7 results about "Biodegradable scaffold" patented technology

Medical stent designs are disclosed. An example stent includes a tubular scaffold having a proximal end and a distal end. The tubular scaffold includes a first filament extending between the proximal end and the distal end, the first filament including a first biodegradable region positioned adjacent to a second biodegradable region. Further, the first biodegradable region includes a first biodegradable material, the first biodegradable material having a first rate of degradation. The second biodegradable region includes a second biodegradable material, the second biodegradable material having a second rate of degradation, wherein the first rate of degradation is different from the second rate of degradation.

A biodegradable scaffold and methods of vessel preparation and drug delivery using the biodegradable scaffold are described. The biodegradable scaffold may be used to treat vessel dissection, restore vessel elasticity, and to provide long term release of drugs to prevent smooth muscle cell proliferation.

This invention relates to the development of a biodegradable scaffold containing growth factor and antibiotic loaded nanoparticulate systems with the aim of enabling the regeneration of the pulp-dentin complex of immature permanent teeth with necrotic pulp damaged due to infection, trauma, or developmental anomalies.

A synthetic rotator cuff repair scaffold / patch system fabricated from citrate-based materials is provided. The biodegradable scaffold / patch system includes (i) a citrate component and / or other carboxylic acid components, (ii) a polyol, and (iii) particulate inorganic material. The patch system includes a patch that defines a patch thickness and may define a porosity gradient across the patch thickness.

This invention belongs to the field of bone replacement material technology, specifically relating to a porous biodegradable bone replacement scaffold and its preparation method. The porous biodegradable scaffold of this invention consists of pillars, each pillar having an outer shell and a core. The outer shell comprises ZnO, and the core comprises Zn. The porous biodegradable bone replacement scaffold of this invention has a nano- to millimeter-level hierarchical pore structure, which is more similar to the structure of human bone. Furthermore, its degradation performance, antibacterial properties, and biocompatibility are superior to existing biodegradable metallic bone implant materials (zinc and its alloys), which helps promote osteogenic differentiation.

Disclosed herein are compositions of biodegradable scaffolds combined with mesenchymal stem cells and methods of use thereof for the regeneration of cranial sutures and treatment of craniosynostosis, which can help reverse increased intracranial pressure and skull and neurocognitive abnormalities.

A synthetic rotator cuff repair scaffold / patch system fabricated from citrate-based materials is provided. The biodegradable scaffold / patch system includes (i) a citrate component and / or other carboxylic acid components, (ii) a polyol, and (iii) particulate inorganic material. The patch system includes a patch that defines a patch thickness and may define a porosity gradient across the patch thickness.