54results about How to "Strengthen cells" patented technology

The present invention is directed to novel adjuvant compositions, which target the cellular and / or humoral arms of immunity. According to an embodiment of the invention, an oil-in-water adjuvant composition is provided that comprises: (a) water; (b) a metabolizable oil comprising at least one branched or unbranched long-chain hydrocarbon moiety; (c) a steroid; and (d) a saponin.

The invention relates to a method for enhancing levels of polyunsaturated fatty acid levels in thraustochytrid fungi, using media supplemented with polyvinyl pyrrolidone (PVP) to increase viscosity and which comprises: (a) providing a thraustochytrid fungus strain NIO-TH 21, corresponding to the species Ulkenia radiata Gaertner, being the culture with Accession No. AB22115 of the National Institute of Bioscience and Human-Technology, Japan; (b) inoculating the above said strain in a culture medium; (c) growing the culture for 2 days at a temperature ranging from 25 to 30° C.; (d) obtaining the cultures for use as innoculum using the above said medium to inoculate a medium with different concentrations of polyvinyl pyrrolidone (PVP); (e) growing the culture separately for 2 to 5 days at a temperature ranging from 25 to 30° C.; and (f) harvesting the cells from the above culture by centrifugation and extracting the enhanced amounts of docosahexaenoic acid (DHA) and eicosapentaenoic acids (EPA).

A delivery vehicle is described that is capable of being specifically bound to and taken into targeted cells, delivering numerous physiological agents, particularly paramagnetic ions for magnetic resonance imaging (MRI) of the cells. The delivery vehicle comprises a polymeric molecule having a net positive charge complexed with another polymeric molecule having a net negative charge. Cell targeting moieties and physiological agents, including contrast agents and therapeutic agents, are attached to one or both of the polymeric molecules. In one embodiment, the polymeric molecule having a net negative charge is a nucleic acid. Thus, the delivery vehicles can be used in clinical protocols in which nucleic acids for gene therapy and agents for MRI contrast are co-transported to specific cells allowing medical imaging monitoring of nucleic acid delivery.

A technique for cable interface-based load balancing between first and second cells is described. Each cell comprises cable and air interfaces defining a parameter set comprising load statuses of the cable and air interfaces. A method aspect being performed in a control entity comprises the steps of determining, in the first cell, the parameter set of the first cell, obtaining the parameter set of the second cell, determining whether the load statues of the cable and air interfaces of the first cell are low, whether the air interface load status of the second cell is low, and whether the cable interface load status of the second cell is high, and reconfiguring, if a result of the determination is affirmative, at least one air interface configuration parameter of the first cell so as to off-load at least a part of mobile-originated traffic from the second cell to the first cell.

The invention discloses a preparation method of a pineapple and orange composite ferment beverage. The preparation method comprises the following steps of step I, separately taking raw materials of fresh pineapples and oranges, performing peeling, performing separate dicing and performing uniform mixing so as to obtain fruit raw materials; step II, taking fungus powder, and adding pure water for diluting so as to obtain fermentation fungus water; step III, adding the fungus water to the fruit raw materials until the level of the fungus water exceeds the surfaces of the fruit raw materials, then performing sealing, loading the fruit raw materials and the fungus water, which are sealed, in an incubator for fermentation, after fermentation, taking out the fermented fruit raw materials and the fermented fungus water, performing filtering so as to obtain a ferment stock solution, and placing the ferment stock solution in a refrigerator for after-ripening so as to obtain ferment liquid; step IV, adding honey, pure water and white granulated sugar to the obtained ferment liquid obtained in step III, performing uniform mixing, then adding vitamin C and beta-carotene, and performing homogenizing so as to obtain the pineapple and orange composite ferment beverage. The prepared composite ferment beverage is delicately fragrant in smell, fine and smooth in mouth feel, and moderate in sour and sweet degrees, and the activity of superoxide dismutase (SOD) contained in the composite ferment beverage achieves 100-150U / g.

The invention discloses a multi-panax healthcare food and a preparation method thereof. A brain-invigorating and intelligence-developing healthcare food is made from two or more varieties of the main raw materials such as panax ginseng, panax quinquefolius, radix pseudostellariae and root of pilose asiabell, effective ingredients generated from separation and extraction of the main raw materials, and effective parts made through emendation of the main raw materials or chemical monomers as the main ingredients; the preparation method of the multi-panax healthcare food disclosed by the invention comprises the steps of separation, extraction, emendation and refinement of the main raw materials, namely panax ginseng, panax quinquefolius, radix pseudostellariae and root of pilose asiabell; and dosage forms of the product include but are not limited to pulvis, granules, tablet, hard gelatin capsule, soft gelatin capsule, drop pill, micro-pill, injection medicine, spray medicine, oral liquid and infusion solution. The product can also be researched and developed into a medicament with brain invigoration, intelligence development and memory improving functions according to the relevant regulations of China.

