199 results about "Ethanol extracts" patented technology

The invention discloses a propolis ethanol extract loaded ZIF-8 cellulose starch-based sustained-release film and a preparation method thereof, and belongs to the technical field of food preservative films. The propolis ethanol extract loaded ZIF-8 cellulose starch-based sustained release membrane is prepared from the following raw materials in parts by weight: 30 to 70 parts of starch, 30 to 70 parts of cellulose nanofiber, 7.5 to 17.5 parts of glycerol and 4 to 8 parts of filler. The starch wastewater is used as a starch raw material source, and the cellulose nanofibers loaded with ZIF-8 by the propolis ethanol extract are added, so that the prepared slow-release film is high in strength and good in toughness, can be naturally degraded after being used, reduces environmental pollution, ensures the safety of the product, has antibacterial and antioxidant effects, provides benefits for fresh keeping of fruits, and has a wide application prospect. Meanwhile, a new thought is provided for resource utilization of the starch wastewater.

The invention relates to the technical field of soil improvement, in particular to a pineapple planting soil improvement method and a special modifier thereof. According to the pineapple planting soil improvement method, the special improver for the pineapple planting soil is applied to the soil before planting, the application amount is 15-25 kg / mu, and shallow turning is conducted after application; the special modifier for the pineapple planting soil is prepared from the following raw materials in percentage by mass: 35 to 65 percent of activated carbon or loaded activated carbon, 30 to 60 percent of cake fertilizer containing nematode inhibiting substances, 0.5 to 5 percent of loaded pomegranate peel ethanol extract and the balance of adhesive. The cake fertilizer (such as cottonseed meal and tea seed meal) containing the nematode inhibiting substance is an agricultural by-product, the raw materials are easy to obtain, and the cost is low; the activated carbon can be prepared from agricultural and forestry wastes (such as coconut shell charcoal), and accords with circular economy. Meanwhile, the environment-friendly and environment-friendly pesticide is eco-friendly, biodegradable, free of chemical residues and capable of killing insects and inhibiting bacteria at the same time.

The invention discloses a saussurea involucrata culture as well as a preparation method and application thereof, and belongs to the technical field of bioengineering and medicines. The invention relates to a saussurea involucrata culture, in particular to a selenium-rich and chromium-rich saussurea involucrata cell culture with DPP-IV inhibitory activity. The content of selenium in the saussurea involucrata culture reaches 200 mg / Kg dry weight or above, and the content of chromium Cr < 3 + > reaches 20 mg / Kg dry weight or above; in addition, chromium Cr < 6 + > is not detected, and the 70% ethanol extract of the saussurea involucrata cell culture is applied to an in-vitro DPP-IV inhibition test, and the inhibition rate of the 70% ethanol extract of the saussurea involucrata cell culture reaches 99.08%. The selenium-rich and chromium-rich saussurea involucrata culture with the high DPP-IV inhibition rate can be widely applied to preparation of medicines, health foods or functional foods for preventing and / or treating type 2 diabetes, obesity and related metabolic diseases.

The invention discloses a preparation method of an astragalus extract with a uric acid reducing effect, and belongs to the technical field of biological medicines. The method comprises the following steps: concentrating an ethanol extract of radix astragali, extracting by using n-butyl alcohol, ethyl acetate and petroleum ether respectively, and concentrating an extract to obtain n-butyl alcohol, ethyl acetate and petroleum ether extraction parts and residual parts respectively, so as to obtain an n-butyl alcohol extract, namely the radix astragali extract for reducing uric acid. Efficacy experiments show that the normal butanol extraction part of the ethanol extract of the astragalus membranaceus can obviously reduce the serum uric acid level (SUA) of a mouse with hyperuricemia, inhibit the activity of xanthine oxidase (XOD) and effectively improve kidney injury caused by the hyperuricemia. The uric acid reducing effect of the radix astragali n-butyl alcohol extract is close to that of a clinical drug allopurinol, and the radix astragali n-butyl alcohol extract has wide development and application prospects in the aspect of relieving hyperuricemia.

