Traditional Chinese medicine composition capable of ventilating the lung and relieving asthma and preparation and quality control method thereof

A quality control method and composition technology, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of ineffective control of recurrence, toxic and side effects, etc.

Active Publication Date: 2009-04-01
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine mainly uses antibacterial drugs and hormones for bacteria, but there is no effective drug for infe

Method used

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  • Traditional Chinese medicine composition capable of ventilating the lung and relieving asthma and preparation and quality control method thereof
  • Traditional Chinese medicine composition capable of ventilating the lung and relieving asthma and preparation and quality control method thereof
  • Traditional Chinese medicine composition capable of ventilating the lung and relieving asthma and preparation and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0051] Experimental example 1. the optimal experiment of Chinese medicine group and thing capsule preparation technology of the present invention

[0052] 1. Screening of the amount of water added for water extraction

[0053] Configure 5 parts of medicinal materials, 648.8g each, and divide them into three groups for testing. The first group added 6 times and 4 times the amount of water, the second group added 8 times and 6 times the amount of water, and the third group added 10 times the amount of water. 8 times the amount of water, add 2 times the amount of water to the fourth group of countercurrent circulation extraction process, add 4 times the amount of water to the fifth group of countercurrent circulation extraction process, add 6 times the amount of water to the sixth group of countercurrent circulation extraction process, and use the amount of clear paste after water extraction as an indicator , to determine the amount of water added, the results are shown in Table ...

experiment example 2

[0067] Experimental example 2. The preferred experiment of the processing technology of bitter almond in the Chinese medicine group and thing of the present invention

[0068] The traditional Chinese medicine bitter almond contains the cough-relieving ingredient amygdalin. Under appropriate conditions, such as being exposed to moisture, decocting and soaking in water, the amygdalinase contained in it can easily decompose the amygdalin, thereby reducing or even losing the efficacy of the medicine. Therefore, bitter almonds need to be processed to achieve the purpose of destroying enzymes and protecting glycosides. Due to the current traditional processing methods: water decoction method and stir-frying method are not effective in inactivating enzymes and protecting glycosides, and the quality is difficult to control, so this paper introduces steam hot pressing method and traditional method for comparative experiments to explore better processing methods .

[0069] 1 Instrument...

experiment example 3

[0092] Experimental example 3. Pharmacodynamics experiment

[0093] In order to prove the curative effect of the present invention, we have carried out following pharmacodynamic experiment.

[0094] The drug group of the present invention used in the following pharmacodynamic tests is the capsule prepared according to Example 4;

[0095] Positive control drug: granules prepared by the following method:

[0096] Ephedra 1200g, ginger 1200g, schisandra (made) 150g, roasted licorice 45g

[0097] 1000g made from 627g sucrose and 260g dextrin

[0098] The above four herbs are decocted twice with water, the first time is 3 hours, the second time is 2 hours, the decoction is combined, filtered, the filtrate is concentrated under reduced pressure to a clear paste with a relative density of 1.08 (60°C), and let it cool to At room temperature, add an equal amount of ethanol, stir well, let stand for 24 hours, take the supernatant, recover the ethanol under reduced pressure and concen...

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Abstract

The invention discloses a pharmaceutical composition for ventilating lung and relieving asthma, a preparation method and a quality control method. The pharmaceutical composition comprises the following pharmaceutical raw materials: ephedra herb, raw ginger, cassia twig, bitter apricot seed, Chinese magnoliavine fruit (prepared) and prepared liquoric root, the preparation method is as follows: the five herbal medicines except the bitter apricot seed are decocted by adding water through a countercurrent circulatory extraction process and concentrated to obtain a clear paste after reducing pressure, ethanol is added, then the mixture is stirred evenly and placed staticly, supernatant liquid is taken, the ethanol is recovered, and the concentration is carried out to obtain a thick paste; the bitter apricot seed is arranged in a hot pressure sterilization pot for hot pressure steaming and boiling and then is arranged in a small amount of cold water for soaking instantly after being taken out, an apricot processed product can be obtained by removing seed coats and being dried; the quality control method is as follows: the thin layer identification is carried out on the ephedra herb, the raw ginger and the liquoric root, the content measurement is carried out on ephedrine in the ephedra herb and schizandrin in the Chinese magnoliavine fruit. The pharmaceutical composition has good effects on ventilating lung and relieving asthma.

Description

technical field [0001] The present invention relates to a kind of traditional Chinese medicine composition for relieving lung and relieving asthma and its preparation method and quality control method, especially a kind of capsule for relieving lung and relieving asthma and its preparation method and quality control method, which belongs to traditional Chinese medicine technology field. Background technique [0002] Chronic obstructive pulmonary disease is a common and frequently-occurring disease in internal medicine. It is an important chronic respiratory disease with a large number of patients and a high mortality rate. Due to the protracted disease, it seriously affects the working ability and quality of life of patients. And by the world's general attention. [0003] At present, there is no way to effectively control the development of COPD in the medical field. Seeking an effective method to prevent COPD is an urgent task to be solved by the medical field at home and ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/16A61K9/20A61K9/48A61P11/06A61P11/00G01N30/02G01N30/90
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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