79 results about "Medication monitoring" patented technology

The present invention relates to assisting patients in the taking of medication, and to assisting third parties in accumulating information regarding patient medication intake. The invention may be embodied a system including a portable medication monitor used in association with an instrumented medication package to provide intake data acquisition and patient support functions. The system may further be connected to a computer or computer network allowing information distribution between the medication monitor and third parties, such as physicians or pharmacists.

The lack of safe, reliable, automated and clinically acceptable blood sampling has been the main problem precluding the development of real-time systems for blood analysis and subsequent closed-loop physiological function control. While the analysis of a static blood sample in laboratory conditions has been rapidly advancing in reliability and blood volume reduction, non-invasive real-time blood analysis performed in vivo (while the blood is circulating in the body) has been elusive and unreliable. In this study we propose an innovative idea for semi-invasive blood sampling and analysis, which resembles the operation of a mosquito. At a miniature scale the proposed system does penetrate the skin to extract a static blood sample for further analysis, but the extent of this penetration, and the fact that it can be made painless, is particularly attractive for such applications as automated glucose analysis for closed-loop control of insulin infusion (artificial pancreas), continuous drug monitoring, or even periodic DNA analysis for security and identification purposes. These design aspects are described, and a specific implementation, applying MEMS (Micro Electro Mechanical Systems) technology, is suggested. The proposed microsystem is a matrix of individually controllable e-Mosquito™ cells, packaged in a disposable patch and attached to the skin, could be an avenue for real-time semi-invasive blood analysis and diagnostics.

The present invention relates to a method of quantifying a subject's wake or sleep state, and more particularly to a higher resolution method of determining when a subject is awake or asleep. The present invention additionally relates more specific applications of this method, and a system for making these quantitative measurements. There are numerous embodiments of the present invention, which are envisioned, with a few of those listed below. The present invention relates to a method of analyzing a subject, and preferably a human subject to determine quantitatively when the subject is awake and when the subject is sleeping. The present invention has application for use with alertness devices, for use to better analyze sleeping disorders, anesthesia monitors, psychiatric and hypnosis medication monitoring, and for looking at the effect of various other therapies.

The invention provides a safe medication monitoring system and a monitoring method thereof. The system comprises: a database, a medication rule base, and a monitoring device. The database is used to store data information related to past medical history of a to-be-examined patient. The data information comprises: basic information of the to-be-examined patient, and disease information, examination results, medication information, allergic history, and treatment information of the patient in past medical history. The medication rule base is used to store safe medication rules. The monitoring device determines whether medicine in a medication prescription is safe for the to-be-examined patient according to the database and the data stored in the medication rule base, and generates early warning information when the medicine is determined to be not safe. The system and the method monitor medicine in a given medication prescription in time, so as to ensure safe medication.

A hand-held portable drug monitoring system to detect and quantitate cocaine and other organic drugs in saliva, sweat, and surface wipes by using an ion selective electrode or an array of ion selective electrodes. The ion selective electrode has a cast membrane reference electrode and a sensing electrode with a hydrophobic polymer, a plasticizer, and an ionophore selective for the organic drug to be tested. The ion selective electrode can be connected to a converter that coverts a voltage reading from the ion selective electrode to a quantitative drug concentration level. Also disclosed is the related method of using an ion selective electrode to detect an organic drug in saliva, sweat, and surface wipes, the method of testing electrical contact in an ion selective electrode, and the method of making a cast membrane reference electrode.

The invention relates to a medicine monitoring and medicine taking reminding system. The medicine monitoring and medicine taking reminding system comprises a medicine taking reminding device and a medicine monitoring device which can be fixed on a medicine container and is characterized in that when the medicine monitoring device detects that medicine is in a use state, the medicine monitoring device transmits a radio frequency signal which includes the unique identification code of the medicine monitoring device and a voice broadcasting request; the medicine taking reminding device receives the radio frequency signal, identifies the unique identification code of the medicine monitoring device and controls a voice module to broadcast a medicine taking reminding voice of the medicine binding with the medicine monitoring device according to the voice broadcasting request. The medicine monitoring and medicine taking reminding system has the advantages that after the medicine is bound withthe medicine monitoring device, when a patient operates the medicine container of the medicine or takes medicine, the medicine taking reminding device can broadcast the related medicine taking reminding voice to assist the patient to take the medicine, the situation that the patient takes the wrong medicine, takes excessive medicine or takes less medicine is avoided, and the patient can safely timely take the medicine according to the dose.

