273results about How to "Improve brain function" patented technology

A non-invasive device and method for stimulation of neural tissue of a patient comprises a power source and at least one pair of electrodes. The power source applies a voltage to the pair of electrodes, and the electrodes extend through a top layer of skin generally adjacent Arnold's nerve. The device can be formed in shape similar to a hearing aid. A second pair of electrodes may also be used, positioned on the skin generally adjacent the auriculotemporal nerve.

This invention provides compositions, methods and process of producing extracts and pure compounds from Xanthoceras sorbifolia. The extract comprises saponins and other constituents including alkaloids, coumarins, saccharides, proteins, polysaccharides, glycosides, tannins, acid, flavonoids and others. The composition can be used for treating cancer and other conditions, such as arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome, angina pectoris, cardiac disorder, coronary heart disease, headache, kidney disorder, and impotence; for improving cerebral functions; or for curing enuresis, frequent micturition, urinary incontinence, dementia, weak intelligence and Alzheimer's disease, autism, brain trauma, Parkinson's, cerebral dysfunctions, and treating arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome, angina pectoris, cardiac disorder, headache, dizziness, kidney disorder. This invention provides compounds of oleanene triterpenoidal saponin in nature with the characteristics that at least one angeloyl group attache to Carbon 21 or/and 22, or/and linked to the sugar. The compounds of the present invention have various pharmaceutical and therapeutic applications.

New 3-substituted 4-(phenyl-N-alkyl)-piperazine and 4-(phenyl-N-alkyl)-piperidine compounds of Formula (1), wherein X N, CH, or C, however X may only be C when the compound comprises a double bond at the dotted line; R₁ is OSO₂CF₃, OSO₂CH₃, SOR₃, SO₂R₃, COR₃, NO₂, or CONHR₃ and when X is CH or C R₁ may also be CF₃, CN, F, Cl, Br, or I; R₂ is a C₁-C₄ alkyl, an allyl, CH₂SCH₃, CH₂CH₂OCH₃, CH₂CH₂CH₂F, CH₂CF₃, 3,3,3-trifluoropropyl, 4,4,4,-trifluorobutyl, or —(CH₂)—R₄; R₃ is a C₁-C₃ alkyl CF₃, or N(R₂)₂; R₄ is a C₃-C₆ cycloalkyl, 2-tetrahydrofurane or 3-tetra-hydrofurane, as well as pharmaceutically acceptable salts thereof are disclosed. Also pharmaceutical compositions comprising the above compounds and methods wherein the above compounds are used for treatment of disorders in the central nervous system are disclosed

The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.

A nanoemulsion composition having enhanced oxidative stability, emulsion stability, and health benefits. The composition may include individual ingredients or a synergistic blend of non-reducing sugars, sugar polyols, medium-chain triglycerides, polysaccharides, polyphenols, phospholipids, chitosan, and alpha-casein, beta-casein, kappa-casein or protein fragments, glycopeptides, phosphopeptides. The composition may optionally be further utilized for the prevention of hypercholesterolemia or bone (and teeth) mineral loss.

The invention discloses a maca functional beverage and a preparation method thereof. The maca functional beverage contains maca, citric acid and water. The preparation method comprises the following steps of crushing maca into fine powder, mixing the maca fine powder and other raw materials, and carrying out homogenization treatment on the mixture. The maca functional beverage has high biologically-active substance content, is conducive to direct absorption of functional and nutritive components by drinkers, realizes complete combination of maca functionality, naturality and safety and is a novel health food and drink having a plurality of functions.

This invention relates to the compound extracted from husk and fruit stem of Xanthoceras Sobifolia and its extracting method and use thereof. Its chemical structure is as below:

A method on its extraction: grinding the husk and fruit stem of Xanthoceras Sobifolia into particles, extracting the particles with solvents, filtrating, reclaiming the solvent and collecting the concentrated solution, passing the collection through macroporous resin, eluting it by solvent, reclaiming the solvent to get the enriched solution, drying the solution to form a brown solid which called total saponins; then dissolving the total saponins in water, extracting by normal butyl alcohol, having the extraction dried to obtain brown powder, chromatographing the powder resolved solution by silica gel column repeatedly, receipting the gradient elution with 100:(35˜60) chloroform:methanol, reclaiming the eluted solution, refining and re-crystallize the left solution, will obtain the white raphide which is the invention compound—Xanthoceraside. It is verified that the compound can be used to make medicine to treat brain diseases and tumors, and to make health food to prevent and cure brain diseases and tumors.

