57results about How to "Good lipid-lowering effect" patented technology

The present invention is new recipe and preparation process of blood fat reducing medicine. The recipe of blood fat reducing medicine consists of red yeast preparation and phytosterol, or red yeast preparation and phytosterol ester, or red yeast preparation, phytosterol and other compound, or red yeast preparation, phytosterol and other mixture. The present invention can reduce the synthesis of cholesterol in liver and inhibit the absorption of cholesterol in intestinal tract, has high curative effect and is safe to human body.

Belonging to the field of medical technologies, the present invention discloses application of aloe-emodin in preparation of drugs reducing blood lipid and liver lipid. Specifically, blood lipid refers to total cholesterol and low density lipoprotein in serum, and liver lipid refers to total cholesterol in liver. Toxicity tests show that aloe-emodin has no obvious toxic and side effect. Pharmacodynamic tests of aloe-emodin show that aloe-emodin can significantly reduce the total cholesterol and low density lipoprotein in hyperlipidemia animal model serum, and has obvious blood lipid reducing effect. At the same time, aloe-emodin can also significantly reduce the total cholesterol content of a hyperlipidemia animal model liver, and has obvious liver lipid reducing effect. Therefore, the invention puts forward the application of aloe-emodin in reduction of blood lipid and liver lipid, aloe-emodin has the characteristics of significant lipid reducing effect, low toxicity, no irritation, low price, and convenient production, transportation, storage and taking, and can have broad application prospects as a blood lipid and liver lipid reducing drug.

Disclosed is a health tea for treating diabetes wherein the constituents include kudzuvine root 10-15g, root of Chinese trichosannthes 5-60g, hairy vein agrimony 1-20g, Chinese pulsatilla root 5-50g, cogongrass rhizome 1-20g, and wofberry bark 10-60g.

The invention discloses a diisopropylamine fenofibrate, a preparation method of the same, a medicinal composition and use of the same, relating to the field of medicaments for lowering blood fat and treating fatty liver. The problems that fenofibric acid products is poor in water solubility, has toxic and side effects and the like in the prior art are solved. A product of the invention is obtained through the following steps of: adding a fenofibric acid and diisopropylamine into a solvent, heating to 35-70 DEG C, cooling, separating out a solid, pumping a filtrate, washing the solid with ether, and drying to obtain a white solid which is the diisopropylamine fenofibrate. A diisopropylamine part in the invention can overcome the side effect that the fenofibric acid is heated to be converted into ammonia enzyme and blood sugar and exerts a synergetic effect of lowering the blood fat together with fenofibrate.

The invention relates to the manufacturing field of food and drugs, and discloses a green coffee bean extract sustained-release tablet. The green coffee bean extract sustained-release tablet comprises the following components: 20%-50%wt of green coffee bean extract, 10%-40%wt of hydroxy propyl methyl cellulose (HPMC), 0.2%-4.0%wt of lubricating agent, 2.0%-4.0%wt of stomach-soluble film coating powder and the balance of excipient. The invention further discloses a preparation method of the sustained-release tablet. The green coffee bean extract sustained-release tablet has the advantages of better weight loss effect, slight uncomfortableness after orally taking and high application value.

The invention relates to an omega-3 fish oil soft capsule. The omega-3 fish oil soft capsule comprises a core material and a capsule material, wherein the core material is prepared from the following components in part by weight: 40-70 parts of EPA (eicosapntemacnioc acid), 78-192 parts of DHA (docosahexaenoic acid), 15-32 parts of ginkgo leaf, 14-28 parts of acanthopanax root, 16-35 parts of pseudoginseng, 15-21 parts of salvia extract, 20-45 parts of anthocyanin, 35-68 parts of natural vitamin E, 24-49 parts of soybean oil, 21-56 parts of lecithin and 15-34 parts of arachidonic acid. The capsule material is prepared from the following components in part by weight: 10-15 parts of gelatin, 8-16 parts of glycerine, 4-8 parts of purified water, 3-9 parts of edible emulsifier and 4-9 parts of edible pigment. The Chinese herbs pseudoginseng, acanthopanax root, ginkgo leaf, salvia and the like have the functions of promoting blood circulation, eliminating blood stasis, inhibiting platelet aggregation, regulating blood lipid and the like, the EPA and the DHA extracted from deep-sea fish oil also have significant blood lipid-lowering effect, the vitamin E and the anthocyanin have a significant antioxidant effect, and the components are combined in certain part by weight, so that the omega-3 fish oil soft capsule has a significant blood lipid-lowering effect and can protect heart and brain blood vessels well to avoid cardiovascular events caused by long-term lipid disorder.

