1152results about How to "Anti-tumor" patented technology

The invention provides sulfamate serving as an indoleamine-2, 3-dioxygenase inhibitor and a preparation method and application thereof. The structure of the inhibitor is shown in the general formula I, wherein definitions of X, R1, R2, R3, R4, R5 and n are shown in the description and the claim. The invention further discloses the preparation method of the inhibitor. The compound shown in the general formula I can serve as the indoleamine-2, 3-dioxygenase inhibitor and is used for preparing medicine for preventing and/or treating indoleamine-2, 3-dioxygenase mediated diseases. The general formula I is shown in the description.

The invention discloses polygonatum sibiricum lycium barbarum tablet candy and a making method thereof. The polygonatum sibiricum lycium barbarum tablet candy is made of the following raw materials in parts by weight: 1.8-2.2 parts of xylitol, 18-22 parts of polygonatum sibiricum powder, 17-19 parts of lycium barbarum powder, 11-13 parts of poria cocos powder, 12-14 parts of Chinese yam powder, 11-13 parts of date powder, 10-12 parts of walnut powder, 9-11 parts of maca powder, 0.8-1.2 parts of maltodextrin and 0.8-1.2 parts of magnesium stearate. The invention further discloses the making method of the polygonatum sibiricum lycium barbarum tablet candy. The tablet candy is improvement and conditioning function on specific and non-specific immunity functions, and has the functions of preventing tumor, preventing oxidation, reducing the blood pressure, reducing cholesterol, invigorating stomach, enriching blood, moistening lung, reposing, nourishing the kidney and the like.

The invention relates to a novel indoleamine-2,3-dioxygenase (IDO) inhibitor, as well as a preparation method and an application thereof. The inhibitor is compounds of a formula I or pharmaceutically-acceptable salt, solvate, polymorph, enantiomer or racemic mixture thereof, wherein R1 or R2 is independently selected from H, C1-C5 alkyl, halogen and a substituent of a formula II and either of R1 and R2 is the substituent of the formula II; R3 is an aryl group; and n is equal to 0, 1, 2 or 3. Compared with the know IDO inhibitors, the novel IDO inhibitor has significant inhibitory effect on IDO and can be used for treatment of diseases having IDO-mediated tryptophan metabolic pathway pathological features, such as tumors, cancers, Alzheimer's disease, autoimmune diseases, cataract, psychological disorders, depression and/or anxiety. The preparation method of the novel IDO inhibitor has the advantages of being convenient in operation, having mild reaction conditions and reducing solvent consumption and pollution, thereby facilitating industrial production.

The invention provides selenium-enriched konjac rice and a processing method thereof. The selenium-enriched konjac rice is prepared from the following raw materials in percentage by weight: 30-60% of selenium-enriched konjac, 10-30% of rice powder and 20-30% of mung bean powder, wherein the selenium-enriched konjac is selenium-enriched konjac powder or selenium-enriched konjac glucomannan or a mixture of the selenium-enriched konjac powder and the selenium-enriched konjac glucomannan. The production method comprises the steps of mixing the selenium-enriched konjac, the rice powder and the mung bean powder, adding water, stirring the mixture to ensure the moisture content of the mixture to reach 40-45%, extruding the mixture into strips in a screw extruder, granulating, polishing and drying in a fluidized bed until the safe moisture content is 2% and packaging, thus obtaining the selenium-enriched konjac rice. The selenium-enriched konjac rice and the processing method thereof have the following beneficial effects: the selenium-enriched konjac is adopted as the main material and the mung bean is adopted as the auxiliary material to produce the selenium-enriched konjac rice product, so that the product not only has the functions of lowering blood sugar level and blood lipid, resisting tumors, improving immunities, clearing heat and eliminating toxic materials, but also does not have offensive odor or harsh taste of the konjac and has good taste.