The invention provides a method for rapidly detecting the ABTS < + > free radical scavenging rate of a traditional Chinese medicine extract based on Fourier infrared spectroscopy, which comprises the following steps: (1) collecting the Fourier infrared spectroscopy of a dandelion ethanol extract, and measuring the true value of the ABTS < + > free radical scavenging rate corresponding to the Fourier infrared spectroscopy by using spectrophotometry; (2) preprocessing the collected Fourier infrared spectrum to obtain a preprocessed spectrum; (3) carrying out characteristic wavelength variable extraction on the preprocessed spectrum by adopting a VIP algorithm, and combining spectrum segments corresponding to extracted characteristic wavelengths into a characteristic spectrum; (4) performing PCA analysis and step length segmentation processing on the characteristic spectrum to obtain an angle characteristic vector alpha y, and forming an angle characteristic matrix alpha by the angle characteristic vectors of all the traditional Chinese medicine extracts; and (5) constructing a regression model by using the angle feature vector matrix alpha. Compared with a traditional spectrophotometric detection method, the method has the advantage that the accuracy and the stability of a detection result can be better improved.

This invention discloses a method for determining the components of an ethanol extract of *Clerodendrum trichotomum* leaves. A liquid chromatography-mass spectrometry (LC-MS) method was established to detect the content of the ethanol extract. Raw data acquired by mass spectrometry was retrieved using software and compared with a mass spectrometry database to identify the chemical components of the ethanol extract. Ultimately, 44 chemical components were detected in the ethanol extract, providing a basis for the quality and efficacy evaluation of *Clerodendrum trichotomum* medicinal materials.

A method for improving skin elasticity includes use of a composition containing an ethanol-extracted product of Aronia melanocarpa fruit and Bifidobacterium longum CB108 which is deposited at the Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH under an accession number DSM 33895 in accordance with the Budapest Treaty.

The present invention discloses a sesquiterpene glycoside compound and its preparation method and application. A new sesquiterpene glycoside ligulariatinside A is isolated and identified from the n-butanol extraction part of 95% ethanol extract from the root of Ligularia glossata by multiple chromatographic methods such as macroporous resin column chromatography, positive and reverse phase silica gel column chromatography and high performance liquid chromatography, as well as spectral methods. The molecular formula of the new sesquiterpene glycoside ligulariatinside A is determined to be C 21 H 34 O7, the structure is (3 S ,4 R ,5 R ,7 R )‑11‑hydroxy‑11,12‑dihydronootkatone‑11‑ O ‑ β ‑D‑glucopyranoside enriches the chemical diversity of Ligularia officinalis. Bacterial inhibition experiments revealed that the new sesquiterpenoid glycoside exhibits inhibitory activity against Vibrio anguillarum, with a minimum inhibitory concentration (MIC) of 50 μg / mL, laying the foundation for the development of new antibacterial drugs.

The application discloses a preparation method of ethanol extract of Drynaria Rhizome and application thereof. The method comprises the following steps: crushing and sieving Drynaria Rhizome, adding ethanol, reflux extraction, combining filtrates, vacuum concentration and drying, and thus the ethanol extract of Drynaria Rhizome is obtained. The in-vitro alpha-glucosidase enzyme inhibition experiment shows that the ethanol extract of Drynaria Rhizome has a significant inhibitory effect on alpha-glucosidase enzyme, and the IC 50 is about 142.68 μ g / mL. Therefore, the ethanol extract of Drynaria Rhizome can be used for preparing a hypoglycemic drug, health care product or functional food, and has a wide application prospect.

Natural turmeric and hibiscus inks were developed for use on fabrics and writing surfaces. Ethanolic extracts of turmeric and hibiscus were obtained and formulated with environmentally friendly mordants such as ferrous sulfate, ascorbic acid, and apple cider vinegar, and thickeners such as linseed oil and aloe vera. These treatments were tested on fabric, filter paper, and notebook paper. Color and color loss were evaluated using the Paint program when exposed to sunlight and washing (in the case of fabric), comparing the RGB and Hex pixel values ​​obtained before and after sun exposure and washing. The degree of similarity was assessed using a digital Color Matcher Tool with the Hex and RGB data. Once the best treatment with the aforementioned mordants was determined, the ink formulation was developed using thickeners such as gelatin, alginate, cornstarch, and honey.It has a pleasing color and good consistency for use on fabric and paper. It's possible to create inks for writing and dyeing fabrics with readily available ingredients, thus contributing to environmental protection.

