The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine oral administration and external application combined preparation. The traditional Chinese medicine oral administration and external application combined preparation comprises an oral administration medicine and an external application medicine, wherein the oral administration medicine contains rhizoma drynariae, angelica sinensis, frankincense, pseudo-ginseng, sangusis draconis, Chinese polyphaga, myrrh, native copper, trogopterus dung, dipsacales, aquilaria sinensis, bitter orange, pawpaw, salvia miltiorrhiza bunge, large leaf gentian root, peach kernel, earthworm, cortex acanthopanacis, radix achyranthis bidentatae, eucommia bark, glaucousback threewingnut root bark, cassia twig, astragalus mongholicus, radix angelicae, rhizoma corydalis, pericarpium citri reticulatae viride, cortex moutan, rhizoma cibotii, bupleurum falcatum, beautiful sweetgum fruit, combined spicebush root, divaricate saposhnikovia root, almond, agastache rugosus, cimicifugae foetidae, betel nut, radix angelicae pubescentis, notopterygium root, Szechuan lovage rhizome, complete blood, madder, coralbean bark, safflower and sinomenium acutum; and the external application medicine contains centipede, chilopod wall gecko, radix angelicae, myrrh, safflower, giant typhonium rhizome, snow mountain wormwood, borneol, glaucousback threewingnut root bark, radix aconiti agrestis, dragon blood, camphor, sundew, complete blood, frankincense, angelica sinensis, rhizoma arisaematis and pinellia ternate. The traditional Chinese medicine oral administration and external application combined preparation of the invention can effectively treat diseases, such as osteoproliferation, and the like, and the disease is difficult to recur after being healed.