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35 results about "Bean extract" patented technology

Composition for caring for and / or making up keratin materials

A composition, preferably for caring for and / or making up keratin materials, comprising: a) a giant knotweed glycoside and / or a derivative thereof, and b) a Lens culinaris extract.
Owner:LOREAL SA

Process for separating pinitol from carob extract

ActiveJP7812414B2Chromatographic cation exchangersOrganic compound preparationBiotechnologyPinitol
To provide a process for the separation of at least one inositol from a carob extract.SOLUTION: This process comprises the steps of: a) providing a filtered and demineralised carob extract having a Brix value greater than 60 and a pinitol content, in weight percent based on the weight of the extract, from 5 to 25%; b) subjecting the carob extract of step a) to a process of chromatographic separation of the pinitol, wherein the process comprises subjecting the extract to at least one passage through a chromatographic resin, thus obtaining an aqueous solution having a pinitol content, in weight percent based on the total weight of the solution, from 35 to 70%, and which has a Brix value of 20 or lower; and c) subjecting the aqueous solution thus obtained in step b) to a purification step, thus obtaining a purified aqueous solution having a pinitol content, in weight percent based on the total weight of the solution, of more than 55%.SELECTED DRAWING: Figure 1
Owner:BONO & DITTA SPA

Coffee bean extract, food and drink, packaged beverage with improved flavor, and method for producing the coffee bean extract

The purpose of the present invention is to provide a coffee bean extract that contains an extract of coffee beans of Liberica species and has an improved flavor with reduced stuffy odor, a method for producing the same, etc. The present invention pertains to an extract of coffee beans wherein the content of isovaleric acid per soluble solids is less than 10 ppm and the coffee beans include coffee beans of Liberica species.
Owner:SUNTORY HLDG LTD

Plant-based compositions and methods of modulating inflammatory response following viral infection

A polyphenol-rich composition is orally taken to alleviate a symptom or symptom of a post-viral infection syndrome, and preferably post-COVID syndrome. Most typically, the composition comprises at least 50 wt% of total catechins, at least 20 wt% of total chlorogenic acids, and optionally up to 30 wt% of total supplemental antioxidants. The composition may be formulated from a green coffee bean extract, a green tea extract, a turmeric extract, sour cherries or an extract thereof, broccoli or an extract thereof, and kale or an extract thereof. It is worthy of notice that such compositions are effective in reducing proinflammatory cytokines and interleukinins, increasing NOHb, and reducing reactive oxygen species caused by mitochondrial dysfunction, iNOS activity, and NOX2 activity in individuals infected with SARS-CoV2.
Owner:VDF FUTURECEUTICALS INC

Compound preparation for inhibiting aspergillus flavus and application of compound preparation in prevention and treatment of aspergillus flavus pollution

PendingCN121264492ABiocideEdible seed preservationBiotechnologyWinged beans
The invention provides a compound preparation for inhibiting aspergillus flavus and application of the compound preparation in prevention and treatment of aspergillus flavus pollution, and the compound preparation comprises a compound microbial agent and a compound extract preparation, the compound microbial agent is prepared by mixing the following microbial agents in parts by weight: 5-10 parts of bacillus sorola, 5-10 parts of bacillus amyloliquefaciens and 3-8 parts of black yeast; the composite extract preparation is prepared by mixing a winged bean extract and a vanilla bean extract according to a weight ratio of (30-55): 1. The plant extract and the microbial agent are compounded to inhibit the aspergillus flavus, the antibacterial effect is good, and a new direction is provided for preventing and treating the aspergillus flavus of grain and oil crops and grain products.
Owner:GUANGXI NORMAL UNIV FOR NATITIES

Production method of green coffee bean extract capable of improving alpha-glucosidase inhibitory activity

The invention discloses a production method of a green coffee bean extract capable of improving alpha-glucosidase inhibitory activity. Cellulase and pectinase are used for improving the yield of chlorogenic acid and a derivative (CGAs) of chlorogenic acid, tannase and esterase are used for conducting structural modification on polyphenol and CGAs in green coffee bean extract clear liquid, and then lactobacillus rhamnosus, lactobacillus paracasei and bacillus subtillis form a composite strain for fermentation. According to the method, the proportion of CGAs components and the proportion of caffeic acid in the green coffee bean extract are improved by combining an enzymic method with the probiotics to ferment the green coffee bean extract, and the alpha-glucosidase inhibitory activity of CGAs and metabolites thereof is improved.
Owner:BEIJING GERSON XINGU BIOTECHNOLOGY DEVELOPMENT CO LTD