Methods and apparatus are provided for determining when a medication is removed from a dispenser. The dispenser may include a plurality of compartments for receiving one or more medications. One or more circuits are associated with each compartment. In addition, each circuit may be unique. Each circuit is altered by the removal of one or more medications from a compartment and the resulting signal is used to indicate removal of the medication.

A medical monitoring system extracts characteristic information for one or more medications from an image of the one or more medications on an uncontrolled background, the image being taken by a client device associated with a user of the medical monitoring system. The medical monitoring system determines prescription information associated with a medication, of the one or more medications, using the extracted characteristic information and a medication database, the medication database containing mappings between prescription information and characteristic information for a plurality of medications. The medical monitoring system provides a portion of the prescription information to the client device.

Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container. The method may further include transmitting based on the detection, a signal from a beacon to a remote device, which indicates the opening of the medication container.

A medication monitoring system including a patient information unit having a processor, a memory and a patient monitoring unit and a program executing in the memory executing the steps of communicatively coupling a first device with a second device, transmitting live images from the first device to the second device, analyzing the content of the live images to identify at least one biometric attribute of a user in the image and at least one bar code on a container in the image, determining whether the bar code is associated with at least one biometric attribute, and notifying the user whether to consume the contents of the container based on the association of the bar code with the biometric attribute.

The present invention relates to assisting patients in the taking of medication, and to assisting third parties in accumulating information regarding patient medication intake. The invention may be embodied a system including a portable medication monitor used in association with an instrumented medication package to provide intake data acquisition and patient support functions. The system may further be connected to a computer or computer network allowing information distribution between the medication monitor and third parties, such as physicians or pharmacists.

The invention belongs to the technical field of patrol robots, and discloses a mobile intelligent medicine delivering patrol robot. The robot comprises a robot body and an artificial intelligence platform; a detection device, a diagnosis device, a medicine distributing device, a medicine discharging device and a navigation device are respectively connected with a control system; the detection device comprises a warning device, a fingerprint verification device, a portrait recognition device and a cruise indicating lamp; the medicine distributing device comprises a medicine storage box device,a medicine distributing motor device, a medicine sorting and collecting box, a medicine sorting and conveying device, a medicine discharging control device and a connecting piece fixing device; the medicine discharging device comprises a medicine discharging device assembly, a guide rail device, a medicine discharging conveying device, a position angle servo driving device, a medicine delivering power device, a medicine fetching opening and a medicine discharging indicating lamp; and the navigation device comprises a laser radar, an obstacle avoidance sensor and a navigation system. The robothas the functions of autonomous cruise, automatic obstacle avoidance, intelligent patrol, automatic distribution, automatic proportioning, medication monitoring and the like, can be applied to hospitals, prison stations and other places, and has good practicability.

A system and method for informed prescribing implements a multiplex assay system to measure each of a plurality of chemical entities associated with a patient from a single body fluid sample, and identifies medication levels for each of the measured chemical entities relative to respective target ranges. A drug interaction program module such as a neutral network engine is iteratively trained using the identified medication levels and historical patient data from data storage. Program engines further measure an effectiveness of each of the chemical entities with respect to the historical patient data, and generate a recommended dosage for each of the plurality of chemical entities based on a drug interaction output from the drug interaction program module and the measured effectiveness. A user interface displays the results, and in an embodiment further provides alternative treatment options with respect to certain chemical entities based on drug interactions and / or effectiveness.

The claimed invention provides real-time and subsequent analysis personalized user based health, wellness and pharmaceutical and illicit drug detection information. Non-invasive techniques utilize saliva for body levels of wellness indicators and pharmaceutical and illicit drug ingestion which are coordinated over time. Saliva captured on sample strips are real-time indicator reviewed and subsequently analyzed using traditional analytical chemistry techniques including liquid chromatography / mass spectrometry (LC / MS) and coordinated with time of administration with optional genetic sequence analysis to confirm related disease conditions. By using P4 (Participatory, Personalized, Predictive, and Preventive) health management techniques the patient determines if the pharmaceutical is having the correct and desired effect for maximum therapeutic benefit. While illustrative embodiments detecting Metformin and Keppra are provided the system has broad pharmaceutical and illicit drug monitoring applicability.