New 3-substituted 4-(phenyl-N-alkyl)-piperazine and 4-(phenyl-N-alkyl)-piperidine compounds of Formula (1), wherein X N, CH, or C, however X may only be C when the compound comprises a double bond at the dotted line; R₁ is OSO₂CF₃, OSO₂CH₃, SOR₃, SO₂R₃, COR₃, NO₂, or CONHR₃ and when X is CH or C R₁ may also be CF₃, CN, F, Cl, Br, or I; R₂ is a C₁-C₄ alkyl, an allyl, CH₂SCH₃, CH₂CH₂OCH₃, CH₂CH₂CH₂F, CH₂CF₃, 3,3,3-trifluoropropyl, 4,4,4,-trifluorobutyl, or —(CH₂)—R₄; R₃ is a C₁-C₃ alkyl CF₃, or N(R₂)₂; R₄ is a C₃-C₆ cycloalkyl, 2-tetrahydrofurane or 3-tetra-hydrofurane, as well as pharmaceutically acceptable salts thereof are disclosed. Also pharmaceutical compositions comprising the above compounds and methods wherein the above compounds are used for treatment of disorders in the central nervous system are disclosed

The invention discloses an aromatic essential oil drug for preventing and treating depression, boosting mood and improving brain function and its composition, which contains main pharmacological active ingredients: vanillin, vanillin salt or isomers of vanillin Any one, two or three mixtures can also be added with other natural spices and native plant essential oils such as rosewood, clove, benzoin essential oils and so on. The medicine of the present invention stimulates the olfactory nerve through the nose and the oral cavity to regulate the olfactory center of the brain and then affect different brain regions, so as to improve brain function, relieve depression, improve mood, and reduce suicide rate, and has quick onset, low concentration, no toxic side effect.

This invention involves a compound that is used for improving brain functioning and/or treatment of brain disorders, made from the following raw materials: (1) one or more medicinal herbs from borax, radix isatidis, honeysuckle, fritillaria cirrhosa D. Don and thunbergii; (2) One or more medicinal herbs from dryobalanops aromatica gaertn. f., calculus bovis, moschus moschiferus L., liquidambar orientalis mill. and gum benzoin; (3) One or more medicinal herbs from cortex phellodendri, coptis chinensis Franch, scutellaria baricalensis, radix gentianae, sophora flavescens; (4) One or more medicinal herbs from baphicacanthus Rhizome and Root, calculus bovis, indigowoad leaf, taraxacum officnala, rhizome of the manyleaf Paris, wild chrysanthemum; and the free selection of (5) Chrysanthemum, folium mori, mint, arctium lappa. This invention also includes the manufacturing method, uses, and the medicinal preparation of the above compounds.

The invention discloses a method for solid fermentation preparing Gamma-aminobutyric acid comprising the following steps firstly filtering red aspergillus from beancurd preserved, putting the red aspergillus MP1104 on oblique plane culture medium and culturing for 7 days to activate the fungus, then transferring the fermentation fungus into culture medium at 30 DEG C, at rotating speed of 150r/min and culturing the activating fungus rocketing bed for 2 says to prepare fermentation seed, optimizing solid fermentation condition and culture medium, at last culturing and preparing GABA on the condition of optimizing culture medium and culture condition. The fermentation raw material is rice and the fungus is red aspergillus. The product of the invention is safe in edibility and also can be used as health care food. The GABA field and purity in the method are high. In optimum fermentation condition and culture medium, the GABA field can be improved from 0.21mg/g to 0.35mg/g and the final purity can be up to 45, and can be prepared continuously in industrialization in low cost.

The invention discloses a production method and an application of high-yield gamma-aminobutyric acid. The conservation number of high-yield gamma-aminobutyric acid (GABA) raffinose enterococcus M1 is CGMCC (China General Microbiological Culture Collection Center) No.5584. The production method comprises the following steps of: separating and selecting strains to obtain an Entercoccusraffinosus TCCC11660 (CGMCCNo. 5584) strain of high-yield gamma-aminobutyric acid; optimizing a fermentation culture medium and fermentation conditions; and carrying out a 10L fermentation tank experiment. The production method has the advantages of cheap raw materials, low production energy consumption, low production cost, good product safety and the like, and industrial production is easy to realize. The strain is applied to production of gamma-aminobutyric acid through glutamic acid fermentation and has good social and economic benefits.

A space is set substantially in a tropical rain forest type environment to activate a human's essential brain region and realize an environment suitable for the human's brain by arranging a device for setting the tropical rain forest type environment based on characteristics of activating human's essential brain region responsive to tropical rain forest type environment information, in a space such as an urban space, a housing space or other living space. The tropical rain forest type environmental information has higher density and higher complexity than those of urban space type environmental information, and includes at least one of auditory information, visual information, and super perceptual information of aerial vibration. The tropical rain forest type environmental information is comfortable for the human with no excessive stress, and is environmental information for effecting prevention and treatment of diseases due to stress by realizing the environment comfortable for the human's brain.