The invention provides a targeting nano carrier bearing nucleoside anti-tumor drugs and preparation method and application thereof. The targeting nano carrier comprises DNA tetrahedron, Affibody molecule and nucleoside anti-tumor drugs. The preparation method comprises the following steps: a, the nucleoside anti-tumor drugs are modified with phosphoramidite; B, synthesizing four DNA single strandsby DNA solid phase synthesis technology, integrating the nucleoside anti-tumor drugs into the 5 'ends of the four DNA single strands, and modifying NH2 at the 3' ends of one of the DNA single strands; C, linking the affibody molecule to the 3 'end of the NH2-modified DNA single strand through a linker; (d) mix and assembling that four DNA single strand in a molar ratio of 1: 1: 1: 1 to obtain DNAtetrahedron; and (d) assembling the four DNA single strands in a molar ratio of 1: 1: 1 to obtain DNA tetrahedron; Affibody targeting nanoparticles. The targeting nano carrier of the invention can precisely control the combined quantity of drugs, has faster tumor targeting ability and higher cell, tissue penetration ability, good pharmaceutical effect, and is suitable for popularization and application.

The present invention provides a Li-ion pouch cell wherein the Li-ion pouch cells comprise a sealed enclosure, electrode stack and thermally conductive elements, wherein the electrode stack and the thermally conductive elements are in the sealed enclosure, the thermally conductive elements include extensions which extend beyond the electrode stack, the sealed enclosure has thermal conductivity, the thermally conductive elements provide a thermally conductive pathway connecting the electrode stack and the sealed enclosure by way of the extension. The present invention also provides a cell module comprising the Li-ion pouch cells. The Li-ion pouch cell and the cell module according to the present application could minimize differences in cell temperature, monitor internal cell temperature, cool the cell rapidly, increase cell and module safety, allowing for minimal impact on cell energy density, performance or life and difficulty of manufacturing.

Porous hydrophilic membranes comprising a porous inert support on which an ionomer is deposited, said membranes being characterized in that they have an ionic conductivity and a water permeability higher than 1 l / (h.m2.Atm).

The invention relates to the technical field of biomaterials, particularly to a bio-based nylon composite PLA material and a preparation method thereof, wherein the raw materials comprise, by weight,10-20 parts of a filler, 40-60 parts of polylactic acid, 1-5 parts of an antioxidant1010, 0.5-2 parts of a plasticizer, 4-8 parts of a compatibilizer, 4-8 parts of a coupling agent, 40-60 parts of a bio-based nylon, 1-5 parts of a polyolefin elastomer, 1-3 parts of modified glass fiber, and 0.01-1 part of glycidyl methacrylate. According to the present invention, the mechanical strength and the size stability of the PLA material are improved by filling the modified glass fiber with the bio-based nylon and the polylactic acid while the bio-based nylon and polylactic acid compounding process isfilled and grafted by using the filler and the high-toughness grafting agent glycidyl methacrylate, such that the bio-based nylon composite PLA material meets the performance requirements of engineering plastics and has good degradability.

The invention relates to a Chinese medicinal composition for treating depression and anxiety, wherein the constituents include (by weight portions) astragalus root 10-20 parts, American ginseng 5-15 parts, white atractylodes rhizome 5-15 parts, gastrodia elata 5-15 parts, wolfberry fruit 5-15 parts, prepared rehmannia root 5-15 parts, white peony root 5-15 parts, donkey-hide gelatin 5-15 parts, root of red rooted saliva 5-15 parts, Chinese angelica root 5-15 parts, rhizome of Sichuan lovage 5-15 parts, epimedium 5-15 parts, wild or spiny jujuba seed 10-20 parts, polygala root 5-15 parts, poria cocos wolf 5-15 parts and hairy deer horn 2-10 parts.

