The invention discloses a
traditional Chinese medicine compound composition for treating primary
membranous nephropathy and a preparation method thereof. The
traditional Chinese medicine compound composition comprises raw
astragalus membranaceus,
codonopsis pilosula nnannf, rhizoma atractylodis, rhizoma atractylodis macrocephalae, old caulis perllae,
schizonepeta, radix platycodonis, fructus forsythiae, radix pseudostellariae,
eclipta alba,
radix trichosanthis, radix salviae miltiorrhizae, radix actinidiae chinensis, radix curcumae,
ligusticum wallichii, fried
angelica sinensis,
polygonum cuspidatum,
pyrrosia lingua, cortex eucommiae, rhizoma smilacis glabrae and rhizoma dioscoreae nipponicae. According to the
pathogenesis characteristics of the primary
membranous nephropathy, the formula is screened according to the
traditional Chinese medicine theory and clinical experience, the formula is obtained through screening by adopting the core principle of tonifying the
spleen and
kidney, removing poison and nourishing yin and promoting
blood circulation to remove meridian obstruction, the whole formula has the multiple effects of tonifying the
spleen and
kidney, removing poison and nourishing yin, promoting
blood circulation to
remove blood stasis and the like, and meanwhile, the principles of tonifying the
spleen and the
kidney, tonifying the spleen and the kidney and treating slowly through mild tonifying are emphasized. Clinical practice shows that the prescription can significantly reduce 24-hour
urine protein, increase
serum albumin, improve
lipid metabolism disorder and
edema symptoms, improve the PMN
pathological process from multiple dimensions of
inflammation inhibition,
oxidative stress relief,
fibrosis intervention and the like, and is good in
clinical safety.