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36 results about "Tooth Tissue" patented technology

Your teeth are composed of four dental tissues. Three of them—enamel, dentin and cementum—are hard tissues. The fourth tissue—pulp, or the center of the tooth that contains nerves, blood vessels and connective tissue—is a soft, or non-calcified, tissue.

Tooth intelligent segmentation and parameterized bionic reconstruction method fusing multi-modal data

PendingCN120472096AImage enhancementImage analysisTooth TissueBiomedicine
The invention discloses a tooth intelligent segmentation and parameterized bionic reconstruction method fusing multi-modal data, and belongs to the field of artificial intelligence and computer-aided biomedical engineering. The method comprises a CBCT intelligent segmentation module, an intraoral scanning intelligent segmentation module, an internal tissue segmentation module, a point cloud generation registration module and a parameterized bionic reconstruction module. The point cloud generation registration module further comprises a point cloud generation sub-module and a point cloud registration sub-module; the parameterized bionic reconstruction module further comprises a dentin reconstruction sub-module, a cancellous bone reconstruction sub-module and a gingival reconstruction sub-module. The invention aims to realize tooth semantic segmentation, point cloud reconstruction and parameterized bionic modeling of an organization structure under cross-modal data fusion, and provides high-precision bionic internal structure information for teeth in combination with an artificial intelligence model and parameterized modeling.
Owner:GUILIN UNIV OF ELECTRONIC TECH

Oral care apparatus

Proposed are schemes, solutions, concepts, designs, methods and systems pertaining to aiding and / or improving oral care apparatus having cleaning elements that are adapted, in use, to engage dental tissue of the user. Embodiments propose that, based on light reflected from a surface of the oral cavity during use, an indication of positioning with respect to a tooth surface or gum tissue of the user may be determined. That is, it may be determined whether a cleaning element is positioned at a tooth surface or gum tissue of the user by analyzing light reflected from a surface of the oral cavity.
Owner:KONINKLIJKE PHILIPS NV

Oral treatment planning system driven by big data

The invention relates to the technical field of medical data processing, and comprises a big data driven oral treatment planning system, which comprises a tooth form data acquisition module, a microcrack identification module, an occlusion stress data processing module, a restoration form optimization module and a customized treatment recommendation module. According to the method, the reliability of micro-crack identification is improved by acquiring the tooth surface morphology point cloud data, accurately depicting micro details of the tooth surface morphology and screening areas with violent curvature change and continuous space, the areas with large local stress are identified by analyzing the stress conditions of tooth tip staggered contact points in different occlusion states, and the accuracy of micro-crack identification is improved. The contact point form of the local abnormal stress area is adjusted, the long-term stability of the restoration is optimized, the adaptability of a restoration material and tooth tissue under different stress conditions is analyzed, whether the restoration form meets the long-term stress balance requirement or not is comprehensively judged, and the long-term stability and occlusion adaptability of the restoration are ensured.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV

Dental drilling hardness real-time monitoring method based on vibration signal analysis and dental hardness sensor

The invention relates to a dental drilling hardness real-time monitoring method based on vibration signal analysis and a dental hardness sensor. The dental drilling hardness real-time monitoring method comprises the following steps: acquiring a three-dimensional vibration displacement signal; after filtering and multi-dimensional feature extraction, obtaining a vibration feature vector representing the mechanical impedance of the tooth body; inputting the hardness index and the vibration displacement into a trained machine learning model, and mapping and outputting the hardness index and the vibration displacement of the current drilling area in real time; packaging with a timestamp, and serializing and storing as a traceable historical record; the system continuously presents hardness change in a dynamic waveform and a color gradient, and prompts when detecting that the hardness changes suddenly or crosses a boundary. Compared with the prior art, the method has the advantages that the three-dimensional micro-vibration signal of the drill bit can be converted into the digital fingerprint of the mechanical impedance of the tooth tissue in real time, and a visualization-reminding closed loop is driven by the hardness index flow synchronized with the timestamp, so that the drilling hardness in-situ sensing is realized.
Owner:SOUTHEAST UNIV

Magnifier for observing visual field of intraoral lingual palatal side oral clinical operation

