The invention relates to the technical field of water treatment and particularly relates to an advanced reduction method and device for rapidly removing perfluoro-compounds from water. The method comprises the following steps: adding sodium sulfite into wastewater to be treated; putting the sodium sulfite added wastewater into a magnetic stirrer, starting to carry out stirring, and stably maintaining the stirring for 15 minutes in a dark place; putting the stirred wastewater into an inert quartz reaction vessel, opening a slide damper, carrying out high-strength ultraviolet-light source irradiation on the wastewater to be treated, starting to carry out timing, closing the slide damper until selected reaction time reaches, stopping irradiation, and carrying out sampling; determining the PFOA (Perfluorooctanoic Acid)/PFOS (Perfluorooctane sulfonates) concentration of a sample by using a liquid chromatogram-triple quadrupole mass spectrometer, determining fluorine ion concentration by using a fluoride-ion electrode, and calculating a defluorination ratio. According to the method and the device, efficient degradation and defluorination for PFOA/PFOS can be achieved under mild conditions, a photocatalyst is not required to be added during reaction, the cost is reduced, the reaction is rapid, final products are F<->, SO4<2-> and partial fluorinated olefins or alkanes, no secondary pollution is caused, and the aims of high efficiency and low consumption are truly achieved.