The invention relates to a traditional Chinese medicine preparation with a blood fat reducing effect, which is prepared from traditional Chinese medicines such as hawthorn extract, functional red yeast rice and gypenosides, has the efficacies of reinforcing the spleen to promote digestion, removing dampness to eliminate phlegm and promoting blood circulation by removing blood stasis, and is used for treatment of hyperlipemia as well as auxiliary treatment of coronary heart disease, hyperlipemia, other cardiovascular and cerebrovascular diseases caused by atherosclerosis and hypertension. Proven by experimental results, the traditional Chinese medicine preparation can effectively reduce the contents of total cholesterol (TC), triglyceride (TG) and low density lipoprotein (LDL) in blood, regulates lipid metabolism in blood, reduces the concentration of plasma lipid, has the health care function of reducing blood fat, is safe without side effect, and can be taken for a long time.

The invention discloses a preparation method of monascus tartary buckwheat rich in functional factors. The method comprises the following steps: (1) culturing a strain; (2) preparing a spore suspension; (3) preparing monascus spore powder; (4) preparing tartary buckwheat culture medium; (5) preparing first-stage fermented seeds; (6) preparing second-stage fermented seeds; and (7) fermenting monascus tartary buckwheat: inoculating the fresh tartary buckwheat culture medium with second-stage fermented seeds with the inoculation amount of 20-30%, transferring the inoculated material to a next-stage fermentation tank, adding a lovastatin-inducing agent, conducting uniform mixing, conducting fermentation at 28-30 DEG C for 8 days, and conducting stoving at 60 DEG C to obtain the monascus tartary buckwheat. The method has short preparation period. The monascus tartary buckwheat prepared by the method has a significantly-improved lipid-lowering effect, has rich nutritional value and functional ingredients, and is convenient to eat and good in flavor.

The invention discloses a compound product with a fat-reducing function. The compound product is prepared from the following raw materials: soybean peptide, wheat oligopeptide, mulberry leaf powder, plant dietary fiber, soybean lecithin and compound vitamins, wherein the compound vitamins comprise vitamin A, vitamin D3, vitamin E, vitamin B1, vitamin B2, vitamin B12, vitamin C, folic acid, biotin,nicotinamide, beta-carotene, inositol and taurine. The compound product disclosed by the invention has the advantages that the contents of total cholesterol, triglyceride and low-density lipoproteinin blood can be effectively reduced and the content of high-density lipoprotein is increased.

The invention discloses weight losing herbal tea. The weight losing herbal tea is prepared from, by mass, 40-55 parts of Chinese herbal medicine common extract, 8-15 parts of laminarin and 4-8 parts of lemon pectin. The Chinese herbal medicine common extract is prepared from 20-35 parts of watermelon peel, 10-23 parts of mulberry leaves, 18-28 parts of hawthorn fruits, 6-12 parts of radix polygoni multiflori, 8-15 parts of dried tangerine or orange peel and 16-28 parts of poria cocos through common extraction. The medicinal and edible Chinese herbal medicine is selected, and watermelon peel, mulberry leaves, hawthorn fruits, radix polygoni multiflori, dried tangerine or orange peel and poria cocos have the effects of cooling and dampness removal. Laminarin and lemon pectin are further added into the weight losing herbal tea, laminarin has a good fat reducing effect, fat in chyme can be taken out of the body, and therefore absorption of the organism on fat in food is reduced. Laminarin also has the healthcare effect of reducing blood sugar; lemon pectin serves as soluble dietary fibers, and can improve the intestinal tract bacterial colony environment and reduce absorption of the intestinal tract on fat.

The invention is concerned with the method of preparation of the compound medicine for fatty liver and chemistry damage liver therapy that made of red cube and fructus schizandrae.

The invention discloses a gliclazide sustained release tablet and a preparation method thereof. The tablet is composed of a sustained release layer and an auxiliary layer with the weight ratio of 1-2:0.6-1.2. The sustained release layer comprises, by weight, 88-132 parts of gliclazide, 220-330 parts of skeleton material, 120-180 parts of sustained release layer filler, 4-6 parts of sustained release layer adhesive and 3-4.5 parts of slow release layer lubricant. The auxiliary layer comprises, by weight, 28-42 parts of hydroxymethylglutaryl-coenzyme A reductase inhibitor, 27-40.5 parts of montmorillonite, 20-30 parts of fruit and vegetable powder, 24-36 parts of auxiliary layer adhesive, 3.5-5.25 parts of vitamin C, 1.6-2.4 parts of deionized water and 2-3 parts of auxiliary layer lubricant. The gliclazide is combined with a drug for lowering blood lipids, a drug for treating diarrhea and a nutrient substance used by diabetic patients to make the tablet to significantly increase the hypoglycemic effect of the gliclazide, and adverse reactions such as hypoglycemia and diarrhea are not easy to cause.