The invention relates to a traditional Chinese medicine for treating myasthenia gravis and amyotrophy. The problem of using medicine for treating myasthenia gravis and amyotrophy is efficiently solved. According to the technical scheme, a method comprises the following steps: respectively crushing the following materials into powder: 13-17g Chinese angelica, 13-17g rhizoma homalomenae, 13-17g pawpaw, 13-17g spatholobus stems, 13-17g sargentgloryvine stems, 9-12g cortex eucommiae and 9-12g cassia twigs; screening by using a 300 mesh sieve, uniformly mixing the powder into fine medicine powder, and standing by; mixing 13-17g rehmannia glutinosa, 13-17g fructus corni, 13-17g medlar, 13-17g fructus psoraleae, 13-17 mistletoe and 13-17g achyranthes bidentata, adding water and decocting, and concentrating decocted liquid into extractum; mixing the fine medicine powder with the extractum and preparing into a medicine lump; pelletizing and drying; and coating and packaging. The traditional Chinese medicine is used for efficiently treating the myasthenia gravis and amyotrophy and has the functions of strengthening the muscle, forming the muscle, strengthening tendon and bones, nourishing liver and kidney, promoting blood circulation and removing blood stasis, promoting the immunity of organism, nourishing and repairing nerve and muscle cells, increasing the endurance of the cells and enhancing the muscle vigor. The traditional Chinese medicine is excellent in curative effect, is free from toxic side effects, is conveniently and simply taken and is safe and reliable.

The invention discloses ferment jelly drops. The formula contains 8-14 parts of white granulated sugar, 6-12 parts of glucose syrup, 15-25 parts of water, 3-8 parts of pectin, 11-16 parts of ferment and 1-2 parts of natural essence. The invention further provides a preparation method of the ferment jelly drops. The ferment is used as a material of the jelly drops; and the jelly drops have good jelly drop taste effect and also has good chewing effect.

The invention discloses polypeptide anti-wrinkle firming eye cream and a preparation process thereof. The polypeptide anti-wrinkle firming eye cream comprises the following components in percentage bymass: a material A, a material B, a material C, a material D and 0-1% of polypeptide, wherein the material A comprises, in percentage by mass, 40-50% of deionized water, 4-8% of butanediol, 3-6% of glycerol, 0-0.1% of p-hydroxyacetophenone, 0-0.5% of sodium polyacrylate and 0-0.5% of EDTA disodium salt; the material B comprises, in percentage by mass, 5-10% of squalane, 2-4% of docosyl alcohol, 2-4% of polyglycerol-3 methyl glucose distearate, 2-4% of polydimethylsiloxane, 1-3% of diisostearyl malate, 1-3% of meadowfoam seed oil, 0-1% of stearic acid, 0-1% of an emulsifier and 0.5%-3.5% of emollient; and the material C comprises, in percentage by mass, 1-3% of phytosterol / behenyl alcohol / octyldecyl lauroyl glutamate, 1-3% of 1,2-pentanediol and 0-1% of a thickening agent. The polypeptideraw material is added into the eye cream, so wrinkles can be effectively removed and resisted, and better wrinkle removing and wrinkle resisting effects are obtained after continuous use of the eye cream.

The invention belongs to the medical field of biotechnology medicine and discloses a preparation method and clinical application of larix gmelini arabinogalactan composition. The larix gmelini arabinogalactan composition comprises, by weight, 3-6 parts of larix gmelini arabinogalactan, 0.5-3 parts of inulin and 0.4-3 parts of coconut nut powder. The preparation method includes the steps of S1, extracting the arabinogalactan from larix gmelini; S2, preparing defatted coconut powder; sterilizing the finished product. The preparation method the advantage of low cost, static ultra-high pressure room temperature treatment is simple and easy to implement, a great deal of energy can be saved, and objects are extracted completely and thoroughly; the larix gmelini arabinogalactan composition is provided to be effective in the treatment of diarrhea irritable bowel syndrome by volunteer clinical trials, and drug therapy with certain side effects is replaced by dietary therapy.

The present invention is directed to recombinant fibronectin peptide mimetics and wound healing compositions containing the same. Other aspects of the present invention include wound healing dressings that comprise the wound healing composition of the present invention and a wound dressing material and methods of treating wounds using these compositions.

