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Medicine for treating hyperlipemia

A technology for hyperlipidemia and drugs, which is applied in the field of traditional Chinese medicine preparations for the treatment of hyperlipidemia, can solve problems such as liver and kidney function and granulocyte count adverse changes, endocrine disorders, drug tolerance, etc., and is suitable for large-scale industrial The effect of production, less toxic and side effects, and easy availability of raw materials

Active Publication Date: 2005-06-22
深圳前海吉奥健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned lipid-lowering drugs can achieve good results in a short period of time, there are still many problems to be explored and solved: ①After the lipid-lowering target is reached, once the drug is stopped, the curative effect is difficult to stabilize and consolidate, and even a vicious rebound in blood lipid levels occurs ; ②Lipid-lowering drugs often cause gastrointestinal discomfort in clinical application, such as abdominal pain, constipation, flatulence, nausea, vomiting, diarrhea, indigestion, loss of appetite and other adverse reactions, in addition, liver and kidney function and granulocyte count are prone to occur ③Sharp lipid-lowering can easily induce senile mental and emotional changes or sudden cardiovascular and cerebrovascular events; ④Premenopausal women are prone to endocrine disorders after lipid-lowering treatment, while postmenopausal women are prone to endocrine disorders due to lipid-lowering treatment. Symptoms of secretion disorders further aggravated
There are still some deficiencies in the above-mentioned drugs. There is a lack of unified standards for clinical research on the treatment of hyperlipidemia with traditional Chinese medicine, such as inconsistent case selection, curative effect determination, and control group settings. Or side effects, or long-term use to produce drug tolerance and other disadvantages

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0148] Example 1. Take 3 kg of Ligustrum lucidum, 1.5 kg of Atractylodes macrocephala, 1.5 kg of Eucommia ulmoides, 2 kg of salvia miltiorrhiza, 0.5 kg of bergamot, and 1.5 kg of thistle, add 75 L of water, boil for 2 hours, filter, add 60 L of water to the filter residue, and boil for 1.5 hours , filtered, and the combined filtrate was concentrated, dried, sieved, and packed into capsules, 300 mg per capsule.

Embodiment 2

[0149] Example 2: Take 3 kg of medicinal materials Ligustrum lucidum, 1.5 kg of Atractylodes macrocephala, 1.5 kg of Eucommia ulmoides, 2 kg of salvia miltiorrhiza, 0.5 kg of bergamot, 1.5 kg of thistle, add 60L of 70% ethanol, boil for 2 hours, filter, and add 70% ethanol to the filter residue 50L, boil for 1.5 hours, filter, combine the filtrate to recover ethanol and concentrate to form a thick paste, add sugar powder or dextrin, stir evenly, granulate, dry, sieve, and pack into granules (also known as granules) of 10g per bag.

Embodiment 3

[0150] Example 3. Take 1.5 kg of medicinal materials Ligustrum lucidum, 1.5 kg of Atractylodes macrocephala, 1.5 kg of Eucommia ulmoides, 2 kg of salvia miltiorrhiza, 1.5 kg of bergamot, 2 kg of thistle, add 75 L of water, boil for 2 hours, filter, add 60 L of water to the filter residue, and boil for 1.5 hours. Filter, combine and concentrate the filtrate to a thick paste with a relative density of 1.25, add water and flavorings, etc. to dilute to contain 2g of crude drug per ml, and pack into oral liquids of each 10ml.

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PUM

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Abstract

Disclosed is a Chinese medicinal preparatoinfor treating hyperlipemia, which is prepared from Chinese medicinal herbs including (by weight ratio), ligustrum japonicum 15-30%, root of japanese thistle 10-20%, white atractylodes rhizome 5-20%, radix salvia miltiorrhiza 5-20%, eucommia bark 5-15%, and Buddha's hand 5-15%.

Description

technical field [0001] The invention belongs to medical preparations derived from plant materials, in particular to a traditional Chinese medicine preparation for treating hyperlipidemia. Background technique [0002] Hyperlipidemia is a common and frequently-occurring disease, and the detection rate of men and women is about 11.6% and 18.2% respectively. Hyperlipidemia is closely related to hypertension, hyperglycemia and aging, and is most closely related to the incidence of coronary heart disease. According to a survey by the World Health Organization, 75% of people in the world are in a sub-healthy state, such as hyperlipidemia, high blood pressure, high blood sugar, high body weight and low immune function. Therefore, effective control of hyperlipidemia It is of great practical significance to treat hyperlipidemia and even cure hyperlipidemia. [0003] At present, there are synthetic drugs for effectively controlling hyperlipidemia and treat...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61P3/06
Inventor 郭姣
Owner 深圳前海吉奥健康科技有限公司
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