The invention relates to the field of medical detection and in particular to a blood aripiprazole therapeutic drug monitoring kit developed based on multi-dimensional online solid-phase extraction liquid chromatography analytical technology, more specifically to a method for accurately and quantitatively detecting aripiprazole drug concentration in blood by online solid-phase extraction and multi-dimensional liquid chromatography analytical technology. The kit includes a calibration reagent, a quality control reagent, a processing liquid, an extract liquid, a washing liquid, and an eluent. Thetherapeutic drug monitoring kit of the invention only needs to centrifuge a blood sample, achieves low repeated detection variability, high accuracy and stability, and low detection cost, has variousmethodological indicators that satisfy the requirement for monitoring the blood aripiprazole therapeutic drugs, and is easy to generalize.

A decision support system and method for optimizing medication dosages includes comprehensive patient databases correlating medications and exposure values across data models having pharmacokinetic and pharmacodynamic dimensions. The system determines distinctions between expected and detected medications and exposure values for a patient, and further distinguishes between non-compliant patients from compliant patients having high metabolizing characteristics with respect to certain expected but undetected medications. The system links to and reconciles the patient medical record accordingly. Graphical user interfaces display recommended dosages and projected exposure ranges for the expected and detected medications. In an embodiment, the interface presents certain alternative treatment options determined as being available with respect to the expected but undetected medications. The user in an embodiment may manipulate or select respective nominal dosage values or alternative treatment options, wherein projected exposure values are dynamically calculated and displayed for each of the medications.

The invention relates to an intelligent medication monitoring device comprising a machine body, a medication monitoring system and a dispensing device; the dispensing device comprises multiple annularly distributed dispensing units and a medicine collecting mechanism; a medicine collecting cup of the medicine collecting mechanism successively moves to a medicine outlet of each dispensing unit forcollecting medicine; a medicine taking drive mechanism sends the medicine collecting cup which collects medicine to a medicine taking window; information of each dispensing unit is stored in partitionstorage and then in summary storage; the medication monitoring system performs information editing and viewing via a human-computer interaction unit; a central control unit receives signals of the network communication module and can perform remote video surveillance through the video call device; according to the medication information, a timed medication reminding unit is driven to realize themedication reminding and the dispensing device is controlled to complete the dispensing; users can flexibly change medication information and medication information, achieve presetting, and realize remote medication monitoring, assistance, and regular medication reminders to ensure that medications are taken on time.

A prescription medication monitoring system includes a card having a microprocessor and an RFID chip embedded therein. The chip and microprocessor are electrically connected to a text display and multi-digit display on the front surface of the card. The card operates in conjunction with a base terminal located at a participating pharmacy. The base terminal initially uploads a patient's prescription and personal information via a designated server. The terminal also scans the patient's finger to create a fingerprint image, and then records the uploaded information, including the scanned fingerprint image, onto the chip. Pertinent information relating to the prescription, such as medication name, dosage amount, dosage frequency and remaining authorized refills can be readily depicted on the displays. Each time the patient refills a prescription, the process is repeated and the pertinent prescription data, including any remaining authorized refills, is automatically updated and can be accessed via the text display.

The invention relates to the field of medical detection and in particular to a blood donepezil therapeutic drug monitoring kit developed based on multi-dimensional online solid-phase extraction liquidchromatography analytical technology, more specifically to a method for accurately and quantitatively detecting donepezil drug concentration in blood by online solid-phase extraction and multi-dimensional liquid chromatography analytical technology. The kit includes a calibration reagent, a quality control reagent, a processing liquid, an extract liquid, a washing liquid, and an eluent. The therapeutic drug monitoring kit of the invention only needs to centrifuge a blood sample, achieves low repeated detection variability, high accuracy and stability, and low detection cost, has various methodological indicators that satisfy the requirement for monitoring the blood donepezil therapeutic drugs, and is easy to generalize.

