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189 results about "Tooth enamel" patented technology

Tooth enamel is one of the four major tissues that make up the tooth in humans and many other animals, including some species of fish. It makes up the normally visible part of the tooth, covering the crown. The other major tissues are dentin, cementum, and dental pulp. It is a very hard, white to off-white, highly mineralised substance that acts as a barrier to protect the tooth but can become susceptible to degradation, especially by acids from food and drink. In rare circumstances enamel fails to form, leaving the underlying dentin exposed on the surface.

Data processing method and system for dental three-dimensional model

The invention discloses a data processing method and system for a dental three-dimensional model, and relates to the technical field of dental three-dimensional modeling, and the method comprises the steps: obtaining initial data of oral cavity scanning, recognizing a tooth type in the initial data, and determining a corresponding tooth surface reflection parameter according to the tooth type; generating scanning parameter combinations for different tooth positions according to the tooth surface reflection parameters and the tooth anatomical structure; tooth point cloud data are collected, and a tooth enamel reflective area and a shadow shielding area are identified; performing light reflection removal processing on the enamel light reflection area, performing data completion on the shadow shielding area, and generating corrected tooth point cloud data; and performing registration fusion on the corrected tooth point cloud data to generate a dental three-dimensional model containing a complete dentition. According to the method, the problem of data missing caused by enamel light reflection and adjacent tooth shielding is solved through a differential scanning strategy and regional data processing aiming at specific optical characteristics of teeth, and automatic construction of a high-quality dental three-dimensional model is realized.
Owner:SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV

Antibacterial synergy-mineralization regulation difunctional nano material as well as preparation method and application thereof

ActiveCN120713863AAntibacterial agentsInorganic phosphorous active ingredientsHydroxypropyltrimethyl ammonium chloride chitosanHard tissue
The invention provides an antibacterial synergy-mineralization regulation difunctional nano material as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. The preparation method comprises the following steps: mixing a disodium hydrogen phosphate solution and a calcium chloride solution to obtain an amorphous calcium phosphate suspension; mixing the amorphous calcium phosphate suspension with a tannic acid solution to obtain an ACP-TA suspension; and finally, mixing the ACP (at) TA suspension and the hydroxypropyl trimethyl ammonium chloride chitosan solution to obtain the bifunctional nano material. A cross-linked shell is formed through the electrostatic adsorption effect of tannic acid and hydroxypropyl trimethyl ammonium chloride chitosan of the antibacterial layer, amorphous calcium phosphate is effectively wrapped, the crystallization process of amorphous calcium phosphate can be remarkably delayed, long-acting release of calcium and phosphorus ions is ensured, the antibacterial function can be effectively achieved, and the service life of the coating is prolonged. An ideal local microenvironment is provided for remineralization of tooth hard tissue, and finally biomimetic mineralization of enamel and deep mineralization plugging of dentinal tubules are achieved.
Owner:GUANGXI MEDICAL UNIVERSITY

SGNH family esterase SH2 screened in Tibet hot spring environment and application of SGNH family esterase SH2

The invention discloses SGNH family esterase SH2 screened in a Tibetan hot spring environment and application of the SGNH family esterase SH2, and belongs to the technical field of gene engineering. According to the invention, a new SGNH family esterase gene is screened from a Tibetan hot spring environment, and recombinant expression is realized in escherichia coli. The recombinant esterase prepared by the invention has the characteristics of thermal stability, salt resistance, organic solvent resistance and the like, can be safely applied to tooth whitening or skin exfoliating products, avoids damage of traditional chemical bleaching agents to enamel, and has important application value in the fields of daily chemicals, medicines, food processing and the like.
Owner:SHENZHEN SIYOMICRO BIO TECH CO LTD +1