The invention relates to a medicine composite for curing combined external head injuries in clinical nursing. The medicine composite is prepared from following raw materials in parts by weight: 27 parts of prepared rehmannia root, 25 parts of Chinese angelica, 25 parts of radix paeoniae rubrathe, 22 parts of curcuma rhizome, 22 parts of dandelion, 20 parts of radish seed, 20 parts of patrinia herb, 18 parts of plantain seed, 18 parts of Japanese eupatorium, 17 parts of eucommia, 15 parts of campsis grandiflora, 15 parts of cassia twig, 15 parts of perilla leaf, 15 parts of Chinese yam, 13 parts of banksia rose, 12 parts of mulberry, 12 parts of poria cocos, 12 parts of licorice, 10 parts of saposhnicovia divaricata, 10 parts of trichosanthes root, 10 parts of cyperus rotundus, 10 parts of albizia bark, 8 parts of ligusticum wallichii, 8 parts of edible fungus, 7 parts of barbat skullcap, 5 parts of almond, 5 parts of phellodendron, 3 parts of prunella vulgaris and 3 parts of wolfberry. The materials mentioned above are used together to bring out the best in each other, the medicine composite has a rapid curative effect on the combined external head injuries and the application prospect is vast.

A traditional Chinese medicine formula for treating femoral head lesions is characterized by comprising the following components: 20 grams of peach seed, 20 grams of Amomum villosum, 15 grams of Rhizoma Drynariae, 12 grams of antlers, 12 grams of dog bone, 12 grams of rhizoma anemarrhenae, 10 grams of Chinese angelica, 10 grams of Caulis Spatholobi, 10 grams of pseudo-ginseng, 8 grams of Radix Achyranthis Bidentatae, 8 grams of Ligusticum wallichii, and one sea cucumber. A method is as below: crushing the sea cucumber into a powder, decocting the powder with the above-mentioned materials in water, taking the juice 30 min later for drinking once a day. The formula solves the problems in the traditional Chinese medicine prescription for treating femoral head diseases, such as slow effect, unobvious effect, failure to repair caput femoris cells, no effect on hyperosteogeny and femoral head necrosis, and even aggravation of the condition, and is suitable for the treatment of the femoral head lesions.

The present invention discloses a ginsenoside-containing vaccine diluent, which comprises, by weight, 0.004-0.012% of ginseng stem leaf saponin or ginsenoside, 0.001-0.01% of thimerosal, and the balance of physiological saline. According to the present invention, after the vaccine diluted by using the vaccine diluent containing the ginseng stem leaf saponin (GSLS) or ginsenoside (GS) and the thimerosal is used to immunize animals, the immunizing effect can be substantially improved; and one of the main components of the diluent is the thimerosal having the preservative effect, such that the preservative for preventing the product from mildew is not required to be added.

The invention relates to a preparation method of a matrine transdermal agent. The method comprises the following steps: (1) successively dissolving matrine in anhydrous ethanol and distilled water; (2) heating to prepare a chitosan glacial acetic acid solution; (3) mixing a traditional Chinese herbal extract with the chitosan glacial acetic acid solution; (4) adding the mixture into an emulsification system for emulsification; (5) conducting a cross-linking reaction on the emulsion products; and (6) treating the crosslinking products by washing, precipitation, centrifugation and drying to obtain a transdermal medical membrane loaded with traditional Chinese herbal extract. The preparation method is simple, and suitable for large-scale industrial production.

The invention discloses a biodegradable plastic sole material and a preparation method thereof. The biodegradable plastic sole material is prepared from the following raw material components in partsby weight: 80-100 parts of EVA aggregates, 20-30 parts of high-density polyethylene, 25-35 parts of ethylene-acrylate copolymers, 10-30 parts of ethylene-octene copolymers, 30-40 parts of modified poplar powder, 5-8 parts of activator mixture, 2-4 parts of talcum powder, 2-4 parts of foaming agent and 3-5 parts of crosslinking agent. A sole prepared according to a formula has good dampproof and waterproof effects and also has good toughness, wear resistance and slip resistance, and the plastic sole is degradable so that environment pollution can be avoided.

The special diluent for swine mycoplasma pneumonia vaccine of the present invention mainly contains recombinant P97R1 protein immunostimulatory complex (ISCOM-P97R1), and may also contain other aqueous adjuvant components, including levamisole, or / and astragalus polysaccharide, or / and carboxy bohm. Each ml solution of the diluent contains 0.1-1 mg of QuilA, 0.02-0.2 mg of cholesterol, 0.02-0.2 mg of phosphatidylcholine, 0.4-4 mg of P97R1 antigen, and may further contain 2-20 mg of levamisole , or / and astragalus polysaccharide 20-100 mg, or / and carbomer 3-10 mg, and the rest is phosphate buffer. This diluent is specially used for dissolving or diluting Mycoplasma pneumoniae vaccine, including live vaccine and inactivated vaccine. It has the dual effects of supplementing the protective spectrum of vaccine antigens and enhancing the immune stimulating ability of vaccine cells and humoral, which can significantly improve the protective efficacy of vaccines against viruses. At the same time, due to the use of the water solvent system, it also has the advantages of simple operation, good needle penetration, and no obvious toxic and side effects.

