160 results about "Insulin injection" patented technology

An automated insulin delivery system provides an insulin injection that is computed by adding (i) the recommendation of an artificial neural network trained to mimic a constrained model predictive controller dosing rule from a neural network implementing an artificial pancreas (ii) a hypoglycemia mitigation system includeds a correction (one dose computed as the correction down to 110mg / dl based on prevailing continuous glucose monitoring and once an hour at most, unless there is a triggering BPS and G>180 mg / dl), and (iii) the current basal rate (output of the Performance Assessment System, (PAS)); that amount is then saturated by the Safety Supervision System, SSM. Finally, a priming bolus from the Bolus Priming System, BPS, is added to the total if the conditions for large glycemic excursions are detected, also saturated by SSM.

A diabetes management system adapted to determine adherence for a subject in treatment according to a basal insulin regimen, the system being adapted to receive regimen data. BG data and insulin injection data. If one or more insulin injections have not been received in accordance with the prescribed regimen and thus are missing, the system is adapted to calculate for each missing injection an expected dose response BG value. By comparing received BG data, corresponding to the missing insulin injections, it can be determined for a given confidence interval whether or not the subject has been in adherence with the basal insulin regimen.

A mathematical model of type 1 diabetes (T1D) patient decision-making can be used to simulate, in silico, realistic glucose / insulin dynamics, for several days, in a variety of subjects who take therapeutic actions (e.g. insulin dosing) driven by either self-monitoring blood glucose (SMBG) or continuous glucose monitoring (CGM). The decision-making (DM) model can simulate real-life situations and everyday patient behaviors. Accurate submodels of SMBG and CGM measurement errors are incorporated in the comprehensive DM model. The DM model accounts for common errors the patients are used to doing in their diabetes management, such as miscalculations of meal carbohydrate content, early / delayed insulin administrations and missed insulin boluses. The DM model can be used to assess in silico if / when CGM can safely substitute SMBG in T1D management, to develop and test guidelines for CGM driven insulin dosing, to optimize and individualize off-line insulin therapies and to develop and test decision support systems.

The utility model discloses a multifunctional insulin injection device which comprises an insulin injection pen, a needle tube is fixedly arranged at the lower end of the insulin injection pen, an injection needle is fixedly arranged at the lower end of the needle tube, and a pen cover is movably arranged at the lower end of the insulin injection pen in a clamped mode. A disinfection mechanism used for disinfecting an injection area is arranged at the lower end of the pen cap and comprises a fixing ring, a protective shell, a rubber sleeve and a cotton brush head, the fixing ring is fixedly arranged at the lower end of the pen cap, the protective shell is arranged on the outer side surface of the fixing ring, and the rubber sleeve is fixedly arranged at the position, inside the fixing ring, of the lower end of the pen cap. A cotton brush head is fixedly arranged at the lower end of the rubber sleeve. The insulin injection pen is good in using effect and complete in functionality, the disinfection function is additionally added, an injection area can be disinfected before injection, then injection is conducted, the disinfection function and the insulin injection pen are integrated, and the insulin injection pen is convenient to carry and use and complete in functionality.

The utility model relates to an auxiliary fixing device for injection, which comprises a fixing frame, two sides of the fixing frame are respectively provided with a binding belt, one end of one binding belt is provided with a locking buckle matched with the other binding belt, and the other end of the other binding belt is provided with a locking buckle matched with the other binding belt. Two corresponding kneading rollers are installed on the side, close to the abdomen, of the interior of the fixing frame, in the using process, after a part needing injection is confirmed, the abdomen can be squeezed under the action of the two kneading rollers, and the skin in the corresponding area is made to protrude towards the rubber cover; meanwhile, under the action of a plurality of elastic mechanisms, the rubber cover is tightly attached to the upheaval part of the abdomen, then a user inserts an insulin injection pen into the upheaval part from the interior of a limiting barrel, in this way, insulin can be correctly injected into the body of a patient, and the situation that the patient is pricked askew during injection is reduced; and a patient can accurately pierce into a part needing to be injected, so that more convenience is brought to people.

