63 results about "Bone transplant" patented technology

An injectable and moldable putty comprising biodegradable calcium-based compounds including calcium sulfate, hydroxyapatite, and tricalcium phosphate is invented. The putty hardens into a solid body when mixed with water, saline, serum, or other neutral aqueous solutions. The hardening time of the putty can be tailored in order to meet the specific requirements of various dental or orthopedic applications. The pH of the putty is neutral during and after mixing. The invented putty may be used as bone graft, bone implant, or implantable drug delivery device.

In various exemplary embodiments, the present invention provides a set of less invasive cervical spine instruments that are used to achieve cervical disc decompression, bone preparation, and the alignment of one or more matched sized bone grafts prior to cervical plate placement. This set of less invasive cervical spine instruments, and the related surgical method, result in reduced surgical time, the preparation of a precise machined bone surface while simultaneously maintaining the cervical disc decompression height of the intervertebral endplates, the selection of one or more prefabricated bone dowel grafts sized to match the machined bone surface and maximizing the surface contact required for cervical spine fusion, the placement of the one or more prefabricated bone dowel grafts (e.g. side by side) that can be of different diameters in order to fully exploit the intervertebral space available, and the alignment of the cervical plate using a cervical spine instrument that is matched to align with the one or more prefabricated bone dowel grafts beneath the cervical plate.

The present invention discloses an injectable-porous-drug loaded polymethyl methacrylate-based composite scaffold bone transplant material and a preparation method thereof, and belongs to the field of organic functional materials preparation. The polymethyl methacrylate-based composite scaffold bone transplant material uses polymethyl methacrylate (PMMA) as a scaffold for providing mechanical supporting, and a chitosan-based thermosensitive hydrogel as a pore forming agent and an osteoconductive material and a drug carrier, and the polymethyl methacrylate (PMMA) and the chitosan-based thermosensitive hydrogel are mixed with each other to form an injectable-porous three-dimensional structural bone cement composite. The scaffold bone transplant material is simple in preparation method, suitable in reaction temperature, and good in biocompatibility, has matched mechanical properties, good biological mineralization and corresponding anti-bacterial, anti-inflammatory or anti-tumor capabilities, and has broad prospects in clinical application of reconstruction of bone tissues in future.

The invention discloses a large-aperture bone regeneration bracket material and a preparation method thereof, and belongs to the technical field of medical biomimetic material engineering. A natural porous inorganic biological material (cuttlebone) and ammonium dihydrogen phosphate undergo a full reaction at high temperature under high pressure so as to be transformed into a multi-phase biological ceramic (consisting of calcium carbonate, hydroxyapatite and calcium phosphate). The preparation method for the material is simple in process, the material source is abundant, and the cost is low. In addition, the prepared material has good biological compatibility and high compression strength, and is environmentally-friendly. The bone cell experiment shows that the material has bone conduction activity, can promote and induce bone regeneration self-repair, can be degraded step by step in vivo, is an ideal bone transplant replacement material, and has wide application range and obvious social and economic benefits in bone surgical operation.

The invention provides a tubular tool for acquiring a human vein transplant in a minimally invasive manner. The tubular tool comprises a tubular tool bit, a tunnel tube and a handle which are sequentially connected and is characterized in that one end of the tool bit is an edge; the inner wall of the tool bit is provided with an annular protruding part which is close to the side, with the edge, ofthe tool bit. The tubular tool has the advantages that the vein transplant can be acquired in an minimally invasive manner, a large skin cut is avoided, and the tubular tool is fast to operate, simple, practicable, capable of saving time and labor and capable of greatly reducing medical treatment cost and the wound of a patient; a long skin cut and a large subcutaneous tissue wound are avoided, the tubular tool rotates and moves forwardly to separate the vein from peripheral tissue and cut off vein peripheral collateral branches while the main part of the vein transplant is kept intact, the main part of the vein transplant is guided into the tunnel tube, the vein is cut off and the transplant is taken out after required acquiring length is reached, and a minimally invasive effect is guaranteed.

The present invention relates to an apparatus and method for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The integrated fusion cage and graft delivery device according to various embodiments delivers and disperses biologic material through a fusion cage to a disc space and, without withdrawal from the surgical site, may selectively detach the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area. In one embodiment, the integrated fusion cage is an expandable integrated fusion cage.