This invention relates to the field of natural product chemistry, specifically to the application of a *Syzygium brevicornum* leaf extract in the preparation of drugs for the prevention and / or treatment of atherosclerosis. The preparation method of the *Syzygium brevicornum* leaf extract of this invention includes the following steps: taking dried *Syzygium brevicornum* leaves, extracting with ethanol solution, filtering, combining the extracts, and concentrating under reduced pressure to obtain a total extract of *Syzygium brevicornum* leaf ethanol extract; extracting the total extract of *Syzygium brevicornum* leaf ethanol extract with ethyl acetate to obtain the *Syzygium brevicornum* leaf extract. Using the RAW264.7 foam cell model, this invention found that the *Syzygium brevicornum* leaf extract prepared by this invention can reduce lipid accumulation in RAW264.7 macrophage-derived foam cells, suggesting that the *Syzygium brevicornum* leaf extract prepared by this invention can be used to prepare drugs for the prevention and / or treatment of atherosclerosis.

The invention relates to a preparation method and application of an effective part of hyssop officinalis L. The method comprises the following steps: taking hyssop officinalis L., cutting into cun sections, carrying out reflux extraction with ethanol, filtering, merging filtrates, carrying out vacuum concentration, and carrying out vacuum drying to obtain a hyssop officinalis L. ethanol extract; and dissolving the extract in ethanol, extracting with ethyl acetate, concentrating the upper layer under reduced pressure, and drying in vacuum to obtain the effective part of hyssop officinalis. The invention further discloses application of the effective part of the hyssop officinalis obtained through testing in preparation of the anti-allergic asthma medicine.

The present application relates to a kind of blended fabric segmented steaming fixation method, comprising the following steps: blended fabric is sequentially carried out desizing, kiering, bleaching and mercerizing treatment, and pretreatment blended fabric is obtained after drying;Using composite reagent on pretreatment blended fabric is carried out padding treatment or vacuum-assisted foam impregnation treatment, and pre-treatment blended fabric is obtained after hot air drying;Prepare dye liquor, and after using dye liquor on pre-treatment blended fabric is carried out dye liquor padding treatment, then carry out segmented steaming fixation treatment, and after sequentially washing, drying, setting, obtain dyed blended fabric.The present application uses the composite reagent containing Ageratina pichurini ethanol extract and simmondsia chinensis seed oil to carry out padding treatment or vacuum-assisted foam impregnation treatment on blended fabric before dyeing, then carries out segmented steaming fixation treatment, can significantly improve the tensile strength and wash fastness of blended fabric, while giving blended fabric good gloss, and can make blended fabric keep better perspiration fastness.

The invention discloses a mosquito prevention and control composition based on jonquil extract and application of the mosquito prevention and control composition. The invention provides an application of an ethanol extract of jonquil leaves in killing mosquitoes or preparing products for killing mosquitoes. The invention firstly proves that the kalanchoe blossfeldiana ethanol extract has a killing effect on three mosquito species, and the killing effect is obviously superior to that of kalanchoe laciniata which is the same family plant. The invention further provides a mosquito prevention and control composition containing the ethanol extract of the jonquil leaves and a mosquito prevention and control compound composition containing the ethanol extract of the jonquil leaves and dinotefuran. The insecticide poison bait prepared by compounding the jonquil extract and the chemical insecticide provides a new thought for constructing an efficient, low-consumption and environment-friendly mosquito comprehensive treatment system, and is suitable for comprehensive prevention and control of mosquito-borne diseases.

The application discloses an immune function enhancing composition which is mixed by sambucus williamsii alcohols extract and lactobacillus rhamnosus agent. The application can effectively immunize the spleen, improve the spleen index and thymus index, has the function of immune regulation, and can also improve the IgM and IgG content in serum.

The invention relates to the technical field of modernization of traditional Chinese medicines, in particular to a nano-vesicle, a preparation method and application of the nano-vesicle in preparation of an endometrial injury repairing medicine. The preparation method comprises the following steps: taking a periplaneta americana ethanol extracting solution, and adding a buffer solution to prepare diluted homogenate; performing differential centrifugal treatment on the homogenate; filtering the supernatant obtained by the differential centrifugation treatment, and then centrifuging for 60-120 minutes by 100000g of the supernatant to obtain a precipitate; and re-suspending the precipitate to obtain the periplaneta americana ethanol extract source nano-vesicles. The periplaneta americana ethanol extract is used as a starting material to enrich the nano-vesicles for the first time, the combined process of differential centrifugation, membrane filtration and ultracentrifugation is adopted, the obtained nano-vesicles can be applied to the field of endometrial injury repair, especially treatment of gynecological diseases such as intrauterine adhesion and infertility with thin intima, and the blank in the technical field is filled.

