1146 results about "Lower activity" patented technology

The invention relates to a buffer solution for suspending animal or human cells and for dissolving biologically active molecules in order to introduce said biologically active molecules into the cells using an electric current and to a method for introducing biologically active molecules into animal or human cells using an electric current and a buffer solution. The inventive buffer solution has a buffering capacity of at least 20 mmol*I⁻¹*pH⁻¹ and an ionic strength of at least 200 mmol*I⁻¹ during a change to the pH value from pH 7 to pH 8 and at a temperature of 25° C. The use of a buffer solution of this type in the corresponding method allows biologically active molecules to be introduced into animal and human cells with a high degree of transfection efficiency and at the same time a low cell mortality. Different cell types, in particular dormant and actively dividing cells of low activity, can be successfully transfected in said buffer solution.

This disclosure relates in general to methods and systems for measuring multiphase flows in a pipeline using a combination of venturi, microwave and radiation techniques, where the pipeline is configured to transport hydrocarbons. More specifically, but not by way of limitation, certain embodiments of the present invention provide methods and systems in which low activity radiation sources may be used in combination with one or more microwave transmitter-receiver pairs and pressure differential sensors to measure the flow rates and fractions of phases in multiphase flows in a pipeline, such as may be encountered in producing hydrocarbon wells. Additionally, other embodiments of the present invention provide for the arrangement of one or more microwave transmitter-receiver pairs, one or more radiation source-detector pairs and/or one or more pressure sensor ports in the same cross-section of the throat of a venturi to measure multiphase flow in a hydrocarbon transporting pipeline.

The invention creatively discloses a plate mop and mop bucket. The plate mop and mop bucket comprises a plate mop and a mop bucket (2); the lower side of a mop rod (1) is movably connected with a flat mop plate (11); the flat mop plate (11) is provided with mop cloth; the mop bucket (2) is provided with a water squeezing cavity (3) and a cleaning cavity (8) which are mutually separated from each other; the water squeezing cavity (3) is provided with a water squeezing device; the cleaning cavity (8) is internally provided with a cleaning device; during water squeezing, the flat mop plate (11) rotates to a position parallel to the mop rod (1), is mutually positioned to the mop rod (1) and moves up and down relative to the water squeezing device to wring the mop cloth to squeeze water; and a cleaning component used for cleaning the mop cloth is arranged in the cleaning device, and during cleaning, a part of the cleaning component is placed in water, the flat mop plate (11) rotates to the position parallel to the mop rod (1), is mutually positioned to the mop rod (1) and washes the mop cloth through mutual friction between the cleaning component and the mop cloth in the water. After adopting the structure, the plate mop and mop bucket has the advantages of simple and reasonable structure, convenience to operate and use, capability of alternatively carrying out cleaning and dewatering, saving labor by being cleaned in the water with rapid speed, good water squeezing and cleaning effects and the like.

The present invention provides antibodies and antigen-binding fragments thereof that specifically bind proprotein convertase subtilisin/kexin-9 (PCSK9) with greater affinity at neutral pH than at acidic pH. The antibodies of the invention may possess one or more amino acid changes as compared to antibodies that do not exhibit pH-dependent binding properties. For example, the present invention includes anti-PCSK9 antibodies which possess one or more histidine substitutions in one or more complementarity determining regions. The antibodies of the invention, with pH-dependent binding properties, remain in circulation and exhibit cholesterol lowering activity for prolonged periods of time in animal subjects as compared to anti-PCSK9 antibodies that do not exhibit pH-dependent binding properties. The antibodies of the invention are therefore useful for treating diseases and disorders related to elevated HDL cholesterol, wherein the antibodies of the invention can be administered to a patient at a lower dose and/or with less frequent dosing as compared to antibodies that do not exhibit pH-dependent binding properties.

The invention relates to a catalyst for ethanediol production by oxalic ester hydrogenation, which solves the problems of small specific surface, low activity and poor stability of the catalyst in the previous technique. The catalyst used in the invention is composed of the following active components, assistants and carriers in terms of parts by weight: (a) 5-80 parts of active components; (b) 0-40 parts of assistants and (c) 1-30 parts of carriers, wherein the active component is copper, copper oxide or mixture thereof, the assistant is selected from at least one of Zn, Mn, Ba, Cr, Ni or Fe or oxides thereof and the carrier is selected from at least one of the alumina, silica, zirconia or molecular sieve. When the active component is copper, the technical scheme that the value of (b) is more than zero solves the problem in a good way. The catalyst can be used for ethanediol production in the industry.