Dermatological composition for external application

The present invention relates to a dermatological composition for external application, containing, as an active ingredient, a complex ingredient comprising betulin, a ceramide, a soybean extract, and a green tea seed extract. The dermatological composition for external application has the effects of improving the skin barrier by activating keratinocyte proliferation, enhancing the moisture retention of the skin by reducing transepidermal water loss, and improving acne by inhibiting the lipase activity of Cutibacterium acnes.
Owner:AE KYUNG IND CO LTD

Method for green synthesis of nano spherical silver powder from black bean and natto extract

The invention belongs to the technical field of nano material preparation, and discloses a method for green synthesis of nano spherical silver powder from black bean and natto extracts, which comprises the following steps: adding a sodium borohydride solution into a first silver nitrate solution, and magnetically stirring to obtain a yellow seed crystal solution; a dispersing agent is added into the second silver nitrate solution, then the pH is adjusted to 3.8-4.2, and a mixed solution A is obtained; adding the mixed solution A into the black bean and natto extract solution, and uniformly mixing to obtain a growth solution; adding the seed crystal solution into the growth solution, and stirring to obtain a mixed solution B; adding a catalyst into the mixed solution B, and carrying out electric field induction, solid-liquid separation and washing to obtain a washing product; and polyhydric alcohol is added into the washing product, then treatment is conducted through magnetic stirring, after magnetic stirring is completed, solid-liquid separation is conducted, a solid product obtained through separation is subjected to vacuum drying, and the nanometer spherical silver powder is obtained. The nanometer spherical silver powder prepared through the method is controllable in particle size, narrow in distribution, high in sphericity degree and high in purity.
Owner:XI'AN UNIVERSITY OF ARCHITECTURE AND TECHNOLOGY +1

Insecticidal preparation based on rosemary-mint mixed oil as well as preparation method and application

The invention discloses an insecticidal preparation based on rosemary-mint mixed oil and a preparation method and application thereof, and belongs to the crossing field of green agriculture and biotechnology. The mixed essential oil is efficiently extracted through an ultrasonic-subcritical coupling extraction process, the rosemary oil extraction rate can reach 12.1%-12.4%, the menthol retention rate reaches 95.2%-97.1%, and the solvent residue is lower than 0.01 mg / kg; a full-plant-source ternary compound system (mixed essential oil, sophora alopecuroide extract and citrus peel oil) is designed, the synergistic coefficients of 50 formulas are all larger than or equal to 1.25, and six types of pests including thrips, red spiders, aphids, whiteflies, plutella xylostella and leafhoppers can be covered; a special application technology for eight types of crops (including tea leaves and traditional Chinese medicinal materials) is established, the quality of the crops reaches the standard after pesticide application, for example, the water extract of the tea leaves is increased by 1.2%, and the astragaloside content meets the standard of Chinese Pharmacopoeia 2020 edition; the storage stability is optimized, the control effect retention rate can reach 94.7% after 6 months of normal-temperature storage, and the requirement of 2-year industrial shelf life can be met; finally, the average reduction rate of the chemical pesticide is 90.3%, and the preparation cost is less than or equal to 80 yuan / kg. The composition can replace chemical pesticides and is suitable for green prevention and control of insect pests of fruits and vegetables, fields, commercial crops and traditional Chinese medicinal materials.
Owner:一毫米生物科技(杭州)有限公司

Pharmaceutical composition for reducing uric acid and preparation method thereof

The invention provides a pharmaceutical composition for reducing uric acid and a preparation method thereof, and belongs to the technical field of biological pharmacy, and the active ingredients of the pharmaceutical composition comprise an okra seed extract, a carrot leaf extract, a red sword bean extract, quercetin and resveratrol. The abelmoschus esculentus seed extract is prepared by performing compound enzymolysis on abelmoschus esculentus seeds by cellulase, pectinase and xylanase, fermenting the abelmoschus esculentus seeds by rhizopus oryzae to obtain an extracting solution, and purifying the extracting solution by a D101 macroporous adsorption resin column and a polyamide chromatographic column. The carrot leaf extract is a component which is obtained by extracting carrot leaves with an ethanol water solution and is less than 10kDa. The red sword bean extract is prepared by the following steps: degreasing red sword bean seeds, carrying out compound enzymolysis on the degreased red sword bean seeds by using neutral protease and beta-glucosidase, fermenting the degreased red sword bean seeds by using lactobacillus plantarum to obtain an extracting solution, and processing the extracting solution by using a Sephadex G25 gel column. All the components are compatible to construct a multi-component, multi-target and multi-channel action system, and good acid reduction is realized by inhibiting uric acid to generate key enzyme and regulating purine metabolism.
Owner:GUANGDONG ZONOPO INTELLIGENT TECH