The present application provides a kind of streptomyces, named Streptomyces sp., is registered and preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No:65917.The present application also provides fermentation broth of the streptomyces and ethanol extract and crude extract of fermentation broth thereof.The new species of streptomyces and its crude extract and the like of the present application have broad-spectrum antibacterial activity, have good antagonism to many pathogenic bacteria such as banana long-shaped spot fungus and banana anthracnose fungus, and can make banana anthracnose fungus hyphae wrinkle, deform, break, inhibit banana anthracnose fungus spore germination, make banana anthracnose fungus spore germination wrinkle, break, inhibit banana anthracnose fungus growth, and can also improve peroxidase, polyperoxidase, CAT activity and the like in banana peel, is a potential biological agent for preventing and treating anthracnose disease, stem rot disease and the like, has broad development space, and has good development and application prospect.

The invention discloses a traditional Chinese medicine monomer composition derived from chrysanthemum plants and used for treating diabetic retinopathy as well as a preparation method and application of the traditional Chinese medicine monomer composition. The traditional Chinese medicine monomer composition prepared from the chrysanthemum plant as the raw material is high in safety, small in side effect and definite in component and is prepared according to a specific ratio, and pharmacodynamic experiments prove that compared with an ethanol extract, the traditional Chinese medicine monomer composition is more remarkable in curative effect on diabetic retinopathy, and the curative effect of the traditional Chinese medicine monomer composition on diabetic retinopathy is better than that of a traditional Chinese medicine composition on diabetic retinopathy. The composition can improve the pathological state of diabetic retinopathy from multiple targets and multiple ways, specifically can inhibit body mass increase caused by high glucose, reduce blood glucose level, improve retinal tissue structure damage, recover retinal tissue thickness, inhibit retinal cell apoptosis and inflammatory response, reduce the expression level of HIF-1alpha and VEGF protein in retinal tissue, and can be used for treating diabetic retinopathy. Scientific basis and technical support are provided for research and development of novel drugs for treating the diabetic retinopathy, and important clinical significance and market application prospects are achieved.

The invention provides a high-stability black wolfberry fruit lipid-regulating oral liquid and a preparation method thereof, and relates to the technical field of medicines. The semen cassiae and fructus lycii lipid-regulating oral liquid is prepared from semen cassiae ethanol extract, mixed water extract, aromatic water, a flavoring agent, a bacteriostatic agent, a pH regulator and a solubilizer. By optimizing the preparation process, the provided black wolfberry fruit lipid-regulating oral liquid is under the action of the specific flavoring agent, the bacteriostatic agent, the pH regulator and the solubilizer, the solubilizer is polyethylene glycol 400 or a mixture of polyethylene glycol 400 and polyethylene glycol 600, the content degradation speed of stilbene glucoside is obviously slowed down, the validity period of the product is prolonged from 18 months to 24 months, and the stability of the product is improved.

The invention relates to a dictyophora rubrovolvata fresh-keeping method and fresh-keeping powder used by the same. The fresh-keeping powder is prepared from the following raw materials in percentage by mass: 0.1-1% of ethanol extract of bacilli of dictyophora rubrovolvata, 5-30% of bacilli polysaccharide, 10-50% of chitosan and 20-85% of corn starch (2-8% of calcium chloride is added). The powder provided by the invention contains dictyophora rubrovolvata mycosterol, terpene and polysaccharide substances, contains low-acetyl-degree chitosan with strong antibacterial ability and certain water solubility, and absorbs moisture of the dictyophora rubrovolvata body after being contacted with the newly picked dictyophora rubrovolvata, acidic mycosterol with negative charges and alkaline low-acetyl-degree chitosan with positive charges are subjected to electrostatic adsorption reaction, so that the moisture of the dictyophora rubrovolvata can be absorbed, and the moisture of the dictyophora rubrovolvata can be absorbed; the components are mutually attracted to form a local film, so that the moisture of the mushroom body can be locked, the mass loss and hardness reduction can be relieved, the freshness can be kept through oxidation resistance and bacteria resistance, the peroxidation degree of film lipid can be relieved, the cell integrity can be maintained, and the retention rate of nutrient substances such as reducing sugar and soluble protein can be effectively increased.

The invention relates to the field of biology, in particular to a composition of a rhodiola rosea alcohol extract and a nannochloropsis oculata extracting solution and application of the composition. The weight volume ratio of the rhodiola rosea alcohol extract to the nannochloropsis oculata extracting solution in the composition is (0.005 to 0.1) g: (0.02 to 0.5) mL. After the rhodiola rosea alcohol extract and the nannochloropsis oculata extracting solution are combined, the ROS content after hydrogen peroxide induction can be reduced.

