Composite vitamin B powdery injection for venous infusion and preparation thereof
A technology for injection powder and multivitamin, which is applied in the field of compound vitamin B powder injection and preparation, and can solve the problems of short storage time, easy oxidation reaction, poor drug stability, etc.
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Embodiment 1
[0016] Formula: Vitamin B 1 20g
[0017] Riboflavin Sodium Phosphate 2.74g
[0018] Vitamin B 6 2g
[0019] Niacinamide 30g
[0020] Sodium D-pantothenate 1g
[0021] Edetate Disodium 0.2g
[0022] Low Molecular Dextran 40 20g
[0023] A total of 1000 pieces were made
[0024] The preparation process includes pretreatment: under the condition of 10,000 grades, heat and dissolve the prescribed amount of low-molecular dextran 40 with 50-200ml water for injection, add activated carbon to boil, keep stirring for 20-30 minutes, filter while it is hot, and let the filtrate cool as a pretreatment solution.
[0025] Ingredients: add water for injection to the pretreatment solution to 50-90% of the ingredients, add 0.1-1g of edetate disodium and stir to dissolve, then add the prescribed amount of vitamin B 1 , Vitamin B 6 , Niacinamide and D-pantothenic acid...
Embodiment 2
[0032] Formula: Vitamin B 1 20g
[0033] Riboflavin Sodium Phosphate 2.74g
[0034] Vitamin B 6 2g
[0035] Niacinamide 30g
[0036] Sodium D-pantothenate 1g
[0037] Edetate Disodium 0.2g
[0038] Mannitol 20g
[0039] A total of 1000 pieces were made
[0040] Preparation process: except that the auxiliary materials added are different, others are the same as in Example 1
Embodiment 3
[0042] Formula: Vitamin B 1 20g
[0043] Riboflavin Sodium Phosphate 2.74g
[0044] Vitamin B 6 2g
[0045] Niacinamide 30g
[0046] Sodium D-pantothenate 1g
[0047] Edetate Disodium 0.2g
[0048] Cyclodextrin 20g
[0049] A total of 1000 pieces were made
[0050] Preparation process: except that the auxiliary materials added are different, others are the same as in Example 1
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