An insulin needle extractor is characterized in that a sleeve-shaped shell is designed, the inner cavity of the sleeve is used as a channel, a claw sleeve composed of at least two elastic claws is designed for the channel, a slope or a taper is arranged between the inner wall of the channel of the shell and the outer side of the claw sleeve, the claw sleeve is inserted into the channel of the shell, and the elastic claws are forced to present two working states of opening and contraction relative to the center of the channel during the sliding of the claw sleeve before and after the channel. When the needle is removed, the insulin needle is inserted from the needle removal port in the open state of the elastic claws, and the claw sleeve is moved to the other end in the channel, the elastic claws are forced to contract to the center during the movement due to the effect of the slope or the taper, and the insulin needle is clamped, at this time, the needle extractor can be rotated in the reverse direction until it is separated, and the insulin needle can be removed from the head of the insulin injection pen. The present scheme only has the cooperation of the shell and the needle extraction sleeve (the claw sleeve), has few parts, simple structure, and reliable work.

The invention relates to the technical field of intelligent diabetes treatment instruments, in particular to a closed-loop non-invasive insulin detection and precise infusion system which is characterized by comprising a blood glucose monitoring regulator, a non-invasive injector and a closed-loop control mechanism. The closed-loop control mechanism comprises a real-time blood glucose detection module, a temperature detection module, a blood glucose data processing module, a dose decision module, an injection pressure adjusting module, an injection channel control module, an insulin injection module and a closed-loop feedback module; noninvasive and high-sensitivity real-time blood glucose monitoring is achieved, the accuracy and timeliness of insulin administration are improved through trend prediction and individualized dose decision, meanwhile, multi-nozzle array piezoelectric needleless injection is combined with temperature compensation pressure regulation and a closed loop feedback correction mechanism, local tissue burden is effectively reduced, and the insulin administration efficiency is improved. And through multiple safety protection and wireless data transmission, remote monitoring and intelligent management are realized, so that the convenience, accuracy and reliability of blood glucose management of diabetic patients are greatly improved.

The utility model relates to the technical field of insulin injection, in particular to a disposable sterile insulin syringe. The disposable sterile insulin syringe comprises a syringe barrel, a connecting pipe, a needle head, a stress plate, a piston, a push rod and a push plate, the left end of the syringe barrel is connected with the connecting pipe, the connecting pipe is connected with the needle head, the right end of the syringe barrel is connected with the stress plate, the push rod is connected into the syringe barrel in a sliding mode, and the piston is connected with the push rod. The left end of the push rod is connected with a piston, the right end of the push rod is connected with a push plate, a groove is formed in the lower side of the right end of the push rod, the connecting block is placed in the groove, and the left side of the lower portion of the stress plate is connected with the limiting block and the elastic piece. Through the arrangement of the connecting block, the limiting block and the elastic piece, the push rod can be braked through simple operation, it is ensured that the push rod is not prone to being pulled after an injector is used, medical workers are prompted that the injector is used, and the risk of repeated use is reduced.

The images related to this design are used, for example, to monitor, display, or track measurement data such as blood glucose levels, as well as exercise, insulin administration, and food intake. These images can be operated by tapping, pressing, swiping, or scrolling the display screen, or via other devices associated with the display device.

The injection pump comprises an insulin pump body and further comprises a medicine storage device, a medicine changing assembly, an exhaust device and a medicine pushing assembly, the medicine storage device is detachably connected with the insulin pump body, a plurality of medicine bags are placed in the medicine storage device, the medicine changing assembly is arranged in the medicine storage device, the medicine changing assembly is pressed, and the medicine pushing assembly is arranged in the medicine storage device. The medicine changing assembly automatically changes the medicine bag, the exhaust device is arranged in the insulin pump body and automatically exhausts air after the medicine bag is replaced, the medicine pushing assembly is arranged in the insulin pump body and pushes the medicine bag, and insulin injection in the medicine bag is completed. The device has the advantages that the medicine storage device is used for storing multiple tubes of insulin, the storage amount of the insulin is increased, the medicine changing assembly is used for achieving automatic medicine changing, the medicine changing process is simplified, the medicine changing time is shortened, the exhaust device is used for achieving automatic exhaust of the insulin after changing, the situation that an indwelling needle needs to be pulled out in the insulin changing process is avoided, and repeated needle inserting is avoided; and the comfort of the patient is improved.