The invention discloses a magnifying lens for visual field observation of intraoral lingual palatal side oral clinical operation, the magnifying lens comprises a lens body, a connecting piece and an occlusal pad, one end of the connecting piece is connected with the lens body, the other end of the connecting piece is connected with the occlusal pad, and the connecting piece has flexibility and can be kept shaped after being bent under external force. The endoscope body is fixed in the mouth through the occlusal pad and does not need to be held by a doctor during use, the doctor can conveniently conduct treatment operation with two hands, meanwhile, the angle in the mouth of the endoscope body can be adjusted by bending the connecting piece, a view blind area in the mouth can be better observed, and therefore in clinical treatment of the oral cavity, the endoscope is convenient to use. The oral magnifier is simple in structure and convenient to use, tooth tissue operation can be more accurately performed on part of visual blind areas, discomfort of a patient after long-time mouth opening during treatment is relieved while the oral magnifier is fixed through the occlusal pad, and the risk that soft tissue injury possibly exists due to change of the mouth opening degree of the patient is reduced.
Owner:SICHUAN UNIV

Detecting the distance of a probe to the pulp of a tooth

ActiveCN116634964BDentinTooth Tissue
A method and apparatus for detecting a distance of a probe contacting a tooth surface to a pulp of a tooth by determining an indication of a thickness of a dentin of the tooth is provided. The method includes illuminating tooth tissue of the tooth with the probe and then receiving data indicative of scattered light from the tooth tissue. A spectrum of the scattered light is then acquired and analyzed to further acquire a spectral analysis result. An indication of the thickness of the dentin of the tooth is then determined based on the spectral analysis result. The method can help prevent accidental exposure of the pulp during dental treatments such as drilling.
Owner:KONINKLIJKE PHILIPS NV

Negative pressure device attached to tooth tissue

InactiveCN120643330ASurgerySomatoscopeTooth TissueBiomedical engineering
The invention discloses a negative pressure device attached to tooth tissue. The negative pressure device comprises a suction sliding plate and an attachment block, the lower end of the attachment block is slidably connected with a suction sliding plate; the lower end of the front end of the attachment block is provided with a suction sliding groove which is in sliding connection with a suction sliding plate. Attached sliding grooves are formed in the two sides of the upper end of the suction sliding groove in a penetrating mode and slidably connected with attached sliding plates, a plurality of limiting grooves are formed in an array in the suction sliding groove, and a removing sliding groove is formed in the middle in a front-back penetrating mode. A limiting plate is arranged in the middle of the front end of the attached sliding plate; the front end of the limiting plate is provided with a limiting block movably connected with the limiting groove; the suction slide plate can be pushed to enable the attachment slide plate to clamp tooth tissue, and the suction slide plate can be pulled to release clamping, so that stable attachment is realized, suction positions can be quickly switched in an operation process, and the continuity of the operation is ensured.
Owner:SHAOXING DENTAL HOSPITAL

Method for manufacturing a dental grinding slice of a specified image section in micro-CT

ActiveCN115307989BPreparing sample for investigationExtracted toothTooth Tissue
The present invention relates to the field of imaging technology, and discloses a method for fabricating a tooth grinding slice of a specified image section in micro-CT. The method includes the following steps: preserving freshly extracted teeth in a 0.5% thymol solution; selecting target teeth to take micro-CT; importing the Dicom format data of the micro-CT into medical image processing software to three-dimensionally reconstruct a 3D tooth model. In this example, the tomographic image in the lower left corner of the attached figure is selected as an example; the method for fabricating a tooth grinding slice of a specified image section in micro-CT according to the present invention utilizes 3D modeling technology and 3D printing technology to fabricate a 3D printed guide plate for guiding the cutting direction of dental tissue, realizing the accurate transfer from the micro-CT image section to the actual dental tissue surface. By combining the tooth grinding slice fabrication technology with the 3D printed guide plate, the tooth tissue slice is selectively polished in a single direction, effectively protecting the target tissue surface and realizing the accurate transfer from the micro-CT image section to the ultra-thin tooth grinding slice.
Owner:SHANGHAI TONGJI STOMATOLOGY HOSPITAL (TONGJI UNIVERSITY AFFILIATED STOMATOLOGY HOSPITAL)

An erbium laser-activated irrigation-assisted positioning crown device and its manufacturing method

