The invention belongs to the technical field of
isotope production, and particularly relates to a 177Lu
irradiation production method based on a
pressurized water reactor. Comprising the following steps: step 1, packaging Lu2O3
powder in a target box, performing sealing treatment, and storing the target box in a
storage tank of a rabbit
system outside a reactor core; 2, during the operation period of the
pressurized water reactor, transporting the target piece box into the reactor core through a running rabbit
system; 3, the target piece box receives
neutron irradiation at the axial middle position of the central instrument
pipe, and 176Lu reacts to generate 177Lu; 4, when the 177Lu generated by the
irradiation of the 176Lu in the target box reaches the designed saturation
specific activity, transporting the target box to a post-irradiation target
storage tank outside the reactor core; and 5, during the operation period of the
pressurized water reactor, repeating the steps 2-4 until the reactor is
shut down. The method has the beneficial effects that the single
irradiation time of the target boxes can be controlled through analysis, so that a plurality of target boxes can be irradiated in a single refueling period of the pressurized water reactor, and the yield of 177 Lu is greatly improved.