The invention relates to the cotton processing technical field, in particular to a cotton seed, commodity linter and grease raw material co-production process based on the delinting technology of a cylindrical brushing machine. The co-production process is characterized by producing cotton seeds, commodity linters and grease raw materials at the same time by primary processing of materials (fluff). Compared with the prior art, the co-production process has the advantages of simple process flow, short processing route, high production efficiency, low cottonseed crushing ratio, guaranteed seed quality, fewer linter impurities, easy linter cleaning, high commodity linter level, complete waste (photon) skin, convenient hulling, thorough separation between cotton hulls and cotton kernels and high oil yield. In the process, the linter obtained by double brushing is collected, cleaned and packaged respectively, thus ensuring grade quality of the commodity linter.