The present invention discloses an erbium laser-activated irrigation-assisted positioning crown device and a manufacturing method thereof. The erbium laser-activated irrigation-assisted positioning crown device includes: a crown base for cooperating and connecting with a tooth and forming a complete seal with the tooth tissue; a laser interface provided at the top of the crown base and adapted to the structure of an erbium laser for connecting the erbium laser; an inlet connecting pipe provided at the side of the crown base for connecting an inlet pipe; and an outlet connecting pipe provided at the side of the crown base for connecting an outlet pipe. The present invention can prevent liquid splashing, liberate the hands of medical staff, and enhance the treatment effect of erbium laser-activated irrigation.
Owner:BEIJING TOCHIJIHE MEDICAL TECHNOLOGY CO LTD

Snapshot tooth optical parameter measurement and calculation method

The invention discloses a snapshot type tooth optical parameter measurement and calculation method. The method comprises the following steps: controlling a snapshot type optical acquisition unit to synchronously acquire an original optical image data set containing multiple types of light components; pixel-level spectral features are extracted, and spectral response intervals of different tooth tissues are distinguished; dividing and analyzing sub-regions in combination with an anatomical structure, constructing an optical characteristic initial analysis matrix, and obtaining spectral attenuation characteristic data; matching with a preset sample library to obtain a preliminary optical parameter estimation value; and introducing ambient light and equipment imaging deviation factor dynamic correction, and constructing an overall parameter distribution model to output core optical parameters. According to the method, tooth contact is not needed, the efficiency is improved through synchronous imaging, the defects of fuzzy tissue differentiation and poor interference resistance of a traditional method are overcome through spectrum-anatomical structure combined analysis and a dynamic correction mechanism, output parameters are accurate and stable, and the method is suitable for oral clinical diagnosis and tooth restoration scenes.
Owner:SICHUAN UNIV

Tooth tissue external fixing sleeve for preventing subfissure of teeth from splitting

ActiveCN121015330ADental splintsTeeth cappingCrack toothOral problems
The invention relates to the technical field of oral cavity medical instruments, and provides a tooth tissue outer fixing sleeve for preventing subfissure of teeth from splitting, the tooth tissue outer fixing sleeve comprises an elastic unit, two lock catch units and a fixing band, the two sides of the elastic unit are connected with the lock catch units respectively, the lock catch units are provided with one-way through holes, and the fixing band is provided with one-way through holes. The fixing band can penetrate through the one-way penetrating holes in one direction, the two ends of the fixing band penetrate through the one-way penetrating holes in the lock catch units respectively, the fixing band, the two lock catch units and the elastic unit form an annular structure, and the lock catch units can be fixed to the surfaces of teeth in an adhering mode. And an interval space is arranged between the two lock catch units. By means of the technical scheme, the problems that in the prior art, a hidden crack tooth fixing mode is troublesome to operate and difficult to clean are solved.
Owner:BEIJING STOMATOLOGY HOSPITAL CAPITAL MEDICAL UNIV

A method for culturing the tooth germs of the mandibular first premolar

ActiveCN119214080BGrowth substratesCulture mediaBiotechnologyTooth Tissue
The application discloses a tissue culture method of Pterospermum acerifolium, which comprises the following steps: (1) preparation of explants, (2) tissue culture induction medium, (4) subculture, (5) rooting culture, and (6) transplanting of tissue culture seedlings. Through a series of processes such as disinfection, basic culture, proliferation culture and rooting culture of the tissue culture seedlings of Pterospermum acerifolium, a large number of Pterospermum acerifolium tissue culture seedlings with stable quality can be quickly obtained.
Owner:ZHANGZHOU INST OF AGRI SCI