Whitening and stain-removing toothpaste and preparation method thereof

The invention relates to whitening and stain-removing toothpaste and a preparation method thereof, and belongs to the technical field of oral care. The toothpaste contains 1.5-2.5 parts of plant zymolyte, 15-25 parts of composite abrasive and the like, and the plant zymolyte is obtained by grinding walnut shell powder, beech, oyster shell and Manny root ice river mud into powder according to the mass ratio of 3: 3: 2: 1 and mixing the powder with compound enzyme liquid for enzymolysis; the composite friction agent and the chelating agent are respectively prepared by mixing substances with specific particle sizes / molecular weights according to a ratio, and also contain a film-forming agent, an enamel repairing component and the like. The preparation method comprises the following steps: preparing plant zymolyte; preparing a mixed solution; and subsequently stirring, degassing and filling. Through cooperation of multiple components, the toothpaste achieves efficient whitening, stain removal and bacteriostasis, has the effects of long-acting stain prevention, enamel repair and oxidation resistance, and solves the problems that traditional toothpaste is not thorough in stain removal, damages enamel and the like.
Owner:SAVITA (GUANGZHOU) HEALTH PHARM CO LTD

Composition with functions of protecting gingiva and repairing enamel and preparation method thereof

The invention relates to a composition with functions of protecting gingiva and repairing enamel and a preparation method of the composition, and belongs to the technical field of oral care. The composition contains a functional additive, a plant compound fermentation extract and the like, the functional additive is a mixture of corn starch, calcium phosphosilicate, hydroxyapatite, ubiquinone, sodium guaiazulene sulfonate, menthol and vitamin E, and the plant compound fermentation extract is obtained by fermenting and purifying honeysuckle flowers, radix polygonati officinalis and dandelions according to a specific proportion. Through the synergistic effect of the fermentation extract and the functional components, the problems that an existing toothpaste body is hardened, the storage stability is poor, the gingival protecting effect is short, and the enamel repairing persistence is insufficient are solved, the gingival protecting effect can be enhanced, the enamel repairing effect can be improved, the stability of the toothpaste body can be optimized, the antibacterial property and the oral mucosa relieving effect are achieved, and the oral cavity repairing effect is achieved. And the preparation process is scientific and reasonable, and is suitable for daily oral care.
Owner:GUANGZHOU HEJIA PHARMACEUTICAL CO LTD

Mild stain-removing and whitening toothpaste containing diatomite and coconut shell carbon and preparation method of mild stain-removing and whitening toothpaste

The invention is applicable to the technical field of toothpaste preparation, and particularly relates to mild stain-removing and whitening toothpaste containing diatomite and coconut shell carbon and a preparation method of the mild stain-removing and whitening toothpaste. The mild stain-removing and whitening toothpaste comprises 9-30% of Changbai Mountain diatomite abrasive, 32-38% of sorbitol, 2-4% of sodium lauroyl silicate, 2-3% of polyethylene glycol 400 and 0.5-2% of coconut shell carbon. The toothpaste is prepared from the following components in percentage by weight: 0.6 to 1 percent of polyvinylpyrrolidone, 0.5 to 0.8 percent of honeysuckle flower extract, 0.5 to 0.7 percent of pseudo-ginseng extract, 0.5 to 0.8 percent of xanthan gum, 0.1 to 0.2 percent of 1, 2-hexanediol, 0.5 to 0.8 percent of essence and water. The diatomite and coconut shell carbon used in the invention are refined natural food-grade raw materials, do not contain chemical components, have low hardness, are suitable for children and sensitive people, and do not damage enamel; the selected Changbai Mountain diatomite and coconut shell carbon with the iodine value of 1500-3000 have a synergistic effect, and the Chinese herbal medicine extract is added to assist in degerming; the adsorption, whitening and deodorizing capabilities of the toothpaste are greatly improved, and the toothpaste can quickly remove stains, whiten and remove bad breath.
Owner:QIANCAOTANG TRADITIONAL CHINESE MEDICINE SCIENCE & TECHNOLOGY RESEARCH INSTITUTE (XIAMEN) CO LTD