A hangover-preventing and liver-protecting composite fermented beverage containing white horse bean extract and a preparation method thereof

The present application belongs to the field of functional fermented drinks, and provides a hangover-alleviating and liver-protecting composite fermented drink containing white lentil extract and a preparation method thereof. The present application forms a grafted core through "covalent grafting of white lentil amino components and D-anhydrous glucose Maillard", constructs a core-shell nanocomposite with tea polyphenols, and realizes high-stable nanodispersion of D50 80-200 nm and PDI≤0.25, high-load interface combination of tea polyphenols 10%-50%, and low-melting easy processing of 20-300 mPa·s and long-term anti-settling and anti-flocculation at pH 3.2-4.6, thereby solving the contradictions of low-melting and high-solid-content stability in an acidic plant-based fermentation system, high-polyphenol loading causing turbidity and astringency, and activity deterioration caused by heat treatment.
Owner:XIANGNAN UNIV

Earthworm protein composition for regulating ovarian function to improve menopausal syndrome and preparation method and application thereof

The present application relates to the technical field of biological medicine, in particular to a diplommatin composition for regulating ovary function and improving menopausal syndrome, a preparation method and application thereof, active ingredients of the composition include diplommatin and cranberry extract by mass fraction, and the mass ratio of diplommatin to cranberry extract is 1:(0.5-5), or active ingredients of the composition are composed of diplommatin, cranberry extract and carob extract according to a mass ratio of 1:(0.5-5):(0.5-5). The composition has a simple component design, effectively solves the problems of "complex components, unknown mechanism, low bioavailability and poor long-term safety" in the prior art through multi-component synergy, and precisely regulates ovary function and systematically improves menopausal syndrome related symptoms.
Owner:HUBEI TANGYUAN BIOMEDICAL TECH CO LTD

Lipid-lowering weight-losing composition and application thereof

The invention relates to the technical field of health-care products, and aims to provide a lipid-lowering and weight-losing composition which comprises the following components in parts by mass: 10-15 parts of chitosan, 20-35 parts of a tea bean extract, 5-10 parts of a pawpaw extract, 2-8 parts of a Chinese wolfberry extract, 2-10 parts of an immature bitter orange extract, 5-10 parts of a nomame senna extract, 2-6 parts of composite biomass and 5-10 parts of dietary fibers. By reasonably selecting various components with different fat-reducing and weight-losing mechanisms, controlling the dosage of the components and scientifically matching the components, the obtained composition has the advantages of good effect and quick response, and does not generate dependence.
Owner:GUANGDONG SUKANG BIOTECHNOLOGY CO LTD

Aerosol type hair mask spray and preparation method thereof

The invention relates to the field of daily chemical products, and particularly discloses an aerosol type hair mask spray which comprises ethanol, propylene glycol, a surfactant, a nourishing component, a repairing component, a hair conditioner, a humectant, a preservative, essence and deionized water. The nourishing component comprises a coconut oil extract, a Morocco nut oil extract, butyrospermum parkii butter and a camellia seed oil extract; the repairing component comprises hydrolyzed keratin, hydrolyzed silk protein, hydrolyzed soybean extract and globe artichoke extract. The invention also discloses a preparation method of the aerosol type hair mask spray. The aerial fog type hair mask spray has the advantages of uniform spray coverage, efficient nutrition absorption and long-acting hair repair, and has the effects of refreshing, convenience and deep hair care.
Owner:广东自由能科技股份有限公司

Preparation process for extracting high-content chlorogenic acid from broken green coffee beans

