469results about How to "Safe and non-toxic side effects" patented technology

The invention discloses a baokangling multi-element probiotics oral liquid for treating a digestive system disease and a preparation method of the oral liquid, wherein the oral liquid is comprised of Radix Codonopsis, Atractylodes Rhizoma, Astragalus mongholicus, Rhizoma Dioscoreae, Crataegus pinnatifida, Fructus Hordei Germinatus, Radix Glycyrrhizae, Poria cocos, Ganoderma lucidum, pericarpium citri reticulatae, Fructus citrus sarcodactylis, Fructus Amomi, Cortex Magnoliae Officinalis, Lignum Aquilariae Resinatrm, Cyperus rotundus, Fructus Lycii, Angelica sinensis, Radix Salviae Miltiorrhizae, bletilla striata, unshelled Ascidia, Radix Bupleuri, Radix Paeoniae alba, Corydalis yanhusuo, Radix Glehniae, Polygonatum odoratum, Fructus Schizandrae, Rhizoma Coptidis, peeled Semen Raphani, Semen Lablab Album, Panax notoginseng powder, Fructus Aurantii Immaturus, Radix Aucklandiae, Coix seed, endothelium corneum gigeriae galli, Fructus Corni, lotus seeds and Lindera aggregate. The above traditional Chinese medicinal materials are decocted according to a certain weight ratio and subjected to probiotics fermentation so as to obtain the multi-element probiotics oral liquid. The oral liquid has unique treating effect proven by clinical application. The traditional Chinese medicines are decomposed from macromolecules to micromolecules through biotransformation, so that the effects of absorbing quickly and taking effect instantly are obtained; furthermore, the secondary components and invalid components of the traditional Chinese medicines are converted into the essential nutrient substances incapable of synthetizing by themselves in the human body, so that the curative effect is improved. The application range of the oral liquid is broadened and the quality guarantee period is prolonged.

The invention discloses a corn oligopeptide powder buccal tablet and a preparation method thereof. The corn oligopeptide powder buccal tablet comprises the following components in part by weight: 25-3-5 parts of corn oligopeptide powder, 10-20 parts of hovenia acerba extract, 5-1-5 parts of kudzu root extract, 0.5-5 parts of dried tangerine peel extract, 0.5-5 parts of amomum extract, 0.5-5 parts of ginger extract, 0.5-5 parts of poria extract, 0.1-0.-5 parts of food additive, 1.5-2.-5 parts of mint extract, 35-4-5 parts of white granulated sugar and 0.1-1 part of anti-caking agent. The preparation method comprises the following steps: crushing raw materials, softening the raw materials, granulating by a wet method, drying, sieving, finishing granules, adding the anti-caking agent, tabletting and packaging. The corn oligopeptide powder buccal tablet is scientific and reasonable in formulation, all-around in nutritional and health-care functions of protecting the liver, relieving alcoholism, strengthening the spleen and the stomach and reducing the blood pressure and the blood lipid, good in palatability, safe and non-toxic; and the preparation method is simple and feasible and low in cost.

The invention relates to a large-scale preparation method of fish scale type I collagen peptides. The preparation method comprises the following steps: firstly, performing alkali and acid pretreatment on marine fish scales or freshwater fish scales serving as raw materials to remove impurities, and directly performing directed enzymatic hydrolysis on collagen type I in the fish scales by adopting a one-step biological enzymatic hydrolysis technology to form collagen peptides type I with relatively centralized molecular weight distribution; secondly, separating, purifying and concentrating directed enzyme liquid at the normal temperature by adopting a continuous centrifugal separation and membrane separation combined technology to obtain a fish scale type I collagen peptide solution with purity of not less than 95% and molecular weight of less than 1,000 Dalton; finally, quickly drying finished fish scale type I collagen peptides by adopting a spray-drying technology. The method is simple and feasible in overall process, efficient, energy-saving, short in production cycle and suitable for large-scale production; a fish scale type I collagen peptide product produced by adopting the method is high in purity and good in quality, and the content of peptides with molecular weight of less than 1,000 Dalton is more than 97%.

A genetically recombinant human lysozyme in the form of injection, tablet, capsule, spray dropps and cream for treating the pneumonia, tracheitis, urethritis and cystitis, which are caused by drug-resistant bacteria, is disclosed. It has no toxic by-effect.