This invention provides a compound Phellodendron amurense freeze-dried powder and its preparation process, relating to the field of deep processing technology of compound Phellodendron amurense extract. The preparation process includes the following steps: 80±10 parts by weight of Forsythia suspensa, 40±5 parts by weight of Phellodendron amurense, 40±5 parts by weight of Lonicera japonica, 40±5 parts by weight of Taraxacum mongolicum, and 2.4±0.3 parts by weight of Scolopendra subspinipes. S1: Take a certain weight of the above five ingredients, add water and decoct, concentrate to a clear extract with a relative density of 1.10-1.15, add ethanol to make the alcohol content reach 70%, let stand, concentrate until there is no alcohol odor, and obtain compound Phellodendron amurense ethanol extract; S2: Take the compound Phellodendron amurense ethanol extract, add water to a certain volume, refrigerate, filter, and obtain compound Phellodendron amurense freeze-dried stock solution; S3: Take the compound Phellodendron amurense freeze-dried stock solution, fill, and freeze-dry to obtain compound Phellodendron amurense freeze-dried powder. The compound Phellodendron amurense freeze-dried powder prepared by this invention solves the problems of existing coatings being non-sterile, unstable, and inconvenient to transport.

The present invention provides a method of isolating arjunetin from the bark of Terminalia arjuna. The invention provides a simplified, cost-effective method and scalable method for isolation of arjunetin from the Terminalia bark. The present invention encompasses an ethanolic extract of arjunetin that comprises arjunetin with 95% purity. The ethanolic extract of arjunetin is obtained from solvent extraction without using column chromatography. Arjunetin has various therapeutic applications, anti-diabetic, anti-inflammatory, anti-cancer, and anti-viral drugs.

The invention relates to the technical field of nematicides, in particular to application of camellia oleifera cakes in prevention and treatment of meloidogyne incognita. The ethanol extract of the oil tea cake has high biological activity on meloidogyne incognita and has a synergistic effect with fluopyram, and the prevention effect can be remarkably improved by compounding the ethanol extract of the oil tea cake and the fluopyram. The ethanol extract of the oil tea cake has remarkable poisoning activity on meloidogyne incognita J2s, the EC50 value of the ethanol extract is reduced along with the prolonging of treatment time, and the EC50 value reaches 1.43 mg / mL when the treatment time is 72 h; an obvious inhibition effect is achieved on nematode egg incubation, and the inhibition rate of 15 mg / mL treatment at 7 days reaches 85.12%. A compounding experiment shows that when the fluopyram and the ethanol extract of the oil tea cake are prepared according to the ratio of 1: 1-9 or 3: 1, the synergistic index (CI) is less than 1, and an obvious synergistic effect is shown; in a pot experiment, the control effect on luffa rhizosphere J2s reaches 85.41% and the root knot index control effect reaches 82.06% when the luffa is treated according to the compounding ratio of 1: 5, and the control effect and the root knot index control effect are obviously superior to those of single-agent treatment.

The present invention discloses a pharmaceutical composition comprising more than 26 substances, obtained by mixing ethanol extracts of costus root, agarwood, jujube, terminalia chebula, nutmeg, kapok, and frankincense with travertine. The composition can improve myocardial ischemia in subjects; increase the ejection fraction of subjects with myocardial infarction; increase the fractional shortening of the heart; reduce the left ventricular end-diastolic diameter in subjects with myocardial infarction; reduce the left ventricular end-systolic diameter in subjects with myocardial infarction; shorten the sleep latency in subjects with insomnia; prolong the sleep duration in subjects; and upregulate the expression of GAD67 protein in the brain tissue of subjects.

The invention discloses a preparation method of a solanum photeinocarpum extract as well as a product and application of the solanum photeinocarpum extract, and belongs to the field of plant extraction. The preparation method comprises the following steps: taking solanum photeinocarpum seedlings, crushing, heating with 70% ethanol at 65 DEG C, performing reflux extraction for 3-4 times, combining extracting solutions, and performing vacuum concentration until no alcohol smell exists, thereby obtaining an ethanol extract; the preparation method comprises the following steps: mixing a water phase and an organic phase, dispersing with pure water in a ratio of 1: 1, sequentially extracting with n-hexane, dichloromethane and ethyl acetate, respectively extracting each part for 3-5 times according to a ratio of the organic phase to the water phase of 1: 1-1: 5, and recovering under reduced pressure to obtain an ethyl acetate extract which is used as the solanum photeinocarpum extract. The preparation method adopts a mild process, is safe, controllable and environment-friendly, and is suitable for industrial production. The obtained solanum photeinocarpum extract is low in toxicity and free of sensitization, has remarkable anti-oxidation, anti-inflammatory and anti-aging effects, can be applied to cosmetics such as skin care water aqua and anti-aging face cream, effectively improves the skin moisturizing rate and collagen synthesis amount, and has an anti-light aging effect.

