287 results about "Ethanol extracts" patented technology

The invention provides a streptomyces, which is named as Streptomyces sp. And is registered and preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No: 65917. The invention also provides a fermentation broth of the streptomyces, and an ethanol extract and a crude extract of the fermentation broth. The novel streptomyces, the crude extract thereof and the like have broad-spectrum antibacterial activity, have a good antagonistic effect on various pathogenic bacteria such as banana long leaf spot germs and banana colletotrichum gloeosporioides, can enable hyphae of the banana colletotrichum gloeosporioides to shrink, deform and break, inhibit spore germination of the banana colletotrichum gloeosporioides, and have a good anti-bacterial effect on the banana colletotrichum gloeosporioides. According to the present invention, with the application of the bacterial strain, the colletotrichum gloeosporioides spores are shrunk and broken, the growth of the colletotrichum gloeosporioides is inhibited, the peroxidase activity, the polyperoxidase activity, the CAT activity and the like in the banana peel can be improved, and the bacterial strain is the potential biological agent for the prevention and control of the colletotrichum gloeosporioides diseases, and has wide development space and good development and application prospects.

The invention discloses a propolis ethanol extract loaded ZIF-8 cellulose starch-based sustained-release film and a preparation method thereof, and belongs to the technical field of food preservative films. The propolis ethanol extract loaded ZIF-8 cellulose starch-based sustained release membrane is prepared from the following raw materials in parts by weight: 30 to 70 parts of starch, 30 to 70 parts of cellulose nanofiber, 7.5 to 17.5 parts of glycerol and 4 to 8 parts of filler. The starch wastewater is used as a starch raw material source, and the cellulose nanofibers loaded with ZIF-8 by the propolis ethanol extract are added, so that the prepared slow-release film is high in strength and good in toughness, can be naturally degraded after being used, reduces environmental pollution, ensures the safety of the product, has antibacterial and antioxidant effects, provides benefits for fresh keeping of fruits, and has a wide application prospect. Meanwhile, a new thought is provided for resource utilization of the starch wastewater.

The invention relates to the technical field of soil improvement, in particular to a pineapple planting soil improvement method and a special modifier thereof. According to the pineapple planting soil improvement method, the special improver for the pineapple planting soil is applied to the soil before planting, the application amount is 15-25 kg / mu, and shallow turning is conducted after application; the special modifier for the pineapple planting soil is prepared from the following raw materials in percentage by mass: 35 to 65 percent of activated carbon or loaded activated carbon, 30 to 60 percent of cake fertilizer containing nematode inhibiting substances, 0.5 to 5 percent of loaded pomegranate peel ethanol extract and the balance of adhesive. The cake fertilizer (such as cottonseed meal and tea seed meal) containing the nematode inhibiting substance is an agricultural by-product, the raw materials are easy to obtain, and the cost is low; the activated carbon can be prepared from agricultural and forestry wastes (such as coconut shell charcoal), and accords with circular economy. Meanwhile, the environment-friendly and environment-friendly pesticide is eco-friendly, biodegradable, free of chemical residues and capable of killing insects and inhibiting bacteria at the same time.

The invention provides novel application and a method of asiaticoside. The method comprises the following steps: S1, extraction: taking a centella asiatica medicinal material, performing coarse crushing, adding ethanol, performing reflux extraction, performing filtration, and combining filtrate for standby application; s2, concentrating: concentrating the ethanol extracting solution under reduced pressure until no alcohol smell exists, centrifuging, and reserving supernate for later use; s3, carrying out D101 column chromatography; s4, alumina column chromatography; s5, performing concentration; s6, drying; s7, dissolving with methanol, adding water, standing, and monitoring clear liquid and crystallization conditions in a liquid phase; s8, filtering after crystallization is finished, washing with ethanol, drying crystals under the conditions that the vacuum degree is-0.06 to-0.08 mpa and the temperature is 60-70 DEG C, and crushing and sieving dry paste to obtain asiaticoside; specifically, the new application comprises reduction of uric acid (UA), urea (UREA), creatinine (CREZ), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and total cholesterol (CHOL) in serum of a hyperuricemia model SD rat, and reduction of damage of hyperuricemia to kidney. And the yield of asiaticoside extracted by the method is high and is about 84%.

