Sunflower head extract prepared by crystallization enzymolysis method and preparation method of sunflower head extract

A technology of sunflower disc and extract, which is applied in the field of sunflower disc extract and its preparation, and preparation of medicines for the prevention and treatment of gout, which can solve the problems of resource waste and achieve low production cost, lower uric acid and high extraction efficiency

Active Publication Date: 2016-08-24
洮南市金塔生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In order to overcome the current situation of resource waste in this technical field and develop more safe and effective sunflower disc active ingredients, the invention provides a sunflower disc extract, which is rich in total flavonoids, small molecular peptides and alkaloids, and has the ability to reduce Blood uric acid, eliminate the pain caused by gout, dissolve tophi, anti-inflammation and swelling effect, has a significant effect on the prevention and treatment of gout, and has less toxic and side effects, and can be taken for a long time

Method used

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  • Sunflower head extract prepared by crystallization enzymolysis method and preparation method of sunflower head extract
  • Sunflower head extract prepared by crystallization enzymolysis method and preparation method of sunflower head extract
  • Sunflower head extract prepared by crystallization enzymolysis method and preparation method of sunflower head extract

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Embodiment 1

[0026] The preparation method of the sunflower disc extract: Weigh 10kg of fresh or frozen seedless sunflower disc, crush the sunflower disc into 80 mesh fine powder, add 5 times the mass of 20% ethanol solution, and place it in a flash crushing extractor (Heze Jiepu Instrument Co., Ltd.), the extraction time is 100s, the extraction voltage is 150V, and then the suspension crystallization method is used for low-temperature freezing and concentration. (mass ratio 1:2 mixed) enzymatic hydrolysis for 3 hours, and ultrafiltration with a hollow fiber membrane, the filtrate was frozen and crystallized and concentrated, 0.5kg of glucose was added, spray-dried, sub-packaged, and packaged.

Embodiment 2

[0028]The preparation method of the sunflower disc extract: Weigh 20kg of fresh or frozen seedless sunflower discs, crush the sunflower discs into 100 mesh fine powder, add 8 times the mass of 20% ethanol solution, and place it in a flash crushing extractor (Heze Jiepu Instrument Co., Ltd.) crushing extraction, extraction time 200s, extraction voltage 100V, and then use the suspension crystallization method for low-temperature freezing and concentration, the low-temperature freezing temperature is -40°C, and the concentrated solution is added with 0.003 mass times of compound protease (pepsin and trypsin in mass ratio 1:1.5 mixture) enzymatic hydrolysis, enzymatic hydrolysis for 4 hours, and ultrafiltration with a hollow fiber membrane, the filtrate was frozen and crystallized and concentrated, 1kg of galactose was added, spray-dried, subpackaged, and packaged.

Embodiment 3

[0030] The preparation method of sunflower disc extract: Weigh 30kg of fresh or frozen seedless sunflower disc, crush the sunflower disc into 150 mesh fine powder, add 10 times the mass of 20% ethanol solution, and place it in a flash crushing extractor (Heze Jiepu Instrument Co., Ltd.) crushing extraction, extraction time 300s, extraction voltage 200V, and then use the suspension crystallization method for low-temperature freezing and concentration, the low-temperature freezing temperature is -30°C, and the concentrated solution is added with 0.0048 mass times of compound protease (pepsin and trypsin in mass ratio 1:2.8 mix) enzymatic hydrolysis, enzymatic hydrolysis for 5 hours, and ultrafiltration with hollow fiber membrane, the filtrate was frozen and crystallized and concentrated, added 0.5kg of microcrystalline cellulose, spray-dried, subpackaged, and packaged.

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Abstract

The invention provides sunflower head extract prepared by a crystallization enzymolysis method and a preparation method of the sunflower head extract. A sunflower head is a pure natural traditional Chinese medicine or a material both used as medicine and food; the sunflower head is scientifically extracted to prepare a functional health product both used as medicine and food, which has the effects of resisting gout, treating hyperuricemia, improving the immunity, lowering blood glucose and blood lipid, protecting kidney and liver, eliminating swelling, resisting inflammation and relieving pain and has the effects of dissolving uric acid calculus, lowering serum uric acid concentration, eliminating swelling and resisting inflammation, adjusting purine and uric acid metabolism, balancing in-vivo acid-base equilibrium and balancing in-vivo hormones; the product is safe, has no side effect, has remarkable health effect and can be eaten for a long period, so that a market development prospect is very good.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a sunflower disc extract prepared by a suspension crystallization method and an enzymatic hydrolysis method, a preparation method thereof, and an application for preparing a medicine for preventing and treating gout. Background technique [0002] Gout is a metabolic disease caused by purine metabolism disorder. The blood uric acid concentration rises, and sodium urate crystals are deposited in the bone joints, arteries, and vertebral spaces of the lower limbs. , severe cases showed joint deformity and dysfunction, and has the characteristics of recurrent attacks. The existence of gout can also lead to the exacerbation of coronary heart disease, diabetes, hypertension and other diseases. In terms of treatment, there is no radical cure for gout with Western medicine. Although colchicine, non-steroidal anti-inflammatory drugs, and allopurinol can relieve symp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61P19/06A61K133/00
CPCA61K36/28A61K2236/19A61K2236/333A61K2236/53
Inventor 不公告发明人
Owner 洮南市金塔生物科技有限公司
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