Method and system for tuning a closed-loop controller for an artificial pancreas

一种控制器、调谐因子的技术，应用在控制/调节系统、流量控制、药物的器械等方向，能够解决设定水平的过冲等问题

Inactive Publication Date: 2015-08-12
ANIMAS CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when a PID controller is tuned or configured to aggressively regulate a subject's blood glucose level, overshooting of the set level may occur, which is often accompanied by oscillations, which is highly undesirable in the case of blood glucose regulation

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  • Method and system for tuning a closed-loop controller for an artificial pancreas
  • Method and system for tuning a closed-loop controller for an artificial pancreas
  • Method and system for tuning a closed-loop controller for an artificial pancreas

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Embodiment Construction

[0050] The following detailed description should be read in conjunction with the accompanying drawings, in which similar elements in different drawings are numbered the same. The drawings, which are not necessarily to scale, illustrate selected embodiments and are not intended to limit the scope of the invention. This detailed description illustrates the principles of the invention by way of example and not limitation. This description will clearly enable one skilled in the art to make and use the invention, and describes various embodiments, adaptations, variations, alternatives and uses of the invention, including what is presently believed to be the best way to carry out the invention. model.

[0051] As used herein, the term "about" or "approximately" for any numerical value or range indicates a suitable dimensional tolerance that allows the portion or collection of components to perform for its intended use as described herein. Additionally, the terms "patient," "host,"...

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Abstract

Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed into the controller. The infusion pump is configured to deliver insulin to a subject. The glucose sensor is configured to sense glucose levels in the subject and provide output signals representative of the glucose levels in the subject. The controller is programmed receives signals from at least one of the glucose sensor and the pump and configured to issue signals to the pump to deliver an amount of insulin determined by a feedback controller that utilizes a model predictive control of the subject based on desired glucose levels, insulin amount delivered and measured glucose levels of the subject. The controller is also configured to deliver insulin using a tuning factor based on either one of an omission index module or a calibration index module.

Description

[0001] priority [0002] This application for patent claims the benefit of priority under 35 USC §§119 and 120 and the Paris Convention based on priority filing of U.S. Patent Application S.N.13 / 708032 (filed December 7, 2012) (attorney docket no. This patent application is hereby incorporated by reference as if fully set forth herein. Background technique [0003] Diabetes is a chronic metabolic disease caused by the inability of the pancreas to produce enough insulin, which leads to a decrease in the body's ability to metabolize glucose. This disorder causes hyperglycemia, which is excess glucose in the blood plasma. Persistent hyperglycemia and / or hypoinsulinemia is associated with a variety of severe symptoms and life-threatening long-term complications, such as dehydration, ketoacidosis, diabetic coma, cardiovascular disease, chronic renal failure, retinal damage, and limb amputation Risk of nerve damage. Since it is not currently possible to restore endogenous insulin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/168A61M31/00G16H20/17G16H50/20
CPCA61M5/14244A61M2205/3561A61M2230/201A61M2230/005A61M2205/3553A61M2005/14296A61M2205/3592A61M2209/01A61M2205/702A61M5/1723G16H50/20G16H20/17A61M5/168
Inventor D.菲南T.麦坎恩R.维努戈帕兰
Owner ANIMAS CORP
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