Tooth instance segmentation method and device based on anatomic form priori

ActiveCN120953623AImage enhancementImage analysisEntire mouthTooth enamel
The invention discloses a tooth instance segmentation method and device based on anatomic form priori, and belongs to the field of computer vision and artificial intelligence. According to the method, model training is carried out on a CBCT image, a real segmentation mask is processed into a three-classification segmentation mask with enamel as a boundary, the three-classification segmentation mask serves as a supervision signal, a network can directly output a prediction segmentation mask containing tooth boundary information in a reasoning stage, and a detection frame is generated accordingly. And after the detection frame is scaled according to the same proportionality coefficient and projected back to the original image, cutting each tooth to obtain a CBCT image of the single tooth. A loss function based on anatomical morphological prior is introduced into segmentation training of a single tooth CBCT image, and a network is constrained through a self-adaptively extracted morphological skeleton, so that a prediction segmentation mask is kept continuous at a root tip part, and the problem of tooth root segmentation fracture is effectively relieved. According to the method, accurate positioning and high-quality segmentation of the tooth instances are realized, so that the segmentation of the tooth instances in the full-mouth CBCT image is quicker and more accurate.
Owner:GANYUE MEDICAL TECH (CHENGDU) CO LTD

Photocuring dental resin adhesive containing silane coupling agent modified monomer as well as preparation and application of photocuring dental resin adhesive

The invention relates to a light-cured dental resin adhesive containing a silane coupling agent modified monomer as well as preparation and application of the light-cured dental resin adhesive. The dental resin adhesive comprises a resin matrix, an organic polymer and a photoinitiator, wherein the resin matrix consists of methacrylate resin grafted and modified by a silane coupling agent and unmodified methacrylate resin. According to the method, the isocyano group of the silane coupling agent is selected to react with the hydroxyl group on the resin monomer to generate the silane modified grafted resin monomer, and the method is simple, low in equipment requirement and suitable for large-scale production; the obtained dental resin adhesive can be internally covalently cross-linked to enhance the self mechanical property, can also be chemically bonded with a bonding substrate by utilizing a grafted silane coupling agent to improve the interface bonding strength, is especially suitable for being used as an enamel bonding material, and can remarkably improve the service life and the curative effect of a bonded restoration.
Owner:BEIJING UNIV OF CHEM TECH +1

Antimicrobial peptides for remineralization of teeth and prevention of dental caries

Peptides that bind with high affinity to oral cavity surfaces, such as tooth enamel, have been discovered. The peptides exhibit antibacterial and mineralizing abilities, and are useful in many aspects of oral care. The peptides include the amino acid sequence AKRHHGYKRKFH-SpSp. The peptides can be included in oral care compositions such as toothpastes and mouthwashes. The oral care compositions can be used in methods to treat or prevent diseases or conditions induced by acidophilic oral bacteria. Exemplary methods include reducing or preventing tooth decay or demineralization, biofilm or dental plaque formation, and / or bacterial adhesion to a tooth surface; and promoting mineralization of teeth surfaces.
Owner:THE UNIVERSITY OF HONG KONG

Tooth wear evaluation model for evaluating safety of oral product as well as preparation method and application of tooth wear evaluation model

The invention discloses a tooth wear evaluation model for evaluating the safety of oral products and a preparation method and application thereof. The tooth wear evaluation model is at least obtained by grinding and polishing the surface of a tooth model, and the tooth model comprises at least one of an animal enamel block model, an animal dentin block model, a tooth-like material dental film model, a full-mouth animal enamel model and a tooth-like material full-mouth tooth model. According to the tooth wear evaluation model, the wear performance of the oral product can be conveniently tested in vitro.
Owner:GUANGZHOU STARS PULSE CO LTD +1