Combined crown cutting guide plate and design and preparation method thereof

The invention relates to the field of dental instruments, in particular to a combined crown cutting guide plate and a design and preparation method thereof. The combined crown cutting guide plate comprises a public main guide plate and at least one cutting sub-guide plate detachably connected with the public main guide plate. The common main guide plate comprises abutment retention plates arranged on the two sides, and a first connecting rod and a second connecting rod which are connected with the abutment retention plates on the two sides; a crown cutting working area is defined by the first connecting rod, the second connecting rod and the abutment tooth retention plate; the cut-off guide plate is installed between the first connecting rod and the second connecting rod, and the cut-off guide plate is provided with an irregular cut-off face which is attached to a to-be-cut crown tooth body and enables the to-be-cut crown tooth body to be exposed. Compared with the prior art, the combined crown cutting guide plate disclosed by the invention can meet the requirement that redundant tooth tissues outside a common insertion path are cut off in the tooth preparation process of teeth with relatively large inclination in the long axis direction of the teeth, so that the common insertion path is obtained, and the requirement of minimally invasive tooth preparation is met as much as possible.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Photocuring dental restoration regeneration material and preparation method thereof

The invention provides a light-cured dental restoration and regeneration material and a preparation method of the light-cured dental restoration and regeneration material. The antibacterial coating is prepared from the following raw materials: 20 to 30 parts of bisphenol A-glycidyl methacrylate, 10 to 20 parts of carbamate dimethacrylate, 15 to 25 parts of diluent, 30 to 45 parts of mesoporous mineralized boron nitride-bioglass composite filler, 5 to 10 parts of nano-hydroxyapatite, 3 to 8 parts of biquaternary ammonium salt-tea polyphenol synergistic antibacterial complex, 1 to 3 parts of photoinitiator and 3 to 8 parts of flexibilizer. 2-5 parts of a thixotropic regulator and 0.1-0.5 part of a coloring agent. The photocuring dental restoration regeneration material has the technical effects of high strength, good toughness, good antibacterial activity, capability of inducing tooth remineralization, tight combination with tooth tissues, high photocuring efficiency, convenience in operation and excellent aesthetic degree.
Owner:YANGTZE DELTA REGION INST OF TSINGHUA UNIV ZHEJIANG

A method for manufacturing and using a personalized precise tooth guide plate

The application provides a manufacturing method and a using method of a personalized precise tooth-removing guide plate, and belongs to the technical field of oral micro-invasive repair. The manufacturing method comprises the following steps: obtaining a digital impression or model of an initial state dentition and processing the digital impression or model by using a three-dimensional design software to obtain a digital diagnostic wax pattern; comparing and fitting the digital impression or model of the initial state dentition with the digital diagnostic wax pattern to design a personalized precise tooth-removing guide plate digital model; and outputting data of the personalized precise tooth-removing guide plate and 3D printing the personalized precise tooth-removing guide plate. The application is aimed at the actual situation that teeth need to be restored in appearance and function by improving the tooth shape in the case of lip (tongue) inclination or ectopia, mesial (distal) twist and incisal (occlusal) elongation. The personalized precise tooth-removing guide plate takes the expected repair effect as the target, can realize accurate evaluation before treatment and indicate the actual tooth tissue amount that needs to be removed before the in-mouth manufacturing of a diagnostic veneer, and improves the clinical diagnosis and treatment level and the patient satisfaction.
Owner:WUHAN UNIV

Composition for air polishing the surface of hard dental tissues

PendingFR3166287A1Cosmetic preparationsToilet preparationsAir polishingSodium fumarate
Composition for air polishing the surface of hard dental tissues. The present invention relates to a composition (1) for air polishing the surface of hard dental tissues, comprising at least: - a first abrasive powder suitable for polishing hard dental tissues, the first powder being present in the composition at a mass content of between 90% and 99.5%, and - a second powder of at least one anti-caking agent, different from the first powder, comprising at least one sodium stearyl fumarate powder present in the composition at a mass content of between 0.5% and 5% and having a D50 particle size of between 5 µm and 200 µm, for example between 10 µm and 80 µm, at least 50% of the constituent particles of the second powder having a smallest dimension greater than 100 nm. Figure for the abstract: Fig. 1.
Owner:PROD DENTAIRES PIERRE ROLLAND