The invention discloses functional food for relieving pressure and regulating intestines and stomach and a preparation method thereof, and belongs to the technical field of functional food. The preparation method comprises the following steps: respectively pretreating spina date seeds, lily bulbs, poria cocos, Chinese yams and kudzuvine roots; mixing the pretreated poria cocos, Chinese yam and radix puerariae with germinated brown rice, hawthorn and pericarpium citri reticulatae to obtain a yeast; then adding pretreated spina date seed / lily freeze-dried powder, a polygala tenuifolia ethanol extract and fermented apple powder, uniformly mixing, then inoculating lactobacillus plantarum, and carrying out second fermentation to obtain a second fermented product; then adding inulin and gelatinized kudzuvine root starch, and uniformly mixing to obtain slurry; dropwise adding the slurry into the coating liquid, filtering to obtain microcapsule powder, then adding longan pulp powder, and uniformly mixing to obtain the functional food. According to the invention, the problems of low utilization efficiency of medicinal and edible components, poor flavor and taste, limited single effect and the like are solved, and the double-effect functional food which is safe, effective and pleasant in flavor and has clear scientific basis and market prospect is developed.

The invention discloses a saussurea involucrata culture as well as a preparation method and application thereof, and belongs to the technical field of bioengineering and medicines. The invention relates to a saussurea involucrata culture, in particular to a selenium-rich and chromium-rich saussurea involucrata cell culture with DPP-IV inhibitory activity. The content of selenium in the saussurea involucrata culture reaches 200 mg / Kg dry weight or above, and the content of chromium Cr < 3 + > reaches 20 mg / Kg dry weight or above; in addition, chromium Cr < 6 + > is not detected, and the 70% ethanol extract of the saussurea involucrata cell culture is applied to an in-vitro DPP-IV inhibition test, and the inhibition rate of the 70% ethanol extract of the saussurea involucrata cell culture reaches 99.08%. The selenium-rich and chromium-rich saussurea involucrata culture with the high DPP-IV inhibition rate can be widely applied to preparation of medicines, health foods or functional foods for preventing and / or treating type 2 diabetes, obesity and related metabolic diseases.

The invention relates to the technical field of gastrodia elata cultivation, in particular to a fungus material for gastrodia elata cultivation and a cultivation method.The fungus material contains plants capable of inhibiting pathogenic bacteria causing gastrodia elata tuber rot disease, and the fungus material is composed of, by mass, 58% of sawdust, 30% of cottonseed hulls, 10% of maytenus stems, 1% of gypsum powder, 0.5% of KH2PO4 and 0.5% of MgSO4. The fungus material provided by the invention contains the plant maytenus stems capable of inhibiting pathogenic bacteria causing the gastrodia elata tuber rot disease, the ethanol extract of the maytenus stems can efficiently inhibit the pathogenic bacteria primary verticillium atrophaeum causing the gastrodia elata tuber rot disease, and in addition, the ethanol extract of the maytenus stems has no obvious inhibiting effect on armillaria mellea; the method ensures that a gastrodia elata-armillaria mellea symbiotic system is not interfered, the field experiment control effect is 76.85% when the fungus material is used and a method for spraying the maytenus stem ethanol extract bactericide is combined, and the method has important value for ensuring sustainable development of the gastrodia elata industry.

