This invention discloses a method for designing and fabricating a personalized artificial
intervertebral disc prosthesis, belonging to the field of artificial
intervertebral disc prosthesis technology. The invention aims to solve the problems of poor mechanical adaptability, lack of biomimetic structure, and design-manufacturing disconnect in existing prostheses. The steps include: S1, collecting kinematic and
dynamic data of the
lumbar spine under healthy conditions to obtain the torque-rotation curve of the target
vertebral segment; S2, establishing and validating a finite
element model based on MRI / CT, with motion deviation within 5%; S3, constructing a biomimetic
intervertebral disc including a biomimetic
nucleus pulposus, transition zone, annulus fibrosus, and endplate, wherein the number,
diameter, stiffness gradient, and arrangement of biomimetic fibers are adjustable; S4, establishing a quadratic regression equation with the target curve as the optimization target to obtain optimal parameters with a matching degree ≥90%; S5, using multi-material additive manufacturing for integrated molding. This invention achieves individualized stiffness matching and biomimetic structure
reproduction, improves fatigue and
shear resistance, and is suitable for personalized customization of the
lumbar spine.