8 results about "Artificial pancreas" patented technology

The invention relates to a device for distributing and receiving a population of pancreatic islets heterogeneous in size, the device comprising a matrix having a first face opposite a second face, characterized in that the matrix comprises concentric channels centered on a center O, the channels have an opening for receiving the pancreatic cells, the opening leading out onto the first face, the opening extending over the entire length (L) of the channel, the opening having a width (I) taken along the section Si, the device being configured such that the widths of the opening of two adjacent channels have an equal or increasing value moving away from the center O and such that the widths of the opening of a channel closest to the center O and of a channel furthest from the center O have an increasing value moving away from the center O. The invention relates to the field of implantable devices, in particular artificial pancreas devices.

The application discloses a personalized closed-loop artificial pancreas system, which comprises a detection module (100) for continuously detecting blood glucose values of a patient, an infusion module (102) for infusing insulin into the patient, and a program module (101) for controlling the detection module (100) and the infusion module (102). The program module (101) generates insulin infusion instructions according to the blood glucose values detected by the detection module (100) and controls the infusion module (102) to perform infusion. The program module (101) comprises a user interface. In response to an input of the patient, the program module (101) executes a corresponding meal mode function. The meal mode comprises a high-carbohydrate mode and a normal-carbohydrate meal mode. According to the input of the patient, the program module (101) executes the function of the high-carbohydrate mode or the normal-carbohydrate mode, so as to be applicable to people with different carbohydrate consumption habits, improve the adaptability of the closed-loop artificial pancreas to different people, and enable people with different carbohydrate consumption habits to maintain a satisfactory blood glucose control effect.

This invention discloses a closed-loop infusion system and method based on food image recognition. An imaging module acquires food images, and a food image recognition model analyzes these images to obtain food data. An insulin algorithm determines the patient's postprandial insulin infusion volume based on the food data and simulates the patient's postprandial blood glucose. While the artificial pancreas infuses insulin, real-time blood glucose data is monitored. The real-time blood glucose data is compared with the simulated blood glucose data, and the comparison results are used to correct the parameters of the insulin algorithm, making it more suitable for patients. This improves the accuracy and adaptability of the insulin algorithm and benefits the treatment of diabetes.

Distribution and reception device for a heterogeneous population of pancreatic cells, method and bioreactor The invention relates to a distribution and reception device for a heterogeneous population in size of pancreatic islets, comprising a matrix having a first face opposite a second face, characterized in that the matrix comprises concentric channels centered on a center O, the channels have an opening for receiving pancreatic cells, opening onto the first face, the opening extending over the entire length (L) of the channel, the opening having a width (l) taken according to section Si, the device being configured so that the widths of the opening of two adjacent channels have an equal or increasing value when moving away from the center O and that the widths of the opening of a channel closest to the center O and of a channel furthest from the center O have an increasing value when moving away from the center O.The field of implantable devices, in particular artificial pancreas. Figure for the abstract: Fig.1.

A system for managing a patient's glucose level includes a glucose sensor to generate and store data signals for measurements of the patient's glucose level made by the glucose sensor; an insulin pump; and sensor electronics operatively coupled to the glucose sensor, the sensor electronics comprising a memory storing one or more predetermined characteristics associated with the sensor electronics; and a computing device in electronic communication with the sensor electronics. The computing device comprises a processor configured to operate the sensor electronics to (i) receive the generated data signals, (ii) obtain the one or more predetermined sensor characteristics from the memory and (iii) execute a closed-loop algorithm to provide insulin delivery instructions to an insulin pump by at least using the data signals and predetermined characteristics.

A method for controlling glucose in a flexibly structured dual-hormone artificial pancreas that manages optional meal and / or exercise notifications using coordinated control actions, which comprises: measuring a plasma glucose signal; calculating an incremental plasma glucose measurement (y); defining a model for incremental plasma glucose; defining a carbohydrate intake as dependent on a carbohydrate content estimated by the patient; defining an expected postprandial incremental plasma glucose y*(s) depending on the insulin bolus administered; defining a corrected incremental plasma glucose y(s), a corrected insulin infusion u(s), and a corrected carbohydrate d(s) intake; defining a virtual control action µ(s), divided into regulatory actions µr and counter-regulatory actions µcr and calculating control actions using a 2-DOF feedback controller with a nominal value pre-filter Fr(s).

A bilaterally driven closed-loop artificial pancreas, includes: a detection module; an infusion module, the infusion module includes: a drug storage unit; a screw and a driving wheel provided with wheel teeth, the driving wheel driving the screw and the screw pushing a piston; a driving unit cooperating with the driving wheel, the driving unit including at least two driving portions; a power unit connected to the driving unit, the power unit outputting two forces in two directions on the driving unit; and a program module. The power unit is controlled by the program module. The artificial pancreas has higher infusion efficiency and can enhance user experience.

The invention discloses a closed-loop artificial pancreas system for safe infusion, during a long period of real-time blood glucose value loss, the closed-loop artificial pancreas system can enter a learning mode or a safe mode. Based on historical blood glucose values and finger blood glucose values, it continues to calculate the required insulin infusion amount for the patient and infuses an appropriate amount of insulin to the patient. It will not infuse an inappropriate amount of insulin or even interrupt insulin infusion due to the lack of real-time blood glucose value, avoiding life-threatening situations for the patient and benefiting the patient's treatment.