Tooth patch for repairing tooth hardness and preparation method thereof

PendingCN120788920AImpression capsMedical preparationsHydroxyapatite crystalTooth caries
The invention provides a tooth patch for repairing tooth hardness and a preparation method thereof, the tooth patch comprises a support material and gel, and the gel comprises the following components by mass: 1.5-2 parts of regenerated silicon, 0.5-0.7 part of A200, 1.5-2.5 parts of a thickener, 15-20 parts of a film-forming agent, 4-6 parts of a humectant, and 1-1.5 parts of a gelling agent. The tooth paste can form a hydroxyapatite layer on the tooth surface, repair tooth enamel, promote remineralization of the tooth surface and improve tooth hardness, is alkalescent, and can prevent dental caries; after contacting with saliva, hydroxyapatite crystals can be quickly formed in dentinal tubules to block the dentinal tubules, and the hydrogel can be used for treating tooth sensitivity.
Owner:JIANGXI IVISMILE TECH CO LTD

Diagnostic intraoral scanning and tracking

The present invention relates to diagnostic intraoral scanning and tracking. The present invention relates to methods and apparatus for acquiring, using, and displaying a three-dimensional (3D) volume model of a patient's dental arch. The 3D volume model may include surface information (e.g., color) as well as information about internal structures (e.g., near-infrared (Near-IR) transparency values ​​of internal structures including enamel and dentin).
Owner:ALIGN TECHNOLOGY INC

Preparation method and application of polyethylene glycol functionalized nano capsule-like gel

PendingCN120788971ACosmetic preparationsToilet preparationsMitochondrial electron transportTooth enamel
The invention discloses a preparation method and application of polyethylene glycol functionalized nano capsule-like gel. The preparation method comprises the following steps: (1) extracting a nano capsule-like body; (2) preparing polyethylene glycol functionalized nano capsule-like gel; and (3) applying the polyethylene glycol functionalized nano capsule-like gel to mediating photodynamic tooth bleaching. The polyethylene glycol functionalized nano capsule-like gel is combined with a photodynamic reaction to interfere with an electron transport chain and promote ROS accumulation, and the nano capsule-like gel with a specific photoreaction oxidation function is constructed, so that the nano capsule-like gel can be used for equivalently bleaching teeth with a traditional bleaching agent, and meanwhile, the activity of the nano capsule-like gel is improved. The sensitive risk to tooth essence and the mechanical injury risk to enamel and cementum are remarkably reduced, and the composition can be applied to home care or clinical whitening treatment; and the preparation method is simple, is convenient to use, is mild and non-irritant, is high in biocompatibility, and has a good market application prospect.
Owner:THE STOMATOLOGIAL HOSPITAL OF ZHEJIANG UNIV SCHOOL OF MEDICINE

Enamel repairing toothpaste and preparation method thereof

The invention provides tooth enamel repairing toothpaste and a preparation method thereof, and the tooth enamel repairing toothpaste comprises the following components in percentage by mass: 15-30% of glycerol, 15-30% of glycerol, 5-10% of sodium dodecyl sulfate, 5-10% of sodium dodecyl sulfate, 5-10% of sodium dodecyl sulfate and the balance of deionized water. 10%-25% of hydrated silica; 3%-10% of polyethylene glycol-8; 3%-7% of calcium phosphosilicate; 1%-5% of a surfactant; 0.5%-3% of a binder; 0.05%-0.5% of an antibacterial agent; 0.1%-1.5% of a compound enzyme; the compound enzyme comprises lysozyme, papain and bromelain; the mass ratio of the lysozyme to the papain to the bromelain is 1: (0.4-0.6): (0.4-0.6); and the balance of water. The toothpaste can be used for remarkably improving the repairing effect of enamel and the oral health maintenance capability.
Owner:ZUODIAN IND (HUBEI) CO LTD

Standardized three-dimensional periodontal attachment quantification system and method

