The invention discloses a radial tyre bladder and a preparation method of the radial tyre bladder, belonging to the technical fields of compositions of macromolecular compound and preparation methods. The radial tyre bladder comprises the following raw materials by weight: 90-110 parts of butyl rubber, 5-6 parts of chloroprene rubber, 4-6 parts of castor oil, 48-55 parts of carbon black, 0.7-1.5 parts of stearic acid, 0.4-0.8 parts of paraffin, 7-10 parts of resin, and 4-6 parts of zinc oxide. The method comprises the following steps: (a) preparing ingredients, mixing and filtering: mixing the semi-finished rubber and zinc oxide at 50-60 DEG C for 40-50 seconds, adding the resin and mixing for 60-70 seconds, adding other additives, raising the temperature to 150-160 DEG C, mixing for 7-8 minutes to obtain a mixture, and standing for 12-24 hours; (b) extruding to obtain slices and forming rubber strips; (c) vulcanizing and polishing, wherein the vulcanization temperature is 160-170 DEG C and a pressure-maintaining and temperature-preservation process is performed for 3-5 minutes. According to the technical scheme of the invention, the production efficiency is improved, the heat resistance of the rubber is increased, and the service life of the tyre bladder is prolonged.