Dental pulp nerve cell filling paste and preparation method thereof

The invention relates to the technical field of medical instruments, in particular to dental pulp nerve cell filling paste and a preparation method thereof, and the filling paste comprises the following components: 8-12% of an inorganic filler, 12-18% of an antibacterial filler, 5-8% of slow-release antibiotic microspheres, 8-12% of an nHA-Col collagen composite material, 1-3% of a traditional Chinese medicine extract, and the balance of a liquid agent. According to the technical scheme, growth and reproduction of pathogenic microorganisms can be effectively inhibited, two schemes of protecting dental pulp nerve cells, opening pulp and not opening pulp are achieved, and the problems of multiple complications such as over-changeable blackening and breaking of the existing nerve-killing and root-tip-extraction nerve excision tooth tissue surface are successfully solved; the purpose that the permanent dental pulp nerve cell filling can be completed by one-time minimally invasive rust removal of a patient in about 15 minutes is achieved, the dental pulp nerve cells are protected, dental pulp nerves are not killed, apical nerve cells are completely filled at one time, and time and cost are saved.
Owner:QINGHAI AMINAI BIOTECHNOLOGY CO LTD

Composition for air-polishing the surface of hard dental tissues

PCT designated stageWO2026062340A1Cosmetic preparationsImpression capsSodium fumarateTooth Tissue
The present invention relates to a composition (1) for air-polishing the surface of hard dental tissues, comprising at least: a first abrasive powder capable of polishing hard dental tissues, the first powder being present in the composition in a weight content of between 90% and 99.5%, and a second powder of at least one anti-caking agent, different from the first powder, comprising at least one sodium stearyl fumarate powder present, in the composition, in a weight content of between 0.5% and 5% and having a particle size D50 of between 5 μm and 200 μm, for example between 10 μm and 80 μm, at least 50% of the constituent particles of the second powder having a smallest dimension greater than 100 nm.
Owner:ACTEON MANUFACTURING

Multifunctional safety mouth mirror

ActiveCN223817538USomatoscopeTooth TissueMechanical engineering
The utility model discloses a multifunctional safety mouth mirror which comprises a mouth mirror head, a mouth mirror piece and a mouth mirror handle, one end of the mouth mirror handle is connected with the mouth mirror head, the mouth mirror piece is installed on the mouth mirror head, the mouth mirror head and the mouth mirror handle are hollow and communicated with each other to form a cavity, and a keel capable of moving in the length direction of the mouth mirror handle is arranged in the cavity. The keel is connected with a plurality of tension ropes in a branch shape in the mouth lens head, supporting rods are arranged on the two sides of the mouth lens head, the tension ropes penetrate through the side wall of the mouth lens head and are connected with the supporting rods, a plurality of springs are further connected between the mouth lens head and the supporting rods, and the tension ropes are sleeved with the springs; and a plurality of net bags are arranged between the mouth lens head and the supporting rod. The opening state of the net bag is achieved through the spring, tooth tissue can be blocked and prevented from being swallowed by a patient by mistake, the supporting rod is made to be close to the oral cavity head by pulling the tensioning rope, the net bag is folded, and when the net bag does not need to be used, the net bag is folded, and operation of oral cavity treatment is facilitated.
Owner:WUHAN UNIV

Method for improving surface bonding strength of zirconia veneer

The invention discloses a method for increasing the bonding strength of a zirconia veneering surface, and relates to the field of materials.The zirconia is subjected to plasma treatment through a handheld plasma generator, and then the treated zirconia surface is evenly coated with a layer of resin adhesive containing an Mdp functional monomer. According to the method disclosed by the invention, the Mdp-containing resin adhesive and the argon handheld plasma are used for carrying out bonding treatment on the zirconium oxide restoration material, so that the contact angle is reduced, the surface hydrophilicity is increased, the bonding performance of zirconium oxide is improved, and the connection between the zirconium oxide veneering restoration and the tooth tissue is more stable, so that the risk of falling off of the restoration is reduced.
Owner:FIRST AFFILIATED HOSPITAL OF DALIAN MEDICAL UNIV

Tooth model establishment method, correction scheme design method, correction appliance manufacturing method and correction appliance