The invention relates to health-preserving fungal tea and application thereof. The health-preserving fungal tea is prepared from the raw materials by weight fraction: 10 to 50 percent of edible or medicinal fungal fruit body and 50 to 90 percent of tea. The invention provides health-preserving fungal tea with simple and scientific matching and application thereof in anticancer aspect, so that the nutritive value and pharmacological action of single product are greatly improved. Through scientific matching, the actions of the active substances of the edible or medicinal fungal fruit body and tea are multiplied, so that the nutritive value and pharmacological action are greatly improved. By scientific matching, the fungal tea has unique mouthfeel and flavor, can serve as tea or tea bag to be directly soaked for drinking, can also be prepared into fungal tea beverage, oral liquid, polysaccharide capsule, tablets and the like, and has the efficacies of conditioning yin-yang balance of the functions of five internal organs, improving organism immunity, improving fatigue state, conditioning endocrine dyscrasia, improving blood pressure, blood sugar and blood fat, strengthening body, expelling toxin and protecting liver, preventing disease and radiation, reducing weight and fat, resisting tumor and aging and the like.

The invention discloses a teabag with cordyceps sinensis and mulberry leaves, and a preparation method thereof. The health-care teabag is prepared by taking artificially cultured cordyceps sinensis and mulberry leaves as main components, adding an appropriate quantity of kudzuvine roots, aloes, honeysuckle flowers, chrysanthemums, liquorice and ilex latifolia to the main components and fully utilizing the respective functional nutrient components of the materials for organic collocation. The teabag has the advantages that the teabag can effectively improve the blood circulation of cerebral and peripheral vessels through frequent drinking, has good efficacy in treating hyperlipidemia and hypertension, lowering cholesterol, resisting tumors and aging and enhancing organism immunity, and is a health-care drink suitable for people at different ages.

The invention provides a healthy food capable of postponing aging of women, which is prepared from plant extract with estrogen-like effect, Spirulina, collagen powder and plant polyphenol. The healthy food has the functions on caring skin, strengthening body, improving bone density, lowering blood lipid, improving appetite, preventing cancer, resisting fatigue, improving immunity, and can excite young activity and prevent and postpone aging of middle and aged females.

The invention provides a high-fiber instant asparagus ultramicro-powder beverage and a preparation method thereof. The asparagus ultramicro-powder beverage contains 60% to 75% of asparagus ultramicro-powders, 15% to 20% of stabilizers and 5% to 25% of flavorings. The product is prepared by the following steps: subjecting asparagus processing leftovers to vacuum freeze-drying treatment and micronization, adding stabilizers and flavorings, and mixing thoroughly; and the product is soluble in both cold and hot water. The high-fiber instant asparagus ultramicro-powder beverage is rich in dietary fiber, saponins and flavonoids and has hypolipidemic and anti-tumor functions. The method adopts the vacuum freeze-drying treatment and micronization techniques to retain the effective components of asparagus to the greatest extent and improves dissolution and digestion/absorption of nutrients of the product. The beverage and the preparation method have reasonable designs and abundant raw materials, are favorable to asparagus waste utilization, and increase the economic benefits of asparagus industry.

The invention discloses a fly maggot extractive containing the principal components of water-soluble proteins, and the water-soluble proteins contained in the fly maggot extractive have the mass percentage of 50-70 percent and the molecular weight of 2-16 KDa. The fly maggot extractive not only has obvious inhibiting effect on human promyelocytic leukemia HL-60 cells, human erythroleukemia K562 cells, human liver cancers SMMC-7721, mouse leukemia P388 cells, human lung adenocarcinoma A549 cells, human nasopharyngeal darcinoma CNE cells, human prostatic carcinoma PC3 cells, human cervical carcinoma HeLa in vitro, but also has outstanding inhibiting effect on mouse S180 sarcomas and mouse Heps liver cancer solid tumors, and also has the effect on enhancing the humoral immunity of organisms. The invention also discloses a preparation method of the fly maggot extractive. The preparation method is easy and convenient for operation and control and low in cost and is suitable for industrialized production.

The present invention relates to sea cucumber intestine extract composite soft capsules and a preparation method thereof. The preparation method comprises: adopting sea cucumber intestine produced through fresh sea cucumber processing as a raw material, carrying out slurry grinding, carrying out a heating treatment, cooling, adding two enzymes such as neutral protease and flavor enzyme, and controlling the enzymes to carry out enzymolysis; carrying out centrifugation twice on the enzymolysis solution, adopting a nano-filtration separation technology to carry out a desalting treatment on the collected supernatant, and drying the obtained sea cucumber intestine solution to obtain the sea cucumber intestine powder; and compounding the sea cucumber intestine powder, traditional Chinese medicine extracts such as a medlar extract, a milkvetch root extract, an American ginseng extract, a siraitia grosvenorii extract, a rhodiola rosea extract and a common yam rhizome extract, and auxiliary materials such as soybean oil and beeswax to obtain the sea cucumber intestine extract composite soft capsules. According to the present invention, the preparation method has characteristics of reasonable process and strong operability; and the prepared sea cucumber intestine extract composite soft capsules have characteristics of scientific component and reasonable matching, and further have effects of fatigue resistance, aging resistance, blood fat lowering, anti-tumor, skin benefiting, beautifying, and immunity improving.

