Traditional Chinese medicine preparation with blood fat reducing effect

A traditional Chinese medicine preparation, a technology for lowering blood lipids, applied in the directions of medical preparations, drug combinations, and pharmaceutical formulas containing active ingredients, and can solve problems such as unsuitability for long-term use, influence, etc.

Inactive Publication Date: 2011-09-07
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, chemically synthesized statins are not suitable for long-t

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1 soft capsule

[0040] Hawthorn extract 60g Functional red yeast rice 275g Gypenosides 60g

[0041] The hawthorn extract is prepared by the following method: add hawthorn to 65% ethanol with a mass concentration 8 times the weight of hawthorn, heat and reflux for extraction three times, each time for 1.5 hours, combine the extracts, recover the ethanol under reduced pressure and concentrate to a relative density 1.05, filtered while hot, added the filtrate to an equivalent hydrochloric acid solution with a concentration of 5mol / L, hydrolyzed at 80°C for 30 minutes, allowed to cool, filtered, washed the filter residue with water until the washing liquid was neutral, and dried at 70°C. Prepare hawthorn extract;

[0042] (1), get functional red yeast rice, pulverize through 80 mesh sieves, set aside;

[0043] (2), take 218g salad oil, add 6g beeswax, 20g hydrogenated palm oil, heat to dissolve, let cool, add 10g soybean lecithin, stir well, add hawthorn extract...

Embodiment 2

[0044] Embodiment 2 hard capsules

[0045] Hawthorn extract 50g Functional red yeast rice 275g Gypenosides 50g

[0046] The hawthorn extract is prepared by the following method: adding hawthorn to 50% ethanol with a mass concentration 10 times the weight of hawthorn, heating and refluxing for three times, each time for 2 hours, combining the extracts, recovering the ethanol under reduced pressure and concentrating to a relative density 1.1, filter while hot, add the filtrate to an equivalent hydrochloric acid solution with a concentration of 7mol / L, hydrolyze it at 100°C for 30 minutes, let it cool, filter, wash the filter residue with water until the washing liquid is neutral, and then dry it at 90°C. Prepare hawthorn extract;

[0047] (1), get functional red yeast rice, pulverize through 80 mesh sieves, set aside;

[0048] (2) Hawthorn extract, gypenosides powder and 275g of starch were added to the functional red yeast rice powder, mixed evenly, dried, sieved, and packed ...

Embodiment 3

[0049] Example 3 tablet

[0050] Hawthorn extract 80g Functional red yeast rice 300g Gypenosides 80g

[0051] The hawthorn extract is prepared by the following method: adding hawthorn to 70% ethanol with a mass concentration 9 times the weight of hawthorn, heating and refluxing for three times, each time for 1 hour, combining the extracts, recovering the ethanol under reduced pressure and concentrating to a relative density 1.05, filtered while hot, added the filtrate to an equivalent hydrochloric acid solution with a concentration of 6mol / L, hydrolyzed at 90°C for 30 minutes, allowed to cool, filtered, washed the filter residue with water until the washing liquid was neutral, and dried at 80°C. Prepare hawthorn extract;

[0052] (1), get functional red yeast rice, pulverize through 80 mesh sieves, set aside;

[0053] (2), add hawthorn extract, gynosides powder, 93g microcrystalline cellulose, 26g micropowder silica gel, 43.5g stearic acid, 26g lactose to the functional red ...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine preparation with a blood fat reducing effect, which is prepared from traditional Chinese medicines such as hawthorn extract, functional red yeast rice and gypenosides, has the efficacies of reinforcing the spleen to promote digestion, removing dampness to eliminate phlegm and promoting blood circulation by removing blood stasis, and is used for treatment of hyperlipemia as well as auxiliary treatment of coronary heart disease, hyperlipemia, other cardiovascular and cerebrovascular diseases caused by atherosclerosis and hypertension. Proven by experimental results, the traditional Chinese medicine preparation can effectively reduce the contents of total cholesterol (TC), triglyceride (TG) and low density lipoprotein (LDL) in blood, regulates lipid metabolism in blood, reduces the concentration of plasma lipid, has the health care function of reducing blood fat, is safe without side effect, and can be taken for a long time.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation with hypolipidemic effect. Background technique [0002] As people's living standards are getting better and better, many middle-aged and elderly people are now troubled by hyperlipidemia. A large number of research data show that hyperlipidemia is a major risk factor for cardiovascular and cerebrovascular diseases such as coronary heart disease, atherosclerosis, myocardial infarction, angina pectoris, cerebral infarction and peripheral vascular thromboembolic disease, and the incidence of these cardiovascular and cerebrovascular diseases is high , the harm is great, the progress of the disease is dangerous, and its mortality rate accounts for about half of the total human mortality. Hyperlipidemia is also an important risk factor for high blood pressure, impaired glucose tolerance, and diabetes. It can also lead to fatty liver, cirrhosis, cholelithiasis, pancreatitis, fundus hemorrha...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61P3/06
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