The invention relates to the technical field of medicine, and provides a preparation method and application of a safflower seed meal ethanol extract.The method comprises the steps that after safflower seed meal is smashed, a 55%-95% ethanol solution is added according to the material-liquid ratio of 1: 5-1: 25; after soaking for 0.5-2.5 hours at room temperature, heating, refluxing and extracting for 0.5-2.5 hours at 35-75 DEG C; and repeatedly extracting once, combining filtrate, concentrating under reduced pressure, and freeze-drying. The total flavone content in the safflower seed meal ethanol extract extracted by the invention is not less than 7.4%. According to the method, a single-factor experiment design response surface is combined to optimize the extraction process of the total flavonoids of the safflower seed meal, optimal extraction conditions are found, development and utilization of the safflower seed meal are enhanced, the comprehensive utilization rate is increased, and the marginal Xinjiang economy is revitalized.

The invention discloses a high-content propolis ethanol extract soft capsule and a production process thereof. The contents comprise the following raw materials in parts by weight: 30-40 parts of a high-content propolis ethanol extract, 10-20 parts of nanoscale propolis particles, 55-65 parts of polyethylene glycol 600, 5-8 parts of optimized vegetable oil, 3-8 parts of glycerol, 1-3 parts of a suspending aid, 0.5-1.5 parts of vitamin E, 1-3 parts of nano silicon dioxide and 0.1-0.3 part of sodium citrate; and a capsule shell: 10-15 parts of gelatin, 2-5 parts of glycerol, 12-18 parts of purified water, 0.05-0.15 part of potassium sorbate and 0.1-0.3 part of titanium dioxide. The invention relates to the technical field of propolis products. According to the high-content propolis ethanol extract soft capsule and the production process, a pretreatment process of low-temperature freeze-drying, liquid nitrogen embrittlement and ultramicro wall breaking is adopted, so that propolis cell walls are thoroughly broken, and the specific surface area is greatly increased; in cooperation with a gradient ethanol extraction technology, high-polarity flavonoid and phenolic acid components are extracted by using high-concentration ethanol, and then moderate-polarity active components are extracted by using moderate-concentration ethanol, so that sufficient dissolution of the different-polarity active components is realized.

The invention relates to the technical field of Chinese arborvitae twig and leaf extracts, and discloses a Chinese arborvitae twig and leaf extract-containing anti-dandruff and itching-relieving plant composition and a preparation method thereof, and the method comprises the following steps: preparation of a Chinese arborvitae twig and leaf ethanol extract, preparation of a water phase, preparation of an oil phase, emulsification, blending and post-treatment. A multi-target synergistic effect system is constructed by carefully selecting a Chinese arborvitae twig and leaf ethanol extract, curcumin, dipotassium glycyrrhizinate and oat beta-glucan and scientifically compounding; by utilizing the antibacterial and bacteriostatic properties of the cacumen biotae ethanol extract, the anti-inflammatory and anti-oxidation characteristics of curcumin, the soothing and repairing effects of dipotassium glycyrrhizinate and the barrier protection function of oat beta-glucan, malassezia reproduction can be inhibited, scalp inflammatory response can be relieved, and the damaged scalp barrier can be repaired, so that dandruff removal and lasting itching relieving are realized; meanwhile, all the components are natural, so that scalp irritation and drug resistance risks caused by chemical synthesis components are reduced, and the mildness and long-term use safety of the product are guaranteed.

The present invention relates to a topical composition comprising a 100 μg / mL ethanolic extract from the plant Aspalathus linearis together with a dermatologically acceptable carrier for use in a method of preventing or treating a hypopigmentary disorder of skin in a subject comprising applying the topical composition to the skin of the subject. The invention further relates to methods of preventing or treating a hypopigmentary disorder of skin in a subject comprising applying the topical composition to the skin of the subject.