Containing phytosterol-curcumin compound self-microemulsion natto sauce and its preparation method

A technology of compound self-microemulsion natto paste and phytosterol, which is applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, can solve the problems of no improvement in natto function, etc., and achieves improved bioavailability, removal of Free radicals, the effect of promoting catabolism

Active Publication Date: 2021-11-05
HEFEI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

They are all just optimizing the natto production process, and have not improved the function of natto

Method used

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  • Containing phytosterol-curcumin compound self-microemulsion natto sauce and its preparation method
  • Containing phytosterol-curcumin compound self-microemulsion natto sauce and its preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0033] The natto sauce containing phytosterol-curcumin compound self-microemulsion proposed by the present invention comprises the following raw materials in parts by weight: 120 parts of soybeans, 5 parts of phytosterol-curcumin compound self-microemulsion, 10 parts of other crops, and Bacillus natto 0.05 parts of flour, 0.5 parts of garlic, 1 part of egg white, 0.8 parts of vinegar, 0.5 parts of onion, 1 part of vegetable oil, 1 part of table salt, 0.5 parts of pepper, 0.5 parts of soy sauce, and 0.4 parts of sugar.

[0034] The phytosterol-curcumin compound self-microemulsion includes 10 parts of oil phase, 30 parts of surfactant, 10 parts of co-surfactant, and 1 part of internal packaging substance, wherein the oil phase is mixed with olive oil and lemon essential oil in a mass ratio of 3:1 , the surfactant is polyoxyethylene hydrogenated castor oil and polyoxyethylene castor oil mixed in a mass ratio of 0.4:1, the co-surfactant is PEG400, and the inner packaging material is ...

Embodiment 2

[0049] The natto sauce containing phytosterol-curcumin compound self-microemulsion proposed by the present invention comprises the following raw materials in parts by weight: 120-180 parts of soybeans, 10 parts of phytosterol-curcumin compound self-microemulsion, 30 parts of other crops, sodium 0.15 parts of soybean powder, 1.5 parts of garlic, 2 parts of egg white, 1.2 parts of vinegar, 1 part of onion, 2 parts of vegetable oil, 2 parts of salt, 1 part of pepper, 1 part of soy sauce, 0.8 parts of sugar.

[0050] The phytosterol-curcumin compound self-microemulsion includes 40 parts of oil phase, 70 parts of surfactant, 25 parts of co-surfactant, and 20 parts of internal packaging substances, wherein the oil phase is mixed with olive oil and lemon essential oil in a mass ratio of 5:1 , the surfactant is polyoxyethylene hydrogenated castor oil and polyoxyethylene castor oil mixed in a mass ratio of 4:1, the co-surfactant is PEG400, and the inner packaging material is phytosterol...

Embodiment 3

[0065] The natto paste containing phytosterol-curcumin compound self-microemulsion proposed by the present invention comprises the following raw materials in parts by weight: 150 parts of soybeans, 8 parts of phytosterol-curcumin compound self-microemulsion, 20 parts of other crops, and Bacillus natto 0.1 part powder, 1 part garlic, 1.5 part egg white, 1 part vinegar, 0.8 part onion, 1.5 part vegetable oil, 1.5 part salt, 0.8 part chili, 0.8 part soy sauce, 0.6 part sugar.

[0066] The phytosterol-curcumin compound self-microemulsion includes 25 parts of oil phase, 50 parts of surfactant, 18 parts of co-surfactant, and 10 parts of internal packaging substances, wherein the oil phase is mixed with olive oil and lemon essential oil in a mass ratio of 4:1 , the surfactant is polyoxyethylene hydrogenated castor oil and polyoxyethylene castor oil mixed in a mass ratio of 2:1, the co-surfactant is PEG400, and the inner packaging material is phytosterol and curcumin mixed in a mass ra...

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Abstract

The invention discloses natto sauce containing phytosterol-curcumin compound self-microemulsion and a preparation method thereof, comprising the following raw materials in parts by weight: 120-180 parts of soybeans, 5-10 parts of phytosterol-curcumin compound self-microemulsion, 10-30 parts of other crops, 0.05-0.15 parts of natto bacteria powder, 0.5-1.5 parts of garlic, 1-2 parts of egg white, 0.8-1.2 parts of vinegar, 0.5-1 part of onion, 1-2 parts of vegetable oil, 1-2 parts of table salt 2 parts, 0.5‑1 part of pepper, 0.5‑1 part of soy sauce, 0.4‑0.8 part of sugar. The particle size of the phytosterol-curcumin compound self-microemulsion obtained in the present invention is less than 60nm, the drug loading of phytosterol is higher than 8.26mg / g, the drug loading of curcumin is higher than 0.64mg / g, and the encapsulation efficiency is higher than 90%. Phytosterols and curcumin have different blood lipid-lowering mechanisms, and the two complement each other to achieve a synergistic blood-fat-lowering effect; in the present invention, compounding these several natural non-toxic substances with obvious blood-fat-lowering functionality can play a good role To prevent and alleviate cardiovascular diseases headed by hyperlipidemia, it has a good health care effect.

Description

technical field [0001] The invention relates to the technical field of functional food, in particular to a compound self-microemulsion natto sauce containing phytosterol-curcumin and a preparation method thereof. Background technique [0002] According to statistics from the World Health Organization, cardiovascular disease ranks first in the global ranking of death factors, even surpassing the lethality of cancer to humans. Data point out that in the global death toll, the number of deaths caused by cardiovascular diseases accounts for 50% of the total human deaths, and hyperlipidemia is one of the main causes of human cardiovascular diseases. Hyperlipidemia is a vascular disease caused by lipid metabolism disorder in serum, which manifests as elevated serum triglyceride (TG), total cholesterol (TC) and low-density lipoprotein (LDL-C), while high-density lipoprotein (HDL-C) decreased. Studies have shown that hyperlipidemia can lead to atherosclerosis and induce coronary h...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/00A23L11/00A23L33/11A23L33/105A61K31/575A61K31/12A61P3/06A23L11/50A23L11/70
CPCA61P3/06A23L33/00A23L33/105A23L33/11A61K31/12A61K31/575A23V2002/00A23L11/50A23V2200/326A23V2250/2136A23V2250/2112A61K2300/00
Inventor 袁传勋张雪茹金日生徐云郭玉华
Owner HEFEI UNIV OF TECH
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