The invention discloses a traditional Chinese medicine preparation for treating chronic leukemia. The traditional Chinese medicine preparation comprises the following components by weight: 50-80g of red dates, 20-30g of starworliquoric roott root, 10-20g of parched white peony root, 10-20g of astragalus membranaceus, 10-20g of Japanese honeysuckle stem, 10-20g of tender uncaria rhynchophylla, 10-20g of rhizoma picrorhizae, 10-20g of black radix scrophulariae, 10-20g of towel gourd vegetable sponge, 10-20g of reed rhizome, 8-15g of white muscardine silkworm, 8-12g of realgar, 8-12g of indigo naturalis, 8-12g of liquoric root, 8-12g of poria, 8-12g of redroot gromwell root, 8-15g of Chinese honeylocust fruit, 8-15g of airpotato yam rhizome, 8-15g of donkey-hide glue, 8-12g of tangerine peel and 8-12g of ginger processed pinellia. According to the traditional Chinese medicine preparation disclosed by the invention, various medicines are precise in compatibility and reasonable in prescription, are combined to play roles in clearing heat and removing toxicity, nourishing yin and cooling blood, strengthening body resistance and eliminating evil, benefiting qi and nourishing blood, and activating blood circulation and removing stasis, and can be used for effectively promoting the recovery of blood functions, reducing the side effects of chemotherapy and improving the survival rate of patients suffering from chronic leukemia, so that the traditional Chinese medicine preparation is worthy of clinical promotion and application.