The invention provides a nanometer vaccine and a preparation method thereof. A new mannose glycosylated-cationic liposome complex can be used as a vaccine vector and can be applied to the vaccine. In the new liposome complex, neutral phospholipid and mannose are mixed into cationic lipid, so the immunologic adjuvant effect and the antigen-presenting cell targeting property of a liposome are improved, and the cytotoxic effect of the liposome is reduced obviously. The invention provides a novel high-efficiency vaccine vector and an adjuvant which do not have side effects and can improve the immunologic effect of the vaccine obviously.

Disclosed is a medicament for treating throat-blocking abscess, which belongs to the technical field of a traditional Chinese medicine preparation. The medicament is mainly composed of ten kinds of raw herbs of coptis, root of large-flowered skullcap, fructus forsythiae, radix scrophulariae, balloonflower root, isatis root, puffball fruiting body, and the like. The raw herbs are prepared by pharmaceutical equipment into medicaments with dosage forms such as capsules, tablets and oral liquid for standby usage. The medicament in the invention has the efficacy of dispersing wind and clearing heat and resolving phlegm, and has definite therapeutic effect on treating throat-blocking abscess, safety and no toxic or side effect.

A throat-blocking carbuncle treatment plaster belongs to the technical field of a traditional Chinese medicine preparation, is mainly composed of coptis chinensis, scutellaria, forsythia, radix scrophulariae, honeysuckle, chrysanthemum and other 8 raw materials, is prepared by a pharmaceutical equipment instrument into a plaster for external use, has the effects of dispelling wind, clearing heat, confining and reatraining toxicity, and is good in throat-blocking carbuncle treatment effect, safe and free of toxic and side effects.

The invention relates to a traditional Chinese medicine composition for protecting liver, a preparation method and a quality control method thereof. The traditional Chinese medicine composition comprises the traditional Chinese medicine raw materials: 30-200 parts by weight of radix puerariae, 30-200 parts by weight of Semen Hoveniae, 10-100 parts by weight of green tea leaves, 10-90 parts by weight of capillary artemisia, 10-90 parts by weight of asiatic pennywort herb, 10-90 parts by weight of chrysanthemum, 10-90 parts by weight of dried orange peel and 10-90 parts by weight of dried ginger. The traditional Chinese medicine composition not only is simple and easy in preparation method, but also is remarkable in treatment effect and safe, and has no toxic and side effect.

The invention provides a red blood cell lysis solution and a method for lysing red blood cells by using the red blood cell lysis solution. The red blood cell lysis solution comprises the following components by concentration: 0.1 M to 0.5 M of ammonium chloride, 0.001 M to 0.2 M of potassium bicarbonate and 0.001 to 0.05 M of ethylenediamine tetraacetic acid or disodium ethylene diamine tetraacetate. The red blood cell lysis solution provided by the invention has the advantages of a good red blood cell lysis effect, safety to and no toxic and side effect on operators and high lysis efficiency. Formaldehyde is used as a fixing agent, and the red blood cell lysis solution is used together with other components to realize removal of red blood cells in blood; moreover, the solution can be used as a protection agent for a part of non-erythrocyte cells in a blood sample for sample transport, thereby overcoming the disadvantage that remaining cell components in purified blood cannot be stably preserved in the prior art.

The invention relates to an anti-wrinkle compact composition, an emulsion and a preparation method and application thereof. The anti-wrinkle compact composition comprises the following active ingredients: angelica sinensis, panax notoginseng, astragalus membranaceus, saposhnicovia divaricata, gastrodia elata, glossy privet fruits, glycyrrhiza, calendula, albizzia julibrissin, okra, acetyl hexapeptide-8, acetyl octapeptide-3, oligopeptides-3 and dipalmitoyl hydroxyproline. The anti-wrinkle compact composition taking Chinese herbal medicines as main materials and biological small molecular substances as auxiliary materials is safe and free of toxic and side effects. The anti-wrinkle compact composition not only has a strong anti-ageing effect, but also can alleviate various uncomfortable symptoms of skin, improve sensitive skin, smoothen the nutritional channel and the energy channel of the skin and recover elasticity of the skin and improve the brightness of the skin, so that the skin is young, healthy and active. Therefore, the anti-wrinkle compact composition is suitable for preparing skincare products.

