The invention discloses a fresh cutting processing technology for a radix ampelopsis medicinal material. According to the technology, after the radix ampelopsis medicinal material is harvested, water is seized for cleaning the radix ampelopsis medicinal material while mud is stuck to the surface of the radix ampelopsis medicinal material and the surface of the radix ampelopsis medicinal material is moistened, spreading airing is conducted for 4-6 hours, the radix ampelopsis medicinal material is cut into slices while the radix ampelopsis medicinal material is fresh, the radix ampelopsis medicinal material is packaged in a vacuumized mode after being aired to be dried, and a drying agent is added. According to the fresh cutting processing technology, the medicinal material is washed and processed while being fresh, so that running of water-soluble effective components is avoided, the pollution of microorganisms and worm eggs in soil to the medicinal material is reduced, the processes for medicinal slice production are simplified, the preparing cost is reduced, the medicine quality is ensured, and the clinical effect is improved. By means of implementation and popularization of the fresh cutting processing technology, obvious social significance and economic benefits can be achieved.