The invention discloses a hydrogel patch for promoting blood circulation to remove meridian obstruction and a preparation method thereof. The formula of the hydrogel patch for promoting blood circulation to remove meridian obstruction comprises a traditional Chinese medicine concentrated solution for promoting blood circulation to remove meridian obstruction, an oil-in-water emulsion for promoting blood circulation to remove meridian obstruction, sodium polyacrylate, polyacrylic acid, glycerol, azone, dihydroxyaluminum aminoacetate, tartaric acid, disodium ethylene diamine tetraacetate, methylparaben and deionized water. The traditional Chinese medicine concentrated solution for promoting blood circulation to remove meridian obstruction is 70% ethanol extract of vinegar-processed rhizoma corydalis, ligusticum wallichii, philippine flemingia root, safflower, frankincense, myrrh, radix angelicae and liquorice; the oil-in-water emulsion capable of promoting blood circulation to remove meridian obstruction is prepared from a vinegar rhizoma corydalis sesame oil extract, wintergreen oil, methyl glucose sesquistearate, stearate, cetostearyl alcohol, polydimethylsiloxane and deionized water; the blood-activating collateral-dredging hydrogel patch has no skin irritation, belongs to weak sensitization, and has the function of assisting in relieving pain.

The invention discloses a preparation method of an astragalus extract with a uric acid reducing effect, and belongs to the technical field of biological medicines. The method comprises the following steps: concentrating an ethanol extract of radix astragali, extracting by using n-butyl alcohol, ethyl acetate and petroleum ether respectively, and concentrating an extract to obtain n-butyl alcohol, ethyl acetate and petroleum ether extraction parts and residual parts respectively, so as to obtain an n-butyl alcohol extract, namely the radix astragali extract for reducing uric acid. Efficacy experiments show that the normal butanol extraction part of the ethanol extract of the astragalus membranaceus can obviously reduce the serum uric acid level (SUA) of a mouse with hyperuricemia, inhibit the activity of xanthine oxidase (XOD) and effectively improve kidney injury caused by the hyperuricemia. The uric acid reducing effect of the radix astragali n-butyl alcohol extract is close to that of a clinical drug allopurinol, and the radix astragali n-butyl alcohol extract has wide development and application prospects in the aspect of relieving hyperuricemia.

The invention relates to the field of natural medicines, and discloses an alkaloid and a preparation method and application thereof, and the alkaloid has a structure as shown in a formula I and a pharmaceutically acceptable salt thereof. The alkaloid is separated from an n-butyl alcohol extraction part of a dendrobium huoshanense stem ethanol extract through silica gel column chromatography and a preparative thin-layer separation technology, and the structure of the alkaloid is identified through nuclear magnetic resonance and high-resolution mass spectrometry. Cell experiments prove that the alkaloid prepared by the invention can remarkably relieve inflammation induced by LPS, inhibit proliferation of human gastric cancer cells (AGS) and promote apoptosis of the AGS; molecular docking analysis shows that the alkaloid prepared by the invention can be remarkably docked with active sites of inducible iNOS, IL-6, TNF-alpha and MMP9, and the binding energy is 9.5-8.6 kcal / mol.

The invention provides a method for rapidly detecting the ABTS < + > free radical scavenging rate of a traditional Chinese medicine extract based on Fourier infrared spectroscopy, which comprises the following steps: (1) collecting the Fourier infrared spectroscopy of a dandelion ethanol extract, and measuring the true value of the ABTS < + > free radical scavenging rate corresponding to the Fourier infrared spectroscopy by using spectrophotometry; (2) preprocessing the collected Fourier infrared spectrum to obtain a preprocessed spectrum; (3) carrying out characteristic wavelength variable extraction on the preprocessed spectrum by adopting a VIP algorithm, and combining spectrum segments corresponding to extracted characteristic wavelengths into a characteristic spectrum; (4) performing PCA analysis and step length segmentation processing on the characteristic spectrum to obtain an angle characteristic vector alpha y, and forming an angle characteristic matrix alpha by the angle characteristic vectors of all the traditional Chinese medicine extracts; and (5) constructing a regression model by using the angle feature vector matrix alpha. Compared with a traditional spectrophotometric detection method, the method has the advantage that the accuracy and the stability of a detection result can be better improved.