The invention relates to a navodon septentrionalis fish-skin antioxidant collagen peptide and use thereof, and the navodon septentrionalis fish-skin antioxidant collagen peptide is characterized in that: the amino acid sequence is Phe-Ile-Gly-Pro-Trp, and the molecular weight is 618.75 Da ((M + H) + 619.63Da) given by ESI (electronic spray ion)-MS (mass spectrum) detection. The preparation method of the navodon septentrionalis fish-skin antioxidant collagen peptide includes navodon septentrionalis fish-skin pretreatment, enzymolysis, ultrafiltration and chromatography and other steps. The prepared antioxidative peptide Phe-Ile-Gly-Pro-Trp has good scavenging effect on DPPH (1,1-diphenyl-2-picryl-hydrazyl) free radical, hydroxyl radical and superoxide anion free radical; at the same time, the Phe-Ile-Gly-Pro-Trp also shows good lipid peroxidation inhibition effect. The Phe-Ile-Gly-Pro-Trp has significant antioxidant activity, and can be used as medicines, health food or food additives.

The invention belongs to the technical field of medical functional dressing and in particular relates to temperature-sensitive glucan-based hydrogel and a preparation method thereof. The temperature-sensitive glucan-based hydrogel takes tannic acid as a crosslinking agent, and is double-network gel formed by temperature-sensitive hydrogel and glucan. The temperature-sensitive glucan-based hydrogelhas temperature-sensitive and antibacterial properties and can realize controllable release of drugs; the drug release is flexibly controlled along partial temperature changes of parts with inflammations; the hydrogel can be used for adsorbing wound percolate and has good biocompatibility and surface lubrication performance; secondary injuries to wounds are not easily caused in a clinical replacement manner; the hydrogel also has biodegradability and does not cause environment pollution.

The invention discloses health care tea. The health care tea comprises the following components in parts by weight: 0-90 parts of tea leaf, 3-50 parts of dogbane leaf, 0-30 parts of ginseng flower, 2-50 parts of pot marigold, 0-70 parts of aizoon stonecrop leaf and 0-50 parts of rose, wherein the tea leaf is of dark tea, green tea, black tea or Tieh-Kuan-Yin. The health care tea has the effects of relieving anxiety and irritability, regulating blood pressure, improving sleep, enhancing immunity and other effects; and simultaneously, all the raw materials belong to materials with homology of medicine and food or the materials which are allowed to use for substitutional tea, and the health care tea has no side effects and can be drunk daily as the substitutional tea for regulating physical functions.

The invention discloses a traditional Chinese medicine composition for treating sequela of cerebral infarction, and belongs to the field of traditional Chinese medicines. Raw materials for preparing effective components of the traditional Chinese medicine composition comprise white chinaure herb, white poria, Chinese clovershrub root, salvia root, medicated leaven, Chinese artichoke, duckweed, jute, tripterospermum, lacca, all-grass of common renanthera, delavay docynia fruit, root of cordateleaf ainsliaea, root of rustyhair raspberry, seed of champion bauhinia and bigleaf fig bark. The traditional Chinese medicine composition is a pure traditional Chinese medicinal preparation, has the functions for benefiting qi for promoting blood circulation and removing obstruction to relieve pains, can be used for symptoms such as stroke, thoracic obstruction, dizziness, hemiplegia, chest distress and heart pains, palpitation and shortness of breath and the like which are caused by qi deficiency and blood stasis, can comprehensively treat multiple cerebral infarction, hemiplegia, aphasia and the like and prevent recurrence of the above symptoms, is an effective drug for treating the sequela of the cerebral infarction and preventing the cerebral infarction at present, and has unique effects for atherosclerotic heart diseases, stenocardia and the like.

The invention aims to provide a method for extracting turtle peptide. The method comprises the following steps of: performing enzymolysis on turtle serving as a raw material by using alkali protease or neutral protease for 1 to 10 hours, wherein the alkali protease is 0.2 to 5 percent of the weight of the raw material turtle and the neutral protease is 0.1 to 4 percent of the weight of the raw material turtle; and heating enzymolysis liquid obtained through enzymolysis to the temperature of between 85 and 120DEG C, deactivating enzyme for 10 to 60 minutes, and performing spray drying to obtain the turtle peptide. The method is easy and convenient to implement, ensures good mouthfeel of the turtle peptide, is low in cost, environment-friendly and high-efficiency, and is suitable for industrial production.