The invention discloses an insulin injection data management system, which relates to the technical field of medical health information and comprises a data acquisition module for acquiring injection operation data and blood sugar data from an insulin injection pen and lifestyle data input by a user; the intelligent analysis module is used for generating insulin dose recommendation information through a predefined dose calculation model on the basis of the injection operation data, the blood glucose data and the life style data, and generating injection site rotation recommendation information on the basis of injection site information in the injection operation data; the early warning prompt module is used for generating and outputting a dose early warning and a failure early warning based on dose information and temperature information in the injection operation data; and the medical care collaboration module is used for providing a data access interface for authorized medical care personnel and adjusting parameters of the dose calculation model based on remote instructions of the medical care personnel. And accurate and dynamic recommendation of dosage, scientific alternating guidance of injection parts and active early warning of dosage and failure are realized.

An insulin delivery device includes an insulin injection device in communication with a controller for controlling the insulin injection device. The controller is configured to receive a heart signal from one or more heart sensors, and a blood glucose signal from one or more blood glucose sensors. The controller is further configured to analyze changes in the heart rhythm of the subject based on the heart signal and determine, based on the changes in the heart rhythm and the blood glucose signal, whether the subject is and / or will be experiencing an adverse event. Upon determination that the subject is or will be experiencing an adverse event, the controller determines one or more parameters of delivery of insulin to be delivered to the subject. Finally, the controller is configured to control the injection device to deliver insulin to the subject in accordance with the determined one or more parameters of delivery.

A kind of pen core screw rod pump for insulin injection, shell, pen core injection mechanism, primary screw rod telescopic mechanism, secondary screw rod telescopic mechanism, power device, power module and intelligent control module, power device is connected with primary screw rod telescopic mechanism transmission, secondary screw rod telescopic mechanism is installed in primary screw rod telescopic mechanism and is connected with primary screw rod telescopic mechanism transmission, pen core injection mechanism is set in the upper portion of secondary screw rod telescopic mechanism, key operation module is equipped on the shell, sensor assembly is set on primary screw rod telescopic mechanism, power module provides power to power device and intelligent control module respectively, and intelligent control module is connected with power device, key operation module and sensor assembly signal respectively.This application can accurately control the injection amount of insulin liquid, realize high-precision drug delivery, significantly reduce the overall size, the rotation torque and speed of intelligent control power motor, reduce the impact degree, reduce the energy consumption of electric energy, also have anti-lock function.

The invention discloses an insulin sterile injection device for diabetics in the field of insulin injection, which comprises two mounting frames, side brackets are arranged at the upper parts of the sides close to each other, and a middle bracket is arranged between the two side brackets; the left end and the right end of the middle support are connected with the corresponding side supports through height adjusting assemblies respectively, a moving seat capable of moving transversely is arranged on the middle support, an injection positioning mechanism capable of swinging front and back is arranged on the moving seat, and an injector is installed on the injection positioning mechanism. A plurality of transverse connecting belts are connected to the outer sides of the two mounting frames, the outward end of each connecting belt on the left side is fixed to the first fixing part, and the outward end of each connecting belt on the right side is fixed to the second fixing part. The sterile insulin injection device can achieve sterile insulin injection, and injection part infection caused by nonstandard operation is avoided.

The utility model relates to the technical field of insulin injection pens, and discloses an insulin injection pen capable of preventing a needle from being punctured, which comprises an injection pen body and a pen cap, the injection pen body is in threaded connection with a needle seat, the needle seat is fixedly connected with a connecting block, the connecting block is rotatably connected with a first protective shell, and the first protective shell is fixedly connected with the pen cap. According to the insulin injection pen capable of preventing the needle from being punctured, when the insulin injection pen capable of preventing the needle from being punctured is used, injection is conducted or the needle is replaced, the first protective shell and the second protective shell can be opened and closed through the action of pulling the pull ring and the spring, and therefore the insulin injection pen can be used for preventing the needle from being punctured. The needle head is effectively covered and prevented from being exposed, the puncture risk caused by accidental contact of medical staff, patients or other people is greatly reduced, the needle head is replaced by screwing the needle base, the replacement process is simple and rapid, meanwhile, the sealing performance of the needle head is kept, and sanitation and safety of injection are guaranteed.