The invention discloses an oxide dispersion strengthened low-activation martensitic steel. A substrate is a CLAM steel and contains 0.2 to 0.5 percent of Y2O3 and 0.10 to 0.50 percent of Ti. The method comprises the following steps that: CLAM steel powder, Y2O3 powder and Ti powder are evenly mixed and put in a sealed container for degassing, subjected to mechanical alloying, hot isostatic pressing or hot-pressing sintering and densification molding under the protection of high-purity argon gas, then subjected to hot squeezing or forging and rolling and other machining and molding processes, and the needed section material is prepared; and finally, the section material is subjected to the treatment of quenching and tempering to prepare the oxide dispersion strengthened low-activation martensitic steel ODS-CLAM. The oxide dispersion strengthened low-activation martensitic steel has the advantages that: the low-activation martensitic steel realizes a martensite-based alloy with oxide strengthening phases evenly dispersed and distributed and crystal grains of a reasonable size, can be used as a structural steel material, has the characteristics of strong neutron irradiation resistance, good high-temperature performance, low activation, etc. and is suitable for a fusion reactor and other environments with strong neutron irradiation and high-temperature.

Method and apparatus for real-time tracking of a target in a human body. In one embodiment of the invention, positron emission marker may be implanted into a target, the positron emission marker having a low activity positron isotope. In one embodiment, annihilation gamma rays associated with the low activity positron isotope may be detected using a plurality of position-sensitive detectors. In another embodiment, the target may be tracked in real-time based on a position of the positron emission marker.

A system and method are provided for optimizing maintenance of a geographically distributed data processing system. The method comprises selecting a primary territory having associated operating hours, identifying maintenance hours that exclude the operating hours, and selecting a maintenance time within the available maintenance hours. The midpoint of the maintenance hours may be selected as the maintenance time, or activity distribution data may be analyzed to select a maintenance time corresponding to a low activity time.

A process for reassignment of agents based on their performance in the last performance interval; if the performance of an agent is superior, then he/she is moved to a higher campaign. "Higher" refers to a campaign for which the call center receives a greater remuneration whether or not the call center in turn increases the rate of pay of the agent. Similarly, if the performance is inferior, then the agent is moved to a lower campaign, i.e., one for which the call center receives less remuneration. If the performance just meets the objective, then the agent's assignment stays the same. There can be many levels of superior or inferior performance but the basic principle remains the same.

A pharmaceutical composition is provided that has a low toxicity, demonstrates superior physicochemical properties and pharmacokinetics, and has superior peripheral blood lymphocyte count lowering activity. The pharmaceutical composition contains a compound having general formula (I):

[Chemical Formula 1]

(wherein R¹ represents a methyl group or an ethyl group, R² represents a methyl group or an ethyl group, and R³ represents a phenyl group substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a cycloalkyl group, a lower alkoxy group, a halogeno lower alkyl group, a lower aliphatic acyl group and a cyano group), a pharmacologically acceptable salt thereof or a pharmacologically acceptable ester thereof.

The invention relates to a video quality automatic evaluation method and an evaluation method, relating to the evaluation of wireless video communication, which can confirm the evaluation property, reduce needed reference data and reduce calculation complexity, therefore, the evaluation mode is adaptive to the evaluation application facing wireless network. The method comprises: processing content pre-check on the reference video not compressed; according to the average activity of each activity region, dividing the check on the video characters into high and low activity region character checks, to attain the check parameters representing the spatial domain and time domain characters which express the characters of the video sections in each activity region; weighting the check parameters of the spatial domain and time domain characters of each activity region to build the spatial domain and time domain character parameters of the whole video, realizing the projection between the check parameters and the subjective quality expression according to a preset video quality evaluation database, to realize the automatic evaluation on the video quality facing wireless network.

A method for synthesizing propylene glycol methyl ether relates to a method for synthesizing propylene glycol methyl ether. The method of the invention settles the problems of high reaction temperature, high pressure, low activity of catalyst and low selectivity existing in the prior method for preparing propylene glycol methyl ether. The method comprises the following steps: 1. preparing a compound A; 2. preparing a compound B; and 3. after naturally cooling the mixed solution B to a room temperature, atmospherically distilling and obtaining the propylene glycol methyl ether. The method of the invention has the advantages of simple process, applicable whole reaction in the condition of normal pressure and low-temperature, 93.3%-94.2% of epoxy propane conversion rate, 98.1%-99.1% of product selectivity, and no environment pollution as the whole reaction process is executed under the condition of no dissolvent. The propylene glycol methyl ether (1-methoxy-2-propanol or 2-methoxy-1-propanol) synthesized according to the invention can be synthesized by regulating the mixed liquid of acetate methyl glyoxaline hydroxide or acetate methyl glyoxaline chloride and ferric trichloride.

The invention provides a carbon-loaded kernel-shell copper-palladium-platinum catalyst for a fuel battery and a preparation method thereof. Conductive carbon black is used as a carrier, an active component is a copper-palladium-platinum alloy with a nuclear-shell structure, wherein the copper palladium is a kernel, the platinum is a shell, and the catalyst comprises the following ingredients by mass percent: 70 to 91 percent of conductive carbon black, 2 to 10 percent of copper, 2 to 10 percent of palladium and 5 to 10 percent of platinum. A two-step reduction method is utilized, namely, low-activity metal is firstly reduced, then the active precious metal is reduced, the precious metal is precipitated on the surface of the non-precious metal by controlling the reaction temperature and the pH value, and a kernel-shell catalyst is formed through a dealloying step; and in addition, the carbon carrier is added in the preparation process, so that the nano metal particles can directly grow on the carrier, the combination of the catalyst particles and the carbon carrier can be enhanced, and the catalyst is more stable. Due to the adoption of the preparation method, the catalyzing efficiency of the catalyst and the utilization rate of the precious metal can be greatly improved, and the development of the fuel battery can be promoted.