The invention discloses a probiotic enteric capsule for treating intestinal flora disturbance and a capsule body of the probiotic enteric capsule. The probiotic enteric capsule comprises probiotic and auxiliary materials, wherein the auxiliary materials are stachyose, dietary fiber and fructose-oligosaccharide and the mass ratio is (70-85%):(6-10%):(5-11%):(3-10%); and the capsule body comprises sodium alginate, magnesium stearate, gelatin, pectin, glycerin and water. Compared with the prior art, the probiotic enteric capsule has the advantages that the natural probiotic contained in human intestinal tracts is completely adopted, so that the probiotic enteric capsule is safe and free of toxic or side effect, abuse of chemical drugs of antibiotic is avoided and the problem of drug resistance of intestinal harmful bacteria is effectively solved; and the diseases of diarrhea, acute enteritis, chronic enteritis, allergic reaction of food and the like can be effectively prevented and treated, so that the probiotic enteric capsule can be widely applied to the aspect of treatment and prevention of intestinal flora disturbance.

The invention discloses a loquat throat-smoothing sugar, and belongs to the field of food engineering. The loquat throat-smoothing sugar is prepared by processing the following raw materials: 4 to 6 parts of loquat extract, 2 to 4 parts of liquorice extract, 2 to 3 parts of chrysanthemum morifolium ramat extract, 1 to 2 parts of isatis root extract, 1 to 3 parts of lotus leaf extract, 1 to 3 parts of lily extract, 1 to 3 parts of mulberry leaf extract, 1 to 2 parts of mint extract, 35 to 50 parts of starch syrup, and 40 to 50 parts of white granulated sugar. The invention has the beneficial effects that: the loquat throat-smoothing sugar has certain effects of moistening lung, relieving a cough and quenching thirst.

The invention discloses a traditional Chinese medicine for health maintenance, prevention and treatment of respiratory system diseases, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine comprises a medicine mask and a medicine jacket, wherein the active ingredient of the medicine mask is at least prepared from the following traditional Chinese medicines: Ningpo yam rhizome, gambir plant, light yellow sophora root, cassia seed, ternate pinellia, Chinese eaglewood, divaricate saposhnikovia root, milkvetch root, largehead atractylodes rhizome and wrinkled gianthyssop herb; and the active ingredient of the medicine jacket is prepared from the following traditional Chinese medicines: Ningpo yam rhizome, gambir plant, light yellow sophora root, cassia seed, ternate pinellia, Chinese eaglewood, divaricate saposhnikovia root, milkvetch root, largehead atractylodes rhizome, wrinkled gianthyssop herb, white mustard seed, codonopsis pilosula, blackberrylily rhizome, blighted wheat, Chinese magnoliavine fruit, platycodon root, loquat leaf, medicinal evodia fruit, giant typhonium rhizome, manchurian wildginger herb, dried ginger, ephedra herb, common coltsfoot flower, perilla fruit, ginseng, Szechuan lovage rhizome and licorice root. The selected medicinal materials have the effects of relieving exterior syndromes to eliminate pathogenic factors, freeing lung, dredging collaterals, relieving asthma, lowering the adverse flow of qi, eliminating phlegm, relieving cough, invigorating the lung and the kidney, and strengthening vital qi to eliminate pathogenic factors to combine prevention, treatment and health maintenance, so that the traditional Chinese medicine has the advantages of safety and no toxic or side effects, is capable of treating both symptoms and root causes, is low in price and being simple and easy to implement, and is suitable for popularization application in the aspects of clinical treatment, rehabilitation, health maintenance and the like.