PendingCN120732573ADentistryPeriodontal attachmentOral medicine
The invention discloses a standardized three-dimensional periodontal attachment quantification system and method, and relates to the technical field of digital oral medicine, and the method comprises the following steps: calibrating a cementum-enamel boundary, dividing a tooth model into a dental crown and a tooth root, and determining the total surface area of the tooth root; performing sensitivity analysis by using the candidate threshold sequence, and determining an optimal diagnosis threshold in combination with a surface integrity criterion; based on the optimal diagnostic threshold, an absolute adhesion area and a relative adhesion area ratio are calculated and output. The invention provides a quantitative method capable of truly, comprehensively and accurately reflecting the three-dimensional pathological change of the periodontal tissue, and the accuracy of a measurement result is ensured through standardized crown root segmentation and accurate geometric judgment; through data-driven parameter optimization, uncertainty caused by manual intervention is eradicated, and objectivity and repeatability of a measurement result are ensured.
Owner:PEKING UNIV SCHOOL OF STOMATOLOGY

Piezoelectric nano-enzyme material with core-shell structure and application of piezoelectric nano-enzyme material in oral care

The invention discloses a core-shell structure piezoelectric nano-enzyme material and application thereof in oral care, which can generate active oxygen through piezoelectric effect under the action of mechanical stress to realize double effects of tooth whitening and antibiosis. The technology does not need external source energy input, avoids dependence of traditional photocatalysis and chemical bleaching technologies, and is simple and convenient to operate, green and safe. Through in-situ generation of cerium oxide on the surface, the material has dual enzyme activity, effectively balances the antibacterial effect and biological safety, and prevents excessive damage to enamel. In addition, the stability and catalytic efficiency of the material are remarkably improved in a complex oral environment, and the problem of failure of a traditional material is avoided. The technology can be widely applied to oral care products such as toothpaste, mouth wash and antibacterial gel, has remarkable industrialization potential and can bring innovation to the global oral care market.
Owner:HARBIN MEDICAL UNIVERSITY

System and method for determining a dental condition based on the alignment of different image formats

PendingUS20250322521A1Image enhancementImage analysisCementoenamel junctionTooth enamel
A method for determining a dental condition comprising: receiving at least one volumetric image and at least one intra-oral surface scan image of a dental structure of a patient, wherein the dental structure includes at least one of a crown, root, gingiva or bone; aligning the at least one volumetric image with the at least one intra-oral surface scan image; identifying boundaries of the gingiva and the bone within the aligned images; and calculating distances between the identified boundary of the gingiva and cementoenamel junction (CEJ), the identified boundary of the bone and the CEJ, and the identified boundary of the gingiva and the identified boundary of the bone to determine the dental condition.
Owner:DGNCT LLC

Alveolar bone resorption degree detection method, device, equipment and medium

PendingCN121465759AImage enhancementImage analysisExtracted toothTooth enamel
The invention relates to the technical field of oral cavities, and discloses an alveolar bone resorption degree detection method, device and equipment and a medium, oral cavity image data of a patient is obtained, and tooth jaw segmentation data extraction is performed on the oral cavity image data to obtain tooth jaw segmentation data; performing three-dimensional space morphological feature analysis on tooth segmentation data in the tooth jaw segmentation data to obtain tooth coordinate azimuth information; calculating periodontal measurement surface information according to the tooth coordinate azimuth information; extracting enamel boundary line data and alveolar bone boundary line data in the dental jaw segmentation data; calculating an alveolar bone resorption degree result according to the enamel boundary line data, the alveolar bone boundary line data and the periodontal measurement surface information; the alveolar bone resorption degree result is calculated through the boundary line data and the measurement surface information, and the accuracy of the result is improved while the resorption degree is accurately quantified.
Owner:SHENZHEN SAIXI TECHNOLOGY CO LTD

Self-adaptive anti-caries coating as well as preparation method and application thereof