This application discloses an insulin pen packaging box, relating to the field of pharmaceutical packaging technology. Its key technical features are: an outer box body composed of a box body and a freely opening and closing lid; a paper tray embedded inside the box body, the projection of the paper tray on the horizontal plane coinciding with the bottom of the box body; the paper tray includes a pad, on which multiple insulin pen placement frames are arranged side-by-side, and each placement frame is fixedly connected to the pad; each end of a placement frame has a slot along its length, and when an insulin pen is placed in a slot, the slot provides support and restraint to the end of the insulin pen. This allows for the simultaneous storage of multiple insulin pens within a single packaging box, thus improving packaging efficiency and patient convenience.

The utility model relates to the field of medical auxiliary devices, in particular to an insulin injection site alternation prompting device, which is characterized in that four graphic sheets of a graphic sheet assembly on which four different regional patterns of a human body are drawn are fixedly connected to four side surfaces of a box body, and respective insulin injection permitting sites are drawn in the regions drawn by the four graphic sheets; setting a plurality of injection point positions with unique identification character codes in respective injection parts; the plurality of lamp beads are respectively arranged on the plurality of injection point positions; a plurality of injection positioning holes with identification character codes are respectively formed in four groups of positioning cards of the positioning clamping piece, the plurality of injection positioning holes are in one-to-one correspondence with a plurality of injection point positions of the graphic sheet combined piece, and the identification character codes of the plurality of injection positioning holes are the same as the identification character codes of the respective corresponding injection point positions; by means of automatic prompting of the device, a patient can be helped to timely master injection time and injection positions and injection points needing to be changed each time, and risks affecting the treatment effect can be reduced.

Describes devices, systems, and techniques for controlling the delivery of diabetes therapies. In one example, the system includes: a wearable device configured to generate user activity data associated with a user's arm; and one or more processors configured to: identify, based on the user activity data, at least one gesture indicative of preparing an insulin injection using an injection device; generate, based on the at least one identified gesture, information indicative of at least one of an amount or type of an insulin dose in the insulin injection performed by the injection device; compare the generated information with a standard for an appropriate insulin injection; and, based on the comparison, output information indicative of whether the standard is met.

1. The name of the design product: insulin injection simulation artificial skin. 2. The use of the design product: the product is mainly used to demonstrate injection site selection and injection process in subcutaneous injection education process. 3. The design points of the design product: the combination of shape, pattern and color. 4. The picture or photo that best indicates the design points: perspective view. 5. The design for which protection is sought contains color. 6. The back of the design product is a part that is not easy to see or cannot be seen during use, and the rear view is omitted.

The utility model discloses a novel portable insulin injection pen cold storage device, which relates to the technical field of medical instruments, and comprises a heat preservation cylinder, a plurality of storage cylinders, a plurality of storage cylinders, a plurality of storage cylinders and a plurality of storage cylinders, the semiconductor refrigeration part is connected into the heat preservation cylinder, and the refrigeration end of the semiconductor refrigeration part is attached to the storage cylinder and used for refrigerating insulin; the heat dissipation plate is connected into the heat preservation cylinder, and one side of the heat dissipation plate is attached to the heat dissipation end of the semiconductor refrigeration part; insulin injection pens in the storage barrels distributed in a circumferential array mode can be refrigerated at the same time, it is ensured that all the pens are in a suitable low-temperature environment, insulin is effectively stored, heat of the semiconductor refrigeration parts is conducted through the heat dissipation plate, the heat dissipation fan promotes air to flow to take away the heat, stable work of the refrigeration parts is maintained, and the continuous refrigeration capacity is ensured; the device is convenient to store, a patient can conveniently place the injection pen to be cooled, and insulin can be conveniently stored when the injection pen is daily used and carried outdoors.

1. Name of the design product: Insulin syringe. 2. Use of the design product: For insulin injection. 3. Design key points of the design product: Lies in the shape. 4. Picture or photo that best shows the design key points: Stereogram.