The present invention relates to a preparation process for extracting high-content chlorogenic acid from broken green coffee beans. In the process, a non-organic solvent method is used, and by means of steps such as raw material pretreatment, low-temperature ultrasonic enzymatic extraction, column chromatography, concentration and spray drying, a low-caffeine green coffee bean extract is obtained, which is enriched with active ingredients such as chlorogenic acid and various caffeoylquinic acid substances. In the preparation process of the present invention, a protective agent is used for preventing the degradation of chlorogenic acid caused by heating and exposure to air, a resin step-gradient separation method is used to enrich chlorogenic acids and remove caffeine, and a UPLC technique is used to achieve the simultaneous quantitative detection of various caffeoylquinic acid components. The preparation process of the present invention has no organic solvent residue, a high content of active ingredients and high separation efficiency, is safe and environmentally friendly, and is suitable for large-scale production. The final product not only contains a high chlorogenic acid content and a low caffeine content, but is also rich in active ingredients such as caffeoylquinic acid substances. Compared to a market-available product, the final product has a superior flavor and less application difficulties in the food and beverage industry.
Owner:ZHEJIANG SKYHERB BIOTECHNOLOGY INC

Topical skin care composition for modulating epidermal gene expression

There is a topical skin care composition composed of a blend of hydroxytyrosol, green coffee extract and green tea leaf extract for use in the modulation of epidermal cellular gene expression profiles to alleviate various skin disorders and significantly reduce the resultant disease symptoms and reduce the rate at which the skin ages. More specifically, the topical skin care composition has hydroxytyrosol at a concentration range of 0.1% w / w to 0.75% w / w, green tea extract at a concentration range of 0.025% w / w to 0.1% w / w; and green coffee bean extract at a concentration range of 0.025% w / w to less than 0.2% w / w. A method of treating one or more of the hallmarks of ageing and skin degradation and collagen and elasticity as a single dosage from a pharmaceutical composition is described, as well as a method of activating skin cells having the step of applying the topical skin composition.
Owner:DERMA RES GRP INC

Traditional Chinese medicine preparation and preparation method thereof

PendingCN121313727AAntipyreticAnalgesicsCentella asiatica extractVigna umbellata
The invention discloses a traditional Chinese medicine preparation which comprises a cotton rose hibiscus leaf extract, a centella asiatica extract, a Japanese cayratia herb extract, a phaseolus calcaratus extract and a lithospermum erythrorhizon extract which are extracted from cotton rose hibiscus leaves, centella asiatica, Japanese cayratia herb, phaseolus calcaratus and lithospermum erythrorhizon as raw materials. The extraction method comprises the following steps: respectively adding 30% ethanol which is 8 times of the mass of the raw materials into the raw materials, refluxing twice, and concentrating at 55-65 DEG C until the specific gravity is 1.10-1.14 to prepare an extract of the raw materials; or adding pure water of which the mass is 10 times that of the raw materials into the raw materials, refluxing twice, and concentrating at 60-80 DEG C until the specific gravity is 1.12-1.16, so as to obtain the extract of the raw materials. Effective components in traditional Chinese medicines are fully extracted, the efficacy of the traditional Chinese medicine preparation is improved, and irritation of the preparation to skin is reduced.
Owner:RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE +1

Weight management composition

The invention provides a method of promoting weight management in a mammal comprising administering to the mammal a composition comprising at least one weight loss agent and at least one mitochondrial enhancer. The weight loss agent can be selected from the group consisting of psyllium, guar gum, capsaicin, chitosan, caffeine, gamboge, mume, capsaicin, yohimbine, butterfly pea, glucomannan, African mango, guarana, pyruvate, carnitine, beta-glucan, fucoxanthin, raspberry ketone, white kidney bean, kola nut, chromium, ginseng, psyllium, St. John's wort, dandelion, hydroxycitric acid, conjugated linoleic acid, green tea, black tea, coffee bean extract, forskolin, and bitter orange. The mitochondrial enhancer can be selected from the group consisting of beetroot extract, nitrate, idebenone, nicotinamide riboside, elamipretide, vitamin C, vitamin D, vitamin E, thiamine, riboflavin, magnesium, calcium, phosphate, phospholipid, creatine, pyruvate, coenzyme Q10, NADH, niacin, L-carnitine, dichloroacetate, curcumin, schisandrin, and resveratrol. Compositions for weight management are also provided.
Owner:ASERKIN CO LTD

