WuRenChun self-emulsifying soft capsule preparation and preparation method
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology of self-emulsifying soft capsules and pentalinol, which is applied in the field of medicine to improve water solubility and bioavailability and reduce serum alanine aminotransferase
Active Publication Date: 2011-11-02
HARBIN MEDICAL UNIVERSITY
View PDF0 Cites 0 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
In recent years, there are three kinds of patents applied for Wurenchun preparations, Wurenchun dripping pills and its preparation method, Wurenchun soft capsule preparations and compound Wurenchun soft capsule preparations. Literature reports and patent applications
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
[0067] The raw material drug of pentarenol was purchased from Xi'an Xiaocao Plant Technology Co., Ltd.; the oil phase, surfactant and co-surfactant are all commercially available products.
[0068] (1) Weigh the oil phase, surfactant, and co-surfactant according to the formula, and mix thoroughly by ultrasonic at 25°C, then add the prescribed amount of pentene alcohol raw material, and mix completely by ultrasonic within 40°C until the drug is completely Dissolve, and the obtained medicine is pressed int...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Property
Measurement
Unit
particle diameter
aaaaa
aaaaa
particle diameter
aaaaa
aaaaa
Login to view more
Abstract
The invention relates to a WuRenChun self-emulsifying soft capsule preparation and a preparation method; WuRenChun (Shizandra ethanol extract containing 2-5% (W / W) of Schizandrol A and 1-3% (W / W) of Schizandrin B) is used for preparing the self-emulsifying soft capsule for curing acute, chronic and metastatic hepatitis, and reducing serum glutamic pyruvic transminase. The WuRenChun self-emulsifying soft capsule preparation comprises: WuRenChun, oil phase, surfactant and auxiliary surfactant, and the component proportion is 1:0.25-3.25:1.5-3.5:2.5-1.25. The preparation method is : the oil phase, the surfactant and the auxiliary surfactant are mixed evenly, the WuRenChun bulk drug is added to be mixed fully with intravascular ultrasound at 40 DEG C until the drug is fully dissolved, the obtained content is pressed into soft capsules according to the conventional method. The invention can enhance the dissolution degree of the WuRenChun, improve the bioavailability and then improve the healing effect.
Description
technical field [0001] The invention belongs to the technical field of medicine, and relates to a pentarenol self-emulsifying soft capsule preparation and a preparation method. Background technique [0002] The traditional Chinese medicine Schisandrae chinensis (Fructus schisandrae chinensis) is the dry ripe fruit of Magnoliaceae plant Schisandrae chinensis (Turcz) Baill. In my country, the schisandra produced in the provinces north of the Yangtze River is called northern schisandra, and the schisandra produced in the south of the Yangtze River, mainly in Zhejiang and Fujian, is called southern schisandra. The quality of northern schisandra is better than that of southern schisandra, and our province is the main producing area of northern schisandra. Wurenol is the alcohol extract of Schisandra chinensis, which has the function of nourishing the liver and kidney. It is used for acute, chronic, and persistent hepatitis. Commercially available Wurenchun single and compound...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more