The embodiment of the invention discloses a tooth model establishment method, a correction scheme design method, a correction appliance manufacturing method and a correction appliance. The tooth model building method comprises the following steps: acquiring a multi-layer image of an oral cavity by adopting a CBCT (cone beam computed tomography) technology; identifying a tooth pixel point region corresponding to each type of tooth tissue in each layer of image; stacking the multiple layers of images in sequence and acquiring three-dimensional point cloud data of tooth pixel point areas corresponding to various types of tooth tissues; and establishing a three-dimensional tooth model according to the three-dimensional point cloud data of the tooth pixel point area corresponding to each type of tooth tissue. According to the embodiment of the invention, each layer of the multi-layer image is identified, so that the division result is more accurate than that of directly performing division on the complete CBCT image; and finally, stacking the multiple layers of images in sequence to obtain complete three-dimensional data corresponding to each tooth. And the three-dimensional tooth model is established according to the three-dimensional data corresponding to each tooth, so that the division result is more accurate, and the established three-dimensional model is more accurate.
Owner:SHANGHAI SMARTEE DENTI TECH CO LTD

BMP9 to be used in regenerating dental tissue or periodontal tissue

PCT designated stageWO2025173838A1Dental implantsBone implantPeriodontiumTooth Tissue
The present invention provides a dental composition comprising BMP9 to be used in regenerating dental tissue or periodontal tissue, or a method for regenerating dental tissue or periodontal tissue, comprising administering BMP9 to a subject requiring the regeneration of dental tissue or periodontal tissue. The dental tissue can be dentin, and the periodontal tissue can be cementum, alveolar bone, or periodontal ligament. BMP9 according to the present invention is effective, as exhibited by experimental results, in promoting dentin regeneration and periodontal tissue regeneration for teeth.
Owner:NIBEC +1

Gingiva retraction and protection device combined with rubber barrier

ActiveCN223336233UImpression capsDental aidsGingival grooveGingival space
The utility model discloses a gum retraction and protection device combined with a rubber barrier, which comprises a rubber barrier clamp, a mounting block, a push rod, a first locking mechanism, a gum pushing sheet and the like, before subgingival defect repair, the rubber barrier clamp connected with the mounting block is used for fixing the rubber barrier by a barrier splitting method, and a clamping arm connected with the mounting block is positioned on the cheek side, so that the rubber barrier can be fixed by the rubber barrier clamp; in the state, the gingival pushing piece faces one side of the teeth, the push rod is adjusted to drive the gingival pushing piece to be close to the tooth body, so that the gingival pushing piece is arranged in the gingival sulcus and abuts against the subgingival defect section of the tooth body tissue, and at the moment, the first locking mechanism is used for locking the relative position of the push rod and the mounting block so as to keep the support of the gingival pushing piece to the tooth body; and under the condition that an operator does not need to additionally occupy hands, the gum pushing sheet is continuously and stably supported.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Orthodontic toothbrush

The utility model discloses an orthodontic toothbrush, which relates to the technical field of toothbrushes, and comprises a brush handle for a user to hold; the brush head is detachably mounted on the brush handle, and the upper end of the brush head is bent towards the inner side to form an outer side arc-shaped curved surface and an inner side arc-shaped groove; the bristles comprise an upper bristle bundle, a middle bristle bundle and a lower bristle bundle which are all located in the arc-shaped groove, and the upper bristle bundle, the middle bristle bundle and the lower bristle bundle are in a semi-surrounding shape. According to the utility model, the radian of the outer surface is not only matched with the radian of the corresponding buccal mucosa of the back teeth, but also the bristles have a certain angle, so that the distal surface of the back tooth accessory can be effectively cleaned in place, and the tooth tissue around the accessory can be cleaned at the same time.
Owner:BEIJING ANZHEN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

PS-OCT-based detection method for physiological and functional characteristics of hard tissue of tooth body

The invention provides a method for detecting physiological and functional characteristics of tooth hard tissue based on PS-OCT (Pressure Swing-Optical Coherence Tomography). The method comprises the following steps: acquiring an interference signal of tooth hard tissue by using a PS-OCT system; calculating the complex amplitude of the PS-OCT interference signal, and further calculating to obtain a PS-OCT intensity image and various polarization images; based on the PS-OCT phase delay image, calculating and outputting a density parameter of the tooth hard tissue; on the basis of the PS-OCT optical axis image, calculating and outputting a structural confusion degree parameter of the tooth hard tissue; and based on the PS-OCT polarization uniformity image, calculating and outputting a depolarization parameter of the tooth hard tissue. Compared with the prior art, the system and the method have the advantages that high-resolution and large-view-field imaging can be carried out on in-vivo tooth tissue in a real-time and lossless mode by using the PS-OCT technology, intensity images and various polarization images can be obtained at the same time, and physiological and functional characteristics of tooth hard tissue are represented by various parameters.
Owner:NANKAI UNIV

