatment,

Method used

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  • Medicinal composition containing ibuprofen sodium salt
  • Medicinal composition containing ibuprofen sodium salt
  • Medicinal composition containing ibuprofen sodium salt

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Example 1 tablet

[0011] Name of raw material

[0012] Process: Take the above-mentioned raw materials, grind them through 80-mesh sieves respectively, and set aside; each auxiliary material respectively pass through 60-mesh sieves, and set aside; except magnesium stearate, take each raw and auxiliary materials respectively, mix them evenly, add appropriate amount of water to make soft materials, 18 mesh granulation, 60 degree fluid bed drying, 24 mesh granulation, adding magnesium stearate, mixing evenly, tableting.

Embodiment 2

[0013] Embodiment 2 capsules

[0014] Name of raw material

[0015] Process: Take the above-mentioned raw materials, grind them through 80-mesh sieves, and set aside; each auxiliary material is respectively passed through 60-mesh sieves, and set aside; except for silicon dioxide and magnesium stearate, take each raw and auxiliary materials, mix them evenly, and add appropriate amount of water Make soft material, granulate with 18 mesh, dry at 60°C, granulate with 24 mesh, add silicon dioxide and magnesium stearate, mix well, fill into empty capsules, and get ready.

Embodiment 3

[0016] Example 3: Chewable tablets

[0017] Name of raw material

Dosage

Sodium ibuprofen dihydrate

100g

Diphenhydramine

25g

lactose

50g

Croscarmellose Sodium

20g

PVP K30

2g

PEG 6000

50g

citric acid

50g

Microcrystalline Cellulose PH-101

200g

Low-substituted hydroxypropyl cellulose

20g

Sucralose

1g

Powdered Orange Flavor

12g

Mannitol

50g

hydrogenated castor oil

5g

Coating powder

Appropriate amount

[0018] Preparation Process:

[0019] 1. PVP is dissolved in an appropriate amount of water;

[0020] 2. Mix lactose, sodium ibuprofen, croscarmellose sodium and 150 grams of microcrystalline cellulose evenly;

[0021] 3. Add PVP aqueous solution to granulate, and dry at 60 degrees; granulate and set aside;

[0022] 4. Take diphenhydramine, 50 grams of microcrystalline cellulose, ma...

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PUM

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Abstract

The invention relates to a medicinal composition containing ibuprofen sodium salt, which is prepared by taking ibuprofen sodium salt and other one or a plurality of medicinal components as active ingredients, and combing the active ingredients with pharmaceutically appropriate auxiliary materials. The medicinal composition can be made into oral preparations, including conventional tablets, dispersible tablets, sustained release tablets, capsules, sustained release capsules, soft capsules, particles, dry suspension, suspension and the like, and used for symptomatic treatment of being antipyretic, antiphlogistic, analgesic and anti-allergic, and improving sleeping.

Description

technical field [0001] The invention relates to a medicinal composition containing ibuprofen sodium salt, which belongs to the technical field of medicine. Background technique [0002] Pain disorders involve a wide range of patients and involve all walks of life in society. There are already hundreds of diseases that produce pain when they are onset. In daily life, pain is already a common disease with a high incidence rate. People often adopt traditional treatment, so that the pain cannot be cured, resulting in waste of management and time, and affecting the life and work of patients. Pain includes a lot of content. According to the statistics of consulting companies, about 55% of adults aged 35-50 are surrounded by various pains, such as benign recurrent headache, shoulder and back pain, waist and leg joint pain, soft tissue pain, neuropathic headache All are common symptoms, and most of the symptoms have pain in various degrees at a certain stage in the course of diseas...

Claims

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Application Information

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IPC IPC(8): A61K31/4402A61K31/192A61K31/137A61K31/167A61K31/485A61K31/135A61P29/00A61P25/04A61P37/08A61P25/20
Inventor 不公告发明人
Owner FUKANGREN BIO PHARMA
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