The invention relates to the technical field of oral biological materials, in particular to a self-adaptive anti-caries coating as well as a preparation method and application thereof. The coating is prepared from random and block polymers, and is specifically prepared by polymerizing acid radical-containing functional monomers, phenylboronic acid and derivatives thereof. Construction of the coating depends on specific coordination of a functional group and Ca < 2 + > in enamel, and stable anchoring on the tooth surface is achieved. The core action mechanism is to introduce phenylboronic acid groups to endow the coating with pH sensitive characteristics: in a cariogenic acid environment, biofilm formation is synergistically inhibited through a plurality of mechanisms such as physical barrier, electrostatic repulsion and inhibition of mucoprotein-mediated adhesion. According to the application, the Ca < 2 + > anchoring monomer, phenylboronic acid and the derivative thereof are copolymerized, design is carried out aiming at two key links of protein adsorption and bacterial adhesion, multi-mechanism synergy and environment dynamic response are integrated, and an integrated anti-caries effect from early intervention to long-term protection is realized.
Owner:NANKAI UNIV

Intelligent lamp mirror for washing of children

The invention relates to the technical field of intelligent lamp mirrors, in particular to an intelligent lamp mirror for washing of children, which comprises a mirror module, an inner monitoring camera and a tooth cleaner, and the tooth cleaner is provided with a cleaning groove, a plurality of hardness controllers and a plurality of cleaning brushes. The hardness controller is used for controlling the tall and straight degree of the cleaning brush, so that the friction acting force is dynamically regulated and controlled, stubborn stains are removed, and meanwhile excessive abrasion of enamel is prevented. And on the other hand, the stiffness of the cleaning brush corresponding to the tooth missing position can be reduced through the hardness controller according to the tooth missing condition in the oral cavity of the user, so that the stimulation to gingiva at the tooth missing position is reduced, and the tooth cleaning comfort is improved. The functions of monitoring and cleaning are achieved, and the problems that the cleaning effect is not ideal and teeth and gingiva are damaged due to uncontrollable force of a traditional tooth cleaning tool are solved.
Owner:DONGGUAN LAIMSEN TECH BUILDING MATERIAL CO LTD

Fluoride-free dental varnish composition with NANO-hydroxyapatite and slow-release resin for enhanced enamel remineralization and hypersensitivity management

PendingUS20260183199A1Dentin hypersensitivityTooth enamel
A dental varnish composition for promoting enamel remineralization may comprise nano-hydroxyapatite particles dispersed in a biocompatible resin matrix that forms an adhesive film on tooth enamel. The composition may include a solvent to facilitate uniform dispersion and one or more additives. The resin matrix may be hydrophilic to enhance adhesion and wetting of enamel microstructures. Contact with saliva triggers controlled, gradual release of nano-hydroxyapatite, providing sustained remineralization benefits and protection against demineralization over an extended period. The nano-hydroxyapatite may penetrate enamel microstructures and repair microlesions, while optionally reducing dentin hypersensitivity. The composition may be fluoride-free and formulated with defined weight ratios of resin, particles, and solvent. A method of treatment includes applying the varnish to tooth surfaces, forming the adhesive film, and allowing slow release of nano-hydroxyapatite to strengthen enamel.
Owner:EISENHUTH JENNIFER

A dental sample digestion system and method

The present application relates to a kind of tooth sample digestion system and method, belong to tooth sample detection field, for solving the tooth sample digestion system in prior art in peeling enamel, using diamond line to cut tooth, after cutting, using scalpel and forceps to separate enamel and dentin, and manually grinding enamel, it is difficult to operate, low efficiency Problem;Including: enamel separation mechanism, enamel grinding mechanism and enamel digestion mechanism.Enamel separation mechanism is provided with grinding separation module, enamel on tooth is directly ground down, enamel is stripped down in small granular or powder form, it is convenient for subsequent enamel grinding mechanism to grind it, after grinding, enamel will become more delicate, digestion effect is better, digestion is more complete.Enamel stripping does not need to cut tooth, can realize automatic operation throughout, high efficiency.
Owner:XIAN MEDICAL UNIV