The invention belongs to the technical field of food processing, and relates to the technical field of probiotics nutrients, in particular to five-probiotic nutritive powder and a preparation method thereof. The five-probiotic nutritive powder provided by the invention comprises the following raw material components in parts by weight: 2-9 parts of lactobacillus reuteri, 3-9 parts of bifidobacterium lactis, 3-6 parts of bifidobacterium infantis, 2-8 parts of bifidobacterium animalis, 4-11 parts of lactobacillus rhamnosus, 18-38 parts of stachyose, 26-39 parts of fructo-oligosaccharide and 56-86 parts of maltodextrin. The formula of the five-probiotics nutritive powder disclosed by the invention is suitable for babies and middle-aged and old people to use, five-probiotics powder suitable for the babies and the middle-aged and old people to eat can be obtained, the internal environment of the intestinal tracts can be improved, probiotics in the intestinal tracts can be in a dominant position, the propagation and the growth of harmful funguses can be restrained, toxins are degraded, the immunity of the babies and the middle-aged and old people can be enhanced, and the health of human bodies can be promoted.

The invention provides a bagasse-based nano antibacterial fresh-keeping film and a preparation method thereof, and relates to the field of crop straw utilization. The bagasse-based nano antibacterialfresh-keeping film comprises the following components in percentages by weight: 60%-80% of bagasse nanocellulose, 10%-30% of chitin nano crystal whiskers, 1%-5% of cinnamon essential oil, 3%-10% of chitosan, 1%-3% of glycerin, and 1%-3% of sorbitan fatty acid ester. The invention also discloses the preparation method of the bagasse-based nano antibacterial fresh-keeping film. According to the method provided by the invention, the nano antibacterial fresh-keeping film prepared by the method has better strength and gas permeability, the surface of the film can be uniformly moistened and forms awater film, so that external microorganisms are prevented from entering the film; and the added cinnamon essential oil and chitosan can inhibit growth and reproduction of microorganisms, so that shelflife of fruits is prolonged.

The invention discloses a processing technology for instant mushroom strips, which is realized through the following technical scheme: selecting mushroom stems as raw materials; putting the mushroom stems in clean water for soaking, and after being drained, pouring the mushroom stems into a jacketed kettle for boiling; fishing out and draining the mushroom stems; pouring the mushroom stems into a vacuum kneading machine, simultaneously adding auxiliary materials and evenly mixing, and vacuum-pumping and kneading the mushroom stems to be with tastes; frying the mushroom with tastes by using a frying pan till no fluid flows out when a hand is used for pinching the mushroom stems, and taking the mushroom stems out of the frying pan; putting the mushroom stems in a baking house for baking; after being baked, processing the mushroom stems into strips, sheets or threads; and packing and sterilizing to obtain the product. The invention uses the mushroom stems as the raw materials of the instant mushroom strips. The produced instant mushroom strips contain dietary fiber, lentinan, various vitamins and minerals needed by the body, can promote the metabolism of the body and have the functions of resisting viruses and cancers and improving body immunity.

The invention discloses a probiotic composition with an anti-tumor function as well as a preparation method and application thereof. The probiotic composition comprises the following components in mass percent: 60-70% of probiotic dry powder, 20-30% of astragalus root extract powder and 10-20% of asparagus extract powder. Probiotics and traditional Chinese medicines belong to two types of internationally recognized probiotic substances, and the probiotics and the traditional Chinese medicines are similar in mechanism of action and can perfectly complement each other in a concrete use process so as to jointly exert advantages. According to the probiotic composition disclosed by the invention, the probiotics and the traditional Chinese medicines are perfectly combined, and proliferation of the probiotics is promoted by virtue of the probiotic proliferation action of the traditional Chinese medicines so as to enhance the immune function of organisms and inhibit the proliferation of tumor cells, thereby achieving an anti-tumor effect.