A carbon-blocking fat-burning coffee beverage and a method of preparing the same

PendingCN122139838ACoffee extractionBiotechnologyAmylase inhibitors
The present application relates to a kind of carbon fat-burning coffee beverage and its preparation method.The raw materials of the carbon fat-burning coffee beverage include composite coffee liquid, carbohydrate absorption inhibition composite system, fat metabolism promotion composite system, auxiliary material and water, the carbohydrate absorption inhibition composite system includes white kidney bean extract, green coffee bean extract and mulberry leaf extract, the fat metabolism promotion composite system includes medium-chain triglyceride and L-carnitine tartrate.In the carbohydrate absorption inhibition composite system, white kidney bean extract (alpha-amylase inhibitor), mulberry leaf extract (DNJ), green coffee bean extract (chlorogenic acid) are respectively targeted at starch, disaccharide, glucose hydrolysis and absorption link, and form full-link carbon interception;In the fat metabolism promotion composite system, medium-chain triglyceride (MCT) provides energy quickly to reduce fat, L-carnitine tartrate accelerates fatty acid beta-oxidation, and both consume stock fat.
Owner:AOTAI (GUANGDONG) BIOTECHNOLOGY CO LTD

Polygonatum sibiricum beverage and preparation method thereof

The invention relates to a rhizoma polygonati beverage and a preparation method thereof. Every 500ml of the rhizoma polygonati beverage contains 4-6.36% of rhizoma polygonati extract, 5-8% of fruit extract, 1-3% of bean extract, 1-1.64% of traditional Chinese medicinal material extract, 2% of honey and the balance of purified water. A rhizoma polygonati extract, a traditional Chinese medicinal material extract, a bean extract and a fruit extract which are used for relieving summer heat and relieving fatigue are further prepared in a basic formula of the rhizoma polygonati beverage, and the rhizoma polygonati beverage is nutritional soup for tonifying summer heat and relieving fatigue and has the effects of tonifying qi, clearing heat, driving away summer heat, promoting salivation and relieving summer heat by mixing the extract raw materials, so that the effects of improving the body immunity, relieving fatigue and the like are achieved. The health-care tea has the effects of refreshing, relieving fatigue, promoting salivation, quenching thirst, improving eyesight, maintaining mental tranquility and tonifying qi, can improve the poor state of the body and relieve fatigue and tuberculosis of the body, and has the effects of resisting oxidation, improving memory and relieving qi deficiency.
Owner:HUBEI MENGDA TECHNOLOGY IND CO LTD

Application of pigeonpea extract and active ingredients in relieving hyperuricemia

The invention provides application of pigeon pea extract and active ingredients in preparation of drugs or functional food for relieving hyperuricemia. Animal experiment research finds that intervention of pigeon pea extract and pinostrobin significantly reduces serum uric acid content of a hyperuricemia mouse, prevents serum creatinine and / or serum urea nitrogen in vivo from increasing, and can increase urine urea nitrogen and / or urine creatinine excretion; meanwhile, the pigeonpea extract and the pinostrobin can restore the kidney and liver coefficients of a hyperuricemia mouse to a normal level, remarkably relieve kidney injury caused by hyperuricemia, inhibit kidney inflammation / fibrosis reaction and restore the physiological state of the kidney to the level of a normal mouse.
Owner:SOUTH CHINA BOTANICAL GARDEN CHINESE ACADEMY OF SCI

Application of galega orientalis extract in preparation of feed additive for improving poultry meat quality

The invention provides application of a galega orientalis extract in preparation of a feed additive for improving poultry meat quality, and belongs to the field of feed additives. The capsella orientalis extract is obtained by extracting with a 50% ethanol aqueous solution and purifying with macroporous resin. The feed is used for improving the breast muscle quality, meat color, meat quality and physical and chemical quality of meat chickens. Moreover, the galega orientalis extract can promote the growth of beneficial bacteria by adjusting poultry intestinal microbiota, so that the galega orientalis extract is remarkably associated with poultry meat quality indexes.
Owner:INSTITUTE OF ANIMAL SCIENCES OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES

Method for improving antioxidant activity of green coffee bean extract and small intestine absorption amount of polyphenols

The invention discloses a method for improving the antioxidant activity of a green coffee bean extract and the small intestine absorption amount of polyphenols. The preparation method comprises the following steps: performing enzymolysis to obtain a green coffee bean extract clear liquid, performing enzymolysis on a clear liquid combination esterase and lactic acid bacteria group combination (lactobacillus rhamnosus, lactobacillus paracasei, lactobacillus crispatus and lactic acid bacteria Lcasei-01), and then performing fermentation; the green coffee bean extract is subjected to enzymatic modification and microorganism synergistic fermentation to replace small intestine enzymolysis and large intestine lactic acid bacteria groups to decompose polyphenol, and the difference of the intestinal lactic acid bacteria groups of different people is eliminated through modernized fermentation of probiotic groups in a fermentation tank; according to the present invention, the standard enzymolysis and the fermentation of the polyphenol and the chlorogenic acid in the green coffee bean extract are achieved, the restriction structure modification of the chlorogenic acid in the green coffee bean extract is achieved under the determined fermentation condition, and the content of the polyphenol and the total chlorogenic acid derivative in the green coffee bean extract is significantly improved; and when the ratio of chlorogenic acid 5-CQA: 3-CQA: 4-CAQ: caffeic acid is determined, the antioxidant activity of the fermented green coffee extract is improved by 1.2 times or more, and the small intestine absorption amount of polyphenol active substances is improved by 2 times or more.
Owner:CHINA AGRI UNIV +1