The invention provides a production method of sprouting brown rice nutritious biscuit. Sprouting brown rice is dipped, ground into pulp through a pulping machine, dehydrated, mixed and then steamed into powder. The powder is cooled, dried and then made into sprouting brown rice powder. The sprouting brown rice powder and flour are stirred in a stirring mill. Sugar, oil, powder lot and the like are added and mixed evenly. Pastes are rolled, processed, molded and roasted. Oil is sprayed on the pastes and then the pastes are cooled and packed. The sprouting brown rice serves as main raw material and is mixed with the flour, which realizes nutrition complementation and the produced biscuit contains rich dietary fiber, vitamins and a plurality of trace elements. The biscuit has the advantages of good taste and convenience and is suitable for old and young. The invention develops a new approach of producing nutritious healthy food with the sprouting brown rice.

The invention provides a multi-functional sobering-up food which is made from the major raw materials such as plant extracting fluid or powder with a sobering-up effect, taurine, glucose, vitamin C, vitamin B, vinegar and honey, etc.; the sobering-up food has plenty of effective health protection efficacies, including dispelling alcoholic intoxication, sobering-up, protecting liver, guarding liver, refreshing, restoring consciousness, promoting digestion, appetizing, detoxification, promoting the production of body fluid, reducing blood lipid, lowering cholesterol, preventing cardiovascular and cerebrovascular diseases, delaying aging, etc. The sobering-up food of the invention is especially suitable for people fond of alcoholic beverage, liver disease patients, obesity groups, brainworkers, coronary artery disease patients and numerous adults to eat.

The invention provides a phosphatidylserine-containing composition as well as a preparation method and application thereof. The phosphatidylserine-containing composition contains the following ingredients in parts by weight: 5-40 parts of phosphatidylserine, 10-30 parts of DHA (Docosahexaenoic Acid) algae oil and 10-40 parts of fructus alpiniae oxyphyllae. According to the phosphatidylserine-containing composition provided by the application, a 'PS (phosphatidylserine)-DHA' combination is adopted, the phosphatidylserine (PS), the DHA algae oil and the fructus alpiniae oxyphyllae which are selected and used according to a certain proportion are taken as main raw materials, and through the combination of Chinese traditional and Western medicine, the three drugs have an effective synergistic effect, and have the efficacy of improving memory and enhancing brain functions. According to the preparation method, the phosphatidylserine-containing composition can be prepared into tablets, granules or soft capsules, has the advantages of convenient operation, simple process and the like, and is suitable for volume production and large-scale applications.

The invention relates to full-nutrition formula powder for patients with tumors and a preparation method of the full-nutrition formula powder. Based on the total weight of 100g, the full-nutrition formula powder comprises the following components of 5g-30g of protein, 4g-26g of fat, 30g-80g of carbohydrate, 1g-10g of dietary fibers, 190mg-970mg of vitamins, 1.30g-5.65g of minerals, 1g-10g of a flavoring agent and 0.1g-0.5g of a specificity nutritious supplement, wherein the component of fat comprises 0.1g-2.5g of fish oil; and the specificity nutritious supplement is a mixture of soybean lecithin, a yeast extract, taurine and L-carnitine. The full-nutrition formula powder disclosed by the invention is convenient to carry and can provide comprehensive nutritional support; the full-nutritionformula powder is rich in omega-3 unsaturated fatty acids, especially the ingredient of fish oil provides rich beneficial ingredients of EPA and DHA, and the fish oil and the vegetable oil are combined to form reasonable collocation, so that the body restoring of the patients is promoted.

The invention relates to a mask, and especially relates to a mask having moisturizing and anti-oxidation functions, and its making method. The mask is obtained through using the following raw materials, by weight, 10-20 parts of ginkgo leaf, 15-25 parts of aloe, 5-15 parts of pawpaw, 10-20 parts of chrysanthemum, 5-15 parts of licorice, and 5-15 parts of Lophatherum gracile. The mask having the advantages of scientific and reasonable formula, easily available raw materials, low price, supplementation of abundant natural vitamins for skins, skin pigment removal, prevention of oxidizing damages comprising ultraviolet ray damage, anti-ageing, increase of the skin elasticity, helpfulness for the increase of the immunization and protection effects of skins, restoration of black spots caused by sun exposure and sleep insufficiency, and no anaphylactic reaction, and is an ideal moisturizing and anti-oxidation skin moistening mask.

The invention discloses a medicine for accelerating brain recovery after anesthesia and improving cognition through the nose through the olfactory pathway. Mixture, which can also add other natural spices and native plant essential oils such as lemon essential oil, rosemary essential oil, clove essential oil and neroli essential oil, etc. The medicine, aromatic smell substance or plant essential oil of the present invention stimulates the olfactory nerve through the nose or mouth, regulates the olfactory center of the brain through the olfactory pathway and then affects the secondary olfactory center, so as to refresh the brain, improve the cognitive function of the brain and improve the brain function; moreover These important natural aromatic substances or essential oils directly regulate the instinctive olfactory nerves and play a regulatory role through specific olfactory receptors without any side effects.