Provided is a personalized artificial intelligence-based insulin dose determination system for a terminal which can communicate with an insulin pump and a continuous blood glucose meter used by a user, the personalized artificial intelligence-based insulin dose determination system comprising: an interface layer which can communicate with the insulin pump and the continuous blood glucose meter, and signal-processes information from the insulin pump and the continuous blood glucose meter; a control layer which receives the signal-processed information from the interface layer and generates output information associated with an insulin injection amount; an outer safety layer which determines whether the output information generated from the control layer satisfies a preset threshold value condition, and if the output information satisfies the preset threshold value condition, transfers the output information to the interface layer; and a personalized safety layer which determines a safety control variable per individual by receiving, from the outside, prescription information including the total daily dose (TDD) of insulin information of a user, and transmits the determined control variable as an input variable of the control layer.

The utility model discloses an insulin injection pen, and belongs to the technical field of medical instruments. Comprising a main body shell, a connecting sleeve and a medicine bin, and the main body shell is connected with the medicine bin through the connecting sleeve; the adjusting mechanism comprises a dosage rotating cylinder and a transmission pipe, the dosage rotating cylinder is arranged in the main body shell and is in threaded connection with the main body shell, and the transmission pipe is arranged in the dosage rotating cylinder and is in clutch connection with the dosage rotating cylinder; the driving mechanism is arranged in the transmission pipe, and the driving mechanism is matched with the connecting sleeve to form an injection sound production structure; the insulin injection pen is switched from a dose adjusting state to an injection state through up-down separation and reunion of the transmission tube, and injection administration is performed through the driving mechanism. The connecting sleeve is made of a plastic part with high hardness, even if the medicament bottle gives reactive force to the driving mechanism during injection, the matching precision between the driving mechanism and the connecting sleeve is not affected, the reliability of the injection sound production structure is improved, and the problem of deformation or failure possibly occurring after the reactive force during long-term injection administration is avoided.

The invention discloses a method for constructing a prediction model for subcutaneous fat hyperplasia caused by insulin injection. The method comprises the following steps: S1, selecting a plurality of participants for questionnaire survey according to inclusion standards; s2, performing ultrasonic inspection on all participants; s3, performing feature screening on the predicted variables by adopting LASSO regression; s4, developing a fat hyperplasia prediction model by using three algorithms of random forest, extreme gradient lifting and logistic regression, and selecting the fat hyperplasia prediction model with the optimal performance for research; and S5, explaining the influence of the predictive variables on the fat hyperplasia prediction model through an SHAP method. According to the method, a machine learning-based insulin injection-induced fat hyperplasia prediction model is created, the constructed extreme gradient lifting machine learning model shows relatively high efficiency in the aspect of predicting the occurrence of fat hyperplasia of the diabetic patient, and the diabetic patient with high-risk fat hyperplasia can be accurately identified.

The invention provides an insulin injection pen, and belongs to the technical field of injection pens. An operation unit including a housing; the injection pen further comprises a connecting piece and a separating piece which are arranged in the shell, the connecting piece is detachably connected with the medicine bin, the separating piece is connected with the shell, in the normal use process of the injection pen, the relative positions of the connecting piece and the separating piece are not changed, and the connecting position of the connecting piece and the medicine bin is located in the shell. A first threaded hole is formed in the connecting piece, a second threaded hole is formed in the separating piece, the first threaded hole and the second threaded hole are coaxial, and the medicine bin, the connecting piece and the separating piece are sequentially arranged and distributed; the material pushing screw rod is located in the shell and is in threaded connection with the first threaded hole and the second threaded hole, and a separation part is arranged at the first end of the material pushing screw rod; the device has the advantages that after the medicine bin is separated from the shell, the joint of the connecting piece and the medicine bin is exposed in the view field, the connecting piece and the medicine bin can be separated by disconnecting the connecting piece and the medicine bin, the operation unit and the medicine bin which are made of different materials can be treated or recycled according to the material characteristics, and environmental protection is facilitated.

The invention relates to a small-dose automatic metering, subpackaging and storing device and a control method thereof, and relates to the technical field of medical medication configuration and intravenous infusion dosing assistance. The intelligent metering injection unit is arranged in the shell and is used for fixedly mounting a disposable syringe; the piston displacement detection assembly is used for detecting piston displacement in real time; the piston driving and locking mechanism is used for driving the piston of the disposable syringe to automatically shift and be locked at a target dose position; the main control module is used for calculating the actual dose according to the piston displacement; wherein the intelligent metering injection unit provides axial guidance for the disposable syringe, the main control module controls the piston driving and locking mechanism according to the actual dose calculated by the piston displacement detection assembly, and closed-loop metering is achieved. High-precision control over insulin small-dose intravenous dosing can be achieved, the pollution risk caused by pumpback or repeated puncture is avoided, and the actual use loss of insulin injection is reduced on the whole.

