The invention discloses a master-slave isomorphic teleoperation main hand of a laparoscope minimally-invasive surgery robot. The master-slave isomorphic teleoperation main hand mainly comprises a base, a universal joint mechanism assembly I, universal joint mechanism assemblies II, III and IV, a thumb part and an index finger part, wherein the universal joint mechanism assembly I is arranged on the base; the universal joint mechanism assemblies II, III and IV, the thumb part and the index finger part are sequentially and correspondingly connected through joint connecting parts; and the universal joint mechanism assemblies I, II, IIII and IV are correspondingly provided with angle sensors S1, S2, S3, S4, S5, S6 and S7. The freedom degrees of all joints on the teleoperation main hand correspond to the motion freedom degrees of surgical instruments at a surgery executing end one to one, so that master-slave isomorphism is realized, the surgery executing end can be directly controlled and regulated by the teleoperation main hand according to a corresponding (mapping) relationship, the motion analysis time required by master-slave isomeric teleoperation is avoided, and the system delay is reduced; in addition, the intuition of teleoperation is also enhanced, and the operation difficulty and errors are effectively reduced.