Systems and methods for dental treatment with ekf

PCT designated stageWO2026030297A1Head electrodesDental toolsOral tissueActive agent
This disclosure relates to systems and methods for the electrokinetic (EKF) delivery of therapeutic and cosmetic agents to oral tissues, including but not limited to enamel, dentin, cementum, gingiva, and mucosa. More specifically, it relates to modular, low-current dental treatment platforms configured to deliver active agents across or into oral tissues using flexible electrodes, voltage ramping logic, and optionally insulating or stabilizing structures.
Owner:T33 DENTAL INC

Nisin for inhibiting biofilms

The invention relates to a dental and / or oral care product comprising between 0.0039% and 0.0078% by weight of nisin establishing and / or maintaining a pH of at least 4.5 in situ. Although said rather low nisin concentration does not provide an anti-bacterial effect, it is surprisingly and advantageously capable of maintaining stable pH values of at least 4.5, thereby preventing destruction of a subject's teeth enamel based on enamel demineralization effects at pH below 4.5, and said low nisin concentration advantageously further avoids dysbacteriosis, i.e. the oral microflora remains balanced, thus not leading to an increase of e.g. periodontitis associated bacteria.
Owner:SKYLAB AG

Oral care compositions and methods based on genus Kocuria

The present disclosure relates to compositions and methods for using bacteria (e.g., bacteria from the genus Kocuria) to impart whitening and / or prevention and reduction of color stains to tooth enamel; and oral care compositions for use in such methods. The present disclosure also relates to methods of using the oral care compositions, screening methods, and methods of manufacture.
Owner:COLGATE PALMOLIVE CO

Chinese herbal medicine three-color strip toothpaste and preparation method thereof

The invention belongs to the technical field of daily chemicals, and particularly relates to Chinese herbal medicine three-color strip toothpaste and a preparation method thereof. The Chinese herbal medicine three-color strip toothpaste comprises a faint yellow paste body, a green paste body and a blue paste body, the faint yellow paste body comprises, by mass, 0.1%-2% of chitosan quaternary ammonium salt and 0.1%-1% of an ovateleaf holly bark extract, and the green paste body comprises, by mass, 0.002%-0.15% of sodium copper chlorophyllin and 0.1%-1% of the ovateleaf holly bark extract. The blue paste is prepared from the following components in percentage by mass: 0.03 to 0.15 percent of guaiazulene sodium sulfonate and 0.1 to 1 percent of ovateleaf holly bark extract. According to the Chinese herbal medicine three-color-strip toothpaste and the preparation method thereof provided by the invention, the three-color-strip toothpaste is obtained under the condition that exogenous pigments are not added; the toothpaste can achieve the compound effects of freshening breath, inhibiting dental plaque and oral pathogenic bacteria, resisting inflammation, diminishing swelling, resisting allergy, relieving gingivitis and promoting healing and repairing of recurrent oral ulceration, can promote enamel remineralization and pore repairing, and is high in effect synergy, paste stability and use safety.
Owner:JIANGSU XINGZONGHENG BIOTECHNOLOGY CO LTD

Graphene oxide composite nanocoating, its application and modified dental metal material

The application belongs to the technical field of nanomaterials, and particularly relates to a graphene oxide composite nanocoating, application thereof and modified dental metal material. The obtained graphene oxide composite nanocoating overcomes the problem of easy agglomeration of GO alone, has the advantages of long-term antibacterial property, strong corrosion resistance, low toxicity, good remineralization effect on dental enamel, reduced occurrence of dental demineralization and dental caries, effectively reduced friction between dental metal materials, especially between metal materials for orthodontic treatment, is conducive to the sliding between arch wires and bracket grooves in the orthodontic process, and further conducive to improving the efficiency of aligning and flattening the dental arch in orthodontic treatment and shortening the treatment course. In addition, the application has the characteristics of simple operation, low cost and strong controllability, and provides a simple and universal strategy for preparing dental metal materials with long-term antibacterial property, corrosion resistance, low toxicity, good remineralization effect and low friction.
Owner:SOUTHERN MEDICAL UNIV STOMATOLOGICAL HOSPITAL (GUANGDONG STOMATOLOGICAL HOSPITAL GUANGDONG DENTAL DISEASE PREVENTION & TREATMENT GUIDANCE CENT)