The invention belongs to the technical field of microorganisms, and particularly discloses an ethanol phase extract of rumex madaio roots and application of the ethanol phase extract. An ethanol phase extract RmEE is extracted from rumex madaio roots through a 55-95% ethanol solvent extraction method, and the ethanol phase extract RmEE is further separated and purified to obtain a purified component RmEE-F2. The ethanol phase extract RmEE and the purified component RmEE-F2 of the ethanol phase extract RmEE can inhibit staphylococcus aureus and vibrio cholerae, and can be used as bacteriostatic agents. The ethanol phase extract of the rumex madaio root can inhibit the pollution of staphylococcus aureus and vibrio cholerae in meat of crucian and penaeus vannamei which are stored at low temperature (4 DEG C), and can be applied to aquatic products; the method can also be used for preparing food or medicines, and the prepared food or medicines also have an antibacterial effect.

This invention discloses a method for determining the components of an ethanol extract of *Clerodendrum trichotomum* leaves. A liquid chromatography-mass spectrometry (LC-MS) method was established to detect the content of the ethanol extract. Raw data acquired by mass spectrometry was retrieved using software and compared with a mass spectrometry database to identify the chemical components of the ethanol extract. Ultimately, 44 chemical components were detected in the ethanol extract, providing a basis for the quality and efficacy evaluation of *Clerodendrum trichotomum* medicinal materials.

The invention provides a traditional Chinese medicine composition with anti-inflammatory and analgesic effects as well as a preparation method, application and a medicine thereof, and relates to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 30-55 parts of pseudo-ginseng, 26-40 parts of notopterygium root, 15-35 parts of safflower, 15-35 parts of berba aristolochiae mollissimae, 20-40 parts of liquorice, 10-20 parts of acanthopanax and 10-30 parts of dandelion. Performing reflux extraction on the pseudo-ginseng, the notopterygium root, the safflower and the dandelion by using an ethanol solution to obtain an ethanol extracting solution and medicine residues; mixing the medicine residues, berba aristolochiae mollissimae, liquorice and acanthopanax, decocting with water, and then carrying out microwave treatment to obtain a water extracting solution; combining the ethanol extracting solution and the water extracting solution, and drying to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition disclosed by the invention has synergistic effects of diminishing inflammation, easing pain and diminishing swelling; when the compound is applied to medicine preparation, the obtained medicine can remarkably reduce the pain degree and the osteoarthritis index and improve the joint motion range.

A method for improving skin elasticity includes use of a composition containing an ethanol-extracted product of Aronia melanocarpa fruit and Bifidobacterium longum CB108 which is deposited at the Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH under an accession number DSM 33895 in accordance with the Budapest Treaty.

The present invention discloses a sesquiterpene glycoside compound and its preparation method and application. A new sesquiterpene glycoside ligulariatinside A is isolated and identified from the n-butanol extraction part of 95% ethanol extract from the root of Ligularia glossata by multiple chromatographic methods such as macroporous resin column chromatography, positive and reverse phase silica gel column chromatography and high performance liquid chromatography, as well as spectral methods. The molecular formula of the new sesquiterpene glycoside ligulariatinside A is determined to be C 21 H 34 O7, the structure is (3 S ,4 R ,5 R ,7 R )‑11‑hydroxy‑11,12‑dihydronootkatone‑11‑ O ‑ β ‑D‑glucopyranoside enriches the chemical diversity of Ligularia officinalis. Bacterial inhibition experiments revealed that the new sesquiterpenoid glycoside exhibits inhibitory activity against Vibrio anguillarum, with a minimum inhibitory concentration (MIC) of 50 μg / mL, laying the foundation for the development of new antibacterial drugs.

The application discloses a preparation method of ethanol extract of Drynaria Rhizome and application thereof. The method comprises the following steps: crushing and sieving Drynaria Rhizome, adding ethanol, reflux extraction, combining filtrates, vacuum concentration and drying, and thus the ethanol extract of Drynaria Rhizome is obtained. The in-vitro alpha-glucosidase enzyme inhibition experiment shows that the ethanol extract of Drynaria Rhizome has a significant inhibitory effect on alpha-glucosidase enzyme, and the IC 50 is about 142.68 μ g / mL. Therefore, the ethanol extract of Drynaria Rhizome can be used for preparing a hypoglycemic drug, health care product or functional food, and has a wide application prospect.