The invention discloses tyrosinase inhibitor microemulsion as well as a preparation method and an application thereof, and belongs to the technical fields of foods, medicines and cosmetics. The microemulsion contains a matrix, a tyrosinase inhibitor norartocarpetin and water, wherein the matrix comprises 40%-60% of surface active agent, 20%-45% of cosurfactant and 5%-20% of oil phase; and the microemulsion is prepared by adding raw components according to a certain ratio. The tyrosinase inhibitor microemulsion can be used for overcoming the defects that the solubility of the natural tyrosinase inhibitor norartocarpetin in water is extremely low. The method provided by the invention is simple to operate and can be used for the spontaneous formation of the microemulsion. Nanoscale microemulsion can be formed by using water or an aqueous solution for diluting the tyrosinase inhibitor microemulsion. The obtained microemulsion can be used for effectively resisting enzymatic browning of fruits and vegetables, and preparing whitening cosmetics and other medicines for preventing and treating human hyperpigmentation diseases and melanomas (caused by excessive melanin) needing to inhibit the activity of tyrosinase.

The invention relates to a use of Eurycoma longifolia Jack in preparation of drugs or health products for prevention and/or treatment on high blood sugar diseases The Eurycoma longifolia Jack comprises quassia Eurycoma longifolia Jack or its decoction pieces or extract product. The invention provides an assistant hypoglycemic or hypoglycemic composition. The composition contains a Eurycoma longifolia Jack medical material or its decoction pieces or extract product. The Eurycoma longifolia Jack medical material or its decoction pieces or extract product or preparation can be used for preventing or treating high blood sugar diseases such as diabetes, can produce good treatment effects in short time, can be used as a health food and has high safety. The preparation method provided by the invention has simple processes. Through conventional extraction separation processes, a product with clinical effects is obtained.

The invention discloses all natural ingredient hair dye which comprises dyeing combination drug, pretreating agent and dye mordant. The dyeing combination drug comprises fleece-flower root, prepared rehmannia root, henna, indigofera tinctoria and herb of yerbadetajo. The all natural ingredient hair dye has good hair-dyeing effect and a natural color, the color can not fade after long term washing, and the dyeing recipe is safe and does not have toxic or side effects.

The invention discloses a honey throat-smoothing candy, which belongs to the field of food engineering, and is prepared by processing the following raw materials: 4-6 parts of honey, 1-2 parts of lily bulb extract, 2-4 parts of sophora japonyca flower concrete, 1-2 parts of wolfberry extract, 2-4 parts of licorice extract, 2-3 parts of Hang-zhou chrysanthemum flower extract, 1-2 parts of isatis-root extract, 1-2 parts of mint extract, 35-50 parts of starch syrup, and 40-50 parts of white granulated sugar. The honey throat-smoothing candy has the beneficial effect of having a certain efficacy for disinfecting and diminishing inflammation, and promoting tissue regeneration.

The invention discloses a tyrosinase inhibitormicro-emulsion and a preparation method and an application of the tyrosinase inhibitor micro-emulsion, and belongs to the technical fields of foods, medicines and cosmetics. The micro-emulsion comprises a ground substance, tyrosinase inhibitors including steppogenin and artocarpanone, and water, wherein the ground substance comprises 45%-60% of surfactant, 20%-30% of cosurfactant and 10%-30% of oil phase. The micro-emulsionis prepared from various materials according to certain ratios. The defect of extremely low solubility of the tyrosinase inhibitors including steppogenin and artocarpanone in the water is overcome, the method which is simple in operation and can spontaneously form the micro-emulsion is provided, and the water or an aqueous solution is used for dilution so as to prepare the micro-emulsion with nanoscale grain size. The prepared micro-emulsion can be effectively used for preventing enzymatic browning of fruits and vegetables, preparing skin whitening cosmetics, preventing and treating chromatosis diseases and melanoma of a human body that are caused by excessive melanin, and preparing other medicines requiring inhibition of the tyrosinaseactivity.

The invention discloses a preparation method of a diaphragma juglandis fructus vinegar. The preparation method comprises the following steps: soaking, boiling, cooling through spraying water, performing saccharification and alcoholic fermentation, extracting traditional Chinese herbals by ultrasonic waves, carrying out vinegar fermented grain solid fermentation, spraying vinegar, decocting vinegar, and filling vinegar into bottles. The formula is scientific and reasonable, the nutritional and healthcare functions are comprehensive, moreover, the vinegar has the healthcare functions of tonifying kidney, promoting sperm generation, preventing aging, reliving fatigue, and enhancing the immunity, and meets the requirements of consumers, at the same time, the adopted traditional Chinese herbals have prominent medicinal effects and can be used as food; the raw material resources are wide, and the raw materials are safe, and do not have any side or toxic effect.