Apparatus is provided that includes a surgical tool for use with solid particles and a physiological liquid solution. The surgical tool includes (a) a shaft unit, which is shaped so as to define a delivery lumen, and a distal opening, which is disposed within 10 mm of a distal end of the shaft unit, in fluid communication with the delivery lumen; (b) a composition source, which is coupled in fluid communication with the delivery lumen, and which is configured to provide a solid-liquid composition of the solid particles and the physiological liquid solution; and (c) a pump, which is configured to pump the solid-liquid composition through the distal opening via the delivery lumen.

The present invention relates to an apparatus and method for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The integrated fusion cage and graft delivery device according to various embodiments delivers and disperses biologic material through a fusion cage to a disc space and, without withdrawal from the surgical site, may selectively detach the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area. In one embodiment, the integrated fusion cage is an expandable integrated fusion cage. In another embodiment, the bone graft material is loaded into a breech area in the hollow tube.

An ultrasound transmitter device for treating a patient is provided. The ultrasound transmitter device includes an imaging probe; an imaging array; and a therapeutic ultrasound device, wherein the imaging probe is configured to guide the therapeutic ultrasound device to the patients treatment site by use of ultrasound imaging with the imaging array, wherein the therapeutic ultrasound device is configured to produce a controlled intensity of ultrasound energy for treating the patients treatment site, and wherein the imaging probe and the therapeutic ultrasound device are configured to work in conjunction with one another to apply therapeutic ultrasound to tissue or bone graft sites in the patient.

A method and system for making a preformed dental membrane using three-dimensional (3D) patient data. A patient jaw having insufficient bone at a surgical site may be scanned to provide a 3D image which may be used to design a virtual preformed dental membrane and fabricate for placement over packed bone graft substitute.

The invention discloses a material of calcium alginate liquid colloid. The material of the invention is prepared by the steps that manutex particles precisely weighed and packaged are radiated for 1000min by 10K Gy Co<60> for sterilization; sterilized triple-distilled water is served as a solvent to be made into 3 percent of 10ml water solution; 3 percent of 1.7ml CaCl2 is added and evenly blended under the constant stirring by a magnetic rotor at the room temperature of 25DEG C; 0.1M acetic acid solution titration is added until the pH is 7 in the liquid colloid, wherein, the sterilized triple-distilled water can be sterilized DMEM culture fluid alternatively. The material of calcium alginate liquid colloid of the invention is used for being injected into a bone bioreactor at the subperiosteum cavity in a human body to induce osteogenesis and has good biocompatibility, strong flexibility, good quality of osteogenesis, low cost and great potential in bone transplant with simple operation without being cultured by external cells and adding cell factors or growth factors, is absorbable in the human body, meets the demands of mechanical support and stimulus of the closed subperiosteum cavity, and also ensures no risks of infection, immune rejection and the like. Therefore, the invention provides the good scaffold material for the bone bioreactor.

The invention discloses a 3D printing bone platform and belongs to the field of 3D printing. The 3D printing bone platform comprises an upper bracket and a lower bracket which are movably connected with each other, wherein the upper bracket is of square shape; the bottom of the lower bracket is of square shape; the lower bracket comprises four support rods along the vertical direction; the vertex of the upper bracket is connected with the vertex of the bottom of the lower bracket through the support rods; the support rods are moveably connected with the upper bracket; the upper bracket can be overturned around the joint point; a print head is arranged on the upper bracket; a fusing device is fixedly arranged above the lower bracket; the fusing device is connected with the print head through a sampling pipe. The 3D printing bone platform provided by the invention has excellent biocompatibility and can supply growth cavity to the tissue cells; the print bone transplanted into the biological body can survive and be integrally fused with the transplant receptor; the printing precision is ultrahigh; the platform can correct at any time and accurately control the flow, so that the artificial bone completely matched with the original bone system can be acquired.

The present invention relates to a method for producing a bone transplant material using an extracted tooth, and to a bone transplant material produced by same, and particularly, to a method for producing a bone transplant material which enables the production of bone transplant material in a short amount of time using an extracted tooth of a patient or a similar tooth.

The invention provides a bone graft implant and a preparation method thereof. A decalcified bone matrix is used as a basic material; collagen in the decalcified bone matrix is subjected to a thermal cross-linking reaction, and collagen in the decalcified bone matrix and glycosaminoglycan are subjected to a thermal cross-linking reaction so as to obtain a bone graft implant. According to the invention, mechanical strength and degradation period of the bone graft implant are enhanced, which promotes cartilage cell conversion. The product can be used as the bone graft implant to be applied to nasal plastic surgery and other surgeries, and can replace autologous cartilage tissues to be used for comprehensive rhinoplasty under the condition that a patient is unwilling to use the autologous cartilage tissues or the autologous cartilage tissues is not applicable.