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Traditional Chinese medicine composition capable of resisting brain cancer activity and preparation method and application thereof

A composition and active technology, applied in the field of traditional Chinese medicine compositions with anti-brain cancer activity and preparation thereof, can solve the problems of many impurity components, slow onset of effect, large dosage, etc., and achieve scientific and reasonable proportioning, fast absorption, The effect of low doses

Active Publication Date: 2015-08-19
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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Problems solved by technology

However, the current reported anti-brain cancer drugs have a large dosage, many impurities, and slow onset of action.

Method used

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  • Traditional Chinese medicine composition capable of resisting brain cancer activity and preparation method and application thereof
  • Traditional Chinese medicine composition capable of resisting brain cancer activity and preparation method and application thereof
  • Traditional Chinese medicine composition capable of resisting brain cancer activity and preparation method and application thereof

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preparation example Construction

[0036] 2. the preparation method of the Chinese medicine composition with anti-brain cancer activity of the present invention, it may further comprise the steps:

[0037] (1) Take 10 grams of Radix Aconiti, 15 grams of Shanzi mushroom, 10 grams of Southern Star, 10 grams of Eupatorium, and 10 grams of Alisma by weight, add ethanol with 15 times the volume of the total medicinal material weight, soak for 48 hours, Then ultrasonication, continuous reflux extraction for 3 times, each time for 1 hour, combined extracts, concentrated, the concentrate was put on a macroporous resin column, eluted with water, 20% ethanol to 60% ethanol in sequence, and collected 40 to 50% ethanol eluate , concentrated to obtain the extract;

[0038] (2) Get 3 grams of centipede by parts by weight, continuously reflux extraction with sherwood oil 3 times, each 2 hours, get sherwood oil extract, concentrate and dry, get centipede extract;

[0039] (3) Take the extract obtained in step (1) and the cent...

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Abstract

The invention discloses a traditional Chinese medicine composition capable of resisting brain cancer activity and a preparation method and an application thereof. The traditional Chinese medicine composition is prepared by 10 to 30 parts of giant typhonium rhizome, 15 to 45 parts of edible tulip, 3 to 9 parts of centipede, 10 to 30 parts of arisacma consanguineum, 10 to 30 parts of herba lycopi, and 10 to 30 parts of rhizome alismatis. After proofing by pharmacological experiments, the traditional Chinese medicine composition capable of resisting the brain cancer activity has the advantages that the proportion is scientific and reasonable, the usage of the medicine is strict, and the effects of resisting cancers and detoxifying, dissipating phlegm and removing blood stasis, and the like are realized; the strong killing function on the cells of brain cancer inside and outside the human body is realized, the generation of tumor necrosis factors is promoted, and the immunity of a tumor patient is improved; the safety is high, and the toxic and side effect is low. The preparation method has the advantages that the quality is stable, the content of extracted effective ingredients is high, the operability is high, and the preparation method is suitable for industrial and large-batch production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine composition with anti-brain cancer activity and its preparation method and application. Background technique [0002] Intracranial tumors are also known as brain tumors, whose etiology is still unknown. Tumors originating from the brain, meninges, pituitary gland, cranial nerves, cerebrovascular and embryonic remnants are called primary intracranial tumors. Secondary intracranial tumors are those that metastasize to the intracranial from malignant tumors in other organs and tissues of the body. [0003] A worldwide statistic of the prevalence of intracranial tumors is 40 / 100,000. It shows that the incidence of intracranial tumors is not low, which deserves attention. As far as the incidence rate of systemic tumors is concerned, brain tumors rank fifth (6.31%), only lower than gastric, uterine, breast, and esophageal tumors. In adults, brain tumor...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P35/00A61K35/648
Inventor 程海波周仲瑛沈卫星李柳孙东东徐长亮谭佳妮沈政洁吴东东
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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