The invention relates to a traditional Chinese medicinal composition for preventing and treating fatty liver, wherein the composition comprises Monascus color extract, schisandra fruit extract and Silybum marianum extract.

The invention discloses a health capsule by using concentration fruit juice as the principal capsule liquid, which comprises capsule liquid and capsule casing, wherein the capsule liquid is prepared from one or more concentration fruit juices, the concentration fruit juice can be treated through desugarizing or not.

The invention provides a non-total nutrient special medical food with a blood fat reducing effect and a preparation method thereof, and belongs to the technical field of special medical foods. The special medical food is prepared from the following raw materials in parts by weight of 20-70 parts of red yeast rice vinegar, 30-60 parts of fresh fruit and vegetable juice, 20-50 parts of a traditionalChinese medicinal material extracting solution, 3-5 parts of xylitol, 0.001-0.01 part of potassium sorbate and 0.01-0.05 part of lactobacillus plantarum. The special medical food produced by taking the red yeast rice vinegar and the lactobacillus plantarum as raw materials has the health-care functions of reducing blood pressure, reducing blood fat and the like, and is high in pertinence. Juice of celery, onions, garlic, shiitake mushrooms, Chinese yams, apples and kiwi fruits, leach liquor of cassia seeds, hawthorn fruits, lotus leaves, honeysuckle flowers, kudzuvine roots, chrysanthemums and green tea and red yeast rice vinegar stoste are blended, the taste is good, the flavor is special, and meanwhile the lipid-lowering activity of the red yeast rice vinegar is enhanced.

The invention relates to preparation of a composition having the effect of assisting in reducing blood lipid. The composition comprises the following components in parts by weight of 2-50 parts of chenopodium quinoa willd powder, 1-30 parts of soybean protein powder, 0.1-2 parts of spirulina powder, 0.1-2 parts of a natto extract and 0.1-2 parts of a bitter gourd extract. In a preferred scheme, 0.0001-0.001 part of a folic acid compound, 0.1-3 parts of green tea powder and 0.1-3 parts of corn stigma powder are also added to the composition. The composition disclosed by the invention can be used for preparing various preparations having the effect of assisting in reducing blood lipid. The composition not only has obvious efficacy of assisting in reducing the content of total cholesterol (TC) and triglyceride(TG) in serum, and increasing the content of high density lipoprotein cholesterol (HDL-C), but also has the advantages of being long in storage time and small in side effects, and issuitable for various crowds of various ages to use.

The invention discloses a monascus strain capable of high yielding Monacolin K. The strain is a monascus strain, which has a collection number of CGMCC No. 14786 or CGMCC No. 14787 and is collected inGeneral Microorganisms Center of China Committee for Culture Collection of Microorganisms. The invention further discloses application of the strain. The strain disclosed by the invention is high inMonacolin K yield and has a good market application prospect.

The invention discloses a production method and an application of coix seed, red yeast rice and lotus leaf functional granulated tea. The production method comprises the steps of monascus strain spore suspension preparation, coix seed boiling, cooling, red yeast rice mixing and fermenting, lotus leaf tea submicron powder preparation, granulation and gradient baking. The coix seed, red yeast rice and lotus leaf functional granulated tea product produced in the invention facilitates efficacy factor leaching and boiling drinking of the product, and the leaching rate and the leaching speed of effective components of the product are improved by 37.2% and 232.5% respectively; the product can be stirred in boiling powder to form a paste for direct eating, and avoids rough mouthfeel after entering the human oral cavity; and the product can be added to other foods as a functional food ingredient without influencing the quality of products, for example, the product can be added to steamed breads, noodles, cakes and beverages to exploit a series of healthy foods.

The invention relates to the technical field of functional beverages, and discloses thallus laminariae oolong tea capable of reducing fat for teenagers, and a preparation method of the thallus laminariae oolong tea. The thallus laminariae oolong tea consists of the following raw materials in parts by weight: 0.2-0.4 part of oolong tea leaves, 0.2-0.5 part of laminarin, 7-10 parts of watermelon juice, 4-8 parts of white granulated sugar, 0.04-0.06 part of L-ascorbic acid, 0.03-0.05 part of beta-cyclodextrin, 0.03-0.06 part of citric acid, 0.1-0.5 part of sodium chloride, 0.005-0.015 part of potassium dihydrogen phosphate, 0.002-0.003 part of calcium gluconate, 0.003-0.005 part of magnesium sulfate, 0.001-0.005 part of zinc citrate, 0.0001-0.002 part of sodium selenite, 0.05-0.1 part of composite vitamins and the balance of water, wherein all of the raw materials are 100 parts . According to the thallus laminariae oolong tea disclosed by the invention, based on the growth and developmentlaw of the teenagers strictly, comprehensive ample nutrient substances are provided for the teenagers in a scientific and pointed manner, so that intake of the teenagers for fat and cholesterol is reduced, the functions of digestive tracts of the teenagers are improved, and the thallus laminariae oolong tea has the effects of reducing fat and eliminating fat, contributes to preventing the teenagers from obesity and can improve the learning efficiency and the living quality of the teenagers.