The present invention provides a protein having a potent cell-death inducing activity that is, a fused protein is in which a modified Bax protein fused with GFP at the N-terminus and is further fused with a homing signal peptide having a homing activity specific for endothelial cells in tumor angiogenesis; a gene coding the fused protein; and a cancer cell growth inhibitor containing the fused protein. Namely, a fused gene containing a cell death-inducing gene acting specially on cancer tissue, which is a fused gene having a gene encoding a homing signal peptide sequence specific for endothelial cells undergoing angiogenesis, a gene encoding a green fluorescent protein (GFP) and a gene encoding ΔNBax protein, which is human Bax with a deletion of the N-terminal sequence containing the BH3 domain in this order, and a fusion protein encoded by the fused gene.

The invention discloses a polyurethane thermal panel and a production process thereof. The panel comprises composite polyether and isocyanate. The composite polyether comprises compound polyhydric alcohols, an amine catalyst, a foam stabilizer, a foaming agent, a flame retardant and modified graphene. The ratio of raw materials is strictly controlled in the production process, the mixing ratio ofthe raw materials is accurately measured, and the efficiency and stable-quality continuous production of the polyurethane thermal panel is realized through mixing, casting and foaming of a quick spraying gun of a foaming machine.

The invention relates to a medicine composite for curing combined external head injuries in clinical nursing. The medicine composite is prepared from following raw materials in parts by weight: 27 parts of prepared rehmannia root, 25 parts of Chinese angelica, 25 parts of radix paeoniae rubrathe, 22 parts of curcuma rhizome, 22 parts of dandelion, 20 parts of radish seed, 20 parts of patrinia herb, 18 parts of plantain seed, 18 parts of Japanese eupatorium, 17 parts of eucommia, 15 parts of campsis grandiflora, 15 parts of cassia twig, 15 parts of perilla leaf, 15 parts of Chinese yam, 13 parts of banksia rose, 12 parts of mulberry, 12 parts of poria cocos, 12 parts of licorice, 10 parts of saposhnicovia divaricata, 10 parts of trichosanthes root, 10 parts of cyperus rotundus, 10 parts of albizia bark, 8 parts of ligusticum wallichii, 8 parts of edible fungus, 7 parts of barbat skullcap, 5 parts of almond, 5 parts of phellodendron, 3 parts of prunella vulgaris and 3 parts of wolfberry. The materials mentioned above are used together to bring out the best in each other, the medicine composite has a rapid curative effect on the combined external head injuries and the application prospect is vast.

The iCP-RF recombinant protein of present invention could mediate generation of the induced pluripotent stem cells (iPSCs) from terminally differentiated somatic cells.

The invention relates to the technical field of skin care, in particular to a mask application method. The mask application method comprises the following specific steps: taking out a mask from a bag, and placing the mask in a mask grinding tool; pouring essence on mask cloth and uniformly smearing the essence on the mask cloth with a small brush so as to fully infiltrate the whole mask; applying the infiltrated facial mask onto a facial contour; connecting clout nails of the mask with a handheld controller through clout nail connecting lines; selecting and pressing a gear button on a conductive rod, and adjusting the force of micro-current on the face through the gear button; after standing for 20-25 minutes, taking down corresponding accessories, and discarding the mask; and then gently massaged the facial skin so as to allow the essence to be fully absorbed. The invention provides the mask application method which is obvious in effect and capable of well absorbing essence and preventing facial moisture loss.

The invention discloses a cell breaking process and system of a solid-liquid mixed phase by direct quick flash evaporation. The method comprises the following steps of: feeding biomass waste to a pulpifying reactor for heating and preheating; then, pumping into a hydrothermal reactor, and heating to reaction temperature; after hydrothermal reaction, performing direct depressurization and flash evaporation on a high-temperature high-pressure solid-liquid phase mixed material, wherein the material expands and is gasified severely, and the pressure is reduced quickly, and then, entering into a flash reactor; separating the depressurized material in the flash reactor from steam and entering into a cooling system for cooling; and directly dehydrating the cooled material or entering into an anaerobic digestion system for subsequent treatment. According to the invention, the mode of direct flash evaporation of the solid-liquid mixed phase rather than depressurized flash evaporation to the gas phase of the high temperature and high pressure reactor is adopted. The flash evaporation process of the process directly acts on the solid phase, so that the cell structure is more efficiently damaged, and intracellular matters are accelerated to be dissolved out.