The present invention provides a method of standardization of chemical and therapeutic properties and quality of foods and medicines. The present invention provides a method of chromatographic finger printing facilitating correlation of traditional methods used for chemical and therapeutic standardization of medicines and humors in the living things with physico chemical properties of the medicines and their constituents. The method is used for the qualitative and quantitative analysis of the energy involved in the medicines and living things and to understand various bio chemical reactions in living things using an energy system. It provides a rational basis to understand the traditional methods of assessment of chemical and therapeutic qualities of materials used for the said purpose. The present invention also provides the influence, of factors like pH, temperature, viscosity and ionic nature of the media along with atomic and molecular properties indicating the chemical and therapeutic values of the foods and medicines of natural and synthetic nature. The analysis of biological samples like blood indicated the utility of the method for the assessment of clinical pathological conditions of healthy and diseased. This facilitates for a better drug discovery, drug monitoring, drug targeting and drug profiling using different features of 3-D animated energy box created after analyzing the sample by different analysis, separation and detection methods.

The invention provides a medicine monitoring device, system and method. The medicine monitoring device comprises a medicine holding container and a processing module, wherein the medicine holding container is used for holding medicines; and the processing module is used for analyzing and confirming the quantity and the type of original medicines in the medicine holding container and the quantity and the type of medicines taken out of the medicine holding container, and judging whether the medicines taken out of the medicine holding container are consistent with the preset quantity and type or not. According to the medicine monitoring device, system and method provided by the application, spectral characteristics of the medicines can be recognized by utilizing a Raman analysis instrument according to different spectrums, and the spectral characteristics are compared with a drug spectrum library in a storage module, the categories of all medicines can be obtained so as to achieve the effect that the problem of wrong intake for patients caused by misplacing medicines or taking medicine wrongly is solved; weight information of the medicines in a medicine box also can be monitored by utilizing a weightometer, and the patient is prompted to orally take the medicines in the oral administration time; and meanwhile, the situation that the quantity of intake medicines is consistent with the preset quantity is guaranteed.

The invention relates to kits and applications thereof, particularly relates to a kit for detecting copy number mutation of HER2 of CTCs based on ddPCR and a method and belongs to the technical fieldof nucleic acid detection. The kit for detecting the copy number mutation of the HER2 of the CTCs based on the ddPCR comprises a nucleotide sequence for detecting the copy number mutation of the geneHER2, primer pairs shown in SEQ ID NO: 1~6, a detecting probe 1, a detecting probe 2, a premix and calibration standard substances (including a negative reference substance and a positive reference substance). The kit is used for detecting cycling tumor cells and achieves noninvasive, high-sensitivity and high-accuracy real-time monitoring on tumor medication, medication monitoring, recurrence detection and the like. The kit has good absolute quantitative accuracy, sensitivity and repeatability to samples of a small input amount and has a good detection result to low-frequency mutations.

The invention belongs to the technical field of biological medicine and specifically relates to a rectal tumor marker which is Beclin1 protein, and application of a reagent for detecting expression level and / or phosphorylation level of the Beclin1 protein in the preparation of a kit used for detection and / or diagnosis of rectal tumor or used for treatment and / or prognostic evaluation of rectal tumor patients. The kit for detection and / or diagnosis of rectal tumor or treatment and / or prognostic evaluation of rectal tumor patients comprises the reagent for detecting expression level and / or phosphorylation level of the Beclin1 protein. Through joint evaluation of total level and phosphorylation level of the marker, the marker can be used as the reference for early detection and / or diagnosis of rectal tumor as well as the reference for medication monitoring and drug resistance prediction for rectal tumor patients.

The embodiment of the invention discloses a medication monitoring method and device based on data processing. The method comprises the following steps of: acquiring a medication prescription of a medical unit to be monitored; acquiring the medicine information of various medicines included in the medication prescription, and determining the daily average medicine cost of each medicine according tothe medicine information of various medicines; determining a target medicine in the medication prescription according to the single medicine daily average medicine cost of each medicine, and determining a target medicine proportion of the target medicine in the medication prescription according to the medicine information of each medicine; and determining whether the medication of the medical unit to be monitored reaches the standard according to the target medicine proportion and a medication standard threshold value corresponding to the medical unit to be monitored. By using the method, theaccuracy of the medication monitoring of the medical unit can be improved, the reliability of the medication monitoring of the medical unit can be improved, and the applicability is strong.

Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container. The method may further include transmitting based on the detection, a signal from a beacon to a remote device, which indicates the opening of the medication container.

A decision support system and method for optimizing medication dosages includes comprehensive patient databases correlating medications and exposure values across data models having pharmacokinetic and pharmacodynamic dimensions. The system determines distinctions between expected and detected medications and exposure values for a patient, and further distinguishes between non-compliant patients from compliant patients having high metabolizing characteristics with respect to certain expected but undetected medications. The system links to and reconciles the patient medical record accordingly. Graphical user interfaces display recommended dosages and projected exposure ranges for the expected and detected medications. In an embodiment, the interface presents certain alternative treatment options determined as being available with respect to the expected but undetected medications. The user in an embodiment may manipulate or select respective nominal dosage values or alternative treatment options, wherein projected exposure values are dynamically calculated and displayed for each of the medications.

An embodiment of the invention discloses a medical unit medication monitoring method and device based on data processing. The method includes obtaining a medication prescription of a medical unit to be monitored; obtaining patient information included in the medication prescription and determining the number of patients corresponding to the medication prescription according to the patient information; obtaining medicine information included in the medication prescription and determining daily average medicine cost per patient of the medical unit to be monitored according to the medicine information and the number of patients; determining whether the medication of the medical unit to be monitored meets the standard according to the daily average medicine cost per patient and a correspondingmedication standard threshold of the medical unit to be monitored. The method and device improve the accuracy and the reliability of the medication monitoring of the medical unit and achieve high adaptability.

The invention relates to the field of medicine detection, in particular to a kit, for therapeutic drug monitoring of fluconazole in blood, developed on the basis of a multi-dimensional online solid phase extraction and liquid chromatography analysis technology, and more specifically discloses a method for carrying out accurate quantitative detection on the concentration of a fluconazole drug in blood by adopting an online solid phase extraction and multi-dimensional liquid chromatography analysis technology. The kit comprises a calibrator reagent, a quality control material reagent, treating fluid, extracting fluid, cleaning fluid and an eluent. According to the kit for therapeutic drug monitoring disclosed by the invention, only centrifugal treatment is needed for a blood sample, so thatthe repeated detection variability is small, the accuracy and the stability are high, the detection cost is low, and various methodology indicators all can meet the requirements of therapeutic drug monitoring of the fluconazole in the blood, and the kit is easy to promote.

The embodiment of the invention discloses a method and device for prewarning drug cost exceeding standard based on data processing. The method comprises: obtaining medication prescriptions for medicalunits to be monitored; acquiring drug information of various drugs included in the medication prescriptions, and determining the single drug daily average drug cost of the various drugs according tothe drug information of the various drugs; determining a target drug in the medication prescriptions according to the single drug daily average drug cost of each drug, and determining the proportion of the target drug according to the drug information of each drug; determining whether or not the target drug proportion is greater than or equal to a target drug proportion threshold value corresponding to a medical unit to be monitored; if the target drug proportion is greater than or equal to the target drug proportion threshold value, sending the drug expense exceeding warning information to the medical units to be monitored. By adopting the method, the timeliness of the medication monitoring of the medical units can be improved, the reliability of the medication monitoring of the medical units can be enhanced, the effective utilization rate of medical resources can be improved, and the applicability is strong.

The claimed invention provides real-time and subsequent analysis personalized user based health, wellness and pharmaceutical and illicit drug detection information. Non-invasive techniques utilize saliva for body levels of wellness indicators and pharmaceutical and illicit drug ingestion which are coordinated over time. Saliva captured on sample strips are real-time indicator reviewed and subsequently analyzed using traditional analytical chemistry techniques including liquid chromatography / mass spectrometry (LC / MS) and coordinated with time of administration with optional genetic sequence analysis to confirm related disease conditions. By using P4 (Participatory, Personalized, Predictive, and Preventive) health management techniques the patient determines if the pharmaceutical is having the correct and desired effect for maximum therapeutic benefit. While illustrative embodiments detecting Metformin and Keppra are provided the system has broad pharmaceutical and illicit drug monitoring applicability.