The invention relates to a composition capable of curing abnormal blood lipid. The composition capable of curing the abnormal blood lipid comprises ezetimibe, atorvastatin calcium and acipimox. The range of weight ratios of the ezetimibe, the atorvastatin calcium and the acipimox in the composition is 5-10: 5-80: 250-1000, preferably 10: 10-40: 250-750 and optimally, 10: 10-20; 500-750. The composition capable of curing the abnormal blood lipid is strong in blood lipid regulating effect, comprehensive in function and little in side effect.

The invention discloses a health-caring product for preventing and treating hyperglycemia and hyperlipidemia of a diabetic patient and a preparation method thereof. The preparation method includes steps of mixing, drying and crushing red yeast rice powder, a tartary buckwheat extract and a mulberry fruit juice. The preparation method is simple. By means of lovastatin in the red yeast rice powder, total flavonoids in the tartary buckwheat extract, 1-deoxynojirimycin in mulberry fruits and components such as various amino acids in a formula, blood glucose and blood fat can be inhibited or reduced. According to the formula, three raw materials are employed cooperatively so that a blood glucose reducing effect and a blood fat reducing effect can be improved. In addition, the mixture composed of the red yeast rice powder, the tartary buckwheat extract and the mulberry fruit juice provided in the invention can be used as a raw material. With addition of pharmaceutically acceptable auxiliary materials or components, the raw material can be prepared into tablets, capsules, granules, granular tea, or the like. The health-caring product has a huge medicinal and health-caring value.

The invention discloses a weight-losing cream herbal tea. The weight-losing cream herbal tea comprises the following components of 10 to 15 parts of Chinese herbal medicine common extract, 8 to 12 parts of laminarin, 4 to 8 parts of citrus pectin, and 35 to 45 parts of agar, wherein the Chinese herbal medicine common extract is prepared by extracting 20 to 35 parts of water melon extract, 10 to 23 parts of mulberry leaf, 18 to 28 parts of fructus crataegi, 6 to 12 parts of radix polygoni multiflori, 8 to 15 parts of dried orange peel, and 16 to 28 parts of poria cocos. The weight-losing cream herbal tea has the advantages that by elaborately selecting the water melon extract, the mulberry leaf, the fructus crataegi, the radix polygoni multiflori, the dried orange peel and the poria cocos, the effects of cooling and removing dampness are realized; by adding the laminarin and the citrus pectin, the citrus pectin has good effect of decreasing lipid, and can carry the fat in chyme out of human body, so that the activity of human body absorbing the fat in foods is decreased; the laminarin also has the health-care effect of decreasing blood glucose; the citrus pectin can be used as soluble dietary fiber, and be used for improving the intestinal bacterial colony environment, and decreasing the activity of intestinal traces absorbing fat.

A rosemary-containing composition, a preparing method thereof and applications of the composition are disclosed. The composition includes, by weight, 20-100 parts of rosemary, 10-20 parts of phytosterol, 10-30 parts of tomato seed oil and 10-30 parts of diacylglycerol. The composition is used for adjusting human body blood fat metabolism. The rosemary, the phytosterol, the tomato seed oil and the diacylglycerol which are raw materials are free of incompatibility so that safety can be fully ensured. The composition is adopted as a diet control means, and after the composition is eaten, through adjusting human body blood fat metabolism, occurrence and development of dyslipidemia can be prevented and treated, the risk of atherosclerotic cardiovascular and cerebrovascular diseases is reduced, and quality of life of people with some diseases is improved.

The invention relates to the technical field of natural medicinal chemistry and particularly relates to a dammarane type triterpenoid saponin compound separated from gynostemma pentaphylla in Hunan and Guangxi production places, and application of the dammarane type triterpenoid saponin compound in preparation of a medicine for inhibiting PCSK9 from playing a role in lowering lipid. Part of monomeric compounds in gynostemma pentaphylla in Hunan and Guangxi places of origin have different degrees of inhibitory activity on PCSK9 secreted by hepatocytes, so the purpose of independently lowering lipid or enhancing the lipid lowering effect of gynostemma pentaphylla in Hunan and Guangxi places of origin is achieved.