Natural turmeric and hibiscus inks were developed for use on fabrics and writing surfaces. Ethanolic extracts of turmeric and hibiscus were obtained and formulated with environmentally friendly mordants such as ferrous sulfate, ascorbic acid, and apple cider vinegar, and thickeners such as linseed oil and aloe vera. These treatments were tested on fabric, filter paper, and notebook paper. Color and color loss were evaluated using the Paint program when exposed to sunlight and washing (in the case of fabric), comparing the RGB and Hex pixel values ​​obtained before and after sun exposure and washing. The degree of similarity was assessed using a digital Color Matcher Tool with the Hex and RGB data. Once the best treatment with the aforementioned mordants was determined, the ink formulation was developed using thickeners such as gelatin, alginate, cornstarch, and honey.It has a pleasing color and good consistency for use on fabric and paper. It's possible to create inks for writing and dyeing fabrics with readily available ingredients, thus contributing to environmental protection.

This invention relates to the field of natural product chemistry, specifically to the application of a *Syzygium brevicornum* leaf extract in the preparation of drugs for the prevention and / or treatment of atherosclerosis. The preparation method of the *Syzygium brevicornum* leaf extract of this invention includes the following steps: taking dried *Syzygium brevicornum* leaves, extracting with ethanol solution, filtering, combining the extracts, and concentrating under reduced pressure to obtain a total extract of *Syzygium brevicornum* leaf ethanol extract; extracting the total extract of *Syzygium brevicornum* leaf ethanol extract with ethyl acetate to obtain the *Syzygium brevicornum* leaf extract. Using the RAW264.7 foam cell model, this invention found that the *Syzygium brevicornum* leaf extract prepared by this invention can reduce lipid accumulation in RAW264.7 macrophage-derived foam cells, suggesting that the *Syzygium brevicornum* leaf extract prepared by this invention can be used to prepare drugs for the prevention and / or treatment of atherosclerosis.

The invention relates to a preparation method and application of an effective part of hyssop officinalis L. The method comprises the following steps: taking hyssop officinalis L., cutting into cun sections, carrying out reflux extraction with ethanol, filtering, merging filtrates, carrying out vacuum concentration, and carrying out vacuum drying to obtain a hyssop officinalis L. ethanol extract; and dissolving the extract in ethanol, extracting with ethyl acetate, concentrating the upper layer under reduced pressure, and drying in vacuum to obtain the effective part of hyssop officinalis. The invention further discloses application of the effective part of the hyssop officinalis obtained through testing in preparation of the anti-allergic asthma medicine.

The present application relates to a kind of blended fabric segmented steaming fixation method, comprising the following steps: blended fabric is sequentially carried out desizing, kiering, bleaching and mercerizing treatment, and pretreatment blended fabric is obtained after drying;Using composite reagent on pretreatment blended fabric is carried out padding treatment or vacuum-assisted foam impregnation treatment, and pre-treatment blended fabric is obtained after hot air drying;Prepare dye liquor, and after using dye liquor on pre-treatment blended fabric is carried out dye liquor padding treatment, then carry out segmented steaming fixation treatment, and after sequentially washing, drying, setting, obtain dyed blended fabric.The present application uses the composite reagent containing Ageratina pichurini ethanol extract and simmondsia chinensis seed oil to carry out padding treatment or vacuum-assisted foam impregnation treatment on blended fabric before dyeing, then carries out segmented steaming fixation treatment, can significantly improve the tensile strength and wash fastness of blended fabric, while giving blended fabric good gloss, and can make blended fabric keep better perspiration fastness.

The invention discloses a mosquito prevention and control composition based on jonquil extract and application of the mosquito prevention and control composition. The invention provides an application of an ethanol extract of jonquil leaves in killing mosquitoes or preparing products for killing mosquitoes. The invention firstly proves that the kalanchoe blossfeldiana ethanol extract has a killing effect on three mosquito species, and the killing effect is obviously superior to that of kalanchoe laciniata which is the same family plant. The invention further provides a mosquito prevention and control composition containing the ethanol extract of the jonquil leaves and a mosquito prevention and control compound composition containing the ethanol extract of the jonquil leaves and dinotefuran. The insecticide poison bait prepared by compounding the jonquil extract and the chemical insecticide provides a new thought for constructing an efficient, low-consumption and environment-friendly mosquito comprehensive treatment system, and is suitable for comprehensive prevention and control of mosquito-borne diseases.