The invention relates to a bimetal or multi-metal high-dispersion composite coal tar hydrogenation catalyst and a preparation method thereof. The catalyst comprises molecular high-activity components of one or a plurality of mixtures of water-solubility salt compounds of metal from molybdenum, nickel, tungsten or cobalt, nanometer low-activity components gamma-FeOOH grains and micro or sub nanometer carrier pulverized coal, the activity components are uniformly and highly dispersed on the surfaces of the carrier pulverized coal, the catalyst is micro or sub nanometer fine powder and is high in activity, particles of the activity components are small and are highly uniformly dispersed on the surface of a carrier, the utilization quantity of the catalyst is low, cost is reduced, and the bimetal or multi-metal high-dispersion composite coal tar hydrogenation catalyst can be widely applied to coal tar hydrogenation or coal liquefaction.

In order to maintain the surface area of an alumina catalyst over the course of operation and regeneration, a method of incorporating phosphorus into the alumina has been developed. By incorporating a small amount of phosphorus, the resulting catalyst is better able to withstand hydrothermal conditions, such as during a carbon burn step, which causes alumina surface area to degrade or decrease. Reduced surface area also desorbs chloride from the catalyst, lowering activity and increasing corrosion. Here, steam treatments have been used to simulate commercial hydrothermal stability and a critically small amount of phosphorus has been discovered which balances an increased surface area against decreased chloride retention. Increased surface area results from increased phosphorus, yet higher levels of phosphorus blocks ability to hold chloride. Moreover, X-ray data shows that an amount as low as 0.2 wt-% phosphorus increases alumina transition temperature, while pilot plant data shows excellent naphtha reforming yields.

The invention relates to a method for converting heavy aromatics to light aromatics and transferring an alkyl radical, which mainly solves the problem of low activity during the reaction of converting the heavy aromatics to the light aromatics and transferring the alkyl radical in the presence of a conventional catalyst. In the invention, a new method for converting the heavy aromatics to the light aromatics and transferring the alkyl radical is adopted, wherein the catalyst comprises the following components in part by weight: a) 5 to 95 parts of nuclear-shell molecular sieve material and b)95 to 5 parts of adhesive; the nuclear phase of the nuclear-shell molecular sieve is ZSM-5; and the shell layer is beta zeolite grains with coverage of between 50 and 100 percent. The technical scheme solves the problem better and the method can be used in the industrial production of converting the heavy aromatics to the light aromatics and transferring the alkyl radical.

A power supply and method for a central processing unit (CPU). The power can include a first power supply circuit such as a DC/DC converter for supplying a voltage of a first level to the CPU when the CPU is in a high activity mode, and a second power supply circuit such as an LDO regulator circuit for supplying a voltage of a second level lower than the first level to the CPU when the CPU is in a low activity mode. The second power supply circuit is preferably efficient when the CPU is in a low load or low activity mode. In such a power supply, when the CPU is in the low activity mode, the LDO regulator circuit is operated to reduce or prevent the efficiency from being degraded, reduce a CPU power consumption and extend a CPU battery lifetime.

The invention relates to a catalyst for dehydrogenating light alkane in order to mainly solve the problem of relatively-low activity of a dehydrogenating catalyst prepared in the prior art. The problem is better solved through the technical scheme that the catalyst for dehydrogenating light alkane comprises the following components in parts by weight: 1-30 parts of a Cr element or an oxide of the Cr element (a), 0.1-5 parts of alkali metal oxides or alkaline earth metal oxides (b), 0.001-1 part of the group VA elements selected from a periodic table of elements or oxides of the group VA elements (c), 0.001-1 part of the group IIIA elements selected from the periodic table of elements or oxides of the group IIIA elements (d), and 54-99 parts of Al2O3 or SiO2 (e). The catalyst can be used for industrial production of light olefin prepared by dehydrogenating light alkane.

The invention provides a method for preparing separated soy protein and comprises the following steps: (1) the preparation of concentrated soybean albumen powder by vacuum drying alcoholic method; (2) solution preparation and heat treatment; (3) acid coprecipitate and neutrality adjustment; (4) instantaneous heating and sterilizing as well as sponging drying. The separated soy protein prepared by the method not only has the advantages of high solubility and high protein content of common protein isolate, but also has the advantages of low beanyflavor, light color, low activity of nutrition resistant substance, easy treatment on discharged sewage, and the like which are not possessed by common separated soy protein; therefore, the invention is an ideal preparation method for producing beverage type separated soy protein.