The invention discloses a traditional Chinese medicine formula for decreasing serum uric acid. The traditional Chinese medicine formula for decreasing the serum uric acid comprises the following medicinal materials in parts by weight: 25-35 parts of cornu bubali, 20-25 parts of adhesive rehmannia dried root, 10-15 parts of Chinese herbaceous peony, 10-15 parts of astragalus membranaceus, 8-13 parts of moutan bark, 10-14 parts of golden cypress, 10-15 parts of radix bupleuri, 10-15 parts of cape jasmine fruit, 10-15 parts of scutellaria baicalensis, 15-20 parts of grifola, 19-25 parts of orangepeel, 8-13 parts of ginger peel, and 30-45 parts of myotonin. According to the traditional Chinese medicine formula for decreasing the serum uric acid, cornu bubali, adhesive rehmannia dried root, radix paeoniae alba, moutan bark, astragalus membranaceus, radix bupleuri, golden cypress, scutellaria baicalensis, cape jasmine fruit, orange peel, grifola, myotonin and ginger peel are used as the rawmaterials and combined by ratio and then are processed into particles through certain processes; patients eating the formula are low in serum uric acid concentration; the recurrence rate is low; theformula is safe, and free from side effects.