The invention discloses an inclusion method of the alcohol extract of Ligusticum chuanxiong, belonging to the technical field of medicines, and solves the problems of easy sticking to punches, pitting, and large dosage of excipients in the prior art. The inclusion method of the alcohol extract of Ligusticum chuanxiong of the invention comprises the following steps: under stirring conditions, an ethanol solution of the alcohol extract of Ligusticum chuanxiong is dropped into a saturated solution of hydroxypropyl-β-cyclodextrin for inclusion, refrigeration, filtration, and low-temperature drying to obtain an inclusion compound. The invention first uses hydroxypropyl-β-cyclodextrin to include the ethanol extract of Ligusticum chuanxiong, and the obtained inclusion compound has significantly accelerated dissolution in vitro. When used for preparing tablets, the dosage of excipients is small, there is no sticking to punches, the obtained tablets have good appearance, and all quality indexes meet the requirements. The method of the invention is simple, easy to operate, and has high inclusion rate and high yield, and is suitable for industrial production.

The present invention discloses a scutellarin extract and a preparation method thereof. By combining the aqueous solution obtained by removing ethanol from the water extract or ethanol extract of the dried whole herb of the plant of the genus Erigeron in the Compositae family with the water extract of the stem and / or leaf of Scutellaria baicalensis, a scutellarin extract can be obtained, where 60% ≤ the scutellarin content < 100 wt%. The plant of the genus Erigeron in the Compositae family is selected from any one or more of Erigeron breviscapus, Erigeron multiradiatus, Erigeron elongatus, Conyza canadensis, and Erigeron acer. The water extract of the stem and / or leaf of Scutellaria baicalensis can efficiently enzymatically convert scutellarin (baicalin) in the aqueous solution obtained by removing ethanol from the water extract or ethanol extract of the dried whole herb of the plant of the genus Erigeron in the Compositae family into scutellarin aglycone (scutellarin). The present invention uses the plant of the genus Erigeron in the Compositae family as the raw material for preparing scutellarin, and fully utilizes the stems and leaves of Scutellaria baicalensis, reducing the cost of producing scutellarin; the content of scutellarin in the product obtained by the preparation method is high, and the production process is simple and feasible.

The application discloses an immune function enhancing composition which is mixed by sambucus williamsii alcohols extract and lactobacillus rhamnosus agent. The application can effectively immunize the spleen, improve the spleen index and thymus index, has the function of immune regulation, and can also improve the IgM and IgG content in serum.

The invention relates to the technical field of modernization of traditional Chinese medicines, in particular to a nano-vesicle, a preparation method and application of the nano-vesicle in preparation of an endometrial injury repairing medicine. The preparation method comprises the following steps: taking a periplaneta americana ethanol extracting solution, and adding a buffer solution to prepare diluted homogenate; performing differential centrifugal treatment on the homogenate; filtering the supernatant obtained by the differential centrifugation treatment, and then centrifuging for 60-120 minutes by 100000g of the supernatant to obtain a precipitate; and re-suspending the precipitate to obtain the periplaneta americana ethanol extract source nano-vesicles. The periplaneta americana ethanol extract is used as a starting material to enrich the nano-vesicles for the first time, the combined process of differential centrifugation, membrane filtration and ultracentrifugation is adopted, the obtained nano-vesicles can be applied to the field of endometrial injury repair, especially treatment of gynecological diseases such as intrauterine adhesion and infertility with thin intima, and the blank in the technical field is filled.