Dental self-adhesive resin composition as well as preparation method and application thereof

The invention provides a dental self-adhesive resin composition and a preparation method and application thereof, the dental self-adhesive resin composition comprises a matrix component and a catalyst component, the matrix component comprises a polymerizable monomer A without an acidic group, a polymerizable monomer containing an acidic group, a photoinitiator, a reducing agent, a flow regulator and a filler A, the catalyst component comprises a polymerizable monomer B which does not contain an acidic group, an oxidizing agent and a filler B; by adding the flow regulator into the matrix component, the obtained self-adhesive resin composition has low viscosity and good fluidity, further has high wettability on the surface of tooth tissue, and can fully penetrate into hard tissue of teeth to improve combination with dentin and enamel, so that the bonding strength is improved, and the service life of the self-adhesive resin composition is prolonged. Meanwhile, the high flexural strength can be kept, and the adhesive is very suitable for being used as a dental adhesive.
Owner:AIDITE (QINHUANGDAO) TECH CO LTD

Human tooth organoids

The invention relates to method for developing and growing tooth organoids comprising the steps of, dissociating tooth tissue comprising dental epithelial stem cells, seeding the dissociated cells in a scaffold mimicking an extracellular matrix; and growing and passaging the cells in a medium suitable for organoid growth, wherein the medium does not comprise epidermal growth factor (EGF), thereby obtaining and expanding organoids.
Owner:KATHOLIEKE UNIV LEUVEN +1

Preparation and use of amorphous calcium phosphate nano-cluster solution

The invention relates to the technical field of oral care or biomedical materials, and discloses preparation and use of an amorphous calcium phosphate nano-cluster solution, the preparation method comprises the following steps: preparing a first solution and a second solution which are isolated from each other before reaction, respectively containing soluble calcium salt and phosphate, according to the method, gamma-polyglutamic acid or gamma-polyglutamate is taken as a raw material, a double-stabilizer system composed of citric acid or sodium citrate and gamma-polyglutamic acid or gamma-polyglutamate is introduced, the two solutions are sprayed out synchronously through a double-cavity device during use, crystal growth is limited through the synergistic effect of the chelating effect and steric hindrance of the stabilizer, and the amorphous calcium phosphate nano-cluster with the particle size smaller than 20 nm is generated in situ. According to the invention, through physical isolation and instant mixing strategies, the problem that amorphous calcium phosphate is easy to agglomerate and inactivate in an aqueous solution is effectively solved; the obtained nano-cluster has excellent permeability, can go deep into a deep layer of a tooth tissue and is converted into hydroxyapatite in situ, so that enamel remineralization and dentin desensitization are realized.
Owner:刘颖

Composition for remineralizing tooth enamel

The invention relates to dentistry, and more particularly to a novel agent in the form of a gel for the treatment and / or prophylaxis of conditions characterized by loss of minerals and salts front tooth enamel. The claimed agent, provided in gel foam, for the treatment and / or prophylaxis of conditions characterized by loss of minerals and salts from tooth enamel contains the following ingredients: 19 wt % glycerin, 10 wt % xylitol 2.3 wt % hydroxyethyl cellulose, 0.09 wt % guar gum, 1.5 wt % calcium glycerophosphate, 0.12 wt % magnesium chloride, 0.9 wt % non-ionic surfactant, 0.24 wt % preservative, 0.04 wt % flavouring agent, she remainder water. The claimed agent provides effective treatment and prophylaxis of the demineralization / hypomineralization of dental tissue, mild forms of fluorosis, and the adverse consequences thereof.
Owner:OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOST YU WDS

Bifunctional peptides for biomimetic reconstruction of silver diamine fluoride treated dental tissues

Described herein are bifunctional peptides, compositions comprising A the same, and methods useful for treatment of dental caries that have been treated with silver diamine fluoride. Treatment with bifunctional peptides remineralizes the carious region to address undesirable tooth discoloration associated with silver diamine fluoride treatment.
Owner:UNIVERSITY OF KANSAS +1