The utility model discloses auxiliary equipment convenient for insulin injection, which relates to the technical field of medical assistance and comprises an equipment main body, a through hole is arranged above the back of the equipment main body, and a color distinguishing strip is connected above the outer surface of the equipment main body. Through the arrangement of the color distinguishing strip, the first distinguishing plate, the second distinguishing plate and the date distinguishing block, the seven iridescent colors on the color distinguishing strip correspond to the characters from the weekly one to the weekly day on the date distinguishing block respectively, and therefore the position needing to be injected on the day is determined, for example, insulin injection needs to be conducted in the weekly one; if not, a red color distinguishing strip is arranged or a date distinguishing block in a round-line shape is arranged, and insulin injection should be carried out on the left upper abdomen; according to the insulin injection device, mistaken injection, missed injection and mistaken injection of insulin injection can be reduced, subcutaneous induration caused by improper insulin injection of a diabetic patient is reduced, and complications such as infection, bruise and subcutaneous lipoatrophy of an injection part are reduced.

The application discloses a kind of sterile insulin injection devices for diabetic patients in the field of insulin injection, including two the installation frame mutually close one side upper portion It is provided with side support on each, it is provided with middle support between two side supports, the left and right ends of the middle support are connected with corresponding side support respectively via a height adjusting assembly, it is provided with the movable seat that can move transversely on the middle support, it is provided with the injection positioning mechanism that can swing position forward and backward on the movable seat, the injector is installed on the injection positioning mechanism;The outside of two the installation frame is connected with several transverse coupling belts, the outward end of each coupling belt on left side is fixed with fixed part one, the outward end of each coupling belt on right side is fixed with fixed part two.The application can realize sterile insulin injection, avoid the infection of injection site caused by non-standard operation.

The utility model provides a multifunctional refrigeration box which comprises a box body, a box cover and a box cover. An upper cover; a bracket; the heat preservation device is supported on the bracket and is used for supporting and placing an insulin injection pen; the needle head fixing piece is arranged in the box body and located below the heat preservation device, and the needle head fixing piece is used for fixing a needle head; the temperature detection element is arranged in the heat preservation device and used for detecting the temperature in the heat preservation device and sending the temperature to the control module; the alarm element is arranged in the box body and is used for giving an alarm prompt under the control of the control module; the charging panel is arranged in the box body, and a charging interface is formed in the charging panel; and the power storage module is arranged in the box body, is used for supplying power to the alarm element and the temperature detection element, and is connected with the charging panel. According to the multifunctional refrigeration box, the insulin injection pen and a plurality of insulin needles can be placed in the refrigeration box at the same time, the insulin injection pen in the refrigeration box can carry one insulin needle and one refill, the limited space in the box body is fully utilized to store a whole set of articles needed by insulin injection, and the multifunctional refrigeration box is compact in structure and convenient to carry. The heat preservation device is arranged in the cold storage box, and cold storage and heat preservation can be conducted on medicine in an insulin needle carried by the insulin injection pen.

The utility model provides a refrigeration box which comprises a box body, a box cover and a box cover. The bracket is arranged in the box body and is close to the upper end opening; the heat preservation device is supported on the support, and the insulin injection pen is arranged in the heat preservation device; the heat preservation device comprises a vacuum bin fixing piece which is rotationally connected with the support through a rotary connecting part, the vacuum bin fixing piece is provided with an inner cavity, and the end, away from the rotary connecting part, of the vacuum bin fixing piece is provided with an opening communicating with the inner cavity; and the vacuum bin is inserted into the inner cavity from the opening of the vacuum bin fixing piece, and a lining shell is fixedly arranged in the vacuum bin. According to the cold storage box, the heat preservation device comprising the vacuum bin fixing piece and the vacuum bin is arranged in the cold storage box, heat transfer is slowed down through the vacuum bin, the lining shell arranged in the vacuum bin is located in a relatively constant-temperature environment, and cold storage and heat preservation can be conducted on medicine in an insulin needle carried by an insulin injection pen.