COF heterojunction nanosphere with biomimetic mineralization and antibacterial functions as well as preparation method and application of COF heterojunction nanosphere

The invention relates to the technical field of biomedical materials, in particular to a COF heterojunction nanosphere with biomimetic mineralization and antibacterial functions and a preparation method and application thereof. The preparation method comprises the following steps: mixing a magnolol solution, a 1, 3, 5-tris (4-aminophenyl) benzene solution, a polyvinylpyrrolidone solution, a 2, 5-dimethoxybenzene-1, 4-dicarboxaldehyde solution and acetic acid, so as to obtain COFDMTP-coated Honokiol nanospheres; the preparation method comprises the following steps: mixing 4, 4 '-((2, 5-diformyl-1, 4-phenylene) bis (oxy)) dibutyric acid, COFDMTP (at) Honokiol nanospheres, acetonitrile and an acetic acid solution, and reacting to obtain the COFFPBA (at) Honokiol heterojunction nanospheres. The heterojunction nanosphere provided by the invention not only can promote the mineralization of acid-etched enamel, but also can effectively inhibit the growth of oral bacteria and reduce the occurrence of decayed teeth.
Owner:NORTHWEST UNIVERSITY FOR NATIONALITIES

Application of combined lactobacillus salivarius NHNK-603 in preparation of product for improving tooth color and gingivitis

The invention relates to the technical field of marine microorganisms, in particular to application of lactobacillus salivarius NHNK-603 in preparation of products for improving tooth color and gingivitis. The strain provided by the invention is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC NO: M 2024416. Experiments show; the NHNK-603 has the effects of inhibiting proliferation and biofilm formation of pigment-generating pathogenic bacteria, agglutinating the pigment-generating pathogenic bacteria, inhibiting melanin generation of the pigment-generating pathogenic bacteria, inhibiting hyaluronidase activity of the pathogenic bacteria, promoting growth of gingival fibroblasts, inhibiting gingival cell inflammation and apoptosis induced by the pigment-generating pathogenic bacteria, and inhibiting melanin generation of the pigment-generating pathogenic bacteria. And the product can be used for preparing products for improving tooth color and gingivitis.
Owner:QINGDAO NOVO NUOKANG BIOTECHNOLOGY CO LTD

A pectin-coated volcanic stone oral abrasive loaded with saussurea involucrate extract and a preparation method thereof

The present application relates to the technical field of oral abrasive, in particular to a pectin-coated volcanic stone oral abrasive loaded with saussurea involucrate extract and a preparation method thereof. The oral abrasive comprises volcanic stone particles, saussurea involucrate extract, calcium pectin and an auxiliary agent. The volcanic stone particles serve as a natural porous abrasive, providing strength support and drug loading; the saussurea involucrate extract serves as an active ingredient, providing anti-inflammatory and antibacterial effects; the calcium pectin serves as a controlled-release agent and coating material, forming a gel network with calcium ions to control the release of the saussurea involucrate extract and wrapping the volcanic stone particles to form a flexible contact, buffering the direct friction of the abrasive on the tooth enamel; the components synergistically achieve the integrated effects of "physical cleaning-gel protection-traditional Chinese medicine treatment", ensuring the cleaning effect while reducing the dentin abrasion value, reducing the damage to the tooth enamel and effectively inhibiting oral pathogenic bacteria. The preparation method of the oral abrasive is simple, low in cost and has a broad application prospect.
Owner:HOSPITAL OF STOMATOLOGY CHINA MEDICAL UNIV