The present application provides a kind of streptomyces, named Streptomyces sp., is registered and preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No:65917.The present application also provides fermentation broth of the streptomyces and ethanol extract and crude extract of fermentation broth thereof.The new species of streptomyces and its crude extract and the like of the present application have broad-spectrum antibacterial activity, have good antagonism to many pathogenic bacteria such as banana long-shaped spot fungus and banana anthracnose fungus, and can make banana anthracnose fungus hyphae wrinkle, deform, break, inhibit banana anthracnose fungus spore germination, make banana anthracnose fungus spore germination wrinkle, break, inhibit banana anthracnose fungus growth, and can also improve peroxidase, polyperoxidase, CAT activity and the like in banana peel, is a potential biological agent for preventing and treating anthracnose disease, stem rot disease and the like, has broad development space, and has good development and application prospect.

The invention discloses a traditional Chinese medicine monomer composition derived from chrysanthemum plants and used for treating diabetic retinopathy as well as a preparation method and application of the traditional Chinese medicine monomer composition. The traditional Chinese medicine monomer composition prepared from the chrysanthemum plant as the raw material is high in safety, small in side effect and definite in component and is prepared according to a specific ratio, and pharmacodynamic experiments prove that compared with an ethanol extract, the traditional Chinese medicine monomer composition is more remarkable in curative effect on diabetic retinopathy, and the curative effect of the traditional Chinese medicine monomer composition on diabetic retinopathy is better than that of a traditional Chinese medicine composition on diabetic retinopathy. The composition can improve the pathological state of diabetic retinopathy from multiple targets and multiple ways, specifically can inhibit body mass increase caused by high glucose, reduce blood glucose level, improve retinal tissue structure damage, recover retinal tissue thickness, inhibit retinal cell apoptosis and inflammatory response, reduce the expression level of HIF-1alpha and VEGF protein in retinal tissue, and can be used for treating diabetic retinopathy. Scientific basis and technical support are provided for research and development of novel drugs for treating the diabetic retinopathy, and important clinical significance and market application prospects are achieved.

The invention provides a high-stability black wolfberry fruit lipid-regulating oral liquid and a preparation method thereof, and relates to the technical field of medicines. The semen cassiae and fructus lycii lipid-regulating oral liquid is prepared from semen cassiae ethanol extract, mixed water extract, aromatic water, a flavoring agent, a bacteriostatic agent, a pH regulator and a solubilizer. By optimizing the preparation process, the provided black wolfberry fruit lipid-regulating oral liquid is under the action of the specific flavoring agent, the bacteriostatic agent, the pH regulator and the solubilizer, the solubilizer is polyethylene glycol 400 or a mixture of polyethylene glycol 400 and polyethylene glycol 600, the content degradation speed of stilbene glucoside is obviously slowed down, the validity period of the product is prolonged from 18 months to 24 months, and the stability of the product is improved.

The invention relates to a dictyophora rubrovolvata fresh-keeping method and fresh-keeping powder used by the same. The fresh-keeping powder is prepared from the following raw materials in percentage by mass: 0.1-1% of ethanol extract of bacilli of dictyophora rubrovolvata, 5-30% of bacilli polysaccharide, 10-50% of chitosan and 20-85% of corn starch (2-8% of calcium chloride is added). The powder provided by the invention contains dictyophora rubrovolvata mycosterol, terpene and polysaccharide substances, contains low-acetyl-degree chitosan with strong antibacterial ability and certain water solubility, and absorbs moisture of the dictyophora rubrovolvata body after being contacted with the newly picked dictyophora rubrovolvata, acidic mycosterol with negative charges and alkaline low-acetyl-degree chitosan with positive charges are subjected to electrostatic adsorption reaction, so that the moisture of the dictyophora rubrovolvata can be absorbed, and the moisture of the dictyophora rubrovolvata can be absorbed; the components are mutually attracted to form a local film, so that the moisture of the mushroom body can be locked, the mass loss and hardness reduction can be relieved, the freshness can be kept through oxidation resistance and bacteria resistance, the peroxidation degree of film lipid can be relieved, the cell integrity can be maintained, and the retention rate of nutrient substances such as reducing sugar and soluble protein can be effectively increased.