GABA-polypeptide composite nerve-soothing and wrinkle-removing composition, application thereof and nerve-soothing and wrinkle-removing skin care product

PendingCN121533933ACosmetic preparationsToilet preparationsType XVII collagenCollagenan
The invention relates to a GABA (gamma-aminobutyric acid)-polypeptide composite nerve soothing and wrinkle removing composition and application thereof as well as a nerve soothing and wrinkle removing skin care product. The composition is prepared from gamma-aminobutyric acid, tephrosia purpurea extract and recombinant XVII type collagen in a mass ratio of (0.1-2): (0.1-1.5): (0.1-1.5). Compared with the prior art, a single-dimensional anti-aging mode is broken through, a skin conditioning system with gamma-aminobutyric acid, tephrosia purpurea Seed Extract and recombinant XVII type collagen as main components is constructed, and the components are cooperatively used to form a three-level skin state improvement path of nerve regulation, barrier repair and basement membrane regeneration.
Owner:SHANGHAI MCGILL DAILY NECESSITIES CO LTD

Agent for improving rough skin before menstruation

To provide a Chinese herbal medicine that can improve rough skin before menstruation.SOLUTION: Keishi-bukuryo-gan-ka-yokuinin extract and / or unkei-to extract has a great effect of improving rough skin before menses, so that it can be used as an active ingredient in an agent for improving rough skin before menstruation.SELECTED DRAWING: None
Owner:KOBAYASHI PHARMA CO LTD

Method for producing basil tomato chicken breast bar using vegetable protein materials

PendingKR1020260112884ABiotechnologyPeanut meal
The present invention relates to a method for manufacturing a basil tomato chicken breast bar and a basil tomato chicken breast bar manufactured by the said method, characterized by comprising the steps of: preparing a chicken breast mixture by mixing plant tissue protein hydrate, chicken breast, salt, sugar, L-sodium glutamate, isolated soy protein, wheat gluten, hemp seed meal powder, defatted peanut powder, black soybean powder, corn starch, modified starch, maltodextrin, meat flavor seasoning, ham flavor, basil tomato sauce, pea extract mixture, transglutaminase, hemp seed oil, and water; filling a casing with the prepared chicken breast mixture, heat treating, and cooling; and inserting a stick into the cooled chicken breast mixture.
Owner:HERS DELI CO LTD +1

Soybean paste and method for preparing the same

ActiveCN115381034BProcess engineeringBean extract
The present application relates to the brewing technology field of fermentation products, in particular to a bean sauce and a preparation method thereof. The preparation method of the bean sauce comprises a step of modulating a half-finished product of sauce mash, and the modulating process comprises a step of adding soybean extract. The present application can solve the problem of gas swelling of the bean sauce during the shelf life.
Owner:FOSHAN HAITIAN GAOMING FLAVORING & FOOD +3

Application of tobacco bean extract in preparation of anti-inflammatory and analgesic external medicine

The invention provides an application of a tobacco bean extract in preparation of an anti-inflammatory and analgesic external medicine, and in a chronic / acute inflammation model, the tobacco bean extract can effectively relieve mouse atopic dermatitis / ear inflammation symptoms induced by dinitrochlorobenzene (DNCB) / xylene; in the aspect of analgesic effect, the tobacco bean extract can relieve mouse pain response caused by hot plate stimulation and prolong the pain threshold latency period; mechanism research shows that the tobacco bean extract can significantly inhibit expression of various inflammation-related cytokines; therefore, the tobacco bean extract can obviously improve various acute and chronic inflammations, can relieve nerves, and has the potential of treating inflammations and inflammatory pain. Besides, the safety evaluation result shows that no obvious toxic reaction is caused in the experimental dose range, the toxicity burden caused by the inducer can be reduced in a disease model, and the safety and the application prospect are good.
Owner:UNIV OF MACAU